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09.10.2026
00:48 Bioengineer.org Metabolic Switch in Heart Cells Rewinds Injury Into Regeneration, Study Finds

New research shows that transient inhibition of the mitochondrial enzyme succinate dehydrogenase triggers coordinated metabolic and epigenetic reprogramming across heart cell types, reactivating regenerative programs and suppressing fibrosis after myocardial infarction.

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00:35 Bioengineer.org Living Bone Transplants Slowly Heal Devastating Leg Infections, Long-Term Study Finds

A long-term study of 22 patients shows that vascularized fibular grafting achieved bone healing and infection control in nearly three-quarters of severe infected non-unions of the lower limb, though consolidation often took years and a competing-risk analysis was needed to capture the true timeline.

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08.10.2026
23:54 Bioengineer.org Gut Microbe Transplants May Reverse Immunotherapy Resistance in Liver Cancer

A phase II pilot trial found that a single fecal microbiota transplantation combined with atezolizumab and bevacizumab was safe and produced tumor responses in one third of liver cancer patients whose disease had resisted immunotherapy.

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23:40 Bioengineer.org AI Reads the Microscope: Deep Learning Powers Parasite Diagnosis, But Real-World Tests Lag Behind

A scoping review of 118 studies finds that deep learning models excel at detecting parasites in microscopy images under experimental conditions, but very few have been validated or deployed in real clinical laboratories.

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23:40 Bioengineer.org 3D-Printed Lung Models Help Doctors Plug Dangerous Vessel Tangles

A multi-institution feasibility study found that patient-specific 3D-printed models of pulmonary arteriovenous malformations were successfully fabricated for all cases and helped interventionalists plan embolization procedures and educate patients.

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23:16 Entrepreneur.com He Helped Create Modern AI. Now the ‘Godfather of AI’ Wants an FDA-Style Approval System for It.

His idea is an approval system for AI — but what would it take to get a green light?

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23:00 Technology.org AI Startups Run Virtual Drug Trials to Predict Which Human Studies Will Fail

Simulated Patients Before Real Trials A Copenhagen startup has gone on record predicting that drug trials from Biogen

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22:25 GenEngNews.com The State of AI in Drug Discovery

’s virtual summit returns on November 4 to examine how AI is reshaping R&D timelines and real-world patient translation. From big pharma to AI-natives, this year’s program features the leaders of many of today’s outstanding companies and organizations powering the AI revolution! The post The State of AI in Drug Discovery appeared first on GEN - Genetic Engineering and Biotechnology News.

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21:33 FightAging.org Succinate Dehydrogenase as a Regulator of the Regenerative Capacity of the Heart

The tissues of the mammalian body span a broad range of regenerative capacity, from the highly regenerative liver to the minimal regenerative capabilities of the brain and the heart. We might speculate that the evolutionary road to a reduced capability of regeneration in the central nervous system results need to retain structure that stores memory. The heart incorporates a complex electrical system, and the need to retain the structure of this system may also place constraints on the level of regeneration that can take place following injury. Heart damage, such as that resulting from a heart attack and consequent transient loss of blood supply to regions of the heart, heals poorly, and is typically characterized by fibrosis that is disruptive to heart tissue structure and […]

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20:49 Bioengineer.org Fibronectin found to reprogram immune cells and drive tooth regeneration

Researchers have shown that the matrix protein fibronectin reprograms macrophages in damaged dental pulp into pro-angiogenic cells, enhancing blood vessel formation and regenerating pulp–dentin-like tissue in a preclinical model.

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20:35 Bioengineer.org Healthy Habits Pay Unequal Dividends: Where You Live Shapes How Lifestyles Slow Ageing

A study of more than 155,000 adults across 32 countries finds that the healthy-ageing benefits of good lifestyles vary up to fivefold between nations, depending on economic development, healthcare access, climate resilience, and social conditions.

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19:51 News-Medical.Net 3D printing-inspired technology can improve dosing accuracy for personalized medicines

Technology inspired by 3D printing is already being introduced in hospitals and specialized pharmacies to produce personalized medicines tailored to individual patients.

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19:23 TechRepublic.com Healthleap Raises $38M for AI That Spots Hidden Health Risks in Hospitals

Healthleap raises $38 million to expand AI that analyzes hospital records for overlooked health risks, as questions remain about clinical accuracy and patient care. The post Healthleap Raises $38M for AI That Spots Hidden Health Risks in Hospitals appeared first on TechRepublic.

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19:12 SeekingAlpha.com Editas upgraded at Wells Fargo as Australia approves gene editing trial

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19:07 Bioengineer.org Platinum Chemotherapy, Not PARP Inhibitors, Emerges as the Main Driver of Blood Clone Expansion

New research shows carboplatin drives the expansion of TP53-mutant blood clones far more strongly than PARP inhibitors, while inherited homologous recombination deficiency unexpectedly blunts this expansion.

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18:24 MedicalXpress.com Cervical cancer trial finds similar early recovery results after robot-assisted versus open surgery

In early-stage cervical cancer, radical hysterectomy is an established treatment. The operation can be performed either through open surgery or robot-assisted minimally invasive surgery. Until now, there have been limited data from large randomized studies on differences in complications and recovery between the methods.

