Stem Cells

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07.08.2026
08:22 News-Medical.Net Scientists map key differences in stem cell potency for treating knee osteoarthritis

Knee osteoarthritis (KOA) affects more than 1 in 10 people over 40 years of age, impairing patients' mobility and quality of life.

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05:16 News-Medical.Net PIWI proteins and piRNAs may unlock more effective stem cell therapies

Scientists are shedding new light on a little-known biological system that could help unlock the full potential of stem cell therapy, one of the most promising areas of modern medicine.

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06.08.2026
06:29 News-Medical.Net Neural stem cells split early into distinct neuron lineages

The cerebral cortex is densely packed with different nerve cells that enable us to perceive, think and act. Yet how these cell types arise while the brain develops is still not fully understood.

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05.08.2026
14:44 Medscape.Com Stem Cell Transplant Boosts Survival in Primary CNS Lymphoma

Among patients with primary CNS lymphoma who respond to induction therapy, high-dose chemotherapy with stem cell transplant improves survival compared with nonmyeloablative chemotherapy.

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04.08.2026
06:16 News-Medical.Net Child-friendly lung test identifies subtle abnormalities before stem cell transplant

As spirometry requires coordinated deep breathing and can be challenging for children to perform, researchers from the USA, as part of the TRANSPIRE study investigating lung complications in children undergoing hematopoietic stem cell transplantation (HSCT), explored the potential of oscillometry, a simple and child-friendly lung function test.

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03.08.2026
06:24 Nature.Com Sickle-cell disease linked to prematurely aged stem cells in mice

Nature is the foremost international weekly scientific journal in the world and is the flagship journal for Nature Portfolio. It publishes the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature publishes landmark papers, award winning news, leading comment and expert opinion on important, topical scientific news and events that enable readers to share the latest discoveries in science and evolve the discussion amongst the global scientific community.

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01.08.2026
20:24 News-Medical.Net TRF2 protein preserves muscle stem cell identity and regeneration

A protein best known for protecting the ends of chromosomes also helps muscle stem cells preserve their identity and repair damaged tissue, according to a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

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31.07.2026
19:33 News-Medical.Net New stem cell vesicles accelerate diabetic wound healing

Diabetic foot ulcers are among the most serious complications of diabetes because prolonged inflammation, poor circulation, and defective angiogenesis can leave wounds open for months and increase the risk of infection and amputation.

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30.07.2026
01:24 Phys.org Keeping stem cells in check: A new mechanism by which cell junction proteins regulate tissue homeostasis

In many animal tissues, stem cells continually divide to create new cells that replace old or damaged ones. However, this capacity requires strict regulation, as uncontrolled stem cell proliferation can disrupt tissue homeostasis and contribute to tumorigenesis.

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29.07.2026
19:03 Nature.Com Intestinal stem cells count to eight divisions to maintain cell ratios

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19:03 Nature.Com Intestinal stem cells count self-renewal divisions to switch multipotency

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05:52 News-Medical.Net Cell junction proteins regulate stem cell signaling and tissue homeostasis

In many animal tissues, stem cells continually divide to create new cells that replace old or damaged ones. However, this capacity requires strict regulation, as uncontrolled stem cell proliferation can disrupt tissue homeostasis and contribute to tumorigenesis.

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24.07.2026
16:12 Medscape.Com Stem Cell Transplant Associated With Better PFS in NKTCL

Researchers aim to evaluate the effectiveness of ASCT as consolidation therapy for patients with advanced-stage natural killer/T-cell lymphoma who have attained their first complete remission.

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23.07.2026
12:33 Medscape.Com Stem Cell Therapy Shows Early Promise in Parkinson’s Disease

Stem cell-derived dopamine cell transplantation appears feasible and may reduce medication needs in PD, but longer follow-up is needed to establish its clinical benefit and long-term safety.

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06:04 News-Medical.Net Senolytic drugs rejuvenate blood stem cells in sickle cell disease

Sickle cell disease causes premature aging of blood stem cells, which scientists may be able to address with a special class of drugs, according to a new study from St. Jude Children's Research Hospital.

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20.07.2026
03:01 Phys.org Generating red blood cell-like cells from canine induced pluripotent stem cells

Blood transfusions are crucial in human and veterinary medicine, yet human blood reserves are in constant need of donors, while blood bank systems in veterinary care are nearly nonexistent. This leaves canine transfusions largely reliant on donations from healthy dogs, but securing compatible blood remains a major challenge because dogs also have different blood types.

