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Medical artificial intelligence is often presented as a story about algorithms: larger datasets, faster processors and increasingly sophisticated models that can detect disease, predict clinical deterioration or recommend treatments. But a systematic review of 330 research papers suggests that the success of medical AI may depend on a less celebrated component—the people expected to use […]

Drug diversion software monitors millions of hospital transactions, but the failure point is usually staffing rather than the algorithm.

A fish fin can lose a substantial portion of its skeletal structure and still rebuild itself to remarkably precise proportions. A new study of zebrafish regeneration suggests that this apparent biological memory is encoded not in a single permanent blueprint, but in a dynamic chemical signal that measures how much tissue has been removed and […]

The adult human brain has limited capacity to repair or regenerate neurons lost to Alzheimer's disease, the most common type of dementia.

A small pilot study from Thailand suggests that adolescents who undergo hematopoietic stem cell transplantation may develop a strong and persistent antibody response after receiving two doses of the human papillomavirus vaccine, challenging the assumption that three doses are always necessary for this medically vulnerable group. The findings, published in BMC Infectious Diseases, offer early […]

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A Nature Medicine analysis ran 16 epigenetic clocks across 51 longevity studies. Most interventions moved nothing, and senolytics disagreed.

On the forearms of those working in the laboratory at the University of Oslo, one thing stands out: mysterious round or cross-shaped scars on the skin. Here, researchers need skin cells, and they themselves step up in the service of research. The skin cells are allowed to grow and multiply, and then the work begins to reprogram them into so-called iPS cells, induced pluripotent stem cells. These are cells that can divide indefinitely and give rise to all types of specialized cells in the body. They can, for example, become muscle, blood or nerve cells.

Revolution's lifesaving pancreatic cancer drug wins speedy FDA approval  ReutersF.D.A. Approves the Drug Daraxonrasib That’s Poised to Transform Pancreatic Cancer  The New York TimesFDA approves life-extending pancreatic cancer drug Rasonque  USA TodayA major RAS drug milestone could spur interest in rival assets  AxiosFDA Approves RevMed’s Breakthrough Pill for Pancreatic Cancer  Bloomberg.com

Revolution's lifesaving pancreatic cancer drug wins speedy FDA approval  ReutersF.D.A. Approves the Drug Daraxonrasib That’s Poised to Transform Pancreatic Cancer  The New York TimesFDA approves life-extending pancreatic cancer drug Rasonque  USA TodayA major RAS drug milestone could spur interest in rival assets  AxiosFDA Approves RevMed’s Breakthrough Pill for Pancreatic Cancer  Bloomberg.com

A Master Switch in Salmonella May Link Sticky Biofilms to Bacterial “Social” Signals A gene regulator best known for helping Salmonella build its tough, adhesive biofilms may also influence how the pathogen interprets chemical messages from neighboring bacteria. In a study published in Molecular Genetics and Genomics, researchers report that CsgD sits at a previously […]

A GP surgery in South Yorkshire has withdrawn an AI receptionist after a woman recovering from a stroke could not make it understand her and moved to another practice. The NHS Accessible Information Standard has required practices to identify and meet patients’ communication needs since 2016. A woman recovering from a stroke could not get […] This story continues at The Next Web

Adults with at least one parent who reached age 100 lived longer and had substantially lower risks of cardiovascular disease and hypertension than people whose parents had shorter lifespans, according to a study published today in JAMA Network Open.

A new study led by researchers at Johns Hopkins Medicine found that a simple urine test performed on deceased kidney donors could help doctors make better transplant decisions, giving more people access to successful kidney transplants while reducing the number of deceased donor kidneys that go unused.

Pancreatic cancer is considered one of the hardest to treat and most serious forms of cancer

Researchers have developed a new way to study CLN3-Batten disease, a rare inherited condition that causes early vision loss in children followed by progressive neurological decline. Their findings offer new insight into how the disease begins and point to a promising path for treatment.