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18:01 SeekingAlpha.com Nvidia committing $1B to boost AI, quantum, health in the US

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17:42 Bioengineer.org Anti-ageing drug combo clears senescent cells and reverses liver scarring in first randomized trial

A phase-2 randomized trial shows intermittent dasatinib plus quercetin significantly improved liver fibrosis and resolved MASH in nearly half of treated patients, with single-cell sequencing confirming depletion of senescence and fibrosis signatures.

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17:42 MedicalXpress.com Ancient viral DNA helps embryonic stem cells grow—and cancer hijacks the same switch

Three years ago, George Kassiotis and his team made an unexpected discovery: A specific way of producing a protein called calbindin was found to help cancer cells survive by preventing them from aging. This left Kassiotis, who runs the Crick's Retroviral Immunology Laboratory, confused. Why would a mechanism that boosts cancer growth exist in the first place?

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17:36 ScienceNews.org Gene therapy and special goggles give some blind people limited sight

Optogenetics, recognized by the 2026 medicine Nobel, makes cells respond to light, including eye cells that normally relay signals to the brain.

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15:50 Healio.com Kidney transplant, wait-list rates lower with Medicare Advantage

Kidney transplant and wait-listing rates were lower for beneficiaries with Medicare Advantage vs. traditional Medicare, according to study data published in JAMA.The 21st Century Cures Act, passed in 2021, permitted all individuals with end-stage kidney disease to enroll in Medicare Advantage plans, according to Ankur Shah, MD, MPH, associate professor of medicine at the Warren Alpert Medical School of Brown University, and colleagues. However, data exploring whether Medicare insurance type impacts access to kidney transplant have been limited, the researchers wrote.“Earlier work had shown

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15:49 Bioengineer.org AI That Learns Where to Look: Reinforcement Learning Sharpens Machine Fault Diagnosis

Researchers at Shanghai Jiao Tong University have developed a fault diagnosis framework that uses recurrent attentional reinforcement learning to adaptively search for the most informative temporal fragments in machinery sensor data, achieving 76.4 percent accuracy on rolling bearings and 100 percent on a hydraulic system.

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14:41 Medscape.Com Robotic Surgery: Few Perioperative Gains in Cervical Cancer

A secondary analysis of the RACC trial assesses perioperative safety and early quality of life after robot-assisted vs open radical hysterectomy in patients with early-stage cervical cancer.

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14:27 Bioengineer.org Frozen Testicular Tissue Transplant Offers UK Fertility First for Young Cancer Patients

In a UK first, doctors in Edinburgh have transplanted frozen testicular tissue into a young man left infertile by chemotherapy, in only the second such procedure reported worldwide.

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14:27 Bioengineer.org From Dye to Precision: How Fluorescent Marking Is Reshaping Robotic Lung Cancer Surgery

A new commentary argues that lung nodule localisation is entering a precision era, as stabilised fluorescent matrices aim to solve the diffusion problem that undermines surgical margins in robotic sublobar resection.

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13:49 MedicalDaily.com Nonprofit Hospitals Charging $5,500 or More for Longevity Checkups Face Questions Over Tax Breaks and Charity Care

Tax-exempt hospitals now sell longevity programs from $5,500 to as much as $45,000 a year. Here's what's included, what insurance covers, and what critics ask.

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13:42 Saifood.ca DNA Series: Gene Editing

The DNA Series: This is the last blog in the DNA Series (boo!), and we’re delving into the world of gene editing. For this series, … The post DNA Series: Gene Editing appeared first on SAIFood.

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13:33 Bioengineer.org Million-Dollar Cures: Why Insurance Policy Now Decides Which Children Get Gene Therapy

A new Pediatric Research commentary argues that insurance coverage and reimbursement policy, not the underlying science, now determine which children with rare genetic diseases can access curative gene therapies.

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13:19 News-Medical.Net A New Approach to Preventing Bladder Cancer Recurrence

Innovative techniques using electrical energy to treat bladder cancer may lower recurrence rates and minimize the need for radical surgical interventions.

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12:11 MedicalXpress.com Twin study suggests screen time's link to mental health may be overstated

Shared family factors, such as genes and upbringing, are likely to explain a large part of the link between high screen use and mental health problems in young people. This is according to a new study from Karolinska Institutet published in Nature Human Behaviour.

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11:44 Bioengineer.org AI Learns to Diagnose Grapevine Diseases Like a Plant Pathologist

Researchers in Vietnam have built a hybrid vision-language AI that diagnoses grapevine diseases with 98.7 percent accuracy while explaining its reasoning and resisting the background overfitting that cripples conventional CNNs in real fields.

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11:17 Bioengineer.org Lab-Grown B Cells Reveal Why Immune Defenses Falter in Common Variable Immunodeficiency

Researchers in Madrid have developed an in vitro stimulation model showing that B cells from patients with common variable immunodeficiency can begin activating but fail to sustain antibody production, accompanied by a shift toward immune-inhibitory gene expression and altered cytokine profiles.