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13.07.2026
19:52 News-Medical.Net New genetic reference map accelerates human stem cell research

A team led by bioengineers at the University of California San Diego has developed a genome-scale reference map that details how individual genes control the functions and identities of human stem cells.

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17:41 Phys.org 2.5 million stem cells reveal first genome-scale guide to gene function

A team led by bioengineers at the University of California San Diego has developed a genome-scale reference map that details how individual genes control the functions and identities of human stem cells. This open-access resource could help researchers build virtual cell models for complex diseases, as well as design patient-specific treatments for these diseases.

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10:14 Technology.org Stem Cell scientists engineer “synthetic organizer” cells to improve kidney organoids

Mapping the human kidney, researchers discovered an unrecognized developmental axis and engineered “synthetic organizer” cells to recreate key

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11.07.2026
21:30 News-Medical.Net New stem cell approach targets functional cure for diabetes

New research presented today at the International Society for Stem Cell Research (ISSCR) 2026 Annual Meeting explores an approach that could expand the potential of cell replacement therapy for type 1 diabetes by evaluating whether immune-engineered, allogeneic insulin-producing cells can survive and function without chronic immunosuppression.

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14:58 News-Medical.Net New stem cell therapy offers hope for chronic spinal injury

New research presented today at the International Society for Stem Cell Research (ISSCR) 2026 Annual Meeting highlights a significant step toward developing a stem cell-based treatment for chronic spinal cord injury (SCI), a condition for which no effective restorative therapy currently exists.

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10.07.2026
06:37 News-Medical.Net Stem cell-derived dopaminergic cell transplantation shows encouraging results for Parkinson's disease

The International Society for Stem Cell Research (ISSCR) today announced the presentation of new clinical data from the STEM-PD Phase I/II clinical trial at the ISSCR 2026 Annual Meeting.

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01:41 GenEngNews.com Stem Cell Therapy Shows Promise in First Human Parkinson’s Disease Trial

One year findings from Phase I/II clinical study support the feasibility of transplanting stem-cell derived dopamine progenitor cells into the brain of Parkinson’s disease patients. The post Stem Cell Therapy Shows Promise in First Human Parkinson’s Disease Trial appeared first on GEN - Genetic Engineering and Biotechnology News.

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09.07.2026
21:58 News-Medical.Net Stem cell study uncovers molecular pathway for enamel regeneration

Tooth enamel is the hardest substance in the human body, yet once damaged, it cannot regenerate naturally.

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20:47 News-Medical.Net Clinical trial finds stem cell brain transplants feasible for Parkinson's disease

A landmark study led from Lund, Sweden, has shown that transplanting stem-cell derived dopamine progenitor cells into the brain is feasible.

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20:47 News-Medical.Net First clinical trial evaluates stem cell therapy for Huntington's disease

An update on the first clinical trial evaluating a pluripotent stem cell-derived neural stem cell therapy for Huntington's disease was presented today at the ISSCR 2026 Annual Meeting.

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08.07.2026
22:51 GenEngNews.com Epitope Editing Strategy Could Enable Less Toxic Stem Cell Transplants

Researchers developed an epitope editing strategy to make donated stem cells invisible to pre-transplant antibody therapy, offering up a new approach that could make antibodies a less toxic alternative to chemotherapy for selectively clearing the patient’s existing stem cells from the bone marrow. The post Epitope Editing Strategy Could Enable Less Toxic Stem Cell Transplants appeared first on GEN - Genetic Engineering and Biotechnology News.

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21:21 News-Medical.Net Novel strategy can make stem cell transplants safer

Stem cell transplantation (also called bone marrow transplantation) and gene therapy are among the most powerful curative approaches for blood diseases such as sickle cell disease, b-thalassemia, immune deficiencies, and some blood cancers.

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07.07.2026
21:38 FightAging.org Retinal Endothelial Cells Derived from Induced Pluripotent Stem Cells Repair Damaged Retinas in Mice

The retina is considered a part of the central nervous system. As is the case for the brain, a barrier of specialized cells surrounding the blood vessels supplying retinal tissue controls the passage of molecules between blood and tissues. This barrier becomes dysfunctional with age and age-related conditions, and leaks inappropriate molecules into retinal tissue to cause further damage and dysfunction. Again, this is very analogous to barrier dysfunction in the brain, and is thought to be a major contributing factor in age-related neurodegeneration and consequent degenerative conditions. One of the approaches under development for the treatment of damaged retinal tissue, such as in the context of macular degeneration or diabetic retinopathy, is to produce new cells that can replace dead or dysfunctional cells, or […]

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13:37 FightAging.org Age-Related Cellular Senescence Harms Stem Cell Function