FDA Approves Drug for Pancreatic Cancer in Incredible Moment for Deadly Disease  WSJF.D.A. Approves Drug Poised to Transform Care for Pancreatic Cancer  The New York TimesRevolution Medicines gets FDA nod for targeted pancreatic cancer drug  CNNFDA approves breakthrough drug to treat advanced pancreatic cancer  ABC News - Breaking News, Latest News and VideosFDA approves first-of-a-kind pancreatic cancer drug trialed at Dana-Farber in Boston  WCVB

FDA Approves Drug for Pancreatic Cancer in Incredible Moment for Deadly Disease  WSJF.D.A. Approves Drug Poised to Transform Care for Pancreatic Cancer  The New York TimesRevolution Medicines gets FDA nod for targeted pancreatic cancer drug  CNNFDA approves breakthrough drug to treat advanced pancreatic cancer  ABC News - Breaking News, Latest News and VideosFDA approves first-of-a-kind pancreatic cancer drug trialed at Dana-Farber in Boston  WCVB

In this video interview, Sunir J. Garg, MD, FACS, FASRS, discussed 2-year results of the phase 2 LUNA study on ixoberogene soroparvovec, an intravitreal gene therapy from Adverum Biotechnologies for wet age-related macular degeneration.The results were presented at the American Society of Retina Specialists annual meeting.“Everybody received one injection, and it reduced the need for supplemental treatment by 90% over 2 years while maintaining stable visual acuity as well as stable, and really quite good, retinal anatomy,” Garg, chief of the retina service at Wills Eye Hospital and professor

Hormone replacement therapy (HRT) may reduce the risk of dementia, particularly for certain groups of women - according to a study from the University of East Anglia and the University of Exeter.

A research team from Tel Aviv University and the Leibniz Institute of Polymer Research Dresden (IPF), led by Ayala Lampel and Carsten Werner, has developed a peptide-glycosaminoglycan hydrogel system that creates a programmable niche for hematopoietic stem and progenitor cells (HSPCs). The system mimics key biochemical and mechanical cues of the bone marrow microenvironment, enabling researchers to investigate how these signals influence stem cell behavior.

Bats are anomalies in the mammalian world—they fly, have long lifespans and rarely get cancer. Scientists now suspect the bat immune system enables them to live longer without disease, according to a new study published today in Nature.

Aurora Therapeutics, the first company that focused on creating bespoke gene editing treatments, has laid off several staff members and stopped its lead program. The company was using CRISPR base editing to fix mutations that ...

Scientists found those who had used hormone replacement therapy were 10% less likely to be diagnosed with dementia Hormone replacement therapy may reduce the risk of dementia, a study has found. Scientists tracked more than 180,000 postmenopausal women in the UK in the largest study of its kind. They found that those who had used HRT were 10% less likely to develop any type of dementia and 16% less likely to be diagnosed with Alzheimer’s, the most common form, compared with those who had never used it. Continue reading...

Moderate calorie restriction lowered an immune protein called C3 that appears to help drive chronic inflammation as the body ages. Blocking the same protein reduced age related inflammation in mice, raising the possibility that future treatments could mimic some benefits of calorie restriction without severe dieting.

Researchers have analyzed 1 million health-related Reddit threads to build an AI platform that can quickly identify mental health concerns in hopes that the findings will help fast-track and better personalize care.

High-sensitivity tracking of a high-risk mutation may help identify risk for relapse in patients with acute myeloid leukemia around the time of allogeneic transplant.

