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Delivery of therapeutic genes is essential for gene therapy. Adeno-associated viruses (AAVs) are a prime vector for carrying gene cargoes because of their superior gene segmentation flexibility and robust gene reconstitution efficiency. However, their limited packaging capacity is a major challenge for large gene transduction.

In recent years, the field of reproductive health has witnessed significant advancements driven by innovative research methodologies and groundbreaking therapeutic strategies. One of the most pressing concerns facing women today is premature ovarian insufficiency (POI), a condition that can lead to infertility and various hormonal imbalances. Recent studies, including one conducted by Shao et al., […]

Autophagy is the name given to a complex collection of processes responsible for identifying and recycling damaged or otherwise unwanted structures in the cell. Typically, a structure flagged for recycling is engulfed by an autophagosome, which is transported to and fuses with a lysosome, and the structure is broken down inside the lysosome by enzymes. An optimal level of autophagy for the maintenance of cell function only occurs in response to stress, including heat, cold, lack of nutrients, toxins, oxidative damage to important molecules, and so forth. Thus mild stresses that inflict relatively little damage to a cell can improve the function of cells, tissues, and organs, leading to a greater resistance to the damage and dysfunction of aging. Most of the well studied interventions […]

Fitbit founders launch AI platform to help families monitor their health  TechCrunchFrom the Founders of Fitbit: Introducing Luffu, Your Guardian for Family Health & Safety  PR NewswireFitbit's founders push AI into family caregiving  AxiosFitbit’s founders launch a new platform for monitoring your entire family’s health  The VergeFitbit creators launch ‘Luffu,’ a new app for family health sharing  9to5Mac

Fitbit founders launch AI platform to help families monitor their health  TechCrunchFrom the Founders of Fitbit: Introducing Luffu, Your Guardian for Family Health & Safety  PR NewswireFitbit's founders push AI into family caregiving  AxiosFitbit’s founders launch a new platform for monitoring your entire family’s health  The VergeFitbit creators launch ‘Luffu,’ a new app for family health sharing  9to5Mac

In the realm of organ transplantation, the integration of pharmacogenomics into clinical practice has emerged as a transformative approach that holds the potential to significantly enhance patient outcomes. The recent literature, particularly a review by researchers K.D. Belfield, E.A. Cohen, and G. Girone, sheds light on the profound implications of pharmacogenomics in transplantation. This exciting […]

This AI doctor is licensed in all 50 states, the startup says. The deal was led by CRV and Kleiner Perkins.

A new study offers hope that kidney transplant patients could one day have a monthly treatment instead of multiple pills every day.

Collaboration advances Syngenta’s sustainability goal to grow 85% of seed production using regenerative practices by 2030. The post Syngenta, Ducks Unlimited Expand Collaboration to Scale Regenerative Ag in Seed Production Across the Midwest appeared first on CropLife.

AccurEdit Therapeutics, a startup based in Suzhou, China, has raised $75 million in Series A funding to advance its growing pipeline of CRISPR-based medicines — among the largest rounds on record for a Chinese gene editing ...

Luffu uses AI in the background to gather and organize family information, learn day-to-day patterns, and flag notable changes so families can stay aligned and address potential wellbeing issues.

A groundbreaking study has presented a transformative approach to managing kidney transplantation, raising hopes for a future where patients can replace their daily regimen of multiple immunosuppressant pills with monthly infusions. This innovation aims not only to simplify treatment adherence but also to mitigate the damaging side effects often associated with standard therapies and to […]

Recent advancements in medical technology have ushered in a new era for organ transplantation, particularly in kidney transplants. As the world grapples with organ shortages, the demand for effective and non-invasive ways to monitor transplant health has skyrocketed. A recent comprehensive review titled “Non-Invasive Biomarkers for Kidney Transplant Monitoring,” authored by Damas, Caeiro, Ramirez-Bajo, and […]

A large global genetics study shows that many key drivers of Type 2 diabetes operate outside the bloodstream. Scientists are getting a clearer picture of why Type 2 diabetes is so hard to pin down. In a major international project led in part by the University of Massachusetts Amherst and Helmholtz Munich in Germany, researchers [...]