The growth in number of senescent cells with age is an important mechanism of degenerative aging. Many studies in mice have demonstrated rapid rejuvenation and reversal of many different aspects of aging and age-related conditions via selective destruction of senescent cells in aged tissues. Here, researchers review what is known of the way in which the age-related expansion of the senescent state in cell populations impedes stem cell function in older individuals. Stem cells support tissues by generating a supply of daughter somatic cells to replace losses, as well as via signaling that is important to regenerative capacity. As stem cell activity declines so too does tissue function and health. Several cellular settings have been identified where senescence induction seems to exclude stem cell activity, […]

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02.07.2026
23:23 GenEngNews.com Synthetic Organizers Aid Creation of Reproducible Kidney Organoids from Stem Cells

Using techniques including spatial transcriptomics, researchers identified a developmental axis that helps organize developing kidney nephrons, and engineered Wnt-secreting “synthetic organizer” cells to recreate aspects of this developmental environment in organoids created from stem cells. The post Synthetic Organizers Aid Creation of Reproducible Kidney Organoids from Stem Cells appeared first on GEN - Genetic Engineering and Biotechnology News.

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13:16 FightAging.org Evidence for Hematopoietic Progenitor Cells to Buffer the Aging of Hematopoietic Stem Cells

Hematopoietic cell populations reside in the bone marrow. A tree of ever more specialized progenitor cell populations descends from the root hematopoietic stem cell population, responsible for ultimately producing red blood cells and white blood cells. Hematopoietic stem cell populations are known to become damaged and dysfunction with age, and this is one of the contributions to immune system dysfunction in later life. It also produces effects such as platelets that are more prone to causing inappropriate clotting and thrombosis. Here, researchers provide evidence to suggest that the intermediate hematopoietic progenitor cell populations are much less impacted by aging than is the case for hematopoietic stem cells, and might be buffering the loss of stem cell function to allow for maintained hematopoietic function. It is […]

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08:36 News-Medical.Net Simple donor message could expand stem cell transplant options

When a patient needs a stem cell transplant, finding a registered donor is only the first step. Some potential donors drop out before confirmatory typing, reducing the pool from which doctors can choose.

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30.06.2026
17:35 News-Medical.Net Duke engineers grow retinal blood vessel cells from pluripotent stem cells

Biomedical engineers at Duke University have used induced pluripotent stem cells (iPSCs) to grow specialized blood vessel cells critical to retinal health for the first time.

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29.06.2026
13:38 FightAging.org A Review of the State of Stem Cell Therapies

Researchers here review the state of stem cell therapies for the treatment of age-related degenerative conditions, with particular attention to more recently emerged areas of the field such as efforts to rejuvenate old patient-derived stem cells before their use in therapy. Partial epigenetic reprogramming is not much mentioned in this context as, unlike the use of senolytics, it has not yet advanced to the point of ease of use for the average stem cell clinic. Treating a stem cell culture with cheap and well-established senolytic compounds is very much more feasible in comparison to the time, expertise, and expense needed to safely and reliably partially reprogram cells in that same culture. Rejuvenation strategies for ageing stem cells focus on restoring their regenerative capabilities, which decline […]

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25.06.2026
22:21 Phys.org Stem cell education platform strengthens students' identity as scientists

On a YouTube livestream, Berkeley City College students carefully study the movements of stem cells to observe what they do as they become neurons: Are they moving, growing or forming new connections with other neurons?

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24.06.2026
23:23 GenEngNews.com First-in-Human Stem Cell Therapy Trial for Huntington’s Disease Begins at UCI Health

UCI Health has launched the world’s first human clinical trial using embryonic stem cell-derived neural cells for Huntington’s disease, testing MRI-guided surgical brain delivery to evaluate safety and early therapeutic potential. The post First-in-Human Stem Cell Therapy Trial for Huntington’s Disease Begins at UCI Health appeared first on GEN - Genetic Engineering and Biotechnology News.

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20:12 GenEngNews.com Scaling Stem-Cell Manufacturing for Therapies

As more than 100 clinical trials test human pluripotent stem cell-derived therapies, researchers are shifting focus from proving large-scale production is possible to building standardized, AI-enabled manufacturing systems capable of delivering consistent, clinically compliant cell products. The post Scaling Stem-Cell Manufacturing for Therapies appeared first on GEN - Genetic Engineering and Biotechnology News.

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23.06.2026
19:25 News-Medical.Net UCI Health launches world's first embryonic stem cell trial for Huntington's disease

UCI Health, the clinical enterprise of the University of California, Irvine, has opened the world's first in-human embryonic stem cell-derived clinical trial for Huntington's disease.