Director Baek Jong-yeol teamed up with actor Koo Kyo-hwan to adapt the popular webtoon "Reawakened Man" into the action film "Reawaken Man: The Red." The director said he focused on reshaping the original comic's premise into a fast-paced action film about an unemployed youth who gains the ability to revive after death. "The original webtoon has a very famous premise about an ordinary person acquiring a completely extraordinary power," Baek, a former commercial and music video director who previously directed "The Beauty Inside" (2015) and Netflix's "Believer 2" (2023), said Wednesday. "My main focus was figuring out how to effectively reconstruct this narrative within the short runtime of a film medium." "Reawaken Man: The Red" follows Seok-hwan (Koo), an unemployed young man. After dying, he realizes he possesses a supernatural ability to revive 72 hours after death, which makes him the target of a mysterious group. Koo continues his impressive box-office streak following his lead

Robot-assisted knee replacement surgery is more precise than surgery performed without robotic assistance, but it does not currently improve patient outcomes. A robotic arm can help surgeons position a knee replacement more precisely, but that extra accuracy does not necessarily mean patients recover better. Results from RACER-Knee, the world’s largest clinical trial of its kind, [...]

Dolly Parton's life in her own words reveals her Smoky Mountains childhood, faith, marriage to Carl Dean and her views on aging and what comes after.

Artificial intelligence (AI)-based analysis of facial videos can rapidly and accurately detect undiagnosed high blood pressure and diabetes, according to a study that will be presented at ESC Congress 2026.

Hormone replacement therapy (HRT) may reduce the risk of dementia, particularly for certain groups of women—according to a study from the University of East Anglia and the University of Exeter.

MindRank, a Hangzhou drug developer built around AI, says its lead candidate went from programme initiation to Phase III trials in roughly four and a half years on about $23mn of cumulative research spending. If that holds up, it is the most concrete answer yet to a question the sector has been asking loudly and […] This story continues at The Next Web

arXiv:2608.24885v1 Announce Type: new Abstract: Action-conditioned world models are increasingly used as learned simulators for policy evaluation and improvement, yet their effectiveness rests on an unverified assumption: generated futures faithfully reflect arbitrary valid actions. Existing benchmarks are typically confined to expert demonstrations, leaving off-expert action following inadequately evaluated. To address this gap, we introduce WorldEcho, which probes action following over a broader action distribution using visual integrity and SE(3) trajectory alignment. Our diagnosis shows that current world models reasonably execute expert actions but struggle with diverse off-expert trajectories, either ignoring the commanded actions or producing visually invalid rollouts. We further propose WorldSync, which strengthens action following along three complementary axes: distributional coverage, representational grounding, and intervention-effect alignment. It broadens the training

arXiv:2608.24461v1 Announce Type: new Abstract: System prompts can be extracted from commercial LLMs with over 80\% success and redeployed at zero cost, yet a prompt owner has no way to verify whether a suspected deployment is a clone. We propose Black-Box Behavioral Fingerprinting (BBF): the prompt owner registers a behavioral signature from model outputs and later tests whether a suspect deployment matches that signature more closely than an unrelated baseline. BBF requires only black-box API access. Through a large-scale study (4 model families, 8 benchmarks, 288{,}000 responses), we find that prompt choice explains 24.4\% of output variance and same-model detection reaches AUC 0.876. Cross-model performance is bounded by detector identity, with off-diagonal AUC ranging from 0.845 (Claude as detector) down to 0.665 (Qwen) and overall mean 0.725. BBF resists non-adaptive prompt paraphrasing (AUC $\geq 0.889$) and is robust to imperfect extraction, but a single-sentence formal-tone

arXiv:2608.24338v1 Announce Type: new Abstract: Inference-time decoding methods improve LLM reasoning by exploring multiple candidate trajectories, yet treat each trajectory as atomic: either retaining it whole or discarding it irreversibly. This wastes computation on partially promising candidates whose high-quality prefixes are abandoned alongside degraded suffixes. We introduce Selective Regenerative Decoding (SRD), which routes each candidate to discard, keep, or refine only the degraded portion of the suffix while preserving the useful prefix of borderline candidates, without requiring a larger target model. Under mild assumptions, SRD achieves a provable 1.28-to-1.36-fold gain in sample efficiency over rejection sampling with strictly higher expected trajectory quality, with the gain growing as the candidate pool grows. Across MATH500, GPQA Diamond, HotpotQA, and AlpacaEval with multiple generation-reward model pairs, SRD matches Best-of-N accuracy with substantially fewer

