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31.03.2026
10:24 Arxiv.org Math Estimating an initial telomere length distribution from the Laplace transform of its senescence times distribution

arXiv:2603.27875v1 Announce Type: new Abstract: This work follows from a previous study on the estimation of an initial distribution of telomere length from a senescence times distribution done in [10.1051/m2an/2026022, J. Olay{\'e}]. In this previous study, we have presented an estimation method based on the fact that our telomere shortening model can be approximated by a transport equation. This method has encouraging results, but fails to provide a good estimation when the variability of the initial telomere length distribution is too small. We improve here this method by approximating our model with an advection-diffusion equation, which allows us to better take into account the randomness of the shortening values. We show that under this approximation, there exists a simple link between the Laplace transform of the initial telomere length distribution and that of the senescence times distribution. Then, by using a numerical method for inverting Laplace transforms called

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10:09 Arxiv.org CS Towards a Medical AI Scientist

arXiv:2603.28589v1 Announce Type: new Abstract: Autonomous systems that generate scientific hypotheses, conduct experiments, and draft manuscripts have recently emerged as a promising paradigm for accelerating discovery. However, existing AI Scientists remain largely domain-agnostic, limiting their applicability to clinical medicine, where research is required to be grounded in medical evidence with specialized data modalities. In this work, we introduce Medical AI Scientist, the first autonomous research framework tailored to clinical autonomous research. It enables clinically grounded ideation by transforming extensively surveyed literature into actionable evidence through clinician-engineer co-reasoning mechanism, which improves the traceability of generated research ideas. It further facilitates evidence-grounded manuscript drafting guided by structured medical compositional conventions and ethical policies. The framework operates under 3 research modes, namely paper-based

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10:09 Arxiv.org CS Measuring Cross-Jurisdictional Transfer of Medical Device Risk Concepts with Explainable AI

arXiv:2603.28540v1 Announce Type: new Abstract: Medical device regulators in the United States(FDA), China (NMPA), and Europe (EU MDR) all use the language of risk, but classify devices through structurally different mechanisms. Whether these apparently shared concepts carry transferable classificatory signal across jurisdictions remains unclear. We test this by reframing explainable AI as an empirical probe of cross-jurisdictional regulatory overlap. Using 141,942 device records, we derive seven EU MDR risk factors, including implantability, invasiveness, and duration of use, and evaluate their contribution across a three-by-three transfer matrix. Under a symmetric extraction pipeline designed to remove jurisdiction-specific advantages, factor contribution is negligible in all jurisdictions, indicating that clean cross-jurisdictional signal is at most marginal. Under jurisdiction specific pipelines, a modest gain appears only in the EU MDR-to-NMPA direction, but sensitivity analyses

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10:09 Arxiv.org CS Physics-Embedded Feature Learning for AI in Medical Imaging

arXiv:2603.28057v1 Announce Type: new Abstract: Deep learning (DL) models have achieved strong performance in an intelligence healthcare setting, yet most existing approaches operate as black boxes and ignore the physical processes that govern tumor growth, limiting interpretability, robustness, and clinical trust. To address this limitation, we propose PhysNet, a physics-embedded DL framework that integrates tumor growth dynamics directly into the feature learning process of a convolutional neural network (CNN). Unlike conventional physics-informed methods that impose physical constraints only at the output level, PhysNet embeds a reaction diffusion model of tumor growth within intermediate feature representations of a ResNet backbone. The architecture jointly performs multi-class tumor classification while learning a latent tumor density field, its temporal evolution, and biologically meaningful physical parameters, including tumor diffusion and growth rates, through end-to-end

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10:09 Arxiv.org CS Filipino Students' Willingness to Use AI for Mental Health Support: A Path Analysis of Behavioral, Emotional, and Contextual Factors

arXiv:2603.27994v1 Announce Type: new Abstract: This study examined how behavioral, emotional, and contextual factors influence Filipino students' willingness to use artificial intelligence (AI) for mental health support. Results showed that habit had the strongest effect on willingness, followed by comfort, emotional benefit, facilitating conditions, and perceived usefulness. Students who used AI tools regularly felt more confident and open to relying on them for emotional support. Empathy, privacy, and accessibility also increased comfort and trust in AI systems. The findings highlight that emotional safety and routine use are essential in promoting willingness. The study recommends AI literacy programs, empathic design, and ethical policies that support responsible and culturally sensitive use of AI for student mental health care.

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10:09 Arxiv.org CS MEDIC-AD: Towards Medical Vision-Language Model's Clinical Intelligence

arXiv:2603.27176v1 Announce Type: new Abstract: Lesion detection, symptom tracking, and visual explainability are central to real-world medical image analysis, yet current medical Vision-Language Models (VLMs) still lack mechanisms that translate their broad knowledge into clinically actionable outputs. To bridge this gap, we present MEDIC-AD, a clinically oriented VLM that strengthens these three capabilities through a stage-wise framework. First, learnable anomaly-aware tokens ( ) encourage the model to focus on abnormal regions and build more discriminative lesion centered representations. Second, inter image difference tokens ( ) explicitly encode temporal changes between studies, allowing the model to distinguish worsening, improvement, and stability in disease burden. Finally, a dedicated explainability stage trains the model to generate heatmaps that highlight lesion-related regions, offering clear visual evidence that is consistent with the model's reasoning. Through

