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A new safety audit shows that machine unlearning in medical AI can silently degrade performance on rare diagnoses, and proposes a framework to detect and mitigate this spillover.

Surgeons have shown that robotic technology can help repair a rare and difficult type of hernia that develops along the side of the abdomen. These hernias are hard to treat because they form near the ribs, pelvis, muscles, nerves and blood vessels.

VIB researchers have developed a new human stem-cell-based model that recreates an early stage of immune-cell development and shows how a single progenitor population can give rise to specialized macrophages across different organs. The model provides a platform to study how these processes change in disease, and how they might eventually be harnessed therapeutically.

Google is investing in Flo Health to connect menstrual cycle tracking with wearable data, expand women's health research, and develop personalized AI tools. The post Google Invests in Flo Health to Bring Period Tracking to Wearables appeared first on TechRepublic.

Researchers identified eleven WOX genes in the medicinal tree Eucommia ulmoides and showed that overexpressing EuWOX11 in poplar dramatically increases adventitious root formation, root length, biomass and vegetative growth.

Some people are born with a defect in their genetic material that prevents their immune system from functioning properly. In people with a condition known as GATA2 deficiency, the body does not produce enough immune cells, leaving them at increased risk of infections and disease. Now, researchers at Aarhus University have demonstrated that they can repair the genetic defect directly in patients' own blood stem cells.

Researchers have developed a three-stage protocol that reliably converts adipose-derived mesenchymal stem cells into functional lymphatic endothelial precursor cells, which engraft into host lymphatic vessels in a mouse wound-healing model.

A deep learning model trained exclusively on adult duodenal biopsy images has achieved pathologist-level accuracy in diagnosing coeliac disease in children across independent hospitals and scanner platforms, with no misclassifications among high-confidence predictions.

Chinese researchers have built an interpretable FTIR spectroscopy and machine learning framework that reliably distinguishes raw, nine-steamed-and-nine-sun-dried, honey-processed, and wine-processed Polygonatum sibiricum products.

Researchers used graphene oxide to restructure stem cell spheroids into multiple smaller aggregates, nearly doubling exosome yield and producing vesicles that accelerated vascularized wound healing in rats.

A map built from more than 14,000 embryo cells reveals what stem cell models get right about early human development and where researchers could improve them. Under a microscope, a cluster grown from stem cells can resemble a human embryo in its first days of development. These structures, called blastoids, offer scientists a way to [...]

In the field of radiology, AI models have the potential to improve imaging analysis, speed up diagnoses and catch errors that might otherwise be missed. But the vast majority of these models are trained on adult data and don't translate well to infants and children, keeping these advances out of reach of neonatal and pediatric care.

A new knowledge distillation framework compresses three large neural networks into a 6.97 MB model that classifies rice diseases, localizes infections, and quantifies severity on a budget smartphone in under 15 milliseconds.

NASHVILLE, Tenn. — Liver transplantation yielded favorable short- and intermediate-term outcomes for patients with unresectable colorectal liver metastases confined to the liver, according to a study presented at ACG Annual Meeting.Additionally, incidence of graft-related mortality after transplant was low, with most deaths among transplant recipients related to malignancy.“Liver transplantation for unresectable colorectal liver metastases is an emerging indication, but its role in the United States remains highly selective and continues to evolve,” Ragesh B. Thandassery, MD, a hepatologist

A new European report says AI can improve care, but only if doctors stay in charge and high-risk systems remain under strict human oversight.

The investment will expand continuous cover forestry across Europe, and represents SLM Silva Fund II's first and final close. The post SLM Partners secures $167m from Dutch pension investor to regenerate forests appeared first on AgFunderNews.

A new review charts how stem cell-derived human microglia, brain organoids and chimeric mice are overcoming the genetic and environmental limits of traditional models to transform the study of neuroimmune disease.

Researchers have built AMIFound, a single foundation model trained on 3.76 million image pairs that restores and enhances medical images across seven modalities, outperforming 38 specialist baselines and improving downstream disease detection and cancer prognosis.

