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A five-center study shows deep learning models, especially nnU-Net, predict aggressive meningioma grades from MRI more reliably across hospitals than handcrafted radiomics, which collapsed under external validation.

In a Columbia University School of Nursing study surveying 1,185 U.S.-based adults about AI use in secure medical portals, 63% of patients said they would not endorse AI-generated medical responses without a clinician's review. This suggests that while patients see value in using AI for certain health care tasks, they prefer a human review when medical advice is involved. The study, "Public Perceptions of Timeliness for AI Use and Human Oversight," was published in the JAMA Network Open on Oct. 14, 2026.

Researchers at the University of Cincinnati College of Medicine have published the first proof-of-concept study showing the potential of an experimental gene therapy for hydrocephalus.

A new multimodal AI framework called MEGH-DDI combines chemical language models with graph neural networks to predict drug–drug interactions with over 98 percent accuracy.

Researchers at the University of Cincinnati College of Medicine have published the first proof-of-concept study showing the potential of an experimental gene therapy for hydrocephalus. The preclinical research from the lab of Agnes (Yu) Luo was recently published in the journal Fluids and Barriers of the CNS, which focuses on specialized cerebrospinal fluid (CSF) biology.

Researchers report that suppressing the lipid-metabolizing enzyme PLA2G7 in hippocampal neural stem cells restores inhibitory synapses and improves memory in aged mice.

A University of Cincinnati and UC Davis team showed that an AAV gene therapy targeting cerebrospinal fluid-producing cells reduced hydrocephalus-related brain swelling in animal models, pointing toward a minimally invasive alternative to shunt surgery.

For a long time, differences between females and males were mainly associated with the reproductive organs. Yet organs that have nothing to do with reproduction, such as the skin, can also be shaped by sex.

Every organ and tissue progressively loses function and integrity as it ages. In fact, researchers have identified "hallmarks of aging" that not only present specific processes impacted by age, but are also thought of as levers that, if successfully targeted, could help turn back the aging clock and result in tissue rejuvenation.

The on-demand availability of artificial intelligence chatbots means that most individuals have quick, easy access to a wealth of information. The ease and accessibility of these tools may make it tempting to turn to AI for advice about mental health. But it's important to note that these systems are prone to reinforcing a user's existing beliefs or, in some cases, providing inaccurate information.

His comments come after Merck officially opened its new 120,000-square-foot research facility in the Greater Philadelphia area.

The pancreas is a complex organ comprising multiple cell types that regulate blood glucose levels through hormones, such as insulin, and support digestion by producing digestive enzymes. Researchers at the University of Tsukuba previously developed an intraplacental transplantation method whereby pancreatic progenitor cells are injected into the placenta of a pregnant mouse and delivered to the developing fetus. However, whether transplanted cells could become incorporated into pancreatic tissue had not been demonstrated.

NASHVILLE, Tenn. — AI tools were less likely to flag emergencies and deliver accurate, comprehensive gastroenterology advice in the six most common U.S. languages after English, according to a presenter at ACG Annual Scientific Meeting.“AI is already part of everyday life, and people are turning to it with health questions, often before speaking with a physician,” Harika Dadigiri, MD, resident physician at New York Medical College at Saint Mary’s and Saint Clare’s Hospital in New Jersey, told Healio regarding her presentation. “For patients who struggle to find reliable medical information in

A new review in Cellular and Molecular Life Sciences proposes hybrid biological-digital tumor twins, coupling patient-derived organoids with computational models in closed feedback loops, as a blueprint for adaptive precision oncology in breast cancer.

OpenEvidence and Johns Hopkins Medicine partner to develop AI tools for physician training and clinical care, with a focus on medical reasoning and patient safety. The post OpenEvidence, Johns Hopkins Partner to Bring AI Into Medical Training and Patient Care appeared first on TechRepublic.

The American Society of Hematology (ASH) has released guidelines on the management of myelofibrosis, a rare and life-threatening blood cancer. The new guidelines recommend expanded molecular testing, early transplant referral, appropriate use of JAK inhibitors and aspirin therapy in select patients.

