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A new perspective in the Journal of General Internal Medicine argues that clinical note-writing is not just a documentation chore to be automated but a formative practice that shapes physicians' moral attention, clinical reasoning, and practical wisdom.

A Chinese research team combined delta-radiomics from CT scans with clinical data and SHAP-based machine learning interpretation to predict the emergence of the EGFR T790M resistance mutation in lung cancer patients before treatment begins.

A new explainable transformer that combines frequency-domain analysis and topology-aware structural modeling achieves 97.86 percent accuracy in classifying eight retinal disease categories from OCT scans.

A new AI-driven platform could allow people to interact with their medical devices by sending messages using a smartphone application and receiving feedback in real time. Participants in a proof-of-concept study undergoing monitoring for seizures could ask questions about their brain activity, receive personalized alerts, report symptoms and behaviors and help train the system to better recognize seizure-related patterns.

Researchers used CRISPR-Cas9 to knock out the TAPBP gene in human induced pluripotent stem cells, producing cardiomyocytes with sharply reduced HLA class I expression that evaded cytotoxic T cells without triggering natural killer cell attack.

The reframing of mesenchymal stem and stromal cells as regulatory hubs rather than building blocks represents more than a semantic adjustment; it resolves a long-standing puzzle in the field. Early enthusiasm for MSCs in the 1990s and 2000s rested largely

The Oracle Health breach exposed medical records, Social Security numbers and diagnoses of nearly 20 million patients across multiple states.

A senior CMS official says many parts of Medicare's AI-assisted WISeR prior authorization test are not working. See which services it covers and how patients can appeal.

Researchers at Amsterdam UMC report that disrupting the lysosomal enzyme PLA2G15 reduces stress-induced senescence and reshapes BMP phospholipid metabolism in mouse kidney cells.

Researchers preconditioned mesenchymal stem cells with the bacterial peptide plantaricin, producing smaller, protein-rich microvesicles that selectively triggered apoptosis in colon cancer cells while sparing normal kidney cells in laboratory tests.

Pet owners who cannot face losing an animal now have a growing menu of biotech options. They range from longevity drugs to cloning and cryonics. MIT Technology Review laid out the options this week, and questioned whether some of them are wise. Pills for older dogs US startup Loyal is developing three drugs aimed at helping […] This story continues at The Next Web

A randomized study of internal medicine faculty found that physicians rated AI-generated consultation advice as highly as human specialist advice and adopted its recommendations at nearly identical rates regardless of the perceived source.

Mayo Clinic researchers developed an artificial intelligence model that uses routine electronic health record data to predict pancreatic cancer risk up to three years before diagnosis.

A national review led by Penn Medicine reports that 70 percent of U.S. uterus transplant recipients achieved a live birth or ongoing pregnancy, with surgical outcomes improving steadily since 2016.

A comparative study of rats and humans quantifies how somatic polyploidy, proliferation and hypertrophy each contribute to liver regeneration during cirrhosis.

A prospective study shows that amide proton transfer-weighted MRI can noninvasively distinguish lung adenocarcinoma from lung squamous cell carcinoma in patients with spinal metastases, outperforming diffusion-based measures.

A biomimetic nanoreactor coated with senescent stem cell membranes delivers nitric oxide and magnesium while scavenging reactive oxygen species, reversing a vicious cycle of cellular aging and restoring bone formation in aged mice.

A sweeping review in Food Chemistry: X maps how AI, IoT, blockchain and green analytical chemistry could transform veterinary drug residue surveillance across global food chains.

A new study in Cell Death Discovery shows that the conserved mitochondrial protein Mppa maintains the Drosophila testis stem cell niche and drives germ cell differentiation by regulating energy homeostasis in supporting cells.

CRISPR-based synthetic lethal screening has identified the acetyltransferases p300 and CBP as essential chromatin partners for YAP-driven transcription in GNAQ-mutant uveal melanoma, pointing to a new therapeutic target for this hard-to-treat eye cancer.

A new review maps how patient-derived induced pluripotent stem cells and three-dimensional vascular and neurovascular organoids are transforming Moyamoya disease research, capturing the genetic, vascular and neurovascular complexity that conventional models have missed.