In the rapidly evolving landscape of pharmaceuticals, a groundbreaking study has emerged that underscores the transformative power of artificial intelligence (AI) in the realms of drug discovery and commercialization. Conducted by a collaborative team of researchers including Pipada, Bikkina, and Joshi, the study posits that AI technologies can significantly reduce the time and resources traditionally […]

Scientists at Université de Montréal and its affiliated Centre de recherche Azrieli du CHU Sainte-Justine have made a major advance in their research into cardiovascular disease: They've created functional, three-dimensional heart tissue that can beat autonomously in vitro. The tissue incorporates micro-sensors that make it possible to do finely tuned, real-time analysis of its contractile properties. This advance marks an important step forward for modeling human cardiac diseases and conducting preclinical drug testing.

A new study offers hope that kidney transplant patients could one day have a monthly treatment instead of multiple pills every day. The new treatment may also reduce side effects and increase the lifespan of the donor organ. The results appear in the American Journal of Transplantation.

McCain has announced plans to establish a new UK Farm of the Future in North Yorkshire, aimed at testing regenerative farming practices in r...

The TikToker tells You, Me and the Big C podcast about her cancer journey.

Ultragenyx outlined new data on Tuesday that it hopes will convince the FDA to approve its recently resubmitted rare disease gene therapy. Among 17 patients with Sanfilippo syndrome type A who received the therapy, cognition ...

Medical artificial intelligence is a hugely appealing concept. In theory, models can analyze vast amounts of information, recognize subtle patterns in data, and are never too tired or busy to provide a response. However, although thousands of these models have been and continue to be developed in academia and industry, very few of them have successfully transitioned into real-world clinical settings.

Medical artificial intelligence is a hugely appealing concept. In theory, models can analyze vast amounts of information, recognize subtle patterns in data, and are never too tired or busy to provide a response.

Medical artificial intelligence (AI) is rapidly evolving from a theoretical construct into a tangible instrument that has the potential to revolutionize healthcare. The allure of AI in medicine lies in its capacity to sift through enormous data sets, uncover nuanced patterns, and provide precise recommendations without fatigue or bias. However, despite the substantial investment in […]

Hazırda Azərbaycanda mindən çox şəxsin orqana ehtiyacı var. Bunu Orqan Donorluğu va Transplantasiyası üzrə Koordinasiya Mərkəzinin sədri Yeganə Abbasova jurnalistlərə açıqlamasında deyib. Sədr qeyd edib ki, həmin şəxslərin donor ola biləcək insanlara ehtiyacı var: "Hazırda Azərbaycanda 4642 şəxs dialezdədir.

Inside a cancer research laboratory on the campus of Harvard Medical School, two dozen small jars with pink plastic lids sat on a metal counter. Inside these humble-looking jars is the core of Joan Brugge's current multiyear research project.

С помощью ИИ ученые разработали новый способ настройки ферментов, чтобы они могли редактировать намного больше участков генома, чем это было возможно до сих пор. Результаты открывают возможности для лечения сложных заболеваний, на которые ранее не удавалось воздействовать с помощью CRISPR/Cas9.

The Denise Coates Foundation has donated £12m towards robotic surgery capabilities at the hospital.

An external system may be a lifesaver for patients with no other options.

In a groundbreaking development that challenges longstanding paradigms of cellular aging, a recent study unveils a remarkable mechanism by which embryonic stem cells (ESCs) maintain their youthful vigor and immortality across infinite cell divisions. Published in Cell Research, the study conducted by Wang, Fu, Sun, and colleagues dissects the enigmatic process that allows ESC lineages […]

arXiv:2602.01347v1 Announce Type: new Abstract: Millions of users turn to consumer AI chatbots to discuss behavioral and mental health concerns. While this presents unprecedented opportunities to deliver population-level support, it also highlights an urgent need to develop rigorous and scalable safety evaluations. Here we introduce SIM-VAIL, an AI chatbot auditing framework that captures how harmful AI chatbot responses manifest across a range of mental-health contexts. SIM-VAIL pairs a simulated human user, harboring a distinct psychiatric vulnerability and conversational intent, with an audited frontier AI chatbot. It scores conversation turns on 13 clinically relevant risk dimensions, enabling context-dependent, temporally resolved assessment of mental-health risk. Across 810 conversations, encompassing over 90,000 turn-level ratings and 30 psychiatric user profiles, we find that significant risk occurs across virtually all user phenotypes. Risk manifested across most of the 9