UC Davis Health research has found that people who received a kidney from a living donor with a history of smoking face a higher risk of transplant failure. Transplant failure, known as graft loss, occurs when the transplanted kidney permanently stops working. The highest risk was among patients whose donors had a substantial smoking history.

It is always good to see a diversification in non-profit efforts to advance the state of research and development in the matter of treating aging as a medical condition. Given the vast costs imposed by aging, humanitarian and fiscal, we stand a long way removed from the deployment of an adequate amount of funding for aging research. New advocates and new organizations are very welcome, to add to existing efforts to induce more funding for necessary research, and more capital into the longevity industry. We started Second Century Foundation to fulfill our childhood dream of a world where no one has to suffer or die from aging. Second Century Foundation is a 501(c)(3) private operating foundation focused on accelerating breakthroughs in human longevity. Much of […]

Cells become senescent in response to various forms of damage and stress, including the stress induced by reaching the Hayflick limit on replication. This was first described in the context of replicative senescence in cell cultures, and from there cellular senescence became a topic of interest in cancer research. In more recent years, the accumulation of senescent cells in aged tissues was demonstrated to be an important contribution to degenerative aging, and a small industry of biotech companies has emerged to develop a variety of therapies to either selectively destroy or modulate the behavior of senescent cells. The history of cellular senescence is, in many ways, a history of expanding biological complexity. What began as an observation of finite proliferative capacity in cultured cells has […]

An NYU Abu Dhabi study in EMBO Reports shows that a single cancer-causing gene drives liver cells into distinct senescent states, some permanently tumor-suppressive and others reversible, with major implications for senolytic cancer therapy.

A kidney transplant patient developed HLH, a rare immune overreaction, from a cat-scratch bacterium. Gene sequencing finally exposed the culprit.

An optogenetic gene therapy used with special goggles improved light sensitivity in 7 of 10 people with advanced retinitis pigmentosa in a small trial.

Researchers have built an LLM-based conversational virtual patient with an automated evaluation engine that lets medical students practice clinical interviews and receive instant feedback, earning strong usability scores in an initial validation study.

Patients are using AI to analyse hospital bills and dispute possible errors, but experts warn the technology may increase costs, misclassify charges and expose consumers to privacy and financial risks.

A meta-analysis of 40 studies covering 12,769 patients shows that radiomics-based models combining CT image features with clinical data can predict high-risk pathological features in gastric cancer with pooled AUCs of up to 0.90, though multicenter external validation is still needed.

Researchers have developed Adaptive-CGAN, a generative AI framework that produces realistic synthetic chest X-rays, lifts diagnostic accuracy to 99.60 percent, and cuts training carbon emissions through optimized cloud deployment.

In a phase 1 study of 10 adults with advanced retinitis pigmentosa, researchers found that optogenetic gene therapy combined with light-stimulating goggles was generally well tolerated, although one participant experienced a severe but transient ocular adverse event. Seven participants showed improved light sensitivity, while four of eight who completed behavioral testing demonstrated modest gains in visual function, providing preliminary evidence of partial vision restoration that requires confirmation in larger controlled trials.

The first Europe-wide expert working group on Artificial Intelligence in mental health launches today to the ECNP congress in Munich, where the group will host an open discussion, setting out the potential, the problems, and possible directions for AI in psychiatry and neuroscience.

The first Europe-wide expert working group on artificial intelligence in mental health has launched at the ECNP Congress in Munich with a three-year plan to map, evaluate and guide the regulation of AI across European psychiatry.

Johns Hopkins University engineers have created robots the size of a pencil tip intended to travel through the body to deliver medicine to infections inside a beating heart.

Northwestern Medicine scientists have identified a stem-like state in small-cell lung cancer that distinguishes a group of patients with exceptionally poor outcomes following chemoimmunotherapy, according to a study published in Cell Reports Medicine.

Apple TV today announced “Heart,” an original eight-episode true-crime podcast involving two men linked by a donated heart and the same terrible demise. Here are the details. more…

Women who stay on aromatase inhibitors for 5 years have higher risks of hypertension, dyslipidemia, and diabetes vs their non-adherent counterparts. Yet their mortality rate is lower.