Researchers combined structure-guided protein design with cis-regulatory editing at the native HPPD locus to create elite herbicide-tolerance alleles in rice and wheat.

Researchers in Wuhan developed a two-stage deep learning system that detects and classifies postoperative coughs from audio recordings of lung surgery patients with over 99 percent accuracy on clean data, while flagging noise robustness as the key hurdle before clinical deployment.

A new Journal of Medical Systems commentary proposes a task-level oversight-margin framework to quantify when human supervision of cardiovascular artificial intelligence falls behind the pace of algorithmic output.

With artificial intelligence making deep inroads into health care, two doctors are urging physicians to embrace the technology but to remember that only humans can serve the best interests of individual patients.

Boca Raton, Florida, October 14th, 2026, Financewire Collaboration combines INmune Bio’s clinical research with QCi’s Dirac-3S quantum optimization machine to identify potential new treatment indications and biomarkers for XPro. Initial engagement marks QCi’s first commercial customer in pharmaceutical and biotechnology markets, expanding the application of quantum computing to drug development. INmune Bio Inc. (Nasdaq: INMB) […] This story continues at The Next Web

Genome editing is moving beyond experimental promise, as a customized therapy for a rare genetic disorder highlights both its clinical potential and the barriers to broader access.

Pope diagnosed with lung cancer but had successful surgery, Vatican says  BBCWhat to Know About Pope Leo’s Cancer Diagnosis  The New York TimesPope Leo spends a peaceful night in the hospital after cancer surgery  NBC NewsWhat to know about pulmonary adenocarcinoma  The Washington PostFirst Thing: Pope Leo recovering from surgery after lung cancer diagnosis  The Guardian

Pope diagnosed with lung cancer but had successful surgery, Vatican says  BBCWhat to Know About Pope Leo’s Cancer Diagnosis  The New York TimesPope Leo spends a peaceful night in the hospital after cancer surgery  NBC NewsWhat to know about pulmonary adenocarcinoma  The Washington PostFirst Thing: Pope Leo recovering from surgery after lung cancer diagnosis  The Guardian

A new Journal of Medical Systems Comment argues that how clinical AI systems select cases for human review must itself be rigorously evaluated to keep oversight meaningful.

A new deep learning radiomics model built on preoperative multiparametric MRI achieved AUCs up to 0.95 in predicting three-year breast cancer recurrence-free survival and successfully stratified patients into distinct risk groups.

The data behind Blue Zones might not be that strong

The large language model took less than a day to identify the curious stretch of DNA

A new meta-analysis of seven randomized controlled trials finds that vitamin D supplementation does not significantly alter circulating levels of the exercise-linked hormone irisin or the longevity-associated protein SIRT1, despite suggestive signals in small subgroups.

Since stem cell therapies produce beneficial effects via a short burst of signaling from the transplanted cells rather than via any long-lasting survival and engraftment of those cells, researchers are attempting to build therapies that deliver the signals instead of the cells. Manufacture involves culturing stem cells and harvesting the culture medium in order to obtain the molecules or extracellular vesicles secreted by the stem cells, and then introducing that material into patients. The signaling produced by different stem cell populations will likely prove to be more versus less useful in different contexts, and so some experimentation is needed. Here, researchers show that the secreted signals generated by dental pulp stem cells help to improve the outcome following stroke in mice. Ischemic stroke induces oxidative […]

Living longer and healthier is important. But don’t believe everything you hear.

A Virginia Tech-led study finds that a voluntary priority program matching older donor kidneys with patients over 65 could add more than 900 kidney transplants and prevent over 190 deaths in the United States each year.