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00:20 FightAging.org A Combination Senolytic and Stem Cell Therapy Assessed in a Mouse Model of Aging

Senescent cells accumulate with age, a situation that appears more a result of the aging immune system failing to achieve timely clearance of newly senescent cells rather than a significant increase in the pace at which cells become senescent. Senescence occurs in response to cellular damage and stress, but also when somatic cells reach the Hayflick limit on replication. A senescent cell becomes larger, ceases replication, and devotes its energies to the secretion of pro-growth, pro-inflammatory signals. In the short term and in youth this is usually beneficial, helping to coordinate tissue maintenance, regeneration, and suppression of potentially cancerous cells. When sustained for the long term, the signaling of senescent cells is disruptive to tissue structure and function, however, contributing to the damaging chronic inflammation […]

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22.06.2026
18:19 ScientificAmerican.Com Stem cells banish severe autoimmune disease for 15 years

Two people were the first to receive the therapy for a condition that damages the spinal cord and optic nerve

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19.06.2026
04:49 Nature.Com Stem cells banish severe autoimmune disease for 15 years

Nature is the foremost international weekly scientific journal in the world and is the flagship journal for Nature Portfolio. It publishes the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature publishes landmark papers, award winning news, leading comment and expert opinion on important, topical scientific news and events that enable readers to share the latest discoveries in science and evolve the discussion amongst the global scientific community.

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12.06.2026
10:40 Medscape.Com In MS, Stem Cell Transplant Sometimes Looks Like Cure

Autologous hematopoietic stem cell transplant at experienced centers in the current era can include indefinite disease control with low relative risk, a new update suggests.

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09.06.2026
17:45 Drugs.com MAHA's Treatments For Autism: Camel's Milk, Stem Cell Injections — And Spelling Therapy

TUESDAY, June 9, 2026 — Elizabeth Bonker is a silent woman with a loud mission. She wants government agencies to cover the costs of training people with autism in a form of communication called assisted spelling. One problem: Leading professional...

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02:35 Phys.org How plants survive constant DNA damage: Newly identified repair protein protects growth-critical stem cells

Similar to the way DNA damage can contribute to human diseases such as cancer, it can also disrupt growth, development and survival in plants. Every day, plants endure environmental stresses such as sunlight, radiation, drought and soil stress—all of which can damage their DNA. However, they cannot move away from danger. How do plants handle all that damage?

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02.06.2026
22:15 News-Medical.Net Modified stem cell therapy reverses new-onset Type 1 diabetes in mice

A group of researchers at the Medical University of South Carolina (MUSC) has recently developed a new stem cell therapy with a remarkable ability to reverse new-onset Type 1 diabetes (T1D) in a mouse model of the disease.

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19:50 News-Medical.Net Stem cell transplantation is the most cost-effective sickle cell treatment

Stem cell transplantation is the most cost-effective option for long-term care of sickle cell disease in adults when compared with gene therapy and standard of care treatment, according to new research published in Blood.

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16:55 Phys.org Biohybrid microrobots repair spinal cord by combining stem cells with magnetoelectric nanoparticles

Spinal cord injuries can have devastating consequences for those affected. Nerve cells in the spinal cord rarely regenerate naturally, while scarring often prevents the regrowth of nerve fibers. Modern therapies attempt to influence implanted stem cells using electrical stimulation to promote the growth of new nerve cells. This approach has several drawbacks: it requires implanted electrodes, and the transplanted cells do not always survive or integrate properly into the existing tissue.

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15:32 News-Medical.Net Magnetic microrobots deliver stem cells to heal spinal cord injuries

A research team from ETH Zurich and the University of Zurich (UZH) has developed a novel approach to treating spinal cord injuries: controllable microrobots deliver stem cells directly to the site of an injury, where they promote nerve cell regeneration.

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01.06.2026
21:45 News-Medical.Net Mature intestinal cells regain stem cell behavior to trigger tumor growth

In a groundbreaking study, Stevens researchers show how colorectal cancers can evolve from mature intestinal cells that revert to stem cells.

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18:11 Phys.org New 'SMArT' platform makes gene editing in hematopoietic stem cells more efficient and safer

A team of researchers led by Luigi Naldini at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget) has developed a new strategy to significantly improve the precision and safety of CRISPR-Cas9 gene editing in human blood stem cells, potentially overcoming one of the major barriers limiting broader clinical application of genome editing therapies.