A Harvard-led study of more than 1,300 pregnancies found that a Mediterranean-style prenatal diet and regular seafood consumption were associated with significantly lower infant risk of colic and eczema.

Cancer incidence after solid organ transplant varies significantly based on transplant and malignancy type.A study of more than 620,000 patients who received heart, kidney, liver or lung transplant showed that patients who had lung transplants had the greatest incidence rates for solid tumors, nonmelanoma skin cancer and posttransplant lymphoproliferative disorder (PTLD).Additionally, bladder, colorectal, genital and lung cancer incidence increased over time, whereas melanoma, thyroid cancer and PTLD rates dropped after high early incidence.“This is something we should be more observant of,

If you are planning to buy a Shelby Mustang, there are a few key things to look out for to ensure you are not getting a clone or fake car for a premium price.

Cells become senescent in response to stress and damage, in response to tissue injury, but most commonly upon reaching the Hayflick limit to replication. A senescent cell ceases to replicate, grows in size, and generates a potent mix of pro-growth, pro-inflammatory signals. Senescent cells are created throughout life in tissues throughout the body, but an established population of lingering senescent cells only begins to accumulate in later life. In youth, the immune system efficiently clears senescent cells, allowing senescence to be a beneficial state in the coordination of regeneration and in drawing the attention of the immune system to potentially cancerous cells. In later life, the immune system falters in this task. An established population of senescent cells that generates signaling constantly, even in relatively […]

Donor organs are exceedingly scarce, so much so that one in five people on the waiting list for a heart transplant in the U.S. dies or is removed from the list before receiving a transplant.

Researchers report the first CRISPR/Cas12a editing of sugarcane, showing that co-expressing the mTREX2 exonuclease boosts large deletions seven-fold and enables efficient multiallelic editing of the lw1 gene in the crop's highly polyploid genome.

A fusion of CT-based habitat radiomics and 3D deep learning predicted the hidden STAS invasion pattern in early-stage lung adenocarcinoma with an AUC of 0.824 before surgery.

A new review in Current Research in Food Science details how artificial intelligence, CRISPR gene editing and RNA interference are converging to cut the 25 to 50 percent of fruits and vegetables lost after harvest each year.

Donor organs are exceedingly scarce, so much so that one in five people on the waiting list for a heart transplant in the U.S. dies or is removed from the list before receiving a transplant.

InvestorPlace - Stock Market News, Stock Advice & Trading Tips Neuralink is private, but Butterfly Network and Quantum-Si offer two very different public-market angles on brain-computer interfaces. The post 2 Brain-Computer Interface Stocks to Watch While Neuralink Stays Private appeared first on InvestorPlace.

Google has taken a stake in Flo Health, the period-tracking app, the companies said on Monday. The multi-year deal will bring women’s health data into Google’s wearables and coaching. They did not disclose the size of the investment. From early 2027, users will be able to sync Flo with the Google Health app, Engadget reported. Fitbit readings such as […] This story continues at The Next Web

Google's Sleek New Fitbit Edge Is Packed With Health Features And A Replaceable Battery  EngadgetGoogle Fitbit Edge: Our all-new smartest fitness tracker ever  blog.googleGoogle Debuts $180 Fitbit Edge Tracker in Continued Health Push  Bloomberg.comGoogle announces the Fitbit Edge, a middle ground between Pixel Watch 5 and Fitbit Air  Ars TechnicaThe Fitbit Edge is for folks who don’t want to go totally screenless  The Verge

Google's Sleek New Fitbit Edge Is Packed With Health Features And A Replaceable Battery  EngadgetGoogle Fitbit Edge: Our all-new smartest fitness tracker ever  blog.googleGoogle Debuts $180 Fitbit Edge Tracker in Continued Health Push  Bloomberg.comGoogle announces the Fitbit Edge, a middle ground between Pixel Watch 5 and Fitbit Air  Ars TechnicaThe Fitbit Edge is for folks who don’t want to go totally screenless  The Verge

A Chinese clinical study reports that donor-derived anti-CD19 CAR-T cells achieved complete remissions in 13 of 14 patients whose B-cell acute lymphoblastic leukemia relapsed after stem-cell transplantation, including most patients with extramedullary disease.