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10:09 Arxiv.org CS arg-VU: Affordance Reasoning with Physics-Aware 3D Geometry for Visual Understanding in Robotic Surgery

arXiv:2603.26814v1 Announce Type: new Abstract: Affordance reasoning provides a principled link between perception and action, yet remains underexplored in surgical robotics, where tissues are highly deformable, compliant, and dynamically coupled with tool motion. We present arg-VU, a physics-aware affordance reasoning framework that integrates temporally consistent geometry tracking with constraint-induced mechanical modeling for surgical visual understanding. Surgical scenes are reconstructed using 3D Gaussian Splatting (3DGS) and converted into a temporally tracked surface representation. Extended Position-Based Dynamics (XPBD) embeds local deformation constraints and produces representative geometry points (RGPs) whose constraint sensitivities define anisotropic stiffness metrics capturing the local constraint-manifold geometry. Robotic tool poses in SE(3) are incorporated to compute rigidly induced displacements at RGPs, from which we derive two complementary measures: a

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10:09 Arxiv.org CS From Prediction to Diagnosis: Reasoning-Aware AI for Photovoltaic Defect Inspection

arXiv:2603.26776v1 Announce Type: new Abstract: Reliable photovoltaic defect identification is essential for maintaining energy yield, ensuring warranty compliance, and enabling scalable inspection of rapidly expanding solar fleets. Although recent advances in computer vision have improved automated defect detection, most existing systems operate as opaque classifiers that provide limited diagnostic insight for high-stakes energy infrastructure. Here we introduce REVL-PV, a vision-language framework that embeds domain-specific diagnostic reasoning into multimodal learning across electroluminescence, thermal, and visible-light imagery. By requiring the model to link visual evidence to plausible defect mechanisms before classification, the framework produces structured diagnostic reports aligned with professional photovoltaic inspection practice. Evaluated on 1,927 real-world modules spanning eight defect categories, REVL-PV achieves 93\% classification accuracy while producing

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08:33 IbTimes.co.uk Health Care Coverage Is Now Decided by AI—Here's What You Need to Know About Its Role in Insurance

Explore how AI is transforming health insurance in the US, raising legal and ethical questions about patient care and oversight.

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07:58 Medscape.Com Liver Transplant Access Varies by Location, Not Just Need

Patients with severe alcohol-associated hepatitis living in deprived areas are less likely to be referred for a liver transplant when their disease severity is moderate.

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02:21 MedicalXpress.com Researchers use nasal stem cells to help nerves regrow in damaged limbs

Two Northeastern University researchers want to make life better for people who've experienced serious physical trauma, the kind caused by bad car accidents or from injuries sustained during wartime; such procedures are crucial. That process takes on an added layer of complication when damage occurs to the nervous system.

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02:21 MedicalXpress.com Bile acid and steroid signatures tied to extreme longevity

Centenarians often live to 100+ due to a combination of protective genetic factors, which account for up to 50%, and healthy lifestyles, such as plant-forward diets, regular, natural movement and strong social connections. While these "agers" often possess unique immune system signatures, understanding the metabolic signs of healthy aging is not yet fully understood.

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01:45 IbTimes.co.uk Angelina Jolie 'Clone' Rumours Explained: Was Brad Pitt's Ex Replaced by a Body Double at a China Fashion Show?

Angelina Jolie's appearance at a Shanghai Tom Ford event triggered online frenzy over clone and body double claims, fuelling debate on her looks amid longstanding health disclosures.

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30.03.2026
23:46 Phys.org Cyclic catalysts use sunlight and air to regenerate during pharma ingredient synthesis

In chemical processes for producing pharmaceuticals, catalysts are a core technology that determines production speed and cost. However, until now, there has been a trade-off between "precise but disposable catalysts" and "reusable catalysts." A KAIST research team has developed an eco-friendly catalytic technology that combines these two types, operating solely with light and air. This opens a pathway to producing pharmaceutical ingredients more cheaply and cleanly, with expected reductions in carbon emissions and environmental pollution. The study is published in the Journal of the American Chemical Society.

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22:42 MedicalXpress.com Changing the long search for rare disease diagnoses with new AI breakthrough

A newly developed AI tool can dramatically speed up the search for the genetic causes of rare diseases, a process that often takes years and frequently ends without answers. The tool analyzes how genes have evolved across many species to uncover hidden clues about which gene is responsible for a patient's symptoms.

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22:29 GenEngNews.com Why Data Infrastructure Determines AI Success in Drug Discovery

The goal is to make good data practices the path of least resistance. Perhaps the most important requirement is software that experimental scientists can use naturally within their existing workflows. The post Why Data Infrastructure Determines AI Success in Drug Discovery appeared first on GEN - Genetic Engineering and Biotechnology News.

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22:29 GenEngNews.com Link Between Ceramide Transport and Cell Senescence Could Inform Aging Biology Research

An study showed how impaired transport protein and buildup of ceramides at the endoplasmic reticulum can help lock cells into replicative senescence, potentially pointing to avenues for research on cell aging. The post Link Between Ceramide Transport and Cell Senescence Could Inform Aging Biology Research appeared first on GEN - Genetic Engineering and Biotechnology News.

