Brain, intellect, IQ

Damage to the blood-brain barrier is linked to immune changes and cognitive decline

A pig's brain has been frozen with its cellular activity locked in place and minimal damage. Some believe the same could be done with the brains of people with a terminal illness, so their mind can be reconstructed and they can "continue with their life"

Scientists have found a way to make one of the most aggressive brain tumors vulnerable to the immune system. A single injection of a modified virus can invade glioblastoma, kill cancer cells, and summon immune fighters deep into the tumor. These immune cells persist and attack, which was linked to longer survival in patients.

Tobacco smoking is not associated with functional connectivity alterations in large-scale brain networks among individuals at clinical high risk for psychosis.

Researchers create a new polymer that mimics the mechanical, thermal, and electromagnetic properties of brain tissue, driving new surgical and experimental uses.

A machine-learning analysis of brain waves recorded during sleep may help identify people at high risk of developing dementia, according to a study led by UC San Francisco and Beth Israel Deaconess Medical Center in Boston.

What has long been interpreted as permanent and irreversible vascular damage may not be exclusively so.

People often seem to understand language before they have actually heard enough words to determine its structure. In everyday conversation, listeners react immediately, anticipate what others will say, and rarely wait for a sentence to finish. This raises the question of how the brain is able to keep up with such rapid communication.

Siemens Healthineers announced today its offerings for brain health research are expanding, with the brain-derived, fully automated Atellica IM Phosphorylated tau 217 (pTau217) and Atellica IM Brain Derived Tau (BDTau) assays now available for 1.

The neurodegenerative condition chronic traumatic encephalopathy appears to be driven by damage to the blood-brain barrier due to repetitive head injuries, like those that occur in boxing. This suggests that drugs that strengthen this barrier could prevent or slow the condition

One of the symptoms of schizophrenia is difficulty incorporating new information about the world. This can lead patients to struggle with making decisions and, eventually, to lose touch with reality.

Your morning coffee or tea could be quietly supporting your brain health. A long-term study found that moderate consumption of caffeinated coffee or tea was linked to an 18% lower risk of dementia and better cognitive performance over time. The benefits appeared strongest at 2–3 cups of coffee or 1–2 cups of tea daily—and even held true for people genetically predisposed to dementia.

When patients undergo general anesthesia, doctors can choose among several drugs. Although each of these drugs acts on neurons in different ways, they all lead to the same result: a disruption of the brain's balance between stability and excitability, according to a new MIT study.

Working memory is a cognitive function that is essential for carrying out everyday activities and temporarily retaining information.

New research indicates that the long-term neurological impact of childhood trauma is not permanently etched onto the brain.

Northwestern Medicine scientists have discovered that specialized immune cells within the glioblastoma tumor metabolize fructose to suppress immune responses and promote tumor growth, reports a study published on March 17 in the Proceedings of the National Academy of Sciences.

A two-drug combination frequently used in anti-aging research causes brain damage in mice, University of Connecticut researchers report in the March 16 issue of PNAS.

The combined Mediterranean and blood pressure lowering diet (MIND) may slow the structural changes related to brain aging, finds research published online in the Journal of Neurology Neurosurgery & Psychiatry.

As they imagine typing, implants translate brain signals into keystrokes on a standard digital keyboard. The post Brain Implants Let Paralyzed People Type Nearly as Fast as Smartphone Users appeared first on SingularityHub.

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Trump's slurred Iran update at Doral has fuelled scrutiny of his health and judgement, as critics and former allies question his fitness to lead.

Researchers have identified a surprising brain pattern that may help explain why people with ADHD often struggle to stay focused. Even while awake, their brains can slip into brief episodes of “sleep-like” activity during demanding tasks. These moments are linked to more mistakes, slower reaction times, and lapses in attention.

The James Webb Space Telescope has revealed new details in a bizarre nebula that looks like a brain floating in space. Formed by a dying star, the “Exposed Cranium” nebula shows layered gas and a dark central divide that creates its eerie shape. Webb’s infrared view suggests powerful jets may be shaping the structure. The images capture a brief and dramatic phase in a star’s final evolution.

Among patients with cancer, brain metastases, and type 2 diabetes, GLP-1 use is associated with lower all-cause mortality, new data suggest.