New research reveals that the Hippo pathway effector YAP1 acts as a master switch controlling whether adult spinal cord stem cells become myelin-producing oligodendrocytes or scar-forming astrocytes.

Cheyenne MacDonald / Engadget: Google says Health Guardian is launching later in October on the Fitbit Air and Edge for Google Health Premium users, and expands automatic activity tracking  —  The company also announced a new metal mesh band for the Fitbit Air.  —  Google is rolling out a pair of updates …

Researchers discovered that the RNA-modifying enzyme PUS7 pseudouridylates the noncoding RNA 7SK to recruit the BAF chromatin-remodeling complex, enabling a new OCT4-free recipe for making high-fidelity human iPS cells.

Johns Hopkins engineers have developed wireless, magnetically steered millirobots that travel through the bloodstream to dock on a beating heart and deliver antibiotics directly to infected tissue, potentially replacing weeks of IV therapy or open-heart surgery.

arXiv:2608.28620v2 Announce Type: replace Abstract: Preference elicitation is essential for aligning AI systems with human values. Prior approaches (e.g., for organ allocation) often ask stakeholders to compare the decisions of an algorithm (e.g., patient A vs. patient B). Such a decision-level approach conflates the means with the ends. Instead, we elicit preferences directly over allocation outcomes to learn a utility function for policy optimization. We construct a novel preference elicitation algorithm for linear utilities that outperforms prior techniques in practice. Our algorithm has two phases. The first phase learns cutting planes through pairwise comparisons to rapidly shrink the space of possible attribute weights and warm-starts the second phase by eliminating dominated regions. The second phase then provably converges to the user's utility function. We apply our technique to heart transplant allocation, where a policy must balance competing objectives such as

arXiv:2610.13894v1 Announce Type: new Abstract: Nimbus Studio is a visual pipeline platform for brain-computer interface (BCI) experiments: researchers assemble preprocessing, feature extraction, decoding, and evaluation over public benchmark datasets or their own recordings, with cross-validated evaluation protocols (including leave-one-subject-out), BIDS export, and bring-your-own Python model classes. Whether its numbers can be trusted is a fair question for any such platform. We answer it with a parity study: six standard BCI decoding pipelines (CSP+LDA, Riemannian MDM, tangent-space logistic regression through the platform's bring-your-own-code node, P300 xDAWN+LDA, and the deep ShallowConvNet and EEGNet) were evaluated on three public datasets (motor-imagery BNCI-2014-001/004; P300 BNCI-2014-009) under two protocols (per-subject session holdout and pooled leave-one-subject-out cross-validation via the platform's planned-CV driver), once through Nimbus Studio's execution engine

arXiv:2610.13054v1 Announce Type: new Abstract: Recently, generative neural synthesizers have enabled zero-shot instrument cloning from reference recordings and timbre generation from text prompts. However, existing systems generate complete audio segments offline, precluding their use as playable instruments. We present LiveSynth, a streaming neural synthesizer with flexible timbre control and interactive generation capabilities, including zero-shot instrument cloning and text-to-instrument synthesis. A feedback-free causal Transformer conditioned on MIDI events and a CLAP timbre embedding outputs continuous audio latents at 100 Hz, which a causal variational autoencoder decodes into audio. Frame-wise timbre conditioning enables continuous timbre morphing, while MIDI-conditioning dropout enables autonomous continuation from a performed prefix. On the NSynth and Slakh datasets, LiveSynth achieved timbre similarity and spectral reconstruction quality comparable to offline baselines. On

A Chinese research team has shown that machine learning analysis of tumor sub-regions and surrounding tissue on non-contrast CT scans can accurately distinguish benign from malignant sacral tumors before surgery.

Researchers developed a 20-item scale for judging biological meaning in health-related images and showed that multimodal AI models can apply it with high consistency, though day-to-day stability and one subscale need work.

A four-week smartphone-based education program for mothers significantly and sustainably improved parent-reported quality of life in pediatric heart transplant recipients, outperforming face-to-face teach-back instruction, according to a new quasi-experimental study published in BMC Pediatrics.