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20:46 Bioengineer.org Pediatric Gene Editing Trial for Methylmalonic Acidemia Advances

In a groundbreaking advancement that could reshape the landscape of genetic medicine, researchers have announced the successful completion of the first-ever clinical trial utilizing nuclease-free, homologous recombination-dependent gene editing in pediatric patients. This pioneering study, led by a team including Bedoyan, Morgan, and Sun, has targeted methylmalonic acidemia (MMA), a severe metabolic disorder, marking a […]

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19:59 Healio.com Gene therapy reduces geographic atrophy lesion growth

In a phase 2 trial, OCU410, a modifier gene therapy for geographic atrophy secondary to dry age-related macular degeneration, reduced lesion growth and size while slowing ellipsoid zone loss, according to a press release from Ocugen.“This outcome represents meaningful clinical and scientific validation of OCU410 but also further validation of our broader modifier gene therapy platform, giving us strong conviction as we advance into phase 3 and potential registrational pathway,” Shankar Musunuri, PhD, MBA, chairman, CEO and cofounder of Ocugen, told Healio.In the ArMaDa clinical trial, 51

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19:45 Entrepreneur.com Pharma Giant Eli Lilly Is Paying $2.75 Billion for Drugs Designed by AI – Here’s What It Gets Them

The company says using AI cuts years off of research time.

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19:13 TechnologyReview.com There are more AI health tools than ever—but how well do they work?

Earlier this month, Microsoft launched Copilot Health, a new space within its Copilot app where users will be able to connect their medical records and ask specific questions about their health. A couple of days earlier, Amazon had announced that Health AI, an LLM-based tool previously restricted to members of its One Medical service, would…

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18:37 CalClimateAg.org Community and Connection at the Burroughs Regenerative Tree Nut Field Day

Last week, CalCAN staff attended a regenerative tree nut field day at Burroughs Family Farms in Denair, CA. Ward and Rosie Burroughs along... The post Community and Connection at the Burroughs Regenerative Tree Nut Field Day appeared first on CalCAN - California Climate & Agriculture Network.

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18:10 MedicalXpress.com 20,000 lab-grown human retinas reveal how cone photoreceptor cells resist degeneration

Scientists led by Botond Roska at the Institute of Molecular and Clinical Ophthalmology Basel (IOB) and collaborators have identified genetic pathways and compounds capable of protecting cone photoreceptors from the degeneration that underlies conditions like age-related macular degeneration.

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17:10 Endpts.com Eli Lilly to pay $115M upfront to Insilico in AI drug discovery deal

Another key player in China's biotech ecosystem has landed a pharma deal. On Sunday, Eli Lilly and Insilico Medicine announced a drug discovery collaboration, with the Indianapolis drugmaker paying $115 million ...

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14:03 Yahoo.com Business Eli Lilly and Insilico Medicine forge $2.75bn AI-driven R&D pact

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12:49 Arxiv.org Physics Coupling Quantum Mechanical Modeling and Molecular Dynamics on Heterogeneous Supercomputers for Studying Distal Mutation Effects on Drug Binding in HIV-1

arXiv:2603.26411v1 Announce Type: new Abstract: Predicting how protein mutations affect drug binding remains a major challenge, particularly when the mutations are distal from the binding site. In this study, we introduce a coupled simulation workflow that combines long-time-scale molecular dynamics (MD) with high-throughput quantum mechanical (QM) analysis to reveal the electronic structure signatures of mutation induced drug resistance in the HIV-1 protease. Our workflow leverages GPU-accelerated MD to generate conformational ensembles, and performs in-operando linear-scaling density functional theory (DFT) calculations on selected frames parallelized on a coupled partition of CPU nodes. This design enables efficient, massively parallel quantum analysis of protein-ligand complexes at atomic resolution. Using this approach, we investigate resistance to the antiviral Darunavir in a multi-mutant HIV-1 protease variant. By mapping the network of electronic interactions across the

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12:49 Arxiv.org CS Doctorina MedBench: End-to-End Evaluation of Agent-Based Medical AI

arXiv:2603.25821v1 Announce Type: new Abstract: We present Doctorina MedBench, a comprehensive evaluation framework for agent-based medical AI based on the simulation of realistic physician-patient interactions. Unlike traditional medical benchmarks that rely on solving standardized test questions, the proposed approach models a multi-step clinical dialogue in which either a physician or an AI system must collect medical history, analyze attached materials (including laboratory reports, images, and medical documents), formulate differential diagnoses, and provide personalized recommendations. System performance is evaluated using the D.O.T.S. metric, which consists of four components: Diagnosis, Observations/Investigations, Treatment, and Step Count, enabling assessment of both clinical correctness and dialogue efficiency. The system also incorporates a multi-level testing and quality monitoring architecture designed to detect model degradation during both development and

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12:34 Medscape.Com New Gene Therapy Nears EU Nod for Bladder Cancer

Conditional approval of the intravesical gene therapy was supported by clinical evidence demonstrating a 53.4% complete response rate in patients with treatment-resistant non-muscle invasive bladder cancer.