Pope Leo diagnosed with lung cancer, undergoes successful surgery  AxiosPope Leo Diagnosed With Lung Cancer After Surgery  WSJPope Leo spent peaceful night in hospital after surgery, Vatican says  ReutersWhat to know about pulmonary adenocarcinoma  The Washington PostWho’s in charge when the pope is unconscious and unable to govern? The pope  AP News

Pope Leo diagnosed with lung cancer, undergoes successful surgery  AxiosPope Leo has calm night in hospital after successful lung surgery  Vatican NewsWhat to know about pulmonary adenocarcinoma  The Washington PostWho’s in charge when the pope is unconscious and unable to govern? The pope  AP NewsPope Leo spent peaceful night in hospital after surgery, Vatican says  Reuters

A retrospective study found that combining a thymoma with a three-millimeter rim of surrounding tissue on CT scans improved machine learning prediction of perioperative complications in myasthenia gravis patients, though the absolute accuracy remained modest.

Experts discuss the draw of longevity clinics, potential risks, and how physicians can respond without abandoning evidence-based care.

An Indian research team has developed GraphX, an explainable graph transformer framework that classifies nail diseases with 94.97 percent accuracy while showing clinicians exactly where its attention focused.

arXiv:2610.16093v1 Announce Type: new Abstract: Predicting single-cell perturbation responses requires mapping between two unpaired populations of cells measured before and after the perturbation. Optimal transport (OT) provides a principled framework for constructing such mappings by minimizing the transport cost, and neural OT methods (\textit{e.g.}, CellOT) have been employed for this prediction task. However, these methods rely on a fixed transport cost, typically the squared Euclidean distance. This cost may connect cells with the wrong responses. Lineage tracing provides the information needed to learn the cost, as heritable barcodes link the cells of the same clone before and after the perturbation. Here, we propose \CloneOT, a neural inverse OT method that learns both the transport cost and the transport map from partially lineage-traced single-cell datasets. \CloneOT\ represents the cost as a neural network. It learns the cost by minimizing the extra cost that the lineage

arXiv:2610.13993v1 Announce Type: new Abstract: Therapeutic sutures can localize bioactive payloads to wounds, but burst release and insufficient coating durability can compromise regeneration and increase infection risk. In this work, we introduce a data-driven discovery strategy for bioresorbable polymer suture coatings that improve therapeutic retention and release kinetics. We develop GenPoly, an end-to-end multimodal generative framework that learns a shared polymer representation over paired polymer string sequences and molecular graphs via contrastive alignment, and couples this representation to property prediction, synthetic accessibility filtering, and motif-based candidate clustering to discover coating families beyond commonly used linear aliphatic polyesters. Starting from a clinically prevalent baseline, GenPoly identifies candidate coatings and selects representative polymers for experimental evaluation on nanoparticle-loaded sutures with recombinant human EGF to an in

arXiv:2610.15329v1 Announce Type: new Abstract: In this paper, {we propose a new family of $(n, k)$ Minimum Storage Regenerating (MSR) codes} for distributed storage systems. By structuring the parity-check matrix as a block Vandermonde matrix composed of diagonal matrices and generalized permutation matrices, the proposed code achieves a sub-packetization level of $N = (d-k+1)^{\lceil\frac{n}{2}\rceil}$ and supports any repair degree $k+1\le d

Researchers combined manganese-doped ZnO/silica nanocomposites with machine learning and digital colorimetry to achieve rapid, nondestructive quality control and 96% visible-light degradation of the antiviral drug lopinavir in water.

Biotechnology company QUiCKR Bio is using liquid handling solutions from INTEGRA Biosciences to run its CRISPR edit confirmation assays.

Scientists have long used a powerful gene-editing tool called CRISPR to make precise changes to DNA. But a different version of the technology, known as Cas13a, targets RNA, the genetic material found in viruses such as HIV.

Researchers have created an injectable self-healing hydrogel of gelatin and hyaluronic acid that slowly releases b-FGF and dramatically improves the survival of transplanted fat tissue in rats.

Researchers have developed a Matrigel-free, aloe vera-containing bioink for 3D-printing bone organoids that recruit and polarize macrophages toward a pro-regenerative state, accelerating repair of critical-sized skull defects in rats.

A comparative proteomics pipeline and the first CRISPR-Cas9 gene editing in Fasciola hepatica juveniles have identified three surface-exposed proteins as promising early-stage vaccine candidates against liver fluke disease.