A field study in China's Loess Hilly Region finds that mixed pine and black locust plantations are more stable than pure stands, but weak natural regeneration threatens their long-term persistence.

Peter Hegemann, Georg Nagel and Karl Deisseroth turned a light-sensitive protein from algae into a tool for switching brain cells on and off, giving the study of emotion, memory and behavior a causal, material basis. The prize comes as the Trump administration guts the research and health care this science should serve.

In a Lancet study, Google's AMIE AI interviewed 98 patients before urgent visits with no safety stops. What doctors measured and what it cannot prove.

A new review charts how stem cell transplantation, lentiviral gene therapy, and CRISPR-based editing such as Casgevy are turning beta-thalassemia from a lifelong transfusion-dependent illness into a potentially curable disease, while cost and access hurdles remain steep.

Sea cucumber tissue kept growing for more than three years after removal, surviving in seawater teeming with microbes. Like Thing, the disembodied hand in The Addams Family, a severed piece of sea cucumber tissue kept living without the body it came from, prompting scientists to describe the animal as a “real-life zombie.” Weeks after being [...]

A quantitative analysis of 42 medical AI policies from seven major economies finds strong strategic vision but weak implementation tools, with only two policies earning a top-grade rating.

A multimodal deep learning model combining MRI scans with clinical data classifies Alzheimer's disease stages with up to 95 percent accuracy, offering a promising path toward earlier diagnosis.

Researchers have linked 3D-printed collagen scaffolds, scaled-up stem cell expansion, and perfusion bioreactor cultivation to grow large, mineralized bone constructs without exogenous growth factors.

A multi-omics study has mapped stage-specific lipid remodeling across human stem cell differentiation into cardiomyocytes, revealing that polyunsaturated phospholipids accumulate as cells mature and that phosphatidylcholine supplementation modulates maturation and hypertrophy gene programs.

A gut bacteria-derived bile acid called hyodeoxycholic acid restores aging bone marrow stem cells and reverses bone loss in a mouse model of postmenopausal osteoporosis by activating a TGR5-ESR1 mitophagy pathway.

New cell research shows prolonged tadalafil exposure boosts proliferation of muscle progenitor cells, suppresses myostatin and TGF-beta, and delays terminal differentiation, suggesting therapeutic promise for muscle-wasting disorders while raising anti-doping concerns.

A single-cell multi-omic atlas of neuroendocrine carcinoma of the cervix identifies DLL3 as a driver of immune evasion and validates DLL3-targeted therapy in patient-derived organoid models.

Clinicians in Chongqing report an extremely rare case in which Bartonella henselae bacteremia from a kitten scratch triggered hemophagocytic lymphohistiocytosis in a kidney transplant recipient, diagnosed by metagenomic sequencing and successfully treated with short-course antibiotics and immunomodulatory therapy.

A new metabolomic study shows that mouse retinal organoids share 148 of 166 detected metabolites with native retina, yet reveal selective immaturity in glycolytic, TCA cycle, and amino acid metabolism that points the way to better culture conditions.

Researchers have built a multilingual transformer-based AI system that diagnoses crop diseases, generates farming advice, and delivers market intelligence while sustaining 10,000 concurrent users at 0.35 seconds per query.

Researchers in Shandong, China, have developed and externally validated machine learning models that use preoperative data to predict complications, prolonged hospital stay, and postoperative pain in patients undergoing surgery for thymic epithelial tumors.

A multicenter study found that a deep learning model analyzing full ultrasound videos significantly improved diagnostic accuracy for suspicious breast lesions, lifting junior sonographers' accuracy from 66.7% to 89.2%.

A prospective Polish study shows that patients who develop graft-versus-host disease in the first six months after allogeneic stem cell transplantation suffer persistently worse fatigue and quality of life, with fatigue emerging as a strong, potentially modifiable driver of patient well-being.

Critical Path Institute and the University of Arizona have launched a two-year collaboration using human stem cell-derived neurons and new approach methodologies to uncover the sex-specific cellular biology of Parkinson's disease in women.

Scientists have demonstrated a promising new approach to restoring limited vision in people with advanced inherited blindness. An experimental treatment combining gene therapy with specialized goggles has helped some people with advanced blindness detect objects and respond to visual cues. Instead of attempting to repair damaged light-sensing cells, the approach gives surviving retinal cells a [...]