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07:08 Technology.org AI tool streamlines drug synthesis

Drug discovery is like molecular Tetris. Chemists snap atoms together, adjusting the pieces until everything fits and suddenly,

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04:46 News-Medical.Net Chronic colitis reshapes colon stem cells in ways that can accelerate tumour growth

Researchers showed that chronic colitis leaves a long-lasting epigenetic memory in colonic stem cells, persisting for more than 100 days after recovery in mice. This memory is marked by durable AP-1-linked chromatin changes and later amplifies tumour outgrowth after oncogenic mutation.

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04:34 South China Morning Post Hong Kong-listed Insilico Medicine signs AI drug development deal with Eli Lilly

Insilico Medicine has signed a potential multibillion-dollar deal with Eli Lilly to license out an early-stage drug pipeline and provide its artificial intelligence platform services in research and development collaborations. Under the agreement announced on Monday, US-headquartered, Hong Kong-listed Insilico will receive an upfront payment of US$115 million. The deal could have a total value of around US$2.75 billion tied to development, regulatory and commercial milestones, plus tiered...

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03:37 Yahoo.com Business Eli Lilly extends partnership with Insilico Medicine for AI-powered drug discovery

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01:35 Phys.org Researchers describe protein structure microbes used to control light conversion

Wildfire smoke is teeming with them. Researchers have employed them to develop energy-dense biofuels like rocket, marine, and jet fuels. Scientists have engineered rice paddies that interact differently with them, causing lower methane "burping." They can be used to extract valuable metals like lithium and copper from plants like seaweed.

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01:23 Yahoo.com Business Eli Lilly leans into AI drug discovery with new licensing deal

The latest news and headlines from Yahoo! News. Get breaking news stories and in-depth coverage with videos and photos.

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00:07 Bioengineer.org Fetal Reversion Drives Intestinal Regeneration and Safeguards Stem Cell Integrity

In a groundbreaking study published in Communications Biology, researchers from the Institute of Science Tokyo have unveiled a remarkable cellular mechanism underlying intestinal regeneration. This discovery illuminates how the intestine efficiently repairs itself after damage without depleting its vital stem cell reserve. By exploring the dynamic interplay between specialized revival stem cells and conventional intestinal […]

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29.03.2026
23:52 Bioengineer.org Snail-Inspired Soft Robots Revolutionize Precision Drug Delivery for Bowel Cancer

In a groundbreaking advancement that bridges biology, materials science, and robotics, researchers at The University of Manchester have secured nearly £1 million in funding from UK Research and Innovation (UKRI) to develop innovative soft robots inspired by the locomotion of snails. These microscopic robots are specifically engineered to revolutionize the delivery of anti-cancer drugs with […]

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23:36 MedicalXpress.com After allogeneic transplant, VIC-1911 regimen shows low severe GVHD and no relapse

Results of a Phase I clinical trial show that patients who undergo a blood stem cell transplant involving a donor have a lower risk of relapse and lower rates of graft-versus-host disease when they receive the targeted therapy VIC-1911 along with the standard-of-care regimen that includes post-transplant cyclophosphamide and sirolimus.

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23:25 Benzinga.com Eli Lilly Secures $2.75 Billion Deal With Insilico Medicine To Bring AI-Developed Drugs To Global Market: Report

Eli Lilly's deal involves an upfront payment of $115 million to Insilico, with additional payments tied to milestones. Importance Rank:  1 read more

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22:35 Bioengineer.org Global Assessment: Regenerative Farming Boosts Crop Yields

As the global population continues its inexorable rise, the pressure on agriculture to meet increasing food demands has never been more intense. In this context, the promise of regenerative farming practices emerges not only as a beacon of hope but also as a scientifically grounded approach to reconciling yield enhancement with environmental sustainability. A groundbreaking […]

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17:03 TechMeme.com Hong Kong-listed AI drug discovery company Insilico Medicine and Eli Lilly sign a drug co-development deal worth up to $2.75B, with $115M in upfront payments (Evelyn Cheng/CNBC)

Evelyn Cheng / CNBC: Hong Kong-listed AI drug discovery company Insilico Medicine and Eli Lilly sign a drug co-development deal worth up to $2.75B, with $115M in upfront payments  —  BEIJING — U.S. pharmaceutical giant Eli Lilly has reached a $2.75 billion deal to bring drugs developed using artificial intelligence …

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16:52 SeekingAlpha.com Eli Lilly expands AI drug push with multibillion-dollar Insilico deal

© seekingalpha.com. Use of this feed is limited to personal, non-commercial use and is governed by Seeking Alpha's Terms of Use (https://about.seekingalpha.com/terms). Publishing this feed for public or commercial use and/or misrepresentation by a third party is prohibited.

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16:49 CNBC technology Eli Lilly reaches $2.75 billion deal with Insilico to bring AI-developed drugs to the global market

U.S. pharmaceutical giant Eli Lilly will give Hong Kong-listed Insilico $115 million upfront to bring some of its AI-discovered drugs to the global market.

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16:49 CNBC health care Eli Lilly reaches $2.75 billion deal with Insilico to bring AI-developed drugs to the global market

U.S. pharmaceutical giant Eli Lilly will give Hong Kong-listed Insilico $115 million upfront to bring some of its AI-discovered drugs to the global market.

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16:49 CNBC top news Eli Lilly reaches $2.75 billion deal with Insilico to bring AI-developed drugs to the global market

U.S. pharmaceutical giant Eli Lilly will give Hong Kong-listed Insilico $115 million upfront to bring some of its AI-discovered drugs to the global market.