Pew Research Center: Survey: 28% of Americans use AI chatbots to get health information quickly, 25% to figure out symptom causes, and 22% to get health information at no cost  —  Reasons include making diagnoses and learning more about lab results or treatments.  Nearly all chatbot health users find this AI information helpful

Vulvovaginal candidiasis, a common fungal infection affecting women of reproductive age, may be facing a new kind of biological countermeasure. Researchers from institutions in Iran and Austria report that a cell-free preparation derived from bone marrow mesenchymal stem cells showed antifungal and antibiofilm activity against clinical Candida isolates, including strains classified as resistant to fluconazole, […]

Researchers developed a SuperLearner framework that combines established epigenetic clocks with machine learning to compare DNA methylation-based aging in residents of Costa Rica’s Nicoya Blue Zone with other Costa Ricans. Initial calibration suggested a modest younger epigenetic age among Nicoyans, but accounting more closely for age distribution substantially reduced the apparent advantage, highlighting the importance of population-specific calibration in longevity research.

Harvard researchers cultured cortical organoids for the past five years, then found that old cells skip developmental steps they had already completed.

LANSING, Mich. — The Michigan Department of Agriculture and Rural Development (MDARD) has announced an innovative initiative to help beginning, small and medium-sized dairy farms boost profitability and improve resiliency through dairy grazing. Dairy grazing is the practice of having dairy cows primarily eat fresh grass in managed pastures during the warmer months instead of […] The post MDARD Expands Regenerative Agriculture Work Through Dairy Grazing appeared first on Morning Ag Clips.

A new case report describes a “femoral-free” configuration for ambulatory venoarterial extracorporeal membrane oxygenation (V-A ECMO), a form of life support that can maintain circulation and oxygen delivery while allowing critically ill patients to participate in active rehabilitation. The technique, reported by surgeons at Keimyung University Dongsan Medical Center in South Korea, uses the right […]

Patients with sickle cell disease are often hesitant to undergo transformative gene therapy—the current lengthy process requires multiple hospital visits to collect enough stem cells. Researchers from Boston Children's Hospital have helped smooth the road to gene therapy with a new approach that collects enough of the patient's stem cells in a single hospital admission for most patients, improving the turnaround time for genetically altering and infusing the cells back into the patient. The long-term follow-up results of the first-in-human phase I pilot clinical trial were recently published in Blood.

FDA placed REGENXBIO's RGX-121 on clinical hold after spine MRIs showed nodules or cysts in five Hunter syndrome trial participants.

A dual stem cell scaffold improved vision and eye surface scores in a small first-in-human trial for aniridia-related keratopathy. For people with ARK (aniridia-related keratopathy), progressive damage to the eye’s surface can gradually cloud the cornea and severely reduce vision. In a first-in-human clinical trial at Moorfields Eye Hospital and University College London (UCL), a [...]

Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), and Tianjin Medical University General Hospital have developed a bioinspired lipid nanoparticle (LNP) that can deliver gene-editing machinery to the liver and reduce low-density lipoprotein (LDL) cholesterol, commonly known as "bad" cholesterol. The nanoparticles reduced LDL and total cholesterol by more than 20% after two doses, while showing fewer signs of inflammation and toxicity than comparator formulations. The findings were published in the Journal of Controlled Release.

A new model developed by researchers at Kumamoto University and collaborators from Tohoku University and Kyushu University could advance research into preeclampsia and other pregnancy complications. The team has developed a robust method for producing human trophoblast stem cells (hTSCs) from late-gestation placentas, opening a new avenue for studying pregnancy complications using patient-derived cells. The work is published in the Proceedings of the National Academy of Sciences.

Stem cells possess the unique ability to self-renew and transform into different types of cells. For example, rare hematopoietic stem cells found in bone marrow can become any type of blood cell. Throughout life, they can produce new blood cells to replace those lost because of infection, bleeding or chemotherapy.