arXiv:2602.00146v1 Announce Type: new Abstract: Scaffolds have a key role in the clinical success of tissue engineering for the regeneration of damaged tissues. Their bio-performance is often described as the extent to which they can provide an extracellular matrix-like environment for cells embedded where their function and growth can effectively continue. For this purpose, tissue engineering scaffolds should exhibit biodegradability, biocompatibility, bioactivity, delivery, and mechanical performance. The use of polymer coatings, especially poly(lactic-co-glycolic acid) (PLGA), on tissue engineering scaffolds has been found to be one of the most effective methods to improve the scaffold properties. This paper reviews the techniques used to coat tissue engineering scaffolds with PLGA and its effects on the mechanical characteristics, biodegradability, biocompatibility, Molecular delivery, and osteointegration of the scaffolds. It is concluded that apart from apatite-formation

arXiv:2602.01347v1 Announce Type: cross Abstract: Millions of users turn to consumer AI chatbots to discuss behavioral and mental health concerns. While this presents unprecedented opportunities to deliver population-level support, it also highlights an urgent need to develop rigorous and scalable safety evaluations. Here we introduce SIM-VAIL, an AI chatbot auditing framework that captures how harmful AI chatbot responses manifest across a range of mental-health contexts. SIM-VAIL pairs a simulated human user, harboring a distinct psychiatric vulnerability and conversational intent, with an audited frontier AI chatbot. It scores conversation turns on 13 clinically relevant risk dimensions, enabling context-dependent, temporally resolved assessment of mental-health risk. Across 810 conversations, encompassing over 90,000 turn-level ratings and 30 psychiatric user profiles, we find that significant risk occurs across virtually all user phenotypes. Risk manifested across most of the 9

arXiv:2602.02475v1 Announce Type: new Abstract: AI agents often fail in ways that are difficult to localize because executions are probabilistic, long-horizon, multi-agent, and mediated by noisy tool outputs. We address this gap by manually annotating failed agent runs and release a novel benchmark of 115 failed trajectories spanning structured API workflows, incident management, and open-ended web/file tasks. Each trajectory is annotated with a critical failure step and a category from a grounded-theory derived, cross-domain failure taxonomy. To mitigate the human cost of failure attribution, we present AGENTRX, an automated domain-agnostic diagnostic framework that pinpoints the critical failure step in a failed agent trajectory. It synthesizes constraints, evaluates them step-by-step, and produces an auditable validation log of constraint violations with associated evidence; an LLM-based judge uses this log to localize the critical step and category. Our framework improves step

arXiv:2602.01515v1 Announce Type: new Abstract: Deploying learned control policies on humanoid robots is challenging: policies that appear robust in simulation can execute confidently in out-of-distribution (OOD) states after Sim-to-Real transfer, leading to silent failures that risk hardware damage. Although anomaly detection can mitigate these failures, prior methods are often incompatible with high-rate control, poorly calibrated at the extremely low false-positive rates required for practical deployment, or operate as black boxes that provide a binary stop signal without explaining why the robot drifted from nominal behavior. We present RAPT, a lightweight, self-supervised deployment-time monitor for 50Hz humanoid control. RAPT learns a probabilistic spatio-temporal manifold of nominal execution from simulation and evaluates execution-time predictive deviation as a calibrated, per-dimension signal. This yields (i) reliable online OOD detection under strict false-positive

arXiv:2602.01086v1 Announce Type: new Abstract: Background: As of 2026, Large Language Models (LLMs) demonstrate expert-level medical knowledge. However, deploying them as autonomous "Clinical Agents" remains limited. Current Electronic Medical Records (EMRs) and standards like FHIR are designed for human review, creating a "Context Mismatch": AI agents receive fragmented data and must rely on probabilistic inference (e.g., RAG) to reconstruct patient history. This approach causes hallucinations and hinders auditability. Methods: We propose MedBeads, an agent-native data infrastructure where clinical events are immutable "Beads"--nodes in a Merkle Directed Acyclic Graph (DAG)--cryptographically referencing causal predecessors. This "write-once, read-many" architecture makes tampering mathematically detectable. We implemented a prototype with a Go Core Engine, Python middleware for LLM integration, and a React-based visualization interface. Results: We successfully implemented the

arXiv:2602.00910v1 Announce Type: new Abstract: Deep learning has revolutionized medical image analysis, playing a vital role in modern clinical applications. However, the deployment of large-scale models in real-world clinical settings remains challenging due to high computational costs, latency constraints, and patient data privacy concerns associated with cloud-based processing. To address these bottlenecks, this review provides a comprehensive synthesis of efficient and lightweight deep learning architectures specifically tailored for the medical domain. We categorize the landscape of modern efficient models into three primary streams: Convolutional Neural Networks (CNNs), Lightweight Transformers, and emerging Linear Complexity Models. Furthermore, we examine key model compression strategies (including pruning, quantization, knowledge distillation, and low-rank factorization) and evaluate their efficacy in maintaining diagnostic performance while reducing hardware requirements.

