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Johns Hopkins University engineers have created robots the size of a pencil tip intended to travel through the body to deliver medicine to infections inside a beating heart.

Northwestern Medicine scientists have identified a stem-like state in small-cell lung cancer that distinguishes a group of patients with exceptionally poor outcomes following chemoimmunotherapy, according to a study published in Cell Reports Medicine.

Apple TV today announced “Heart,” an original eight-episode true-crime podcast involving two men linked by a donated heart and the same terrible demise. Here are the details. more…

Women who stay on aromatase inhibitors for 5 years have higher risks of hypertension, dyslipidemia, and diabetes vs their non-adherent counterparts. Yet their mortality rate is lower.

A Harvard-led study of more than 1,300 pregnancies found that a Mediterranean-style prenatal diet and regular seafood consumption were associated with significantly lower infant risk of colic and eczema.

Cancer incidence after solid organ transplant varies significantly based on transplant and malignancy type.A study of more than 620,000 patients who received heart, kidney, liver or lung transplant showed that patients who had lung transplants had the greatest incidence rates for solid tumors, nonmelanoma skin cancer and posttransplant lymphoproliferative disorder (PTLD).Additionally, bladder, colorectal, genital and lung cancer incidence increased over time, whereas melanoma, thyroid cancer and PTLD rates dropped after high early incidence.“This is something we should be more observant of,

If you are planning to buy a Shelby Mustang, there are a few key things to look out for to ensure you are not getting a clone or fake car for a premium price.

Cells become senescent in response to stress and damage, in response to tissue injury, but most commonly upon reaching the Hayflick limit to replication. A senescent cell ceases to replicate, grows in size, and generates a potent mix of pro-growth, pro-inflammatory signals. Senescent cells are created throughout life in tissues throughout the body, but an established population of lingering senescent cells only begins to accumulate in later life. In youth, the immune system efficiently clears senescent cells, allowing senescence to be a beneficial state in the coordination of regeneration and in drawing the attention of the immune system to potentially cancerous cells. In later life, the immune system falters in this task. An established population of senescent cells that generates signaling constantly, even in relatively […]

Donor organs are exceedingly scarce, so much so that one in five people on the waiting list for a heart transplant in the U.S. dies or is removed from the list before receiving a transplant.

Researchers report the first CRISPR/Cas12a editing of sugarcane, showing that co-expressing the mTREX2 exonuclease boosts large deletions seven-fold and enables efficient multiallelic editing of the lw1 gene in the crop's highly polyploid genome.

A fusion of CT-based habitat radiomics and 3D deep learning predicted the hidden STAS invasion pattern in early-stage lung adenocarcinoma with an AUC of 0.824 before surgery.

A new review in Current Research in Food Science details how artificial intelligence, CRISPR gene editing and RNA interference are converging to cut the 25 to 50 percent of fruits and vegetables lost after harvest each year.

Donor organs are exceedingly scarce, so much so that one in five people on the waiting list for a heart transplant in the U.S. dies or is removed from the list before receiving a transplant.

InvestorPlace - Stock Market News, Stock Advice & Trading Tips Neuralink is private, but Butterfly Network and Quantum-Si offer two very different public-market angles on brain-computer interfaces. The post 2 Brain-Computer Interface Stocks to Watch While Neuralink Stays Private appeared first on InvestorPlace.

Google has taken a stake in Flo Health, the period-tracking app, the companies said on Monday. The multi-year deal will bring women’s health data into Google’s wearables and coaching. They did not disclose the size of the investment. From early 2027, users will be able to sync Flo with the Google Health app, Engadget reported. Fitbit readings such as […] This story continues at The Next Web

Google's Sleek New Fitbit Edge Is Packed With Health Features And A Replaceable Battery  EngadgetGoogle Fitbit Edge: Our all-new smartest fitness tracker ever  blog.googleGoogle Debuts $180 Fitbit Edge Tracker in Continued Health Push  Bloomberg.comGoogle announces the Fitbit Edge, a middle ground between Pixel Watch 5 and Fitbit Air  Ars TechnicaThe Fitbit Edge is for folks who don’t want to go totally screenless  The Verge

Google's Sleek New Fitbit Edge Is Packed With Health Features And A Replaceable Battery  EngadgetGoogle Fitbit Edge: Our all-new smartest fitness tracker ever  blog.googleGoogle Debuts $180 Fitbit Edge Tracker in Continued Health Push  Bloomberg.comGoogle announces the Fitbit Edge, a middle ground between Pixel Watch 5 and Fitbit Air  Ars TechnicaThe Fitbit Edge is for folks who don’t want to go totally screenless  The Verge

A Chinese clinical study reports that donor-derived anti-CD19 CAR-T cells achieved complete remissions in 13 of 14 patients whose B-cell acute lymphoblastic leukemia relapsed after stem-cell transplantation, including most patients with extramedullary disease.