Researchers at NYU Abu Dhabi have developed BRIDGE (Biodegradable aRchitected Internal DrainaGE), a biodegradable, 3D-printed gastric stent that could improve treatment for gastric leaks, a serious complication following weight-loss surgery. By combining an advanced internal lattice design with biodegradable materials, the new device more than doubles drainage performance while potentially eliminating the need for a second procedure to remove the stent after healing.

Bladder cancer claims 220,000 lives globally each year, with symptoms sometimes mistaken for other conditions such as kidney stones. Now researchers have developed an artificial intelligence system that can identify bladder cancer patients up to five years before their official diagnosis, potentially revolutionizing screening for the disease.

TUESDAY, Aug. 25, 2026 — Knee replacement patients do just as well with regular old “sawbones” surgery as they do with cutting-edge robot-assisted procedures, a new clinical trial has found.Robot-assisted knee replacement surgery is more precise...

Precisely editing the dominant MYB10-1B gene copy converted red strawberries into stable white fruit and demonstrated a targeted strategy for modifying polyploid crops. A strawberry’s familiar red color depends on a complicated genetic system. Cultivated strawberries carry eight sets of chromosomes, so many genes occur in several closely related copies, making it difficult to change [...]

One minute and 49 seconds, that was the median time a machine needed to read a patient’s arm, choose a vein, insert a needle, fill the tubes, and withdraw, across the Dutch clinical trial that carried it towards regulators. A phlebotomist working carefully takes roughly five minutes, by the company’s own reckoning. Nothing about the […] This story continues at The Next Web

A new analysis of approximately 2.3 million people has examined whether following a Mediterranean-style diet is associated with a lower risk of pancreatic cancer, one of the most difficult cancers to detect and treat. Drawing on the Pooling Project of Prospective Studies of Diet and Cancer, the investigation brings together data from multiple large-scale studies […]

Researchers from the University of Turku in Finland and Gustave Roussy Institute in France have discovered a molecular mechanism that regulates whether the cells of an aggressive colorectal cancer are conventional or inverted when they spread in the body.

Epigenetic clocks can give ‘a vague concept of aging,’ but researchers are progressing to organ-specific techniques that provide actionable, medically meaningful data.

A phase 3 trial evaluates a low-dose ruxolitinib-based regimen for graft-vs-host disease prophylaxis among patients undergoing haploidentical hematopoietic stem-cell transplantation.

A new study is drawing attention to a possible metabolic vulnerability in breast cancer stem cells: the mitochondrial DNA maintenance enzyme polymerase gamma, or POLG. Published in Aging on August 8, 2026, the pilot study reports that disrupting either component of the POLG system weakened mitochondrial activity and reduced stem-cell-like behaviors in several breast cancer […]

Diabetic foot ulcers are among the most stubborn complications of diabetes, combining poor circulation, persistent inflammation, microbial risk and a profound failure of tissue repair. A new study published in Military Medical Research describes a bioengineered strategy designed to address several of these problems at once. The researchers developed a treatment that combines trace-element-programmed exosomes […]

​Transplant medicine still depends on a limited supply of donor organs, while many retrieved grafts are discarded because ischemia, cold storage, and reperfusion can rapidly damage their cells.

A gene therapy designed to replace a damaged or missing copy of the alpha protein kinase 3 gene has restored cardiac function in mouse and human models of cardiomyopathy, according to a study published in Nature Cardiovascular Research. The work focuses on ALPK3, a gene whose disruption can interfere with the formation, organization and performance […]

The FDA grants accelerated approval for the innovative, one-time gene therapy Genglycos to treat the rare disease GSDIa in children aged 8 years and older and adults.