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16:44 ScienceDaily.com Stroke triggers a hidden brain change that looks like rejuvenation

After a stroke, the brain may do something surprisingly hopeful—it can “refresh” parts of itself. Researchers analyzing brain scans from over 500 stroke survivors found that while the damaged side of the brain appears to age faster, the opposite, unaffected side can actually look younger. This unexpected shift seems to reflect the brain’s effort to rewire itself, strengthening healthy regions to compensate for lost function.

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14:58 HighTech.plus Физическая форма ДНК – причина ошибок редактирования CRISPR

Ученые обнаружили, что главная проблема генной терапии может быть связана не с ошибками самих инструментов редактирования. Причину нашли в физической форме ДНК. Оказалось, что скручивание ДНК напрямую влияет на то, как CRISPR находит и разрезает гены, и именно это может объяснять неожиданные ошибки при лечении.

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06:12 TechMeme.com Qualified Health, which helps health systems evaluate and adopt AI tools, raised a $125M Series B led by NEA at a valuation of between $500M and $1B (Heather Landi/Fierce Healthcare)

Heather Landi / Fierce Healthcare: Qualified Health, which helps health systems evaluate and adopt AI tools, raised a $125M Series B led by NEA at a valuation of between $500M and $1B  —  Qualified Health Artificial Intelligence New Enterprise Associates SignalFire  —  Qualified Health, a startup that works with health systems …

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03:35 Yahoo.com Business How The Ocugen (OCGN) Narrative Is Shifting With Retinal Gene Therapy Data And New Valuations

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28.03.2026
18:39 MedicalXpress.com FDA approves gene therapy for severe leukocyte adhesion deficiency-I, a rare immune disorder

Dr. Donald Kohn has been developing gene therapies for rare pediatric immune disorders for over 30 years. This week, his role in a clinical trial has culminated in the first-ever U.S. Food and Drug Administration–approved therapy for severe leukocyte adhesion deficiency-I—a genetic condition characterized by recurrent infections and, often, early death.

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15:14 LiveScience.com A gut microbe linked to the Mediterranean diet boosts muscle strength in mice

Researchers are exploring the prospect of using gut bacteria to boost muscle strength, after zeroing in on a microbe that does this in mice

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14:48 Yahoo Finance The Future Is Now: 2 Medical Diagnostic AI Stocks to Snap Up

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06:42 Yahoo.com Business Cathie Wood Chooses Medical AI Over Mark Zuckerberg: Ark Loads Up On TEM Stock, Dumps Meta Shares

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04:50 Yahoo.com Business Cathie Wood Chooses Medical AI Over Mark Zuckerberg: Ark Loads Up On TEM Stock, Dumps Meta Shares

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27.03.2026
22:39 News-Medical.Net FDA approves first gene therapy for rare pediatric immune disorder

Dr. Donald Kohn has been developing gene therapies for rare pediatric immune disorders for over 30 years.

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21:11 News-Medical.Net Advanced endoscopic technique successfully treats early-stage colorectal cancer

In the months before his wedding, Queens resident Roberto Pineda Sanchez noticed persistent rectal bleeding, a dangerous symptom he almost ignored.

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20:42 MedicalXpress.com A new view of intestinal regeneration: What fetal reversion could mean for IBD and cancer

Dynamic switching between revival stem cells and conventional intestinal stem cells enables efficient tissue repair without exhausting the stem cell pool, report researchers from Institute of Science Tokyo. Using organoid and mouse disease models, the researchers uncovered how flexible stress-tolerant cell states contribute to intestinal repair—providing a better understanding of the biological mechanisms driving intestinal regeneration.

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20:13 MedicalXpress.com Guidance for safer AI-enabled medical devices: Researchers highlight the importance of human factors

AI-enabled medical devices promise improved medical care and support for health care professionals. However, the safety and performance of such systems not only depends on algorithms or technical specifications. It is equally important how people use these devices and applications. In a recent publication in the journal NEJM AI, a research team led by Prof. Stephen Gilbert from Else Kröner Fresenius Center (EKFZ) for Digital Health at TUD Dresden University of Technology systematically analyzes risks that can arise in human-AI interactions and makes recommendations for manufacturers and regulatory evaluators.

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19:44 SiliconRepublic.com How does mentorship impact a professional’s career longevity?

SiliconRepublic.com spoke with experts at Amgen to explore how early career guidance can set the foundations for a happy and productive career. Read more: How does mentorship impact a professional’s career longevity?

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19:13 Medscape.Com FDA Approves First Gene Therapy for Severe LAD-1

Marne-cel now offers an option to children with the rare immune disorder who lack a sibling donor for stem cell transplantation.

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18:28 Endpts.com FDA approves Rocket's gene therapy for ultra-rare immune disease

A rare disease gene therapy from Rocket Pharmaceuticals has garnered FDA approval after an earlier rejection for manufacturing problems. The FDA on Thursday granted accelerated approval to Rocket Pharma’s gene therapy ...