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10:37 Arxiv.org CS Hall Effect-Based Tactile Force Detection Sensor for Robot-Assisted Minimally Invasive Surgery

arXiv:2610.10346v1 Announce Type: new Abstract: Robotic minimally invasive surgery has revolutionized surgical practice. However, as the surgeons are mechanically separated from the surgical tools, loss of tactile feedback occurs. We present a compact force sensor with three, millimeter scale sensing elements (taxels) that can be affixed to the grasping face of a robotic surgical tool. The sensor features a miniaturized design using Hall effect sensors and magnets embedded in a deformable elastomer contact layer. Sensor calibration is achieved with a 6 degree of freedom (DoF) parallel robot. Each taxel can detect applied normal and shear forces with average RMSE of 2.133 kPa. The calibrated sensor was validated on phantom and ex vivo porcine tissue, demonstrating tactile sensing during retraction as well as slip. This work introduces a small-scale Hall effect based tactile sensor, enabling sensing for force-sensitive robotic surgical applications.

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10:37 Arxiv.org CS OOM-RL II: Reality Is an Oracle, Not a Debugger Provenance-Constrained Diagnosis in Continually Evolving Agent-Engineered Systems

arXiv:2610.10256v1 Announce Type: new Abstract: Reality may establish that an outcome occurred without identifying which evolving procedure produced it or why. This distinction matters in production ML systems whose code, configuration, and artifacts change while external feedback accumulates. We examine it in a human-directed, agent-engineered quantitative trading system, using oracle to mean an external source of realized outcomes rather than a complete correctness specification. Across one year, the account gained and outperformed a broad market index, while annual alpha was not statistically distinguishable from zero under the main retrospective specification. Retrospectively selected subperiods include adverse relative performance and conditional candidate-level weakness under declared approximate references. Engineering records document changes during the episode, and complete recommendation-to-runtime binding is unavailable. The archive does not establish a common frozen

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10:37 Arxiv.org CS Latent Watermarks under Generative Editing: A Benchmark and Analysis of Detection Survival

arXiv:2610.09702v1 Announce Type: new Abstract: Ordinary prompt-based editing can cause latent watermark detection to fail without explicitly targeting the watermark. We benchmark eight watermark methods against five editors across four generative backbones, four editing strengths, and five semantic categories, with edit-validity and threshold checks. Separating editing from seven subsequent distortions reveals that editing alone primarily distinguishes Tree-Ring, while added distortions expose a broader spectrum of detection survival. Sequential edits reveal a second hidden difference: score separation can decline while detection rates remain near their ceiling. Across methods, standardized clean score separation ($d'$) organizes composite-survival tiers, whereas spatial overlap adds little to predicting edit-only survival beyond clean detectability. Embedding-strength interventions in two methods link higher clean separation to higher post-edit separation. In HSTR, the margin

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10:37 Arxiv.org CS DrugTargetWorld: A Synthetic Biobank for Training and Benchmarking AI Scientists

arXiv:2610.09558v1 Announce Type: new Abstract: Drug target discovery requires distinguishing molecules that causally drive disease from those that are merely associated with it. Training and evaluating AI agents to perform this workflow end-to-end is difficult because real world biobanks lack known causal ground truth and participant-level data is access controlled. We introduce DrugTargetWorld, a framework that procedurally generates simulated biobanks, or "worlds," with known but concealed causal structure. Each world contains genotypes, proteins, health records, outcomes, and synthetic magnetic resonance imaging (MRI) for 54,000 participants. Agents must construct a disease phenotype, identify causal driver proteins, infer the beneficial direction of modulation, and optionally conduct virtual 'wet lab' experiments. We evaluated nine agents in 540 episodes across 20 cardiovascular worlds and three experimental budgets. Opus 5 and GPT-5.6 Sol achieved the highest mean composite

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10:37 Arxiv.org CS BanglaBox: A Phonetically-Balanced Corpus and Data-Efficient Foundation-Model Adaptation for Bangla Text-to-Speech with Zero-Shot Voice Cloning

arXiv:2610.09211v1 Announce Type: new Abstract: We present a recipe for adapting English-pretrained autoregressive TTS foundation models to underrepresented languages, demonstrated on Bangladeshi Bangla. Existing Bangla TTS corpora are small and single-speaker, and to our knowledge no open zero-shot voice-cloning system is available for the Bangladeshi register. We contribute a phonetically- and gender-balanced two-tier Bangladeshi Bangla corpus balanced via a tiered Jensen-Shannon divergence objective over conjunct clusters (juktakkhor), together with three fine-tuning changes: a merge-consistent tokenizer extension, Bangla text normalization, and a prompt-masked dual-loss objective. These changes preserve zero-shot cloning across the language switch. Our BanglaEval protocol applies Wilcoxon signed-rank tests with Bonferroni correction over native-speaker ratings. BanglaBox attains near-natural Naturalness, outperforms commercial and open-source baselines on Naturalness, Speaker

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10:37 Arxiv.org CS Frozen Models, Evolving Expertise: Model-Agnostic Learning from Deployment Experience for Multimodal Medical AI

arXiv:2610.09146v1 Announce Type: new Abstract: Large language models (LLMs) and vision-language models (VLMs) are usually frozen after deployment, so they do not learn from the cases they solve. This is especially concerning in medicine, where new clinical evidence, updated guidelines, and new therapies can change established practice. Fine-tuning can update the model, but it requires access to model weights and additional training. Parameter-free methods avoid training, but they may overfit a fixed validation set, lack reliable domain knowledge, or lose visual details by saving experience only as text. To address these limitations, we present a model-agnostic framework that allows frozen LLMs and VLMs to learn from deployment experience through three forms of external expertise: a Skill that guides reasoning and tool use, a Knowledge Memory that stores reliable facts supported by earlier cases or trusted external evidence, and a Multimodal Knowledge Base that keeps visual examples