New research reveals that the Hippo pathway effector YAP1 acts as a master switch controlling whether adult spinal cord stem cells become myelin-producing oligodendrocytes or scar-forming astrocytes.

Cheyenne MacDonald / Engadget: Google says Health Guardian is launching later in October on the Fitbit Air and Edge for Google Health Premium users, and expands automatic activity tracking  —  The company also announced a new metal mesh band for the Fitbit Air.  —  Google is rolling out a pair of updates …

Researchers discovered that the RNA-modifying enzyme PUS7 pseudouridylates the noncoding RNA 7SK to recruit the BAF chromatin-remodeling complex, enabling a new OCT4-free recipe for making high-fidelity human iPS cells.

Johns Hopkins engineers have developed wireless, magnetically steered millirobots that travel through the bloodstream to dock on a beating heart and deliver antibiotics directly to infected tissue, potentially replacing weeks of IV therapy or open-heart surgery.

arXiv:2608.28620v2 Announce Type: replace Abstract: Preference elicitation is essential for aligning AI systems with human values. Prior approaches (e.g., for organ allocation) often ask stakeholders to compare the decisions of an algorithm (e.g., patient A vs. patient B). Such a decision-level approach conflates the means with the ends. Instead, we elicit preferences directly over allocation outcomes to learn a utility function for policy optimization. We construct a novel preference elicitation algorithm for linear utilities that outperforms prior techniques in practice. Our algorithm has two phases. The first phase learns cutting planes through pairwise comparisons to rapidly shrink the space of possible attribute weights and warm-starts the second phase by eliminating dominated regions. The second phase then provably converges to the user's utility function. We apply our technique to heart transplant allocation, where a policy must balance competing objectives such as

arXiv:2610.13894v1 Announce Type: new Abstract: Nimbus Studio is a visual pipeline platform for brain-computer interface (BCI) experiments: researchers assemble preprocessing, feature extraction, decoding, and evaluation over public benchmark datasets or their own recordings, with cross-validated evaluation protocols (including leave-one-subject-out), BIDS export, and bring-your-own Python model classes. Whether its numbers can be trusted is a fair question for any such platform. We answer it with a parity study: six standard BCI decoding pipelines (CSP+LDA, Riemannian MDM, tangent-space logistic regression through the platform's bring-your-own-code node, P300 xDAWN+LDA, and the deep ShallowConvNet and EEGNet) were evaluated on three public datasets (motor-imagery BNCI-2014-001/004; P300 BNCI-2014-009) under two protocols (per-subject session holdout and pooled leave-one-subject-out cross-validation via the platform's planned-CV driver), once through Nimbus Studio's execution engine

arXiv:2610.13054v1 Announce Type: new Abstract: Recently, generative neural synthesizers have enabled zero-shot instrument cloning from reference recordings and timbre generation from text prompts. However, existing systems generate complete audio segments offline, precluding their use as playable instruments. We present LiveSynth, a streaming neural synthesizer with flexible timbre control and interactive generation capabilities, including zero-shot instrument cloning and text-to-instrument synthesis. A feedback-free causal Transformer conditioned on MIDI events and a CLAP timbre embedding outputs continuous audio latents at 100 Hz, which a causal variational autoencoder decodes into audio. Frame-wise timbre conditioning enables continuous timbre morphing, while MIDI-conditioning dropout enables autonomous continuation from a performed prefix. On the NSynth and Slakh datasets, LiveSynth achieved timbre similarity and spectral reconstruction quality comparable to offline baselines. On

A Chinese research team has shown that machine learning analysis of tumor sub-regions and surrounding tissue on non-contrast CT scans can accurately distinguish benign from malignant sacral tumors before surgery.

Researchers developed a 20-item scale for judging biological meaning in health-related images and showed that multimodal AI models can apply it with high consistency, though day-to-day stability and one subscale need work.