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27.05.2026
19:02 Nature.Com Human blood stem cells remember previous inflammation

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19:02 Nature.Com Human haematopoietic stem cells remember inflammatory stress

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13:07 Nature.Com Author Correction: Modelling late gastrulation in stem cell-derived monkey embryo models

Nature is the foremost international weekly scientific journal in the world and is the flagship journal for Nature Portfolio. It publishes the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature publishes landmark papers, award winning news, leading comment and expert opinion on important, topical scientific news and events that enable readers to share the latest discoveries in science and evolve the discussion amongst the global scientific community.

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20.05.2026
05:06 News-Medical.Net Methylene blue enhances hair follicle stem cell regeneration under stress

A new research paper was published in Volume 18 of Aging-US on May 5, 2026, titled "Methylene blue protects hair follicle stem cells from oxidative and metabolic stress to enhance hair regeneration."

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19.05.2026
06:57 News-Medical.Net Stem cell infusions improve symptoms in butterfly skin disease

The intravenous infusion of mesenchymal stem cells from family donors is safe and improves symptoms such as pruritus (itching), sleep disturbances, and fatigue associated with Recessive Dystrophic Epidermolysis Bullosa (RDEB), popularly known as "butterfly skin".

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14.05.2026
16:59 NewScientist.Com Rebooting stem cells builds aged muscles and assists injury recovery

Muscle stem cells, which are crucial for building new muscle, don’t work as well as we get older, but giving them an artificial boost could rejuvenate them

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13.05.2026
04:50 ScienceDaily.com Scientists make old blood stem cells young again in major anti-aging breakthrough

As blood stem cells age, their lysosomes become overactive and damaged, triggering inflammation and weakening the body’s ability to regenerate healthy blood and immune cells. By calming this cellular “overdrive,” researchers restored the stem cells’ youthful function, dramatically boosting their ability to regenerate and produce balanced blood cells.

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12.05.2026
22:52 GenEngNews.com Acute Myeloid Leukemia Therapy Improved by CRISPR Stem Cell Transplant

A Phase I/II clinical trial shows that a stem cell transplant that removes CD33 from donor cells using CRISPR can prevent cancer recurrence. The post Acute Myeloid Leukemia Therapy Improved by CRISPR Stem Cell Transplant appeared first on GEN - Genetic Engineering and Biotechnology News.

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20:35 News-Medical.Net Intestinal stem cells identified as active defenders against Salmonella infection

Researchers from the Hebrew University of Jerusalem and the Weizmann Institute of Science have identified a previously unrecognized defense mechanism in the intestine, showing that intestinal stem cells can actively respond to Salmonella infection and help protect the gut from bacterial invasion.

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16:07 Phys.org Two proteins, one goal: New findings on stem cell differentiation

Stem cells are the original cell type from which all other cells and tissues in the body develop through a very tightly regulated process. However, how stem cells differentiate in addition to gene-control systems, such as canonical REST repression, which prevents gene expression in inappropriate tissues, has remained unknown.

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13:46 News-Medical.Net Two proteins help maintain stem cells by preventing differentiation

Researchers from The University of Osaka find that the zinc finger proteins RLF and ZFP292 assist in stabilizing the CoREST corepressor complex at gene promoters in embryonic stem cells, preventing differentiation.

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08.05.2026
06:23 News-Medical.Net Diverse leukemia stem cells may drive AML relapse after therapy

Scientists from the German Cancer Research Center (DKFZ) and the HI-STEM* Stem Cell Institute have deciphered a key mechanism that contributes to treatment failure in acute myeloid leukemia (AML).

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07.05.2026
13:21 FightAging.org More Evidence for Muscle Stem Cell Activity to be Inhibited by the Aged Tissue Environment

Stem cells support tissues by generating a supply of daughter somatic cells to replace losses. A broad body of evidence points to reduced muscle stem cell activity as a major contributing cause of age-related loss of muscle mass and strength. Other evidence suggests that this stem cell population remains capable; when old muscle stem cells are removed from the aged tissue environment for assessment, they appear to be as capable as young muscle stem cells. Researchers are now interested in establishing how an aged environment interacts with muscle stem cells to reduce their activity, with an eye to developing therapies to interfere in specific mechanisms as they are uncovered. Frailty arising from loss of muscle function and mass is a significant health concern impacting quality […]

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06.05.2026
11:04 Technology.org Stem cell model of human embryo produces yolk sac without hypoblasts or genetic trickery

For the first time, a stem cell model has produced a structure resembling an early human embryo with

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05.05.2026
01:35 GenEngNews.com Blood Stem Cells Evade Immune Attack in Aplastic Anemia Through Gene Mutations

Among individuals with aplastic anemia, different blood stem cells in the same person independently acquire gene mutations allowing escape from immune attack, and for some people these “rescuing” stem cell clones are sufficient to restore blood production and enable long-term remission. The post Blood Stem Cells Evade Immune Attack in Aplastic Anemia Through Gene Mutations appeared first on GEN - Genetic Engineering and Biotechnology News.