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10:37 Arxiv.org CS World Models Dream of Success: Diagnosing and Repairing Failure Insensitivity in Robot World Models

arXiv:2610.09134v1 Announce Type: new Abstract: Robot world models support policy evaluation, planning, and synthetic data generation, but these applications require predictions that distinguish successful actions from failures. Across four released checkpoints from two architecture families, we observe weak sensitivity to action changes and success-like predictions on verified failures. Although recent work incorporates failures into model training, which data can repair released checkpoints without changing their architecture or training objective still remains underexplored. To this end, we introduce CureWM, which constructs alternative actions from successful demonstrations across a severity grid, verifies their outcomes through execution in simulation or on hardware, and fine-tunes released models on the resulting failures and surviving successes alongside nominal demonstrations. This construction provides controlled action contrasts from shared starting contexts. On 484 held-out

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10:22 Bioengineer.org AI Model Predicts Which Breast Cancer Patients Can Skip Unnecessary Surgery

Researchers at Heidelberg University Hospital developed a machine learning model combining ultrasound, mammography, MRI and clinical data to predict pathological complete response after neoadjuvant chemotherapy in breast cancer, achieving an AUROC of 0.76.

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10:22 Bioengineer.org Mapping the Hidden Battlefield: Spatial Atlas Tracks How Lung Tumors Evolve to Outsmart Targeted Drugs

A longitudinal spatial multi-omics study reveals how the tumor microenvironment in EGFR-mutant lung cancer remodels in distinct stages as patients develop resistance to sequential EGFR-targeted therapies.

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09:28 Arxiv.org Quantitative Finance OOM-RL II: Reality Is an Oracle, Not a Debugger Provenance-Constrained Diagnosis in Continually Evolving Agent-Engineered Systems

arXiv:2610.10256v1 Announce Type: cross Abstract: Reality may establish that an outcome occurred without identifying which evolving procedure produced it or why. This distinction matters in production ML systems whose code, configuration, and artifacts change while external feedback accumulates. We examine it in a human-directed, agent-engineered quantitative trading system, using oracle to mean an external source of realized outcomes rather than a complete correctness specification. Across one year, the account gained and outperformed a broad market index, while annual alpha was not statistically distinguishable from zero under the main retrospective specification. Retrospectively selected subperiods include adverse relative performance and conditional candidate-level weakness under declared approximate references. Engineering records document changes during the episode, and complete recommendation-to-runtime binding is unavailable. The archive does not establish a common frozen

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09:10 Odnako.org “Clone” investigation into stolen car trafficking: the Court of Crotone issues five convictions and five acquittals

The ordinary trial resulting from the “Clone” investigation by the Crotone Prosecutor’s Office into an alleged ring of cars that were allegedly stolen and then ... Read more L’article “Clone” investigation into stolen car trafficking: the Court of Crotone issues five convictions and five acquittals est apparu en premier sur Odnako.

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08:33 News-Medical.Net UK doctors transplant frozen testicular tissue to restore fertility

Doctors in Edinburgh have performed a pioneering procedure to transplant a young man's testicular tissue that was frozen before he underwent chemotherapy, in a potential breakthrough for male fertility preservation.

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08:20 Bioengineer.org America Is Running Out of Pancreas Transplant Surgeons

A new review warns that two decades of declining pancreas transplant volumes in the United States are eroding the training pipeline for the surgeons and physicians the field needs to survive.

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07:39 TechMeme.com Sources: Isomorphic Labs, an AI drug discovery startup spun out of Google DeepMind, is in early talks to raise funds at a valuation of at least $40B (Bloomberg)

Bloomberg: Sources: Isomorphic Labs, an AI drug discovery startup spun out of Google DeepMind, is in early talks to raise funds at a valuation of at least $40B  —  Isomorphic Labs, an AI-powered drug discovery startup spun out of Alphabet Inc.'s Google DeepMind, is in early talks to raise new funds …

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07:09 112.ua Teenager becomes first person to have testicular tissue transplant in UK

Operation on 19-year-old who had no sperm after chemotherapy offers hope of preserving children’s fertility after cancer treatment Surgeons have performed the first testicular tissue transplant on a teenager in the UK, offering hope that boys left infertile by chemotherapy could one day have biological children. The 19-year-old had his tissue removed and frozen three years ago before undergoing treatment for a serious blood disorder. He said he was “incredibly grateful” to the medical team behind the pioneering procedure, which represents a potential breakthrough for male fertility preservation. Continue reading...

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06:17 Bioengineer.org Gene Mutations After Liver Transplantation May Reveal Which Liver Cancer Patients Face Recurrence

Whole-exome sequencing of liver transplant patients with hepatocellular carcinoma has identified a 13-gene mutation signature that independently predicts tumor recurrence and survival.

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06:05 News-Medical.Net REUP technique expands access to pediatric heart transplants

A groundbreaking donor heart recovery technique developed at Vanderbilt Health has been successfully adapted for children by pediatric heart transplant surgeons at Monroe Carell Jr. Children's Hospital at Vanderbilt, potentially expanding access to lifesaving heart transplants for children.