Single-cell sequencing reveals that self-derived and donor-derived exhausted T cells in acute myeloid leukemia run on different transcriptional programs, with leukemia stem-like blasts suppressing immunity through MIF, galectin-9, and TGF-β1.

Harvard-led researchers adapted an adult-trained AI model for newborns by training it sequentially on chest x-rays from 30 neonatal intensive care units without sensitive data leaving any hospital.

Çinli professor Syaopin Ren ürək transplantasiyasından sonra bəzi insanların xarakterində dəyişikliklərin müşahidə oluna biləcəyini bildirib. Day.Az xəbər verir ki, onun sözlərinə görə, belə hallar elmi baxımdan dərindən araşdırılmalıdır.

An AI tool called ChromAgeNet identifies aging in blood stem cells by detecting subtle age-related patterns in the 3D organization of chromatin from standard DAPI-stained nuclear images.

A pretransplant blood test for soluble PD-1 identified liver cancer patients at high risk of tumor recurrence after immunotherapy and liver transplantation.

Drug-resistant tuberculosis remains one of the most stubborn obstacles in global infectious disease control, and a new mini review in Molecular Biology Reports argues that the CRISPR-Cas system has become the decisive research tool for understanding how Mycobacterium tuberculosis evades

A Norwegian case series documents ten fatal cases of EBV-driven hemophagocytic lymphohistiocytosis after ATG-conditioned stem cell transplantation.

A human stem-cell model recreates early yolk sac immune development and shows that a single progenitor population can generate specialized tissue-resident macrophages across the brain, liver, heart, and kidney.

DOJ will centralize health care fraud self-disclosures and use AI to find fraud. What changes, what is still unclear, and what patients can do.

Researchers in Thailand have developed an explainable deep learning system that diagnoses five causes of vaginal discharge from smartphone photos taken through a standard light microscope, achieving near-perfect specimen-level accuracy.

A new review maps how artificial intelligence is transforming RNA-targeted drug discovery across both small molecules and oligonucleotide therapeutics.

In one of the largest studies of its kind, Israeli surgeons completed 39 robotic repairs of rare lateral abdominal wall hernias with no conversions to open surgery, one-day hospital stays for most patients, and no recurrences over roughly 14 months of follow-up.

A new opinion article argues that industrial microbiology's factory metaphor and linear metrics are hiding the regenerative value of microbial communities, from resilient activated sludge to purple non-sulfur bacteria that clean wastewater while producing protein and bioplastics.

Artificial intelligence is quietly transforming two of the most intimate fields of medicine: neuroscience and psychology. A new editorial published in Frontiers in Computational Neuroscience by Lei Lu of King's College London, Zhiqiang Huo of Queen Mary University of London,

A UCSF team tracked pentraxin-3 through liver transplant surgery and found that the speed of its rise after reperfusion, not its final level, was associated with early allograft dysfunction.

Turning 100 is unusually common in one Sardinian village, and centuries of records help show that its residents’ remarkable ages are real. Women in Bolotana, a mountain community of about 2,300 people on the Italian island of Sardinia, have an exceptional pattern of survival after age 70. An international study suggests the village could qualify [...]

An algal protein helped scientists reactivate a fear memory in mice, turning light into a tool for testing what specific brain cells do. Scientists who worked out how to control brain cells with light have won this year’s Nobel Prize in Physiology or Medicine. Karl Deisseroth, Peter Hegemann, and Georg Nagel were honored for their [...]

Researchers at the University of Bristol have demonstrated that human brain organoids can classify all 26 Braille letters with 83 percent accuracy when three organoids work in parallel, using a novel encoding strategy that converts tactile sensor data into electrical stimulation patterns.

Adeno-associated virus (AAV) vectors have become the delivery vehicle of choice for modern gene therapy, carrying therapeutic genes into cells with broad tissue tropism, a favorable safety profile, and durable expression. More than 10,000 rare disorders have been described worldwide,

The appeal of hydrogels in regenerative medicine begins with a deceptively simple physical observation: soft tissues of the human body are largely water. Cartilage, for instance, contains roughly seventy to eighty percent water by weight, while the brain and spinal

Organ transplantation has long been the definitive treatment for end-stage organ failure, but its reach has always been constrained by a stubborn shortage of usable donor organs. For more than half a century, the standard of preservation has barely changed:

A matched real-world study finds that SGLT2 inhibitors in kidney transplant recipients deliver modest weight loss and stable potassium without new safety signals, while revealing that drug-induced glucosuria can inflate albuminuria readings measured by the Jaffé method.