Han, Cho, Takahashi and colleagues have reported a potential new way to strengthen cancer immunotherapy from inside the gut: an orally administered nanotechnology system designed to deliver a metabolite produced by intestinal microbes. According to the study, published in Nature Nanotechnology, this approach enhances the “stemness” of T cells, a biological property associated with long-term […]

arXiv:2608.22383v1 Announce Type: new Abstract: Current code clone detection (CCD) methods rely on fixed, language-specific graph representations like abstract syntax trees (ASTs) or program dependency graphs (PDGs). Because functionally identical code fragments can yield wildly different structures, these rigid graphs produce non-discriminative spectra that perform close to chance. To address this, we propose SPECTRA-Siam, a Siamese latent graph learning network that learns a latent space such that the graph's spectrum serves as a discriminative signature of code functionality by optimizing downstream CCD performance. Given a fragment's AST and data-dependencies, SPECTRA-Siam induces a fixed-size weighted latent graph through soft slot assignment and multi-head attention, and extracts a multi-scale spectral representation from its normalized Laplacian. Mapping all fragments into this shared space yields comparable spectra across programming languages. Experiments on BigCloneBench,

arXiv:2608.22108v1 Announce Type: new Abstract: Breast Cancer Multidisciplinary Team (MDT) meetings manage increasingly complex cases under considerable time pressure, and documentation requirements can reduce clinical efficiency and decision quality. Existing AI based MDT workflows rely on cloud-based processing, limiting their use because patient discussions contain identifiable information. We developed a fully on-device AI pipeline using open-source Automatic Speech Recognition (ASR) and Large Language Models (LLMs) that transcribes breast cancer MDT discussions, structures clinical information, and generates treatment recommendations using retrieval-augmented generation (RAG) grounded in National Institute for Health and Care Excellence (NICE) guidance. The pipeline runs on a single NVIDIA Jetson AGX Orin, ensuring that patient audio, transcripts, and outputs remain within institutional infrastructure. Evaluation included two recorded simulated MDT discussions, ten clinically

arXiv:2608.21810v1 Announce Type: new Abstract: Clinical decision-making is inherently experience-driven: physicians progressively refine their reasoning by synthesizing patient history, multimodal observations, and prior diagnostic experiences across interactions. In contrast, current multimodal large language model (MLLM)-based medical AI agents largely operate as stateless inference systems, generating decisions independently for each interaction without retaining or internalizing experiential knowledge. This discrepancy limits their ability to progressively improve reasoning reliability through usage and adapt to longitudinal patient contexts in real-world clinical workflows. In this study, we propose Medical Structured Multimodal Memory (MSM-Mem), an agentic memory framework that enables medical AI agents to evolve through accumulated clinical experiences. MSM-Mem organizes heterogeneous clinical experiences into semantic, episodic, and visual memory and incrementally updates

A familiar cell-cycle protein may be helping aging cells broadcast inflammatory signals throughout the body, according to a new study published in Nature Aging. Researchers report that cyclin D1, or CCND1, and its partner enzyme CDK6 remain unusually active in senescent cells even after those cells have permanently stopped dividing. Rather than being a harmless […]

Researchers analyzing 51 longitudinal intervention studies found that reliable generation 2+ DNA methylation biomarkers, particularly those predicting mortality or pace of aging, were the most responsive to interventions aimed at longevity or healthspan. Pharmacological and lifestyle interventions produced the strongest biomarker changes, but the authors cautioned that responsiveness does not yet establish these measures as validated surrogate endpoints for slower aging or longer life.

A heart transplant can restore circulation, reverse advanced heart failure and give patients years of life, but the new organ remains under constant surveillance by the immune system. The recipient’s body recognizes the transplanted heart as biologically foreign, creating the possibility of cardiac allograft rejection. Clinicians currently rely on tissue biopsies, imaging, blood tests and […]

Tropical forests may be able to return naturally across millions of square kilometres of degraded land, offering a powerful but unevenly distributed opportunity to fight climate change and slow biodiversity loss, according to a new global analysis. The study, published in Nature Ecology & Evolution, identifies where natural forest regeneration could deliver the greatest ecological […]

Stem cells possess the unique ability to self-renew and transform into different types of cells. For example, rare hematopoietic stem cells found in bone marrow can become any type of blood cell.