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18:23 GenEngNews.com Stem Cells at the Frontier: Breakthroughs, Barriers, and What’s Next

This GEN Live show will focus on new areas of stem cell research, including aging. It will bring together a panel of leading experts to unpack the latest advances and ongoing challenges in stem cells. The post Stem Cells at the Frontier: Breakthroughs, Barriers, and What’s Next appeared first on GEN - Genetic Engineering and Biotechnology News.

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18:03 Yahoo Finance What Makes Intuitive Surgical (ISRG) a Clear Leader in Robotic-Assisted Surgery?

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17:29 MedicalXpress.com AI learns to make sense of childhood cancer survivors' health care needs

Artificial intelligence (AI) could help physicians determine if survivors of childhood cancer need extra support—and the more information included in AI prompting, the better its performance. This finding, published in Communications Medicine by scientists from St. Jude Children's Research Hospital, may guide future integration of AI into clinical workflows.

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17:19 SeekingAlpha.com Medtronic cleared to market robotic surgical system for cranial procedures

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16:04 BMJ.com Meta and Google are found liable for harm to child’s mental health in landmark ruling

A US jury has ruled that deliberately addictive features of apps owned by Meta and Google harmed a young user’s mental health.The ruling, by the California Superior Court of Los Angeles, found that the platforms were deliberately designed in ways that contributed to the anxiety, depression, and body dysmorphia of the plaintiff KGM, as she is referred to in court documents, now a 20 year old woman.KGM’s lawyers argued that algorithmic recommendations, “likes,” push notifications, and autoplaying videos, among other features, were engineered to encourage compulsive use and exploited developmental vulnerabilities in KGM. This, they claimed, had contributed to a deterioration in her mental health.Meta reportedly argued that KGM’s mental health problems, including body dysmorphia and thoughts of self-harm, were caused by familial abuse and turmoil.1 However, the company added that it no longer set internal targets for user time spent on its platform.The video sharing platform YouTube, owned

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14:37 DigitalTrends.com SATELLAI Collar is pushing the boundaries of dog safety and health care with PetSense AI

Discover the future of pet safety with SATELLAI. From 5-way GNSS satellite tracking to PetSense AI health analysis, these smart collars offer precision and peace of mind for every dog and terrain.

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13:55 SeekingAlpha.com Rocket Pharma rises as FDA approves gene therapy

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13:52 Arxiv.org CS Rethinking Health Agents: From Siloed AI to Collaborative Decision Mediators

arXiv:2603.24986v1 Announce Type: new Abstract: Large language model based health agents are increasingly used by health consumers and clinicians to interpret health information and guide health decisions. However, most AI systems in healthcare operate in siloed configurations, supporting individual users rather than the multi-stakeholder relationships central to healthcare. Such use can fragment understanding and exacerbate misalignment among patients, caregivers, and clinicians. We reframe AI not as a standalone assistant, but as a collaborator embedded within multi-party care interactions. Through a clinically validated fictional pediatric chronic kidney disease case study, we show that breakdowns in adherence stem from fragmented situational awareness and misaligned goals, and that siloed use of general-purpose AI tools does little to address these collaboration gaps. We propose a conceptual framework for designing AI collaborators that surface contextual information, reconcile

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13:30 TomsHardware.com Exceptional fake SSD clone of Samsung 990 Pro is almost impossible to spot — near-identical performance blurs the line between real and fake as AI crunch drives knock-off market

Japanese news outlet Akiba PC Hotline! examines a fake Samsung 990 Pro SSD that's starting to show up in the Japanese market.

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12:12 TechnologyReview.com Here’s why some people choose cryonics to store their bodies and brains after death

This week I reported on some rather unusual research that focuses on the brain of L. Stephen Coles. Coles was a gerontologist who died from pancreatic cancer in 2014. He had spent the latter part of his career specializing in human longevity. And before he died, he decided to have his brain preserved by a…

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05:21 TechMeme.com NY-based Blossom Health, which makes an "AI copilot" to augment psychiatrists' clinical decisions and automate office tasks, raised $20M in seed and Series A (Lily Mae Lazarus/Fortune)

Lily Mae Lazarus / Fortune: NY-based Blossom Health, which makes an “AI copilot” to augment psychiatrists' clinical decisions and automate office tasks, raised $20M in seed and Series A  —  Blossom Health has raised $20 million in seed and Series A funding to bring an AI “copilot” for psychiatry to patients nationwide, Fortune has exclusively learned.

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02:01 MedicalXpress.com Kidney transplant system could be missing opportunity to save more lives and reduce costs

Despite an urgent demand for kidney donors in the U.S., about 1 in 4 donor kidneys goes unused. In 2022, more than 71,000 people were on the kidney transplant waiting list, with waitlists often extending as long as five years for a donor kidney.

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00:53 Phys.org DNA shape explains crucial gene-therapy challenges

CRISPR is a powerful DNA-editing tool that has underpinned huge advancements in human health care in the last decade. It is a precision tool, but is not perfect, and misplaced DNA edits can compromise safety and efficacy, costing billions each year. Researchers at the MRC Laboratory of Medical Sciences (LMS), Imperial College London and the University of Sheffield have published research in Nature showing that the physical twisting of DNA plays an important role in these mistakes. Using a newly developed platform of tiny (nanometer-sized) DNA circles, called DNA minicircles, the team captured never-before-seen interactions between CRISPR and DNA, providing insights that could help eradicate errors altogether.