Treatment-naive patients with metastatic renal cell carcinoma receive encapsulated fecal microbiota transplants with immunotherapy.

A University of Missouri researcher is pioneering an innovative solution to remove tiny bits of plastic pollution from our water. Mizzou's Susie Dai recently applied a revolutionary strain of algae toward capturing and removing harmful microplastics from polluted water. Driven by a mission to improve the world for both wildlife and humans, Dai also aims to repurpose the collected microplastics into safe, bioplastic products such as composite plastic films.

In today's open access paper, researchers review the evidence for exercise to slow the aging of muscle tissue in part because it improves DNA repair mechanisms. How exactly damage to nuclear DNA contributes to aging beyond creating a raised risk of cancer remains a debated topic, despite recent conceptual advances. Nuclear DNA damage occurs constantly, near all of which is repaired. Yet the remaining damage largely occurs in genes that are not used or that are not all that important, and in cells with few replications remaining. Thus the ability to cause harmful alterations to cellular metabolism throughout a tissue was thought to be limited. The first way in which nuclear DNA damage could meaningfully impact aging is via somatic mosaicism. When mutations occur in […]

Your organs are constantly talking to each other in ways we’re only beginning to understand. Tapping into these communication networks is opening up radical new ways to boost health

The most robust evidence to date shows that people with a type of lung cancer lived longer if they received immunotherapy before 3pm

In the world of organ transplantation, the criteria for selecting candidates have always been complex and multifaceted. As lung transplantation, in particular, has gained prominence due to advances in medical science, there remains ongoing debate among medical professionals regarding a pivotal question: how critical is too critical when considering patients for lung transplantation? A recent […]

Researchers from The Ohio State University and the Indian Institute of Technology Madras have developed an artificial intelligence framework to rapidly generate drug-like molecules that are easier to synthesize in real-world laboratory settings. The new system, called PURE (Policy-guided Unbiased REpresentations for Structure-Constrained Molecular Generation), promises to significantly cut down the early-stage timelines of drug development—currently a billion-dollar, decade-long process—and could play a crucial role in addressing drug resistance in cancer and infectious diseases. It stands apart from existing molecule-generation AI tools that rely on rigid scoring mechanisms or statistical optimization.

At last week’s HITLAB January 2026 Symposium, Matthew Holt gave a talk about what’s wrong with primary care, how concierge care for all can fix it, and how the most advanced primaryContinue reading...

In the relentless pursuit of understanding aging and its intricate relationship with chronic diseases, a groundbreaking discovery has emerged from the laboratories at Vanderbilt University. The research, led by Assistant Professor Kris Burkewitz and published in Nature Cell Biology in February 2026, unveils a novel mechanism by which cells actively remodel their internal architecture during […]

Apis Capital Advisors’ Apis Flagship Fund released its Q4 2025 investor letter. A copy of the letter can be downloaded here. Apis Flagship Fund delivered strong performance in the fourth quarter of 2025, with the Fund up 10.0% net for the quarter and gaining 55.1% for the full year, significantly outperforming the MSCI ACWI global […]

The NHS has launched an AI and robot pilot to help spot lung cancer sooner, as well as a screening program that aims to help tackle inequalities in cancer.

A UK Biobank suggests hormone replacement therapy may offer only limited protection for mental health and cognition in menopausal women.

In a groundbreaking advancement poised to redefine the landscape of genome editing, researchers have unveiled a sophisticated deep learning framework capable of transforming the targeting specificities of CRISPR–Cas enzymes. At the heart of this innovation lies the ability to customize the protospacer-adjacent motif (PAM) recognition of Cas proteins, a critical determinant that traditionally restricts the […]

Biotechnology in 2026 – Gene Editing and More As we dive into 2026, where AI and Automation already achieving an upper hand, biotech finds its way. There are a number of technologies that made news last year, for good as well as for bad. Three technologies are going to be life-changing and require attention, say […] The post Gene Editing and Other Key Technologies Shaping Biotechnology in 2026 appeared first on BioTecNika.