Twenty years after scientists first demonstrated that a mature cell could be pushed backward into a stem-cell-like state, induced pluripotent stem cells are entering a new phase—one defined not only by the ability to reset cellular identity, but also by the growing capacity to control, observe, and safely deploy that transformation. An editorial published in […]

CHA Biotech has secured government backing for a three-and-a-half-year research project aimed at pushing its cell and gene therapy platforms toward clinical development, with 31.5 billion won ($22.7 million) in funding. The biotechnology company said Tuesday that it was selected for a follow-up research and development project under the 2026 K-HERO Development and Support Program, led by the Ministry of Science and ICT and administered by the Korea Industrial Technology Association. The program supports corporate research centers working on national strategic technologies, with the goal of developing core technologies and turning them into commercial products. CHA Biotech will use the funding to develop and commercialize two platforms, CHAMS, a standardized source-cell platform based on mesenchymal stem cells, and CHAGE, which uses therapeutic genes to enhance cell function. The company said it plans to combine the platforms into a development system that can be applied across a range

Sepsis can turn the immune system’s emergency response into a source of widespread tissue damage. When infection triggers an uncontrolled inflammatory cascade, the lungs are among the first organs to suffer. Blood vessels become leaky, immune cells accumulate in lung tissue, and the air sacs responsible for oxygen exchange can fill with fluid. This condition, […]

Senescent cells accumulate with age throughout the body, either in response to forms of damage and stress or on reaching the Hayflick limit on replication. A senescent cell ceases to replicate, grows in size, and secretes a potent mix of pro-growth, pro-inflammatory signals. In youth, the immune system efficiently clears senescent cells, but with age this clearance falters. Like most of the progression of degenerative aging, the accumulation of senescent cells with age is nonlinear. This is in part because the decline of the immune system accelerates in later life, but it is also the case that the signaling generated by senescent cells can induce nearby cells to also become senescent. Thus senescent cells emerge at an accelerating pace as their numbers grow. In today's […]

Adolescents Are Turning to AI Chatbots for Mental Health Conversations, New Study Examines Artificial intelligence chatbots are becoming an unexpected part of the mental health landscape for adolescents, and a new study is examining how frequently young people use these systems to discuss emotional and psychological concerns. The cross-sectional research, published in JAMA Network Open, […]

Regenxbio said it no longer expects to file for FDA approval of its Hunter syndrome gene therapy in the near future after the program was slapped with its second clinical hold this year. The company ...

What we eat plays a vital role in maintaining a healthy lifestyle. A well-balanced meal rich in essential micronutrients not only fuels the body but may also help protect against metabolic and cardiovascular diseases. There is another question worth asking: Does when we eat matter just as much as what we eat?

AI platform iGenRARE could help doctors diagnose rare diseases by connecting medical clues, with researchers reporting up to 91% accuracy.

Both too little and too much sleep may be linked to faster aging throughout the body. Researchers analyzing 23 biological aging clocks found the lowest aging levels among people sleeping about 6.4 to 7.8 hours per day. Short or long sleep was also associated with numerous conditions affecting the brain, heart, lungs, metabolism, and digestive system.

Surgery remains the primary curative treatment for gastric cancer, with laparoscopic gastrectomy (LG) established as a standard minimally invasive approach. While LG offers faster recovery than open surgery, it remains technically demanding because surgeons must operate within a confined space using rigid instruments that can amplify hand tremors.

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Surgery remains the primary curative treatment for gastric cancer, with laparoscopic gastrectomy (LG) established as a standard minimally invasive approach.

A nationwide study in Japan has found that robotic gastrectomy may provide several measurable advantages over conventional laparoscopic surgery for people undergoing treatment for gastric cancer. The analysis, based on nearly 23,000 matched surgical cases, associated robotic procedures with lower blood loss, fewer conversions to open surgery, reduced infection risk in some patients, and shorter […]

Maintenance therapy is linked to longer overall survival after first-line bevacizumab-based combination chemotherapy in patients with metastatic colorectal cancer, a study finds.