The aging of the brain is characterized by the formation of solid aggregates of misfolded amyloid-β peptides. This is a foundation for later loss of cognitive function and the development of the more severe, inflammatory dysfunction of late stage Alzheimer's disease. Researchers here provide data from cell studies to suggest that the innate immune cells known as microglia maladaptively manufacture amyloid-β aggregates in the process of attempting to clear amyloid. Microglia have been the target of increasing interest in the context of the aging of the brain and development of neurodegenerative conditions, though much of that has focused on growing inflammation driven by this cell population. It seems we might have to consider that the normal operation of microglia becomes pathological when faced with protein […]

Narrowing the gap between an individual’s biological and chronological age is linked to better brain health and a 23% reduced stroke risk, new research suggests.

MIT neuroscientists have figured out how the brain is able to focus on a single voice among a

Implementing a simple exercise plan during chemotherapy may ease cognitive impairment and fatigue, promoting better health outcomes for cancer patients.

A randomized placebo controlled experiment shows that increasing noradrenaline during learning does not improve basic memory accuracy but increases the spread of associations across the hippocampal cognitive map. This broader neural linking leads to greater overgeneralization errors days later, suggesting that noradrenergic arousal can reshape how related memories become interconnected.

Deciding if and when to pursue deep brain stimulation (DBS) can be overwhelming for people with Parkinson's disease. While DBS is one of the most effective interventions for movement symptoms, it's also among the most complex.

New from JNeurosci, Elaine Pinggal, from Monash University, and colleagues assessed how sleep-like brain activity in awake adults influences sustained attention during a task.

Researchers have identified a distinct and reproducible gene expression program associated with neurotransmission in the living human brain, offering unprecedented insight into the molecular mechanisms that support human cognition, emotion, and behavior.

MIT neuroscientists have figured out how the brain is able to focus on a single voice among a cacophony of many voices, shedding light on a longstanding neuroscientific phenomenon known as the cocktail party problem.

A brain mechanism may explain why approximately 40% of people with hypertension continue to have high blood pressure despite taking medication. The discovery reveals potential targets for new treatments.

A brain-computer interface allowed two people who had lost the ability to move their limbs to type at speeds of up to 22 words per minute

MONDAY, March 16, 2026 — It’s long been known that exercise improves a person’s brain health – and researchers now think they better understand at least one of the factors at play.Just one 15-minute session of aerobic exercise floods the brain with...

MONDAY, March 16, 2026 — Loneliness can impact a woman’s brain health as she begins menopause, a new study says.Loneliness and social isolation are both linked to the cognitive decline a woman feels as she begins to transition into menopause, res...

How can we explain the onset of psychotic symptoms characteristic of schizophrenia? Despite their major and often irreversible impact on intellectual abilities and autonomy, the biological mechanisms that precede their emergence remain poorly understood.

From emergency oil reserves to nuclear scrutiny, bigger hail, and research on a connection between the aging gut and the brain

Researchers found that very small numbers of gut bacteria can translocate to the brain in mice, particularly when gut barrier permeability increases due to a Paigen diet. Evidence suggests the vagus nerve may serve as a partial route for this gut-to-brain microbial movement.

Explore the alleged heated confrontation between Meghan Markle and Prince William, as detailed in Tom Bower's new book, and the Sussexes' response.

‘Cryosleep’ remains the preserve of science fiction, but researchers are getting closer to restoring brain function after deep freezing

Billy Joel's daughter Alexa Ray Joel says the music legend is 'doing great' as he manages a rare brain disorder, offering fans reassurance after concert cancellations.

Whole brain radiotherapy (WBRT) saves lives by treating cancer that has spread to the brain, but it also

A single shot protected mice from the protein gunk implicated in Alzheimer's disease. The post These Genetically Engineered Brain Cells Devour Toxic Alzheimer’s Plaques appeared first on SingularityHub.

Tiny plastic particles may be quietly threatening brain health. New research suggests microplastics—now widely found in food, water, and even household dust—could trigger inflammation and damage in the brain through multiple biological pathways. Scientists estimate adults may consume about 250 grams of these particles each year, and some can accumulate in organs including the brain.