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05:23 Bioengineer.org Gene Therapy With Goggles Lets Blind Patients See Objects, Five-Year Study Shows

A five-year clinical cohort study shows that an optogenetic therapy combining gene injection and light-stimulating goggles is safe and enabled several blind patients with advanced retinitis pigmentosa to detect and locate objects.

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04:56 Cnet.com Utah Now Allows AI to Scan Your Face and Prescribe Acne Medication

The program is limited in scope and can only prescribe medication for acne.

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03:33 Bioengineer.org Simulation and AI reshape how health care students rehearse hard decisions safely

A George Mason University scoping review of 83 studies finds that simulation, mobile platforms, and generative AI are transforming case-based learning in health care education, but only when technology serves clear learning goals supported by faculty guidance and reflection.

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02:25 MedicalXpress.com Protein LMOD1 offers new clues to muscle regeneration

Skeletal muscles are capable of regenerating themselves following an injury, a process that depends on muscle stem cells. In healthy resting muscle, these cells are predominantly in a quiescent state. However, following an injury, they are activated, begin to proliferate and subsequently start to develop into specialized skeletal muscle cells (differentiation). These cells then fuse with one another or with existing muscle fibers, generating new or repaired muscle fibers.

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00:19 112.ua Gene therapy can partly restore sight in blind people, researchers reveal

Optogenetic therapy, based on Nobel prize-winning science, involves turning nerve cells on and off using light A type of gene therapy based on Nobel prize-winning science is safe and can partly restore sight in blind people, researchers have revealed. The approach, known as optogenetic therapy, harnesses the technique for turning nerve cells on and off using light that scooped the 2026 Nobel prize in physiology or medicine. Continue reading...

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00:08 MedicalXpress.com Heart recovery technique adapted for pediatric transplants

A donor heart recovery technique developed at Vanderbilt Health has been successfully adapted for children by pediatric heart transplant surgeons at Monroe Carell Jr. Children's Hospital at Vanderbilt, potentially expanding access to lifesaving heart transplants for children.

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00:02 ScienceNews.org Gene therapy and special goggles give some blind people limited sight

Optogenetics, recognized by the 2026 medicine Nobel, makes cells respond to light, including eye cells that normally relay signals to the brain.

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07.10.2026
23:11 Bioengineer.org Transplant Drug Rewires Prostate Tissue in Two Distinct Phases, Rat Study Finds

A new rat study shows the immunosuppressant mycophenolate mofetil dismantles prostate stromal fibers in two timed phases, reshaping collagen, immune activity and androgen signaling.

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22:58 TechRepublic.com XtalPi Details Kodexia AI Platform for siRNA Drug Discovery

XtalPi’s Kodexia combines generative AI and automated lab testing for siRNA drug discovery. Explore its workflow, reported results and preclinical limits. The post XtalPi Details Kodexia AI Platform for siRNA Drug Discovery appeared first on TechRepublic.

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22:53 ScientificAmerican.Com Scientists unlock the longevity secrets of 194-year-old Jonathan the giant tortoise

The secret to Jonathan the tortoise’s extreme longevity may be in keeping genes tidy

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22:44 MedicalDaily.com Cigarette Smoke Reprogrammed Lung Stem Cells in Lab Models and Helped Steer Which Lung Cancer Type Formed

A Johns Hopkins lab study found that cigarette smoke primed lung stem cells for specific cancer types. What it shows and what it does not prove.

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22:27 MedicalXpress.com Phthalate byproduct affects multiple cell types in human ovarian tissue, lab tests show

Common chemicals called phthalates, which are used in plastics, cosmetics and personal care products, may affect several different cell types in the human ovary. This is shown in a new study from Karolinska Institutet published in the journal eBioMedicine.

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21:46 Phys.org Compact CRISPR alternative uses bacterial proteins to insert large DNA segments

A new engineered gene-editing system, proven in bacteria and showing promise for use in plants, animals and humans, addresses some limitations of current gene-editing tools, with the goal of improving their use in research, crop development and disease treatment.

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21:27 112.ua Jonathan the giant tortoise, 194, offers up insight into secrets of longevity

DNA analysis of oldest living land animal reveal patterns on genes that appear to protect functioning of mitochondria The ancient quest to extend human lifespan has received a boost after scientists analysed the genetic code of the world’s oldest living land animal, a giant tortoise called Jonathan. The tortoise, which lives in the grounds of Plantation House, the official residence of the governor of Saint Helena in the South Atlantic, is believed to be 194 years old, making him a contemporary of Queen Victoria and Charles Darwin. Continue reading...

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20:00 Phys.org A new hope for dogs with dementia: Researchers explore gene therapy

The moment Kate Heath saw her 12-year-old pug, Ivy, sitting silently and staring at a wall, she knew something was wrong.

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19:59 News-Medical.Net Researchers identify new protein regulator of muscle stem cell differentiation

Researchers at the Leibniz Institute on Aging—Fritz Lipmann Institute (FLI) in Jena and the BTU Cottbus-Senftenberg in Senftenberg have identified a previously unknown regulator of muscle stem cell differentiation.

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19:28 MedicalXpress.com Clinical trial tests AI-assisted medication device for older adults with memory loss

Marianne Blake has lived in the same home for nearly half a century. She plays bridge regularly, drives to her hair appointments and, at 88 years old, enjoys her independence.