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02.05.2026
07:23 News-Medical.Net Study shows eIF4G2 gene maintains adult intestinal stem cell identity

Years before he conducted the research that would earn him a Nobel Prize in Physiology and Medicine, Shinya Yamanaka, MD, PhD, was a postdoctoral scientist at Gladstone Institutes, studying genes.

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30.04.2026
04:25 GenEngNews.com Restoring Vision with Stem Cell–Derived Retinal Cells by Overcoming ILM Barrier

Disrupting the eye’s internal limiting membrane enables transplanted stem cell–derived retinal ganglion cells to survive, migrate, and form connections, offering a potential future treatment for optic nerve damage. The post Restoring Vision with Stem Cell–Derived Retinal Cells by Overcoming ILM Barrier appeared first on GEN - Genetic Engineering and Biotechnology News.

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29.04.2026
17:21 Drugs.com Pooled Umbilical Cord Blood Boosts Stem Cell Transplant Success, Trial Finds

WEDNESDAY, April 29, 2026 — A new way of using umbilical cord blood — by pooling blood from multiple donors — could make it easier to receive a stem cell transplant for leukemia, a new study says.Nearly everyone in a small group of patients who rece...

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27.04.2026
13:37 FightAging.org Evidence for MLKL to be Important in Hematopoietic Stem Cell Aging

Researchers here identify a common mechanism in the cellular responses to various forms of stress that appears to drive aspects of hematopoietic stem cell aging via impairment of mitochondrial function. Hematopoietic cells are responsible for generating immune cells and red blood cells. Aging produces alterations in the character and lineages of generated cells, contributing to dysfunction in the immune system and in platelet producing cells, among other issues. Suppressing some aspects of cellular stress responses, those that become maladaptive in the aged tissue environment, may prove to be useful as a basis for therapy. It nonetheless seems a poor alternative to instead repairing or otherwise addressing the forms of damage and dysfunction that provoke these excessive cell stress responses. Hematopoietic stem cells (HSCs) survive many […]

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26.04.2026
18:42 News-Medical.Net International consortia honored for advancing stem cell research collaboration

The International Society for Stem Cell Research (ISSCR) has named CorEUstem COST Action and Stem Cell COREdinates as the recipients of the 2026 ISSCR Public Service Award.

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25.04.2026
09:52 News-Medical.Net ISSCR urges NIH to continue support human embryonic stem cell research

The International Society for Stem Cell Research (ISSCR) has submitted a formal response to a Request for Information (RFI) issued by the National Institutes of Health (NIH) regarding its pause on new submissions to the NIH Human Embryonic Stem Cell (hESC) Registry and considerations to reduce reliance on hESCs in federally supported research.

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24.04.2026
14:21 NewScientist.Com Is stem cell therapy about to transform medicine and reverse ageing?

A clinical trial to reverse age-related vision conditions using stem cell treatment could finally deliver on the promise of a major discovery in ageing and regeneration made 20 years ago, says columnist Graham Lawton

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02:42 Phys.org New bioreactor turns stem cells into an immune-cell factory, producing 40 million human macrophages per week

Researchers at Hannover Medical School (MHH) have developed a method for the efficient production of human immune cells, such as macrophages, in medium-sized bioreactors. These immune cells can be derived from induced pluripotent stem cells and are important for disease research and the development of new therapeutic approaches. The method has now been published in the journal Nature Protocols.

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22.04.2026
04:38 News-Medical.Net Stem cell model recreates early human embryo with yolk sac

For the first time, a stem cell model has produced a structure resembling an early human embryo with a yolk-sac-like structure, from a single starting stem cell population and without direct genetic manipulation.

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21.04.2026
00:27 Phys.org Stem cell embryo model grows yolk sac without hypoblasts or gene editing

For the first time, a stem cell model has produced a structure resembling an early human embryo with a yolk-sac-like structure, from a single starting stem cell population and without direct genetic manipulation. The models were made at University of Michigan Engineering. Researchers at the Chinese Academy of Sciences provided monkey embryo data to help confirm that the Michigan team was indeed seeing a yolk-sac-like structure in their models. The work is published in the journal Nature Cell Biology.