Persons under stress may have a harder time spatially orienting themselves. Researchers in Bochum have discovered why.

A trumpet-shaped, single-celled organism seems able to predict one thing will follow another, hinting that such associative learning emerged long before multicellular nervous systems

FRIDAY, March 13, 2026 — Think you’re great at multitasking? Answering texts, listening to a podcast and finishing work at the same time?Your brain may disagree.A new study out of Germany suggests that people can’t truly do two tasks at once, even a...

Neuracle Technologies’ invasive brain-computer interface has been given the greenlight in China for people with partial spinal cord injuries

FRIDAY, March 13, 2026 — Cancer patients often speak of “chemo brain” – the brain fog that occurs in some while undergoing chemotherapy.A new study suggests that exercise might help thwart chemo brain, helping people with cancer stay mentally sharp...

A trumpet-shaped, single-celled organism seems able to predict one thing will follow another, hinting that such associative learning emerged long before multicellular nervous systems

China's drug regulator said on Friday that it has given the nod for a brain-computer interface system ⁠that helps restore hand-movement ability.

“When there is an attack that kills civilians or doesn’t hit its intended target, people are going to be asking, Oh, was that a human who made that mistake or was that an A.I. system?”

The study ties first-trimester Oropouche infection to severe fetal neurodevelopmental anomalies and urges RT-PCR within 2-7 days plus multiplex arbovirus testing to rule out co-infection.

Lauren Macpherson was travelling home from a festival in London when her life changed forever.

Mel Schilling, 'Married At First Sight' star, shares a heartbreaking update on her cancer spreading to her brain and lungs. Despite limited options, she stays resilient and focused on family.

Iconeus, a French neuroimaging company developing functional ultrasound (fUS) solutions for real-time brain activity imaging, today announced the creation of its U.S. entity, Iconeus Inc. – a key milestone in supporting the adoption of functional ultrasound in preclinical neuroscience research.

Making a living brain transparent and watching its neurons fire without disturbing their function-sounds like science fiction, doesn't it? Yet the solution may already exist within our own bodies.

A team of researchers at the USC Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC has identified important differences in how early Alzheimer's disease-related brain changes appear across racial and ethnic groups, underscoring the need for more inclusive approaches to studying and diagnosing the disease.

Researchers identified in mice a microbiome–gut–brain pathway in which age-associated changes in gut microbes increase medium-chain fatty acids that impair vagal sensory signaling and hippocampal activity. These interoceptive disruptions weaken memory formation, revealing a microbial mechanism that contributes to cognitive decline during aging.

Marshall University and Marshall Health Network, in collaboration with Intermed Labs (IL), has launched a new medical technology development initiative focused on improving the precision and safety of deep brain stimulation (DBS) procedures.

To better understand aging’s role in neurodegeneration, Salk researchers and their collaborators built an atlas of the aging mouse brain, revealing region- and cell-type–specific changes in DNA methylation, genome organization, and gene activity. The post Brain Atlas Maps Epigenetic Changes Associated with Aging in Mice appeared first on GEN - Genetic Engineering and Biotechnology News.

A research team at Kyushu University has been working on developing a technique that not only visually clears brain tissues, but does so in a way that preserves normal brain dynamics. The post Seeing the Brain in a Different Light appeared first on GEN - Genetic Engineering and Biotechnology News.

With more than 100 million neurons in the digestive tract, the gut is commonly known as the "second brain" in numerous cultures, including ancient Greece, Japan, China and India, linking digestion with physical and mental well-being.

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) belong to a spectrum of neurodegenerative diseases with overlapping symptoms, characterized by muscle wasting, paralysis, dementia, and other serious impairments.

Having a stroke changes the way the brain works, leaving many stroke survivors with difficulties with basic cognitive

THURSDAY, March 12, 2026 — Former college athletes can show signs of concussion-related brain decline as early as five years after graduation, a new study says.Athletes who had three or more concussions during college play had worse scores on tests...

Wearable sensors combined with AI offer a novel approach to continuous monitoring of cognitive and emotional health, detecting early changes in brain function.