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00:53 Google news Health Structural basis of supercoiling-induced CRISPR–Cas9 off-target activity - Nature

Structural basis of supercoiling-induced CRISPR–Cas9 off-target activity  Nature

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00:53 Google news Sci/Tech Structural basis of supercoiling-induced CRISPR–Cas9 off-target activity - Nature

Structural basis of supercoiling-induced CRISPR–Cas9 off-target activity  Nature

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26.03.2026
23:14 TheNextWeb.com Blossom Health raises $20 million to put AI copilots alongside psychiatrists

Blossom Health, a New York-based telepsychiatry startup founded in 2024, has raised $20 million in combined seed and Series A funding to scale an AI-powered platform that pairs psychiatrists with clinical copilots and automated administrative support. The round was led by Headline, whose co-founder and managing partner Mathias Schilling is joining the company’s board. Village […] This story continues at The Next Web

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22:36 NewYork Times How a Healthy Mind-Set Influences Longevity

A few qualities, including a sense of purpose, seem to have real benefits — especially as you age.

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21:41 FoxNews.com NHL star's fiancée makes emotional return after undergoing harrowing heart transplant ordeal

Rasmus Dahlin's fiancée Carolina Matovac returned to a Sabres game months after suffering major heart failure and receiving a transplant in France.

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21:23 Science.org Distinctive DNA sequence features define epigenetic longevity of inflammatory memory | Science

Tissues harbor memories of inflammation, which heighten sensitivity to diverse future assaults. Whether and how these adaptations are sustained through time and cell division remain poorly understood. We show that in mice, epidermal stem cells store ...

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19:45 AgWeek.com Minnesota is among Midwest states looking to regulate lab-grown meat and food

While Minnesota tries to make sure cell-cultured food is labeled as such, South Dakota has passed a moratorium on any lab-grown meat in the state.

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14:55 Benzinga.com EXCLUSIVE: Hoth Therapeutics Targets Faster Drug Discovery With New AI Platform

Hoth Therapeutics launches OpenClaw AI platform to speed drug discovery, improve data integration, and boost development efficiency. Importance Rank:  1 read more

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13:55 Google news Health How a Healthy Mind-Set Influences Longevity - The New York Times

How a Healthy Mind-Set Influences Longevity  The New York TimesPeople 65 and older can get better with age, study shows. This is the key.  The Washington PostThe condition of many elderly people actually improves over the years – and this is the reason  The Jerusalem PostA 103-Year-Old Woman Says This Simple Habit Is The Secret To A Long Life — And Research Backs Her Up  YourTangoAgeing does not always mean decline  diabetes.co.uk

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13:55 Google news Sci/Tech How a Healthy Mind-Set Influences Longevity - The New York Times

How a Healthy Mind-Set Influences Longevity  The New York TimesPeople 65 and older can get better with age, study shows. This is the key.  The Washington PostThe condition of many elderly people actually improves over the years – and this is the reason  The Jerusalem PostA 103-Year-Old Woman Says This Simple Habit Is The Secret To A Long Life — And Research Backs Her Up  YourTangoAgeing does not always mean decline  diabetes.co.uk

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09:58 SeekingAlpha.com Health In Tech outlines $45M–$50M 2026 revenue target while advancing AI platform and large employer rollout

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09:26 Arxiv.org Math Higher-order Ricci estimates along immortal K\"ahler-Ricci flows

arXiv:2603.24380v1 Announce Type: new Abstract: We study higher-order curvature estimates along K\"ahler-Ricci flows on compact K\"ahler manifolds of intermediate Kodaira dimension. We prove that away from singular fibers, the Ricci curvature is uniformly bounded in $C^1$, the Laplacian of the Ricci curvature in $C^0$, and the scalar curvature in $C^2$. We identify a geometric obstruction to higher-order curvature bounds, whose non-vanishing causes a specific third-order derivative of the Ricci curvature to blow up at rate $e^{t/2}$. Uniform $C^k$ bounds for every $k$ hold for the Ricci curvature in the isotrivial case, and for the full Riemann curvature in the torus-fibered case.

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09:26 Arxiv.org CS Praxium: Diagnosing Cloud Anomalies with AI-based Telemetry and Dependency Analysis

arXiv:2603.23890v1 Announce Type: new Abstract: As the modern microservice architecture for cloud applications grows in popularity, cloud services are becoming increasingly complex and more vulnerable to misconfiguration and software bugs. Traditional approaches rely on expert input to diagnose and fix microservice anomalies, which lacks scalability in the face of the continuous integration and continuous deployment (CI/CD) paradigm. Microservice rollouts, containing new software installations, have complex interactions with the components of an application. Consequently, this added difficulty in attributing anomalous behavior to any specific installation or rollout results in potentially slower resolution times. To address the gaps in current diagnostic methods, this paper introduces Praxium, a framework for anomaly detection and root cause inference. Praxium aids administrators in evaluating target metric performance in the context of dependency installation information provided by

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08:19 HealthPopuli.com Consumers Using AI for Health — Especially Motivated When People Lack Access to Care

Peoples’ use of AI for researching health information and supporting mental health appears to trump consumers’ trust in the technology, based on the March 2026 Kaiser Family Foundation (KFF) Tracking Poll on Health Information and Trust.          Similar to the recent Rock Health consumer survey on AI adoption (discussed in Health Populi earlier this week), about 1 in 3 U.S. adults have used AI for health information in the past year for either physical or mental health queries.              There are many studies gauging consumers’ use of AI in health care, but KFF uniquely surfaced an important nuance in this study regarding just “who” is more likely to use AI for health: that is that younger and lower income adults were much more likely to cite not being able to access or afford health care, and were thus motivated to turn to AI for health advice.                