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19:11 Bioengineer.org AI, Geometry, or Blood Flow? Study Pits Three Models Against Each Other in Liver Surgery Planning

A comparative study of 104 liver cancer patients shows that geometric, perfusion-based, and deep learning models each excel at different surgical scenarios, offering surgeons modular tools for tissue-sparing resection planning.

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18:39 Bioengineer.org Data-Efficient AI Transformer Hits Near-Perfect Accuracy in Lung Cancer Diagnosis

Researchers report that a data-efficient vision transformer classified lung cancer histopathology images with 98.64 percent accuracy and near-perfect AUC while outpacing rival models in inference speed.

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18:29 Nature.com (news) Alveolar stem cells transdifferentiate to drive bronchiolar regeneration

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18:20 Nature.Com Cryo-EM structure of a methanogen nitrogenase–PII protein supercomplex

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18:20 Nature.Com Alveolar stem cells transdifferentiate to drive bronchiolar regeneration

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17:39 Bioengineer.org Brain-Computer Interface Feedback Teaches the Brain to Spot Tiny Movement Errors

A five-day brain-computer interface training protocol that feeds back the brain's own error-related potentials significantly improves people's ability to detect tiny visuo-motor errors that conventional practice cannot, according to a new study in Advanced Science.

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17:06 Bioengineer.org Engineered Flavonoid Cousins of Fisetin Clear Senescent Cells and Boost Healthspan in Mice

Researchers engineered two fisetin-derived flavonoid analogs that kill senescent cells up to 27 times more potently than fisetin and reduce senescence markers in aged mice by targeting PARP1 and CDK2.

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17:06 Bioengineer.org Weak Pump Function Predicts Poor Outcomes After Stenting in Heart Transplant Patients

A German study of 159 heart transplant recipients found that a reduced left ventricular ejection fraction independently predicts lower stenting success and nearly tripled three-year mortality after percutaneous coronary intervention.

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16:56 TheNextWeb.com Rivercell raises $25M to build an AI model of how cells respond to drugs

Paris start-up Rivercell has raised a $25M seed round to build an AI model that predicts how human cells respond to drugs and genetic changes. HV led the round, with HCVC, Alven and Bpifrance Digital Venture taking part, the company said on Wednesday. The money will pay for Rivercell’s data platform, a bigger wet lab […] This story continues at The Next Web

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16:34 Bioengineer.org Mini-GRID Radiotherapy Curbs Cellular Senescence While Keeping Its Anti-Tumor Punch in Glioma Cells

A preclinical study finds that spatially fractionated mini-GRID radiotherapy preserves the growth-inhibitory effect of radiation in glioma cells while markedly reducing senescence, persistent DNA-damage markers and SASP induction compared with conventional radiotherapy.

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16:17 Bioengineer.org New AI Tool miRDrug Maps the Shared Genes Behind MicroRNAs, Drugs and Resistance

Researchers have developed miRDrug, a machine-learning platform that integrates three biological databases to map the shared genes linking microRNAs, drugs and resistance mechanisms, with striking results in breast cancer subtyping.

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15:59 Bioengineer.org Stem Cell Vesicles Quiet Inflammatory Immune Signals in Osteoarthritis Patients

A new in vitro study reports that mesenchymal stem cell-derived extracellular vesicles reduced Th1 cell frequency, STAT1 expression, and inflammatory cytokine production in immune cells from osteoarthritis patients.

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13:17 Arxiv.org Physics Erasing and Regenerating the Turbulent Cascade Arrow

arXiv:2610.07449v1 Announce Type: new Abstract: Which information tells a turbulent flow which way to cascade? We apply Haar-distributed Hermitian phases that retain prescribed same-mode quadratic information, including modal amplitudes, the energy spectrum, and same-mode two-time correlations. For the phase-Haar ensemble, the expectation of any integrable odd flux functional is zero. Finite ensembles strongly suppress mean transfer and forward-event bias in the primary block. An independent block retains sign separation but fails the scale-8 mean criterion. In matched evolution protocols, nonlinear Navier-Stokes dynamics restores the selected signed-flux scalar close to its natural reference, whereas linear evolution and an amplitude-matched frozen control do not. Flux and a local cubic geometry scalar recover together, yet high local correlation can survive erasure of the arrow. Signed transfer thus requires information beyond the retained quadratic record; the tested nonlinear

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13:17 Arxiv.org CS Entropy-Guided Reverse-Causal AI to Identify Upstream Bottleneck Genes for Alzheimer's Drug Discovery

arXiv:2610.08736v1 Announce Type: new Abstract: Identifying upstream regulators that connect several disease processes to therapeutic interventions is a central objective in Alzheimer's disease drug discovery. We propose an entropy-guided reverse-causal framework that makes candidate bottleneck genes the organizing link between disease mechanisms, pathways, molecular targets and drugs. The methodology integrates five stages: an Alzheimer's-specific knowledge graph with language-model assistance and expert review; reverse tracing from drugs to candidate genes; entropy-guided prioritization; forward propagation to drugs and complementary combinations; and staged validation with evidence feedback. The novelty lies in integrating upstream bottleneck identification, entropy-guided prioritization and iterative therapeutic selection within a dynamic, bidirectional discovery architecture. We demonstrate its molecular tracing and gene-prioritization components in a computational feasibility