Three clinical cases suggest that a multimodal peptide-based protocol may support neurosensory recovery after inferior alveolar nerve injury, though controlled trials are needed to confirm efficacy.

A new Forum article argues that the design of experimental warm ischemia models, from lung inflation state to split-lung laterality, can determine whether lung grafts appear resilient or vulnerable.

Researchers combined generative AI data augmentation with an intrinsically interpretable machine-learning model to predict perinatal psychological distress among Aboriginal mothers using culturally grounded Baby Coming You Ready assessment data.

A systematic review of 81 studies finds that artificial intelligence is reducing infectious, toxic, and occupational health risks across the entire waste management lifecycle, and argues that institutions must catch up.

A national survey of internal medicine residency program directors reveals that formal education on artificial intelligence remains inconsistent across US training programs even as residents informally adopt generative AI tools.

A new review argues that the longevity enzyme sirtuin 1 sits at the molecular crossroads between cellular senescence and heart failure, offering a mechanistic target for next-generation therapies.

A new review showcases how low-cost robotic canes, AI-based diabetic foot screening, and simple EEG analysis tested in real-world clinical settings could make rehabilitation technology affordable and accessible.

A case-level audit of a public thyroid imaging archive finds contradictory labels, leak-prone data splits, and strong evidence that deep learning models exploit acquisition artifacts rather than lesion features alone.

A new report traces how federal brain-death legislation, a national procurement center, and a landmark organ-sharing pact with Kuwait transformed the UAE from a transplant desert into one of the world's fastest-growing deceased donation programs.

Transplant medicine is quietly undergoing one of its most profound conceptual shifts in decades. Writing in Frontiers in Transplantation, a team of physicians from Geneva University Hospitals and Swisstransplant argues that abdominal normothermic regional perfusion, or A-NRP, should no longer

A vision-based machine learning study of 61 dementia care residents found that ceiling-mounted cameras and gait analysis could detect gait severity changes associated with acute antipsychotic dose reduction, though paired analyses revealed heterogeneous individual responses.

GERBase offers freely queryable, family-phased high-resolution HLA allele and haplotype frequencies with linkage disequilibrium metrics from 17,260 Brazilian transplant candidates, closely matching the national donor registry and supporting allele dropout detection, virtual crossmatching, and donor prioritization.

A study of arginine/tryptophan peptides shows that strong carrier-cargo binding blocks gene silencing, and adding a negatively charged component restores siRNA activity and CRISPR/Cas9 editing by promoting intracellular release.

A new dual-modality deep learning framework called DHF-DTI combines sequence and graph data with cross-attention fusion and supervised contrastive learning to predict drug-target interactions more accurately across cross-domain and cold-start scenarios.

For millions of people living with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, the search for answers has been a frustrating one. The condition, characterized by debilitating fatigue, post-exertional malaise, chronic muscle pain and weakness, has no validated biomarkers, no effective treatments, and

Cate Lawrence / Tech.eu: London-based Scarlet, which certifies AI and software for medical devices, raised a $50M Series B led by Headline to support its US and Asia-Pacific expansion  —  Led by Headline, the funding will support the London-based company's expansion into the US and Asia-Pacific as it tackles lengthy …

Scientists have long suspected that aging leaves chemical fingerprints on the DNA packaging inside our cells. Now a team at the University of Turin has captured those fingerprints in unprecedented detail across the lifespan of the mouse brain, and what

As five-year survival rates for transplant recipients now exceed 90%, researchers argue that graft survival alone no longer defines success. A new perspective in Transplant International calls for qualitative research on patient-reported outcomes, quality of life, and lived experience to become a central pillar of patient-centered transplant care.

The 30th ILTS Congress in Singapore showcased robotic donor surgery, machine perfusion biomarkers, AI-driven prediction and xenotransplantation milestones, revealing a liver transplant field at a genuine inflection point.