Researchers have been publishing more data of late from the CALERIE trial of human calorie restriction that took place over the course of a few years. The participants aimed at a 25% reduction in calorie intake, and ended up achieving something more like 12-15%. The trial started nearly 20 years ago at this point. It is often the case that tissue samples and data remain intact and potentially useful long after the study is complete, awaiting greater funding and interest, as well as the existence of more advanced analysis technologies. Small non-coding RNAs (smRNAs), approximately 20-35 nucleotides in length, represent a diverse class of regulatory molecules that include microRNAs (miRs) and piwi-interacting RNAs (piRs). These nanoscale molecules are key regulators of gene expression, orchestrating complex […]

Gene-editing citrus fruits to make them less bitter could not only encourage more people to eat them, it might also help save the industry from a devastating plague  

When her doctor died suddenly in August, Tammy MacDonald found herself among the roughly 17% of adults in America without a primary care physician.

arXiv:2601.22192v1 Announce Type: new Abstract: The regeneration of oral and craniofacial bone defects ranging from minor periodontal and peri-implant defects to large and critical lesions imposes a substantial global health burden. Conventional therapies are associated with several limitations, highlighting the development of a unique treatment strategy, such as tissue engineering. A well-designed scaffold for bone tissue engineering should possess biocompatibility, biodegradability, mechanical strength, and osteoconductivity. For this purpose, mesoporous silica nanoparticles (MSNs) were synthesized and incorporated at different ratios (10, 20, and 30%) into alginate/chitosan (Alg/Chit)-based porous composite scaffolds fabricated through the freeze-drying method. The MSN incorporation significantly improved the mechanical strength of the scaffolds while showing a negligible decreasing effect on the porosity. All of the samples showed desirable swelling behaviors, which is beneficial

arXiv:2601.22702v1 Announce Type: new Abstract: Machine learning (ML) in medicine has transitioned from research to concrete applications aimed at supporting several medical purposes like therapy selection, monitoring and treatment. Acceptance and effective adoption by clinicians and patients, as well as regulatory approval, require evidence of trustworthiness. A major factor for the development of trustworthy AI is the quantification of data quality for AI model training and testing. We have recently proposed the METRIC-framework for systematically evaluating the suitability (fit-for-purpose) of data for medical ML for a given task. Here, we operationalize this theoretical framework by introducing a collection of data quality metrics - the metric library - for practically measuring data quality dimensions. For each metric, we provide a metric card with the most important information, including definition, applicability, examples, pitfalls and recommendations, to support the

arXiv:2601.22645v1 Announce Type: new Abstract: Generative medical AI now appears fluent and knowledgeable enough to resemble clinical intelligence, encouraging the belief that scaling will make it safe. But clinical reasoning is not text generation. It is a responsibility-bound process under ambiguity, incomplete evidence, and longitudinal context. Even as benchmark scores rise, generation-centric systems still show behaviours incompatible with clinical deployment: premature closure, unjustified certainty, intent drift, and instability across multi-step decisions. We argue these are structural consequences of treating medicine as next-token prediction. We formalise Clinical Contextual Intelligence (CCI) as a distinct capability class required for real-world clinical use, defined by persistent context awareness, intent preservation, bounded inference, and principled deferral when evidence is insufficient. We introduce Meddollina, a governance-first clinical intelligence system

arXiv:2601.22633v1 Announce Type: new Abstract: The integration of Large Language Models (LLMs) into network operations (AIOps) is hindered by two fundamental challenges: the stochastic grounding problem, where LLMs struggle to reliably parse unstructured, vendor-specific CLI output, and the security gap of granting autonomous agents shell access. This paper introduces MCP-Diag, a hybrid neuro-symbolic architecture built upon the Model Context Protocol (MCP). We propose a deterministic translation layer that converts raw stdout from canonical utilities (dig, ping, traceroute) into rigorous JSON schemas before AI ingestion. We further introduce a mandatory "Elicitation Loop" that enforces Human-in-the-Loop (HITL) authorization at the protocol level. Our preliminary evaluation demonstrates that MCP-Diag achieving 100% entity extraction accuracy with less than 0.9% execution latency overhead and 3.7x increase in context token usage.