A four-week smartphone-based education program for mothers significantly and sustainably improved parent-reported quality of life in pediatric heart transplant recipients, outperforming face-to-face teach-back instruction, according to a new quasi-experimental study published in BMC Pediatrics.

A field study in China's Loess Hilly Region finds that mixed pine and black locust plantations are more stable than pure stands, but weak natural regeneration threatens their long-term persistence.

Peter Hegemann, Georg Nagel and Karl Deisseroth turned a light-sensitive protein from algae into a tool for switching brain cells on and off, giving the study of emotion, memory and behavior a causal, material basis. The prize comes as the Trump administration guts the research and health care this science should serve.

In a Lancet study, Google's AMIE AI interviewed 98 patients before urgent visits with no safety stops. What doctors measured and what it cannot prove.

A new review charts how stem cell transplantation, lentiviral gene therapy, and CRISPR-based editing such as Casgevy are turning beta-thalassemia from a lifelong transfusion-dependent illness into a potentially curable disease, while cost and access hurdles remain steep.

Sea cucumber tissue kept growing for more than three years after removal, surviving in seawater teeming with microbes. Like Thing, the disembodied hand in The Addams Family, a severed piece of sea cucumber tissue kept living without the body it came from, prompting scientists to describe the animal as a “real-life zombie.” Weeks after being [...]

A quantitative analysis of 42 medical AI policies from seven major economies finds strong strategic vision but weak implementation tools, with only two policies earning a top-grade rating.

A multimodal deep learning model combining MRI scans with clinical data classifies Alzheimer's disease stages with up to 95 percent accuracy, offering a promising path toward earlier diagnosis.

Researchers have linked 3D-printed collagen scaffolds, scaled-up stem cell expansion, and perfusion bioreactor cultivation to grow large, mineralized bone constructs without exogenous growth factors.

A multi-omics study has mapped stage-specific lipid remodeling across human stem cell differentiation into cardiomyocytes, revealing that polyunsaturated phospholipids accumulate as cells mature and that phosphatidylcholine supplementation modulates maturation and hypertrophy gene programs.

A gut bacteria-derived bile acid called hyodeoxycholic acid restores aging bone marrow stem cells and reverses bone loss in a mouse model of postmenopausal osteoporosis by activating a TGR5-ESR1 mitophagy pathway.

New cell research shows prolonged tadalafil exposure boosts proliferation of muscle progenitor cells, suppresses myostatin and TGF-beta, and delays terminal differentiation, suggesting therapeutic promise for muscle-wasting disorders while raising anti-doping concerns.

A single-cell multi-omic atlas of neuroendocrine carcinoma of the cervix identifies DLL3 as a driver of immune evasion and validates DLL3-targeted therapy in patient-derived organoid models.

Clinicians in Chongqing report an extremely rare case in which Bartonella henselae bacteremia from a kitten scratch triggered hemophagocytic lymphohistiocytosis in a kidney transplant recipient, diagnosed by metagenomic sequencing and successfully treated with short-course antibiotics and immunomodulatory therapy.

A new metabolomic study shows that mouse retinal organoids share 148 of 166 detected metabolites with native retina, yet reveal selective immaturity in glycolytic, TCA cycle, and amino acid metabolism that points the way to better culture conditions.

Researchers have built a multilingual transformer-based AI system that diagnoses crop diseases, generates farming advice, and delivers market intelligence while sustaining 10,000 concurrent users at 0.35 seconds per query.

Researchers in Shandong, China, have developed and externally validated machine learning models that use preoperative data to predict complications, prolonged hospital stay, and postoperative pain in patients undergoing surgery for thymic epithelial tumors.

A multicenter study found that a deep learning model analyzing full ultrasound videos significantly improved diagnostic accuracy for suspicious breast lesions, lifting junior sonographers' accuracy from 66.7% to 89.2%.

A prospective Polish study shows that patients who develop graft-versus-host disease in the first six months after allogeneic stem cell transplantation suffer persistently worse fatigue and quality of life, with fatigue emerging as a strong, potentially modifiable driver of patient well-being.

Critical Path Institute and the University of Arizona have launched a two-year collaboration using human stem cell-derived neurons and new approach methodologies to uncover the sex-specific cellular biology of Parkinson's disease in women.

Scientists have demonstrated a promising new approach to restoring limited vision in people with advanced inherited blindness. An experimental treatment combining gene therapy with specialized goggles has helped some people with advanced blindness detect objects and respond to visual cues. Instead of attempting to repair damaged light-sensing cells, the approach gives surviving retinal cells a [...]