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13:17 Arxiv.org CS Enhancing Energy Harvesting in Harmonically Forced Oscillators via Regenerative Impulsive Braking

arXiv:2610.08488v1 Announce Type: new Abstract: This paper investigates whether regenerative impulsive braking can enhance passive energy harvesting in harmonically forced oscillators. An impulsive braking event directly extracts kinetic energy while simultaneously inducing a transient that alters subsequent passive harvesting. The analysis shows that suitably timed braking can produce a net energy gain over passive harvesting alone. The braking-induced transient is derived analytically and used to obtain an exact expression for the harvested-energy gain over an arbitrary finite post-braking horizon, together with conditions for positive gain and the optimal braking instant. The corresponding infinite-horizon analysis shows that optimal braking occurs at zero crossings of the harmonic excitation, with complete braking maximizing the gain. Numerical results further show that the finite-horizon harvested-energy gain can exceed its infinite-horizon value. Simulations using short-duration

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13:17 Arxiv.org CS Multi-Dataset Diagnostic Utility of Clinical Visual Concepts in AI Systems for Dermatology

arXiv:2610.08086v1 Announce Type: new Abstract: The clinical integration of AI systems in digital dermatology relies heavily on human trust. Clinically interpretable visual concepts can act as intermediate representations enhancing trust and reliability. However, research in this domain is currently limited by scattered, heterogeneous dataset annotations. In this work, we introduce SkinLex, a harmonized dataset of 48 clinical morphological attributes across four public datasets (SkinCon, DermaCon-IN, MM-Skin, and PASSION) for a total of 20,411 records. Supervised nine-partition classification of skin conditions shows that limiting features to specific visual groups, like shapes or colors alone, reduces diagnostic accuracy. Bootstrapped backward elimination reveals that the set of 48 visual concepts has some degree of redundancy for algorithmic nine-partition diagnosis on the examined dataset. This demonstrates that coarse diagnosis on the selected dataset requires a relatively small

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13:17 Arxiv.org CS Benchmarking Label-Revealed Online Updates for EEG BCI Decoding

arXiv:2610.07420v1 Announce Type: new Abstract: Electroencephalography (EEG) signals drift over time, which can cause static brain-computer interface (BCI) models to degrade in practice. We present a benchmark for online adaptation and compare two widely used pipeline families, Common Spatial Patterns (CSP) and Riemannian covariance-based methods, under time-ordered prequential (test-then-train) evaluation. We examine (i) which pipelines benefit most from label-revealed updates, (ii) whether controlled forgetting of older data improves robustness, and (iii) how a minimal-calibration cold start compares with starting from a pretrained model. Across four datasets (three motor-imagery datasets and one movement-decoding dataset), label-revealed online updates improve 13 of 14 model/dataset pairs on the two largest streams, with relative accuracy gains of up to about 18% over a frozen model. A Shapley-based data-valuation analysis over temporal blocks assigns the largest mean value to the

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13:17 Arxiv.org CS Behavioral Cloning Mystery

arXiv:2610.07056v1 Announce Type: new Abstract: Behavioral cloning (BC), despite its simplicity, exhibits many counterintuitive phenomena in the real world. For example, the performance of BC often keeps increasing as the model overfits more to the dataset, and fully closed-loop policies often completely fail without action chunking. Unfortunately, properly studying these anecdotal phenomena ("behavioral cloning mysteries") is challenging: in the real world, datasets and experiments are costly and not fully controllable; in simulation with synthetic data, these phenomena are often not easily observed partly due to the discrepancy between scripted policies and human demonstrations. In this work, we propose OCBench, a robotic manipulation benchmark with controllable scripted policies that have similar properties to human demonstrations. We show that, by mimicking key properties of human demonstrations, OCBench reproduces many anecdotal BC-related phenomena in controlled settings. With

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13:16 Bioengineer.org Breakfast Habits and the Mediterranean Diet: New Study Maps Hidden Teen Nutrition Groups

A new Pediatric Research study uses latent class analysis to reveal hidden subgroups of adolescent dietary behavior, linking breakfast habits and Mediterranean diet adherence to well-being.

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12:56 112.ua Moment Karl Deisseroth tells his family he won the Nobel prize in medicine – video

Stanford University has shared video of Karl Deisseroth giving the news to his two daughters and one of his sons on Monday. Deisseroth had spent hours fielding congratulatory calls after learning that he had won a Nobel prize in medicine for helping to open a new field of brain science called optogenetics. But it wasn't long before the California scientist asked for a break from all the attention for a more ordinary task: he needed to make school lunches for his children, who were asleep in the family home in Stanford, where their father had been speaking in the middle of the night with journalists and wellwishers. Deisseroth, 54, shared this year’s medicine prize with two researchers in Germany for their work in optogenetics, a field that combines light with genes to switch neurons on and off in living brains Nobel prize in medicine 2026 awarded for research into mysteries of brain Continue reading...

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11:58 MedicalDaily.com From Cancun to Miami: John Merola and RejuvStem's Move Into Florida's New Stem Cell Market

As that interest has grown, and as states like Florida have expanded access to stem cell therapies, a number of companies that have long served American patients abroad are now building capacity closer to home. RejuvStem is one of them.