A new safety audit shows that machine unlearning in medical AI can silently degrade performance on rare diagnoses, and proposes a framework to detect and mitigate this spillover.

Surgeons have shown that robotic technology can help repair a rare and difficult type of hernia that develops along the side of the abdomen. These hernias are hard to treat because they form near the ribs, pelvis, muscles, nerves and blood vessels.

VIB researchers have developed a new human stem-cell-based model that recreates an early stage of immune-cell development and shows how a single progenitor population can give rise to specialized macrophages across different organs. The model provides a platform to study how these processes change in disease, and how they might eventually be harnessed therapeutically.

Google is investing in Flo Health to connect menstrual cycle tracking with wearable data, expand women's health research, and develop personalized AI tools. The post Google Invests in Flo Health to Bring Period Tracking to Wearables appeared first on TechRepublic.

Researchers identified eleven WOX genes in the medicinal tree Eucommia ulmoides and showed that overexpressing EuWOX11 in poplar dramatically increases adventitious root formation, root length, biomass and vegetative growth.

Some people are born with a defect in their genetic material that prevents their immune system from functioning properly. In people with a condition known as GATA2 deficiency, the body does not produce enough immune cells, leaving them at increased risk of infections and disease. Now, researchers at Aarhus University have demonstrated that they can repair the genetic defect directly in patients' own blood stem cells.

Researchers have developed a three-stage protocol that reliably converts adipose-derived mesenchymal stem cells into functional lymphatic endothelial precursor cells, which engraft into host lymphatic vessels in a mouse wound-healing model.

A deep learning model trained exclusively on adult duodenal biopsy images has achieved pathologist-level accuracy in diagnosing coeliac disease in children across independent hospitals and scanner platforms, with no misclassifications among high-confidence predictions.

Chinese researchers have built an interpretable FTIR spectroscopy and machine learning framework that reliably distinguishes raw, nine-steamed-and-nine-sun-dried, honey-processed, and wine-processed Polygonatum sibiricum products.

Researchers used graphene oxide to restructure stem cell spheroids into multiple smaller aggregates, nearly doubling exosome yield and producing vesicles that accelerated vascularized wound healing in rats.

A map built from more than 14,000 embryo cells reveals what stem cell models get right about early human development and where researchers could improve them. Under a microscope, a cluster grown from stem cells can resemble a human embryo in its first days of development. These structures, called blastoids, offer scientists a way to [...]

In the field of radiology, AI models have the potential to improve imaging analysis, speed up diagnoses and catch errors that might otherwise be missed. But the vast majority of these models are trained on adult data and don't translate well to infants and children, keeping these advances out of reach of neonatal and pediatric care.

A new knowledge distillation framework compresses three large neural networks into a 6.97 MB model that classifies rice diseases, localizes infections, and quantifies severity on a budget smartphone in under 15 milliseconds.

NASHVILLE, Tenn. — Liver transplantation yielded favorable short- and intermediate-term outcomes for patients with unresectable colorectal liver metastases confined to the liver, according to a study presented at ACG Annual Meeting.Additionally, incidence of graft-related mortality after transplant was low, with most deaths among transplant recipients related to malignancy.“Liver transplantation for unresectable colorectal liver metastases is an emerging indication, but its role in the United States remains highly selective and continues to evolve,” Ragesh B. Thandassery, MD, a hepatologist

A new European report says AI can improve care, but only if doctors stay in charge and high-risk systems remain under strict human oversight.

The investment will expand continuous cover forestry across Europe, and represents SLM Silva Fund II's first and final close. The post SLM Partners secures $167m from Dutch pension investor to regenerate forests appeared first on AgFunderNews.

A new review charts how stem cell-derived human microglia, brain organoids and chimeric mice are overcoming the genetic and environmental limits of traditional models to transform the study of neuroimmune disease.

Researchers have built AMIFound, a single foundation model trained on 3.76 million image pairs that restores and enhances medical images across seven modalities, outperforming 38 specialist baselines and improving downstream disease detection and cancer prognosis.