Scientists engineered stem cell-derived vesicles to deliver tumor-suppressive miR-124 into colorectal cancer cells, silencing EZH2, weakening STAT3 signaling, and shrinking tumors in mice.

A new binding-activated CRISPR–dCas13X imaging platform overcomes plant-specific background noise to track single RNA molecules in living cells, revealing how the flowering signal FT mRNA travels between cells and across grafts.

Caribou Biosciences is ending its off-the-shelf CAR-T programs after failing to fund a phase 3 lymphoma trial. What patients should know.

A Johns Hopkins study shows chronic cigarette smoke exposure reprograms distinct lung stem cell populations through epigenetic changes, determining whether KRAS or TP53 alterations give rise to adenocarcinoma or squamous cell carcinoma.

A new PLOS Digital Health opinion argues that tens of thousands of authorised AI diagnostic tools rest on benchmark accuracy figures that say little about real patient benefit, and calls for prospective clinical validation, subgroup performance disclosure, and clinician co-design as prerequisites for deployment.

CBS News: A look at a 1,700-member Slack run by Medicare agency CMS where Microsoft, OpenAI, and other companies help shape policy on AI apps and medical records access  —  A cadre of elite techies, financiers, and high-level Trump administration officials have spent a year quietly charting an extraordinary …

A new study shows that an interpretable AI model fusing 18F-PSMA-1007 PET/CT and multiparametric MRI can predict prostate cancer aggressiveness before surgery with high accuracy.

Researchers developed EntQA, a reference-free, entity-centric metric that scores how faithfully large language models preserve clinically relevant concepts in medical question answering.

A new machine learning method called DCSE predicts side effects of drug combinations and introduces more realistic evaluation standards that expose weaknesses in existing benchmarks.

Researchers have developed a dual-stream convolutional neural network that fuses RGB imagery with vectorized Error Level Analysis and CBAM attention to localize image forgeries such as splicing and retouching.

A Chonnam National University study found that the human dental pulp stem cell secretome reduced oxidative stress and neuroinflammation while restoring motor and cognitive function in a mouse model of ischemic stroke.

Researchers converted Duchenne patient stem-cell teratomas into humanized models in which both gene-corrected cell transplants and lipid nanoparticle base editing restored dystrophin, with full-length recovery depending on muscle maturation.

In general, people who eat a healthy diet give themselves a significantly better chance of avoiding some major diseases than those who don't. The Nordic diet, also known as a northern version of the Mediterranean diet, is a healthy, sustainable way of eating based on traditional foods of countries like Norway, Sweden, Denmark and Finland. It includes plant foods and berries, whole grains, low-fat dairy products and fatty fish.

Japanese researchers used whole-genome sequencing to identify a new mycobacterial species, Mycobacterium meguroense, causing lung disease in a cord blood transplant recipient.

Preconditioning stem cells with a defined dose of 660 nm red light reprograms their mitochondria and activates a SOX9-driven chondrogenic program that substantially restores tracheal cartilage structure and mechanical function in rabbits.

A comprehensive BMC Medicine review finds that artificial intelligence and digital health tools show strong potential to transform cardiometabolic care, provided the field addresses real-world validation, algorithmic transparency, privacy, and equitable access.

New research in PLOS Biology shows that zebrafish embryos activate regeneration programs in response to genetic developmental defects, partially buffering the damage they cause.

A KFF Health News probe found tech firms lobbying officials in a CMS-run Slack. What it means for seniors using Medicare-promoted health apps.

A new review confirms that beremagene geperpavec, the first FDA-approved topical gene therapy, significantly improves wound healing in dystrophic epidermolysis bullosa, though long-term durability depends on continued weekly treatment.

A scoping review finds that GPT-4o and DeepSeek-R1 have surpassed the passing threshold on China's national medical licensing examination, while warning that inconsistent evaluation methods still cloud the field.

Vanderbilt surgeons used a cold oxygen flush called REUP to recover donor hearts for children as young as 2 days old. Results are early but promising.