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11:35 112.ua Nobel prize in medicine 2026: unlocking the mysteries of the brain

Kicking off the 2026 Nobel prizes in is the award for physiology or medicine. This year the prize went to three scientists for their work investigating the mysteries of the brain. Karl Deisseroth of the Howard Hughes Medical Institute and Stanford University, Peter Hegemann of the Humboldt University of Berlin and Georg Nagel of the University of Würzburg have been awarded the prize “for their discoveries concerning light-gated ion channels and optogenetics”. Science correspondent Nicola Davis tells Madeleine Finlay how this technique is already transforming neuroscience and how it could one day help restore sight, remove pain and tackle diseases like addiction and Alzheimer's Continue reading...

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10:04 Phys.org Sleep, appetite, gene-editing experts contend for Nobel chemistry prize

Research into molecules that regulate sleep and appetite or methods for editing genes could be among the contenders for the Nobel Prize in chemistry, to be announced Wednesday, commentators say.

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06:57 Bioengineer.org Medical Interpreters Do Far More Than Translate—and AI Cannot Replace It Yet

A qualitative study of 17 medical interpreters finds they perform eleven resilience-enhancing safety behaviors that current AI interpretation tools cannot replicate.

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06:43 Bioengineer.org AI Reads MRI Scans to Predict Hidden Gastric Cancer Spread Before Surgery

Researchers in Guangzhou built a machine-learning model that combines MRI radiomics and clinical variables to predict lymphovascular invasion in gastric cancer before surgery and to stratify patients by disease-free survival risk.

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06:32 MedicalDaily.com AI Companies, Not Utah, Pay the Evaluators Checking Their Health Tools in the State's Expanding Sandbox

Utah's health AI sandbox lets companies pay the third-party evaluators checking their tools, raising independence questions as new pilots begin.

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06:30 Google news Health SEC football player needs heart transplant, emotional coach asks for prayers - AL.com

SEC football player needs heart transplant, emotional coach asks for prayers  AL.comMissouri OL Jones in need of heart transplant, Drinkwitz says  ESPNFreshman Mizzou football player in need of heart transplant, coach Eli Drinkwitz says  KMBCMissouri coach Eli Drinkwitz says freshman offensive tackle Johnnie Jones is in need of a heart transplant  Yahoo SportsMissouri OL Johnnie Jones Hospitalized, Needs Heart Transplant After Undergoing Medical Testing  Bleacher Report

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06:30 Google news Sci/Tech SEC football player needs heart transplant, emotional coach asks for prayers - AL.com

SEC football player needs heart transplant, emotional coach asks for prayers  AL.comMissouri OL Jones in need of heart transplant, Drinkwitz says  ESPNFreshman Mizzou football player in need of heart transplant, coach Eli Drinkwitz says  KMBCMissouri coach Eli Drinkwitz says freshman offensive tackle Johnnie Jones is in need of a heart transplant  Yahoo SportsMissouri OL Johnnie Jones Hospitalized, Needs Heart Transplant After Undergoing Medical Testing  Bleacher Report

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02:20 FoxNews.com People who live to 100 have 3 drinks in common, longevity expert says

Dan Buettner highlights how blue zones residents drink water, black coffee and red wine with resveratrol to support long-term health goals.

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01:50 Google news Health Missouri coach Eli Drinkwitz says freshman offensive tackle Johnnie Jones is in need of a heart transplant - Yahoo Sports

Missouri coach Eli Drinkwitz says freshman offensive tackle Johnnie Jones is in need of a heart transplant  Yahoo SportsMissouri OL Jones in need of heart transplant, Drinkwitz says  ESPNMizzou freshman O-lineman needs heart transplant; no change to Ahmad Hardy's status  STLtoday.comMissouri freshman offensive lineman hospitalized, needs heart transplant  The New York TimesMissouri freshman DJ Jones placed on heart transplant list, Eli Drinkwitz says  CBS Sports

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01:50 Google news Sci/Tech Missouri coach Eli Drinkwitz says freshman offensive tackle Johnnie Jones is in need of a heart transplant - Yahoo Sports

Missouri coach Eli Drinkwitz says freshman offensive tackle Johnnie Jones is in need of a heart transplant  Yahoo SportsMissouri OL Jones in need of heart transplant, Drinkwitz says  ESPNMizzou freshman O-lineman needs heart transplant; no change to Ahmad Hardy's status  STLtoday.comMissouri freshman offensive lineman hospitalized, needs heart transplant  The New York TimesMissouri freshman DJ Jones placed on heart transplant list, Eli Drinkwitz says  CBS Sports

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01:01 DiscoverMagazine.com 100-Year-Old Women in a Tiny Sardinian Village Could Make it the World’s Next Blue Zone

Discover how historical records reveal an unusually high number of centenarians in Bolotana, where women are especially likely to live past 100.

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00:04 InsideEVs.com Mitsubishi's Clone Of The Nissan Leaf Isn't All That Cheap

The base Eclipse Sportback EV is $8,000 more expensive than the entry-level 2027 Leaf.

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00:02 Phys.org Hydra loses its immortality after cold triggers switch to sexual reproduction

The freshwater polyp Hydra oligactis is essentially immortal and reproduces asexually by cloning itself. Except when it gets too cold: then the animal switches to sexual reproduction, begins to age, and eventually dies. A research team at the University of Innsbruck has now investigated the metabolic changes that accompany this process. One of the findings: the aging process is accompanied by a sharp decline in taurine.

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