Artificial intelligence has long been accused of being a black box, especially in medicine, where a wrong answer can change a life. Now a research team spanning Pakistan, Saudi Arabia and the United Kingdom has built an AI system that

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Mark Wahlberg, who once sank money into a gym chain that got kicked off the NYSE, is now building his own, and he promises you’ll get a cold plunge, a blood panel and a protein muffin without needing a trust fund.

New research shows CD4+ T cells kill the progenitor cells needed to rebuild bone after injury, while regulatory T cells protect them—revealing an immune balancing act that shapes mammalian tissue regeneration.

A University of Tokyo feasibility study finds that AI-based throat imaging for influenza could overcome the biological sampling bottleneck that has long limited fully remote diagnosis, provided four conditions on access, accuracy, usability, and treatment integration are met.

A Chinese-developed sequencing assay measuring donor-derived cell-free DNA identified a 0.33% threshold for detecting acute rejection in heart transplant recipients, offering a noninvasive alternative to biopsy.

Clinicians at Helsinki University Hospital describe how they evaluate the minds of face and hand transplant candidates, proposing mentalization as a key lens for predicting who will thrive after surgery.

A decade-long scoping review of 93 AI health studies finds that only 12.9 percent implemented concrete equity measures and just 6.5 percent involved people with disabilities in co-design or validation, despite the technology's potential to transform their lives.

A machine learning-derived composite biomarker built from twelve routine clinical measurements predicted waitlist mortality and transplantation in liver transplant candidates more accurately than MELD scores measured at initial evaluation.

A seven-year study of over 14,000 Chinese adults finds that combining online and offline social activity is associated with slower cognitive decline and frailty progression in middle-aged and older people.

A new review argues that AI-driven antiviral discovery must be benchmarked against respiratory RNA virus polymerases under virologically realistic conditions rather than relying on docking scores and general protein-ligand datasets.

Machine learning is accelerating target identification, toxicity prediction and drug repurposing, but researchers insist algorithmic discoveries still demand rigorous experimental validation.

Frontiers in Neuroscience has retracted a 2018 study on microRNA Let-7f-5p and stem cell survival in Alzheimer's disease models after image integrity concerns and the authors' failure to provide complete raw data.

A new review shows that hybrid deep learning and swarm-optimized AI models are achieving near-perfect prediction of lithium-ion battery charge, health, and remaining lifespan for electric vehicles and grid storage.

Researchers used a vector-free CRISPR activation system to boost dopamine biosynthesis genes in cellular models of Parkinsonian neurotoxicity, finding modest DDC upregulation, no GCH1 activation, and no added toxicity.

The journal Pathology & Oncology Research has retracted a 2018 osteosarcoma study after the authors reported improper image cropping, with an investigation confirming the findings are no longer supported by the data.

Researchers have built and validated a GMP-compliant, semi-automated manufacturing platform that produces clinical-grade extracellular vesicles from Wharton's jelly-derived mesenchymal stromal cells with consistent quality and one-year frozen stability.

A large two-center study finds that a low donor PaO2/FiO2 ratio raises the risk of early primary graft dysfunction after lung transplantation without affecting two-year survival.

A University of Toronto-led team will use a $2.3 million Google.org award to build OpenPep, an open-access database and AI platform for predicting peptide-protein interactions in drug discovery.

The largest cohort study to date finds that kidney transplants from donors with thin basement membrane disease perform as well as those from donors with normal biopsies, offering new reassurance for living donation programs worldwide.

After a Chrome clone was spotted on the Play Store earlier this week, a user on Reddit says they're seeing a fake version of WhatsApp in a "sponsored" slot above the real version. As reported earlier by Android Authority, the WhatsApp dupe has racked up over 500,000 downloads and, at the time of writing, its Play Store listing is still live. Google did not immediately respond to a request for comment. The WhatsApp clone is from a developer going by "Agment Assets sallu" who doesn't currently have anything else listed on the Play Store. Their listing for the WhatsApp impostor has the same icon, screenshots, and text as the real version, but … Read the full story at The Verge.

In a study of fingertip regeneration, a team led by JAX senior research scientist James Godwin found that some immune cells in mice can attack and kill cells needed to rebuild bone, while a subset of those same immune cells can protect the bone-making cells and allow regeneration to continue.