Recent findings in the field of cancer research have shed light on the intricate relationship between the immune system and tumor progression, particularly concerning a type of immune cell known as macrophages. A groundbreaking study conducted by Zhang et al. has delved into how senescent CXCL16^+ macrophages significantly influence the trajectory of lung adenocarcinoma, a […]

In an innovative leap that blends technology and healthcare, the development of the Sarcopenia Artificial Intelligence Diagnostic Decision Support System (SAID DSS) marks a transformative approach to diagnosing sarcopenia, a condition primarily affecting the elderly population characterized by the progressive loss of skeletal muscle mass and strength. As global demographics shift, with populations aging at […]

The key statistics and numbers behind Carlos Alcaraz's historic Australian Open victory.

The University of Ottawa has made a groundbreaking stride by establishing the Ottawa Medical Artificial Intelligence Research Institute (OMARI), positioning itself at the forefront of medical AI research, education, and innovation. This state-of-the-art institute, led by Dr. Khaled El Emam, who holds the position of Canada Research Chair in Medical Artificial Intelligence, strives to foster […]

Elon Musk told Davos ageing is 'very solvable' and life extension 'highly likely' but cautioned immortality could create rigid, stagnant societies lacking vibrancy.

U.S. health officials unveiled proposed changes to the nation's transplant system, hoping to help more patients get lifesaving organs, even when donations aren't perfect.

In the realm of advanced therapeutic techniques, lentiviral vectors have emerged as transformative agents in the realm of viral gene therapy. Their capacity to efficiently deliver genetic material into host cells has made them a subject of intense research and innovation. Notably, a groundbreaking study conducted by Kaiser, Rouchka, and Smith has explored the adaptation […]

What determines how long we live—and to what extent is our lifespan shaped by our genes? Surprisingly, for decades, scientists believed that the heritability of human lifespan was relatively low compared to other human traits, standing at just 20–25%; some recent large-scale studies even placed it below 10%.

Tempus AI, Inc. (NASDAQ:TEM) is one of the best Nancy Pelosi Stocks to buy in 2026. On January 27, Tempus AI, Inc. (NASDAQ:TEM) confirmed that its Immune Profile Score Test accurately predicts patient outcomes for immune checkpoint inhibitor therapy, compared with conventional biomarkers. Consequently, it continues to demonstrate superior predictive accuracy, with a hazard ratio […]

Nicole Fan / Rest of World: Chinese government funding is backing traditional Chinese medicine providers to adopt AI for drug discovery, clinical diagnostics, acupuncture robots, and more  —  With backing from the Chinese government, TCM practitioners are integrating AI tools to reach new consumers at home and abroad.

In recent years, the integration of artificial intelligence in various sectors has sparked considerable interest, and the field of healthcare, particularly nursing education, is no exception. The implications of generative AI in enhancing nursing diagnostic reasoning present unprecedented opportunities for transformation within classroom settings. With the ongoing advancements in AI, educators are exploring innovative methods […]

A research team led by Prof. Dr. Christian Hinze, senior physician at the MHH Clinic for Kidney and Hypertension Diseases at Hannover Medical School (MHH), has gained new insights into the treatment of kidney transplant patients. The team has discovered properties of kidney cells that, after rejection, provide information about how well a transplant will recover in the long term.

Aging muscles heal more slowly after injury—a frustrating reality familiar to many older adults. A UCLA study conducted in mice reveals an unexpected cause: Stem cells in aged muscle accumulate higher levels of a protein that slows their ability to activate and repair tissue, but helps the cells survive longer in the harsh environment of aging tissue.

Brock E.W. Turner / Axios: Miami-based Indigo, which uses AI-powered underwriting tech to provide medical liability insurance to physicians, raised a $50M Series B led by Rubicon Founders  —  Indigo, which provides liability insurance to physicians, raised $50 million in a Series B funding round, CEO Jared Kaplan tells Axios Pro exclusively.

Eli Lilly and Company (NYSE:LLY) is included among the 12 Best Stocks to Buy for the Long Term. According to a report by Reuters, Eli Lilly and Company (NYSE:LLY) has signed an agreement worth up to $1.12 billion with Seamless Therapeutics. The Germany-based startup announced the deal on January 28. The partnership focuses on developing […]

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In a groundbreaking study published in Molecular Cancer, researchers explored the role of CircKIAA1617 in the context of estrogen receptor-positive (ER-positive) breast cancer, a prevalent subtype that often poses therapeutic challenges. The team, led by esteemed scientists Yang, Li, and Wang, sought to understand how the circular RNA CircKIAA1617 influences cancer stemness, a concept crucial […]

Duke Nukem 3D smashed the 3D FPS Doom clone mold in 1996.