Scientists have developed a promising new approach to treating Alzheimer’s disease by turning ordinary brain cells into powerful plaque-clearing machines. Instead of requiring frequent antibody infusions like current therapies, the experimental treatment uses genetically engineered astrocytes — abundant support cells in the brain — that are equipped with a CAR “homing device” similar to those used in cancer immunotherapy.

Researchers have discovered a surprising change in how cells produce energy in people with depression. Brain and blood cells in young adults with major depressive disorder produced more energy molecules at rest but had trouble increasing energy production when needed. Scientists believe this imbalance may contribute to symptoms such as fatigue and low motivation. The finding could help pave the way for earlier diagnosis and more personalized treatments.

When Annie Goettemoeller first started working on Alzheimer’s, many of her colleagues were focused on the buildup of amyloid and

New research published in Nature finds that tumor cells within supratentorial ependymomas (SE) – an aggressive childhood brain cancer – cluster into distinct tumor cell populations. Much like a neighborhood in your hometown, each cell subtype within these "communities" has a specific (and previously unappreciated) role to play.

Published in The Lancet Neurology, a new review from the University of Colorado Anschutz in collaboration with UT Southwestern Medical Center, offers the latest scientific explanations for why ketogenic diets reduce seizures in people with epilepsy.

A prospective multicenter study reports that Woven EndoBridge intrasaccular therapy safely and effectively treats unruptured wide-necked bifurcation aneurysms, one of the most challenging brain aneurysm types to manage.

A communication pathway between the brain and the gut may be integral to how well the brain holds on to memories

WEDNESDAY, March 11, 2026 — The U.S. Food and Drug Administration (FDA) has approved a generic drug for a very rare brain disorder, but said it should not be considered a treatment for autism. On Tuesday, the agency cleared leucovorin for...

Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to Parkinson's to ALS and beyond, is expected to double every 20 years.

WEDNESDAY, March 11, 2026 — A researcher is disputing a recent high-profile study claiming that people who live in multilingual countries show healthier brain aging.The study, published in Nature Aging last year, found that knowing more than one l...

WEDNESDAY, March 11, 2026 — The U.S. Food and Drug Administration (FDA) has approved a generic drug for a very rare brain disorder, but said it should not be considered a treatment for autism.On Tuesday, the agency cleared leucovorin for people w...

Donald Trump's recent slurred speech and spiritual doubts spark speculation about his mental state and his remaining years, drawing sharp criticism from former allies.

Cortical Labs is building two data centres that will house its neuron-filled chips. The technology is still in the very early stages of development

Motor imagery (MI) is the mental process of imagining a specific limb movement, such as raising a hand or walking, without physically performing it. These imagined movements generate distinct patterns of brain activity that can be recorded using electroencephalography (EEG).

Researchers argue that exposure to fine particulate air pollution (PM2.5) may affect cognitive function and intelligence, potentially causing large population-level losses in global IQ. Using modelling based on published exposure–response data, the authors estimate that pollution could be associated with tens of billions of IQ points lost worldwide, with the largest impacts in lower-income regions.

Cortical Labs is building two data centres that will house its neuron-filled chips. The technology is still in the very early stages of development

Can smartphones or smartwatches help detect early signs of neurological or mental illness? Researchers at the University of Geneva (UNIGE) monitored a group of participants wearing connected devices, and used artificial intelligence to analyze data such as heart rate, physical activity, sleep and air pollution.

Technology created at The University of Queensland could improve the odds of surviving brain cancer and change how

Cortical Labs says its working on two biological data centers.

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Your brain can spot AI voices even when you can't. New research shows neural activity picks up deepfake tells that your conscious mind misses completely. The post Your brain can spot AI voices even when you can’t appeared first on Digital Trends.

Microsoft just ‘married’ Anthropic’s brain to its enterprise muscle — and the offspring is called Copilot Cowork. Key

Scotland has approved the targeted therapy vorasidenib for some low-grade brain tumours, while NICE in England continues to review its cost-effectiveness.

Jada West, a 12‑year‑old Mason Creek Middle School student in Douglas County, Georgia, died from a brain injury after an after‑school fight that began on a school bus.

Increasing our level of physical fitness leads to a bigger release of brain-boosting proteins following one session of exercise, a new study led by a UCL researcher has found.