Long‑term outcomes after liver transplantation remain hampered by complications linked to intensive immunosuppression—infections, cardiovascular events, kidney dysfunction, and metabolic disorders affect 10% to 40% of recipients.

The various mitochondrial protein complexes are the building blocks of the electron transport chain, the complicated mechanism inside mitochondria that generates adenosine triphosphate (ATP), the chemical energy store molecule used to power cell activities. Nothing in a cell is simple, and the mitochondrial complexes do not operate neatly in isolation from one another. They drift in and out of supercomplex arrangements of multiple complexes, and it turns out that this supercomplex activity is important to mitochondrial function, and thus to the pace of aging. Researchers recently demonstrated that aging in mice can be slowed by inducing more supercomplex formation, for example. Here, find a review that covers what is known of the role of supercomplexes in aging and longevity. One of the hallmarks of aging […]

The AMA released a framework insisting that physicians stay central as AI enters care. A JAMA opinion published days earlier argues the reverse.

arXiv:2608.21326v1 Announce Type: new Abstract: Autonomous AI diagnostic agents, systems that analyse patient-specific clinical data and produce diagnostic outputs or triage decisions without mandatory real-time human review, are increasingly deployed across eHealth platforms in sub-Saharan Africa at a pace that has outrun the governance infrastructure needed to oversee them. While significant bodies of work address AI accountability, transparency and explainability in healthcare, existing frameworks are largely clinician-centered and assume regulatory conditions that do not uniformly exist in low-resource settings. A patient-centered analysis of the disparity in patient awareness regarding autonomous agents, which results in a structural accountability gap, is mostly missing from the literature. This paper synthesizes existing research on informed consent, algorithmic accountability, and explainable AI to highlight three distinct challenges introduced by deploying AI agents in the

arXiv:2608.21133v1 Announce Type: new Abstract: Medical image-text data can expose protected health information (PHI) through both visible image content as well as accompanying text, creating a barrier to privacy-preserving medical AI systems. This risk is especially prominent in multimodal systems, where images, questions, reports, and clinical context may enter training, evaluation, or inference pipelines. Existing medical vision-language benchmarks primarily emphasize task utility, while de-identification methods are often evaluated separately from downstream reasoning. We introduce ClinX, an end-to-end multimodal PHI sanitization framework for medical image-text data. ClinX detects visible identifiers with optical character recognition (OCR), constructs binary PHI masks, and applies ClinX-PRISM, a no-skip generative restoration module with privacy-oriented post-processing for burned-in identifier suppression. In parallel, text-side PHI is reduced through progressive

arXiv:2608.21057v1 Announce Type: new Abstract: Agentic large language model (LLM) systems are reshaping scientific workflows in chemistry and drug discovery, but evaluating their open-ended, tool-augmented outputs remains a fundamental bottleneck. Reference-based metrics such as BLEU and ROUGE fail to capture semantic correctness, while expert human evaluation does not scale to the iteration speed these systems demand. The LLM-as-a-Judge paradigm has emerged as a scalable alternative, but existing drug discovery benchmarks deploy LLM judges without validating their alignment with human experts. In this work, we present an LLM-as-a-Judge evaluation framework for ChatInvent, an agentic drug discovery assistant deployed at AstraZeneca, with four contributions. First, we define four output-quality evaluation dimensions---Completeness, Relevancy, Structural Clarity, and Scope Adherence---alongside deterministic Tool Call Correctness checks. Second, we validate the judge through a human

The FDA authorized Aletta, the first standalone robotic blood-draw device. One phlebotomist can oversee three units. What the authorization covers.

AI is increasingly being used across precision oncology to accelerate drug discovery, predict resistance, and guide the design of nanoparticle-based drug-delivery systems. The review highlights AI-guided nanocarriers, adaptive treatment strategies, and multi-omics analysis while emphasizing challenges involving data quality, transparency, generalizability, and regulation.