Jan. 31, 2026: Our weekly roundup of the latest science in the news, as well as a few fascinating articles to keep you entertained over the weekend.

An analysis of twin cohort data suggests that human life span is far more heritable than previously believed.

Canlı donor orqanlarından transplantasiya Azərbaycanda əvvəllər də həyata keçirilirdi. Lakin ürək kimi tək və həyati vacib orqanların transplantasiyası yalnız beyin ölümü baş vermiş donorlardan, yəni meyit (kadvavra) donorlarından mümkün olur.

Azərbaycan Respublikasının Səhiyyə Nazirliyi və Azərbaycan Ürək və Damar Cərrahiyyəsi Cəmiyyətinin birgə təşkilatçılığı ilə "Qafqazda ilk ürək transplantasiyası: Azərbaycan səhiyyəsinin tarixi nailiyyəti və gələcək perspektivlər" mövzusunda dəyirmi masa keçirilir.

Ürək transplantasiya əməliyyatının Qafqazda ilk Azərbaycanda icra olunması üçün uzun yol qət edildi.

Viola Zhou / Rest of World: Ant Group reports 30M MAUs for its AI health chatbot Ant Afu, which integrates appointments, test analysis, and insurance payments within Alipay's ecosystem  —  Ant's health chatbot has become a top downloaded app in China as users seek personalized care they can't get from the overburdened hospitals.

Microbiologist John van der Oost of Wageningen University & Research (WUR) has received an ERC Proof of Concept grant to further develop a promising CRISPR-based approach to cancer treatment. With funding of €150,000, he and researcher Christian Südfeld will spend the next eighteen months working on a method to kill cancer cells from within, while sparing healthy cells as much as possible.

As the global population ages, the quest for longevity and improved quality of life in later years becomes ever more pertinent. Recent research has highlighted the complex relationship between diet and longevity, particularly in the fascinating case of centenarians—individuals who reach the remarkable age of 100 years or more. In a groundbreaking study conducted by […]

FRIDAY, Jan. 30, 2026 — U.S. health officials unveiled proposed changes to the nation’s transplant system, hoping to help more patients get lifesaving organs, even when donations aren’t perfect.The Centers for Medicare and Medicaid Services (CMS) sa...

In recent years, the evolution of artificial intelligence (AI) has made significant inroads in various fields, including healthcare. One area that has captured the attention of researchers and medical professionals alike is dermatology, particularly in the realm of dermoscopic image analysis. As skin diseases continue to pose diagnostic challenges, leveraging sophisticated AI algorithms promises enhanced […]

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In a groundbreaking new study, researchers have unveiled the remarkable potential of mesenchymal stem cells (MSCs) to alleviate the deadly severity of cerebral malaria, a neurological complication that remains a lethal challenge in malaria-endemic regions worldwide. The study, published in the journal Cell Death Discovery, dives deep into the immunological mechanisms underpinning cerebral malaria and […]

Ultragenyx has resubmitted its approval request for a rare disease gene therapy after the FDA rejected it last summer. UX111 is an AAV gene therapy designed to treat Sanfilippo syndrome type A. The company is ...

Ssome molecular changes associated with getting older may actually be protective adaptations. Continue reading Muscle stem cells become more resistant but less restorative over time on Tech Explorist.

Types of dose-related adverse drug reactionsThe Law of Mass action predicts that all adverse drug reactions are related to the concentration of the drug at the site of action, and therefore to the administered dose.1 In other words, there is no such thing as a non-dose-related adverse drug reaction.According to the DoTS (dose, time, susceptibility) classification of adverse drug reactions (ADRs), there are three types of adverse drug reactions in relation to the dose or concentration of the drug with which the reaction is associated2:• hypersusceptibility reactions: these are reactions that occur at doses or concentrations that are lower than those usually associated with therapeutic benefit; all allergic reactions come under this heading, plus a few reactions that are not allergic but occur at low concentrations, such as angioedema associated with ACE inhibitors;• collateral reactions: these are associated with doses or concentrations that are within the same range as those...

Aging muscles heal more slowly after injury - a frustrating reality familiar to many older adults.