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18.04.2026
08:11 News-Medical.Net Stem cell model identifies promising therapy for inflammatory bowel disease

A new study published today in Stem Cell Reports demonstrates how a human stem cell-derived model of the intestine can be used to identify potential therapies for inflammatory bowel disease (IBD), highlighting glycyrrhizin as a promising candidate for reducing intestinal inflammation and cell death.

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02:15 SingularityHub.Com Norwegian Man Cured of HIV by His Brother’s Stem Cells

Fewer than 10 people worldwide have eradicated the virus with stem cells. But this case was special—no one knew his brother's cells carried a protective mutation until transplant day. The post Norwegian Man Cured of HIV by His Brother’s Stem Cells appeared first on SingularityHub.

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17.04.2026
04:59 GenEngNews.com Stem Cell Editing Programs the Immune System to Make Own Therapeutic Proteins

A new gene‑editing strategy programs hematopoietic stem cells to produce therapeutic antibodies and other proteins. The approach generates long‑lasting immunity in mice and could point to single‑vaccine treatments for diverse diseases in the future. The post Stem Cell Editing Programs the Immune System to Make Own Therapeutic Proteins appeared first on GEN - Genetic Engineering and Biotechnology News.

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16.04.2026
21:29 GenEngNews.com Advances in Stem Cell‑Derived Insulin‑Producing Cells for Type 1 Diabetes

Researchers developed an improved method for creating insulin-producing cells from human stem cells, which effectively regulated blood sugar levels in laboratory tests and reversed diabetes in a mouse model. The post Advances in Stem Cell‑Derived Insulin‑Producing Cells for Type 1 Diabetes appeared first on GEN - Genetic Engineering and Biotechnology News.

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14.04.2026
00:20 LiveScience.com 'Oslo patient' likely cured of HIV after getting stem cell transplant from his brother, who is genetically resistant to the virus

A man known as the "Oslo patient" joins a short list of people in long-term remission from HIV following bone marrow transplants.

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12.04.2026
13:53 News-Medical.Net Pseudogene lncRNAs regulate cancer stem cell behavior and signaling

Cancer stem cells (CSCs), a critical subpopulation within tumors, drive cancer initiation, progression, metastasis, relapse, and resistance to therapy due to their innate capacity for self-renewal and differentiation.

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10.04.2026
05:44 News-Medical.Net Study maps DNA methylation changes driving MDS stem cell dysfunction

Published on April 01, 2026, in Volume 2, article number 19 of the journal Immunity & Inflammation, a collaborative team led by Prof. Cao at the Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, along with Dr. Liangding Hu at the Fifth Medical Center of Chinese PLA General Hospital, and Professors Qian Zhang and Yanmei Han at the National Key Laboratory of Immunity and Inflammation, Naval Medical University, has generated the first base-resolution DNA methylome of human MDS HSCs.

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09.04.2026
05:45 News-Medical.Net Stem cell study identifies universal checkpoint controlling cell identity

A study published in Cell Research advances a central idea in stem cell biology by identifying a checkpoint that controls the identity of many different types of stem cells across developmental stages.

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03:12 Phys.org A 'stemness checkpoint' helps control stem cell identity

A study published in Cell Research advances a central idea in stem cell biology by identifying a checkpoint that controls the identity of many different types of stem cells across developmental stages. For nearly two decades, scientists have understood that stem cell self-renewal depends on blocking differentiation signals—a concept described in earlier work, including Qi-Long Ying and Austin Smith's 2008 Nature paper titled "The ground state of embryonic stem cell self-renewal."

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08.04.2026
23:27 GenEngNews.com Scalable Embryonic Stem Cell Platform Enables Mitochondrial DNA Research in Mice

Researchers say the platform represents a strategically valuable foundation for accelerating therapeutic development through genetically precise mitochondrial disease models. The post Scalable Embryonic Stem Cell Platform Enables Mitochondrial DNA Research in Mice appeared first on GEN - Genetic Engineering and Biotechnology News.

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20:45 News-Medical.Net New MRI method tracks transplanted heart stem cells for months

Researchers at the Institute of Biomedical Engineering at the University of Toronto have demonstrated a new way to monitor transplanted stem-cell-derived heart cells using magnetic resonance imaging (MRI).

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07.04.2026
23:26 Phys.org How stem cell descendants preserve flexibility while maintaining distinct identities

Stem cells are the body's ultimate shape-shifters, sustaining tissues by balancing two competing demands: maintaining their own population and generating specialized descendants. In many tissues, some early descendants can revert to a stem cell state through a process known as dedifferentiation. This ability can help replenish the stem cell pool when stem cells are lost.