UC Davis Health research has found that people who received a kidney from a living donor with a history of smoking face a higher risk of transplant failure. Transplant failure, known as graft loss, occurs when the transplanted kidney permanently stops working. The highest risk was among patients whose donors had a substantial smoking history.

It is always good to see a diversification in non-profit efforts to advance the state of research and development in the matter of treating aging as a medical condition. Given the vast costs imposed by aging, humanitarian and fiscal, we stand a long way removed from the deployment of an adequate amount of funding for aging research. New advocates and new organizations are very welcome, to add to existing efforts to induce more funding for necessary research, and more capital into the longevity industry. We started Second Century Foundation to fulfill our childhood dream of a world where no one has to suffer or die from aging. Second Century Foundation is a 501(c)(3) private operating foundation focused on accelerating breakthroughs in human longevity. Much of […]

Cells become senescent in response to various forms of damage and stress, including the stress induced by reaching the Hayflick limit on replication. This was first described in the context of replicative senescence in cell cultures, and from there cellular senescence became a topic of interest in cancer research. In more recent years, the accumulation of senescent cells in aged tissues was demonstrated to be an important contribution to degenerative aging, and a small industry of biotech companies has emerged to develop a variety of therapies to either selectively destroy or modulate the behavior of senescent cells. The history of cellular senescence is, in many ways, a history of expanding biological complexity. What began as an observation of finite proliferative capacity in cultured cells has […]

An NYU Abu Dhabi study in EMBO Reports shows that a single cancer-causing gene drives liver cells into distinct senescent states, some permanently tumor-suppressive and others reversible, with major implications for senolytic cancer therapy.

A kidney transplant patient developed HLH, a rare immune overreaction, from a cat-scratch bacterium. Gene sequencing finally exposed the culprit.

An optogenetic gene therapy used with special goggles improved light sensitivity in 7 of 10 people with advanced retinitis pigmentosa in a small trial.

Researchers have built an LLM-based conversational virtual patient with an automated evaluation engine that lets medical students practice clinical interviews and receive instant feedback, earning strong usability scores in an initial validation study.

Patients are using AI to analyse hospital bills and dispute possible errors, but experts warn the technology may increase costs, misclassify charges and expose consumers to privacy and financial risks.

A meta-analysis of 40 studies covering 12,769 patients shows that radiomics-based models combining CT image features with clinical data can predict high-risk pathological features in gastric cancer with pooled AUCs of up to 0.90, though multicenter external validation is still needed.

Researchers have developed Adaptive-CGAN, a generative AI framework that produces realistic synthetic chest X-rays, lifts diagnostic accuracy to 99.60 percent, and cuts training carbon emissions through optimized cloud deployment.

In a phase 1 study of 10 adults with advanced retinitis pigmentosa, researchers found that optogenetic gene therapy combined with light-stimulating goggles was generally well tolerated, although one participant experienced a severe but transient ocular adverse event. Seven participants showed improved light sensitivity, while four of eight who completed behavioral testing demonstrated modest gains in visual function, providing preliminary evidence of partial vision restoration that requires confirmation in larger controlled trials.

The first Europe-wide expert working group on Artificial Intelligence in mental health launches today to the ECNP congress in Munich, where the group will host an open discussion, setting out the potential, the problems, and possible directions for AI in psychiatry and neuroscience.

The first Europe-wide expert working group on artificial intelligence in mental health has launched at the ECNP Congress in Munich with a three-year plan to map, evaluate and guide the regulation of AI across European psychiatry.

Johns Hopkins University engineers have created robots the size of a pencil tip intended to travel through the body to deliver medicine to infections inside a beating heart.

Northwestern Medicine scientists have identified a stem-like state in small-cell lung cancer that distinguishes a group of patients with exceptionally poor outcomes following chemoimmunotherapy, according to a study published in Cell Reports Medicine.

Apple TV today announced “Heart,” an original eight-episode true-crime podcast involving two men linked by a donated heart and the same terrible demise. Here are the details. more…

Women who stay on aromatase inhibitors for 5 years have higher risks of hypertension, dyslipidemia, and diabetes vs their non-adherent counterparts. Yet their mortality rate is lower.