A new GeroScience study shows that the dietary polyphenol chlorogenic acid protects aging intestinal stem cells from oxidative stress in fruit flies through a mechanism requiring CncC, the fly counterpart of the mammalian NRF2 pathway.

Actor and angel investor Mark Wahlberg says he's OK with using AI in filmmaking, provided it's used "to enhance what you're doing."

New research illustrates the rapid rise of clinicians’ use of AI to answer medical questions despite little evidence of how it affects decision-making or patient outcomes. Researchers studied usage data from OpenEvidence, an AI search ...

The virus used to deliver healing DNA in gene therapy is under renewed scrutiny.

→ More former Genentech leaders are finding a new home. Lélia Delamarre posted on LinkedIn that she’s leading R&D at ARCH-backed cancer biotech Medici Therapeutics, one of this year’s

Older age, baseline oxygen use, and lower respiratory tract symptoms signal worse outcomes among hospitalized lung transplant recipients with respiratory syncytial virus infection.

Hungarian researchers have built a human induced pluripotent stem cell platform that reproduces the sensitivity of healthy dividing tissues to chemotherapy, revealing that stem cells and neural progenitors are far more vulnerable to anticancer drugs than conventional cancer cell lines suggest.

As major health systems open their own programs, longevity medicine is gaining credibility and becoming more accessible.

arXiv:2608.02712v2 Announce Type: replace Abstract: Kernel generation for hardware accelerators such as GPUs and NPUs has become a proving ground for large language models (LLMs), and state-of-the-art systems raise correctness through pipelines that couple LLMs with agentic reinforcement learning and evolutionary search. Such pipelines generate, compile, and execute large numbers of candidate kernels, discarding most of them and forgoing the opportunity to distill failures into reusable knowledge. Many discarded candidates are near-miss operators that compile and run but fail numerical validation; each embodies genuine domain knowledge and a nontrivial investment in LLM inference, cross-compilation, and hardware execution. We argue for a paradigm shift: rather than regenerate, debug. Debugging is far more constrained than generating from scratch: the search space is small and feedback is dense. We present a domain-specific debug agent that addresses three core challenges in autonomous

arXiv:2610.21402v1 Announce Type: new Abstract: Optical Wireless Communication (OWC) systems provide high-bandwidth, spatially secure, and RF-interference-free digital transmission. However, direct free-space optical links suffer from extreme sensitivity to line-of-sight disruptions, optical attenuation, high ambient light saturation, and transmitter-receiver misalignment. Traditional channel diagnostic frameworks rely on external computing nodes or cloud-based processing, which introduces severe diagnostic latency and reduces edge node autonomy. This paper presents an autonomous, self-diagnosing optical wireless receiver node that integrates physical-layer signal telemetry extraction with an on-device TinyML classification engine. Built around an ESP32-S3 microcontroller, the receiver recovers 1000 bit/s On-Off Keying (OOK) digital payloads using a 5-sample majority voting mechanism while concurrently extracting real-time channel features: Bit Error Rate (BER), received signal

Li Renke, a visionary cardiovascular scientist who applied engineering principles to the human heart and developed conductive biomaterials to repair tissue damaged by heart attacks, died while attending an academic conference in the Chinese city of Xian earlier this month. He was 65. His death on October 10 was announced by The Chinese University of Hong Kong, Shenzhen (CUHK-Shenzhen), where he was presidential chair professor and associate dean of research and translation at the school of...

A multicenter Chinese study shows that an MRI-based nomogram combining clinical signs with AI-derived tumor habitat features can noninvasively predict high-risk hepatocellular carcinoma before surgery and stratify patients' risk of recurrence.

A YOLOv8-based deep learning model identified and measured children's coronary arteries on echocardiograms with expert-level accuracy in under two seconds per measurement.

A Columbia Nursing survey of 1,185 U.S. adults found that 63 percent would not endorse AI-generated medical responses without clinician review, though most accepted fast AI replies for logistical tasks.

A new study reports that exosomes released by inflamed synovial stem cells carry the circular RNA circRNF20, which worsens rheumatoid arthritis by activating a TLR4, neutrophil trap, and interleukin-6 signaling pathway.