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02.04.2026
00:43 GenEngNews.com Biological Complexity of ALS to Be Addressed by the Development of New Stem Cell Models

PRISM ALS aims to develop, evaluate, and make available a diverse panel of well-characterized, patient-derived induced pluripotent stem cell (iPSC) models that capture both genetic and sporadic forms of ALS. The post Biological Complexity of ALS to Be Addressed by the Development of New Stem Cell Models appeared first on GEN - Genetic Engineering and Biotechnology News.

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01.04.2026
09:01 News-Medical.Net PRISM ALS: A new global collaboration to expand patient-derived stem cell models and accelerate treatments

A new global initiative launched today aims to close a critical gap in ALS/MND drug discovery - current cell models used for testing treatments do not currently reflect the diverse nature of the disease - that affects both researchers developing therapies and the people urgently waiting for them.

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31.03.2026
22:11 News-Medical.Net New stem cell therapy offers permanent cure for Hirschsprung disease

Scientists are developing a revolutionary new stem cell therapy to treat a rare and life-threatening disease that leaves newborn babies unable to function without invasive surgery, thanks to a collaboration between UCL, the University of Sheffield and Queen's University Belfast.

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30.03.2026
04:46 News-Medical.Net Chronic colitis reshapes colon stem cells in ways that can accelerate tumour growth

Researchers showed that chronic colitis leaves a long-lasting epigenetic memory in colonic stem cells, persisting for more than 100 days after recovery in mice. This memory is marked by durable AP-1-linked chromatin changes and later amplifies tumour outgrowth after oncogenic mutation.

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27.03.2026
18:23 GenEngNews.com Stem Cells at the Frontier: Breakthroughs, Barriers, and What’s Next

This GEN Live show will focus on new areas of stem cell research, including aging. It will bring together a panel of leading experts to unpack the latest advances and ongoing challenges in stem cells. The post Stem Cells at the Frontier: Breakthroughs, Barriers, and What’s Next appeared first on GEN - Genetic Engineering and Biotechnology News.

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25.03.2026
21:42 FightAging.org Aging Impairs Activation of Muscle Stem Cells, with MG53 as a Potential Target for Therapies

Researchers have identified many contributing issues leading to the characteristic loss of muscle mass and strength that takes place with age. Arguably the central problems are (a) the disruptions of cell behavior caused by chronic inflammation, (b) damage to neuromuscular junctions, depriving muscle tissue of signals it relies upon for normal maintenance to take place, and (c) loss of muscle stem cell activity, and thus a reduced supply of somatic muscle cells to replace losses. These central problems likely interact with one another, but in principle could be addressed distinctly to produce benefits in patients. Past studies have shown, rather convincingly, that muscle stem cells in older individuals retain their function when moved from an old environment to a young environment. The problem is not […]

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24.03.2026
22:03 News-Medical.Net CREB5 drives stem cell-like transcriptional programs in aggressive prostate cancer

A new research paper was published in Volume 17 of Oncotarget on March 17, 2026, titled "CREB5 regulates stem cell-like transcriptional programs to enhance tumor progression in prostate cancer."

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14.03.2026
12:19 MedicalNewsToday.com Japan becomes first to approve stem cell therapies for Parkinson’s and heart failure

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13.03.2026
05:59 News-Medical.Net ISSCR launches education program on stem cell treatments for Parkinson's

The International Society for Stem Cell Research (ISSCR) today announced the launch of Stem Cell Medicine: Parkinson's Disease, a new continuing education course designed to equip clinicians with an evidence-based understanding of emerging stem cell therapies for Parkinson's disease (PD).

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12.03.2026
12:02 Nanowerk.com Nanogel gives stem cells room to breathe

Nanogel integrated spheroids increase cell retention and repair injured swallowing muscles.

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11.03.2026
21:23 Phys.org Trouble swallowing? A nanogel tweak may keep therapeutic stem cells alive longer

Swallowing is a fundamental human function that supports nutrition and communication. Damage to swallowing muscles can reduce quality of life and even lead to aspiration pneumonia or malnutrition. Many patients suffer from swallowing difficulties after being treated for head or neck cancer, and swallowing disorders are also common in older adults, yet effective therapies have been limited.

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15:39 Nature.Com Author Correction: Gut stem cell necroptosis by genome instability triggers bowel inflammation

Nature is the foremost international weekly scientific journal in the world and is the flagship journal for Nature Portfolio. It publishes the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature publishes landmark papers, award winning news, leading comment and expert opinion on important, topical scientific news and events that enable readers to share the latest discoveries in science and evolve the discussion amongst the global scientific community.

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