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06:53 Benzinga.com Cathie Wood Chooses Medical AI Over Mark Zuckerberg: Ark Loads Up On TEM Stock, Dumps Meta Shares

Cathie Wood's Ark Invest bought Tempus AI shares while trimming Meta, signaling a shift toward medical AI over big tech exposure. Importance Rank:  1 read more

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06:10 KoreaTimes.co.kr Why is the Mediterranean diet so effective?

Click here for more articles by Kormedi.com. A new study suggests that what you eat may influence proteins inside your cells, specifically those in the mitochondria. The Mediterranean diet — rich in olive oil, vegetables, fruits, whole grains, fish and legumes, while limiting red meat and processed foods — is already known to benefit heart and brain health. However, exactly how it works in the body has remained unclear. Study sheds light on what’s happening inside cells Researchers from the University of Southern California and Sapienza University of Rome found that people who closely followed the Mediterranean diet had higher levels of two mitochondrial proteins. The study involved 49 elderly patients (average age of 78) with non-valvular atrial fibrillation, a condition that increases stroke risk. These patients tend to have high oxidative stress — a condition where harmful reactive oxygen species outweigh the body’s defenses — making it easier to detect diet-related changes.

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02:52 South China Morning Post Chinese nationals, companies charged in US with smuggling AI chips and drug trafficking

In two different cases on Wednesday, United States authorities indicted Chinese nationals on charges ranging from conspiring to smuggle advanced AI chips to China to drug trafficking and money laundering. The cases came on the same day US President Donald Trump announced new mid-May dates for his highly anticipated summit with China. The developments come as the two countries continue to compete over global leadership in artificial intelligence, and as Washington continues to accuse Beijing of...

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00:43 Phys.org Protein modification discovery opens cancer therapy possibilities

A research team led by Purdue University's W. Andy Tao has discovered a new type of protein modification related to cellular mutation that impairs a crucial enzyme's ability to help drive energy processes. Their discovery, published in Nature Chemistry, opens a new route to therapeutic cancer intervention.

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00:36 GenEngNews.com Leveraging the Full Potential of Regenerative Medicine Requires a Proactive Approach

If responsibly developed and thoughtfully integrated into healthcare systems, regenerative therapies could help shift medicine toward a more proactive model, i.e., one focused on preserving health, maintaining function, and extending healthy lifespan. The post Leveraging the Full Potential of Regenerative Medicine Requires a Proactive Approach appeared first on GEN - Genetic Engineering and Biotechnology News.

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00:15 Phys.org RNA-guided CRISPR system activates gene expression

In back-to-back studies published in Nature, researchers from Purdue University and Columbia University report a naturally evolved gene-editing system that can activate genes, offering an advantage over existing CRISPR gene-editing systems that merely find and cut DNA. The research includes two complementary studies, one examining the biological function of the system and the other revealing the molecular mechanism that enables it.

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25.03.2026
21:42 FightAging.org Aging Impairs Activation of Muscle Stem Cells, with MG53 as a Potential Target for Therapies

Researchers have identified many contributing issues leading to the characteristic loss of muscle mass and strength that takes place with age. Arguably the central problems are (a) the disruptions of cell behavior caused by chronic inflammation, (b) damage to neuromuscular junctions, depriving muscle tissue of signals it relies upon for normal maintenance to take place, and (c) loss of muscle stem cell activity, and thus a reduced supply of somatic muscle cells to replace losses. These central problems likely interact with one another, but in principle could be addressed distinctly to produce benefits in patients. Past studies have shown, rather convincingly, that muscle stem cells in older individuals retain their function when moved from an old environment to a young environment. The problem is not […]

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20:53 NewScientist.Com How working out like an astronaut can reduce back pain and slow ageing

The same principles that help astronauts stay strong in microgravity can help us all resist the slow collapse of ageing – and it’s not all about hitting the gym more

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20:18 Nature.com (news) Structural basis of supercoiling-induced CRISPR–Cas9 off-target activity

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20:09 Nature.Com Structural basis of supercoiling-induced CRISPR–Cas9 off-target activity

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19:53 NewScientist.Com Landmark experiment reveals a big unexpected problem with cloning

A 20-year study has shown that, like photocopying photocopies, cloning doesn't produce perfect copies – with big implications for farming, conservation and de-extinction

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16:20 Yahoo.com Business Ocugen’s GA gene therapy garners mixed sentiments on 12-month Phase II readout

The latest news and headlines from Yahoo! News. Get breaking news stories and in-depth coverage with videos and photos.

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15:38 Benzinga.com BullFrog AI Unveils Decision Engine To Tackle Drug Development Uncertainty

BullFrog AI launches bfARENAS, a scenario-based platform to improve R&D decisions and reduce risk in drug development portfolios. Importance Rank:  1 read more

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