A Harvard-led study of more than 1,300 pregnancies found that a Mediterranean-style prenatal diet and regular seafood consumption were associated with significantly lower infant risk of colic and eczema.

Cancer incidence after solid organ transplant varies significantly based on transplant and malignancy type.A study of more than 620,000 patients who received heart, kidney, liver or lung transplant showed that patients who had lung transplants had the greatest incidence rates for solid tumors, nonmelanoma skin cancer and posttransplant lymphoproliferative disorder (PTLD).Additionally, bladder, colorectal, genital and lung cancer incidence increased over time, whereas melanoma, thyroid cancer and PTLD rates dropped after high early incidence.“This is something we should be more observant of,

If you are planning to buy a Shelby Mustang, there are a few key things to look out for to ensure you are not getting a clone or fake car for a premium price.

Cells become senescent in response to stress and damage, in response to tissue injury, but most commonly upon reaching the Hayflick limit to replication. A senescent cell ceases to replicate, grows in size, and generates a potent mix of pro-growth, pro-inflammatory signals. Senescent cells are created throughout life in tissues throughout the body, but an established population of lingering senescent cells only begins to accumulate in later life. In youth, the immune system efficiently clears senescent cells, allowing senescence to be a beneficial state in the coordination of regeneration and in drawing the attention of the immune system to potentially cancerous cells. In later life, the immune system falters in this task. An established population of senescent cells that generates signaling constantly, even in relatively […]

Donor organs are exceedingly scarce, so much so that one in five people on the waiting list for a heart transplant in the U.S. dies or is removed from the list before receiving a transplant.

Researchers report the first CRISPR/Cas12a editing of sugarcane, showing that co-expressing the mTREX2 exonuclease boosts large deletions seven-fold and enables efficient multiallelic editing of the lw1 gene in the crop's highly polyploid genome.

A fusion of CT-based habitat radiomics and 3D deep learning predicted the hidden STAS invasion pattern in early-stage lung adenocarcinoma with an AUC of 0.824 before surgery.

A new review in Current Research in Food Science details how artificial intelligence, CRISPR gene editing and RNA interference are converging to cut the 25 to 50 percent of fruits and vegetables lost after harvest each year.

Donor organs are exceedingly scarce, so much so that one in five people on the waiting list for a heart transplant in the U.S. dies or is removed from the list before receiving a transplant.

InvestorPlace - Stock Market News, Stock Advice & Trading Tips Neuralink is private, but Butterfly Network and Quantum-Si offer two very different public-market angles on brain-computer interfaces. The post 2 Brain-Computer Interface Stocks to Watch While Neuralink Stays Private appeared first on InvestorPlace.

Google has taken a stake in Flo Health, the period-tracking app, the companies said on Monday. The multi-year deal will bring women’s health data into Google’s wearables and coaching. They did not disclose the size of the investment. From early 2027, users will be able to sync Flo with the Google Health app, Engadget reported. Fitbit readings such as […] This story continues at The Next Web

Google's Sleek New Fitbit Edge Is Packed With Health Features And A Replaceable Battery  EngadgetGoogle Fitbit Edge: Our all-new smartest fitness tracker ever  blog.googleGoogle Debuts $180 Fitbit Edge Tracker in Continued Health Push  Bloomberg.comGoogle announces the Fitbit Edge, a middle ground between Pixel Watch 5 and Fitbit Air  Ars TechnicaThe Fitbit Edge is for folks who don’t want to go totally screenless  The Verge

Google's Sleek New Fitbit Edge Is Packed With Health Features And A Replaceable Battery  EngadgetGoogle Fitbit Edge: Our all-new smartest fitness tracker ever  blog.googleGoogle Debuts $180 Fitbit Edge Tracker in Continued Health Push  Bloomberg.comGoogle announces the Fitbit Edge, a middle ground between Pixel Watch 5 and Fitbit Air  Ars TechnicaThe Fitbit Edge is for folks who don’t want to go totally screenless  The Verge