Scientists engineered stem cell-derived vesicles to deliver tumor-suppressive miR-124 into colorectal cancer cells, silencing EZH2, weakening STAT3 signaling, and shrinking tumors in mice.

A new binding-activated CRISPR–dCas13X imaging platform overcomes plant-specific background noise to track single RNA molecules in living cells, revealing how the flowering signal FT mRNA travels between cells and across grafts.

Caribou Biosciences is ending its off-the-shelf CAR-T programs after failing to fund a phase 3 lymphoma trial. What patients should know.

A Johns Hopkins study shows chronic cigarette smoke exposure reprograms distinct lung stem cell populations through epigenetic changes, determining whether KRAS or TP53 alterations give rise to adenocarcinoma or squamous cell carcinoma.

A new PLOS Digital Health opinion argues that tens of thousands of authorised AI diagnostic tools rest on benchmark accuracy figures that say little about real patient benefit, and calls for prospective clinical validation, subgroup performance disclosure, and clinician co-design as prerequisites for deployment.

CBS News: A look at a 1,700-member Slack run by Medicare agency CMS where Microsoft, OpenAI, and other companies help shape policy on AI apps and medical records access  —  A cadre of elite techies, financiers, and high-level Trump administration officials have spent a year quietly charting an extraordinary …

A new study shows that an interpretable AI model fusing 18F-PSMA-1007 PET/CT and multiparametric MRI can predict prostate cancer aggressiveness before surgery with high accuracy.

Researchers developed EntQA, a reference-free, entity-centric metric that scores how faithfully large language models preserve clinically relevant concepts in medical question answering.

A new machine learning method called DCSE predicts side effects of drug combinations and introduces more realistic evaluation standards that expose weaknesses in existing benchmarks.

Researchers have developed a dual-stream convolutional neural network that fuses RGB imagery with vectorized Error Level Analysis and CBAM attention to localize image forgeries such as splicing and retouching.

A Chonnam National University study found that the human dental pulp stem cell secretome reduced oxidative stress and neuroinflammation while restoring motor and cognitive function in a mouse model of ischemic stroke.

Researchers converted Duchenne patient stem-cell teratomas into humanized models in which both gene-corrected cell transplants and lipid nanoparticle base editing restored dystrophin, with full-length recovery depending on muscle maturation.

In general, people who eat a healthy diet give themselves a significantly better chance of avoiding some major diseases than those who don't. The Nordic diet, also known as a northern version of the Mediterranean diet, is a healthy, sustainable way of eating based on traditional foods of countries like Norway, Sweden, Denmark and Finland. It includes plant foods and berries, whole grains, low-fat dairy products and fatty fish.

Japanese researchers used whole-genome sequencing to identify a new mycobacterial species, Mycobacterium meguroense, causing lung disease in a cord blood transplant recipient.

Preconditioning stem cells with a defined dose of 660 nm red light reprograms their mitochondria and activates a SOX9-driven chondrogenic program that substantially restores tracheal cartilage structure and mechanical function in rabbits.

A comprehensive BMC Medicine review finds that artificial intelligence and digital health tools show strong potential to transform cardiometabolic care, provided the field addresses real-world validation, algorithmic transparency, privacy, and equitable access.

New research in PLOS Biology shows that zebrafish embryos activate regeneration programs in response to genetic developmental defects, partially buffering the damage they cause.

A KFF Health News probe found tech firms lobbying officials in a CMS-run Slack. What it means for seniors using Medicare-promoted health apps.

A new review confirms that beremagene geperpavec, the first FDA-approved topical gene therapy, significantly improves wound healing in dystrophic epidermolysis bullosa, though long-term durability depends on continued weekly treatment.

A scoping review finds that GPT-4o and DeepSeek-R1 have surpassed the passing threshold on China's national medical licensing examination, while warning that inconsistent evaluation methods still cloud the field.

Vanderbilt surgeons used a cold oxygen flush called REUP to recover donor hearts for children as young as 2 days old. Results are early but promising.

A gene therapy plus camera goggles helped 7 of 10 people with advanced retinitis pigmentosa see more light, but none regained normal sight.

Researchers show that an unmodified large language model can screen and extract data from digital health trial reports with human-level agreement, pointing toward faster systematic reviews.

Google Health 5.10 is rolling out as a smaller update this week with a trio of new features across the app. more…

New research shows that chronic intracellular calcium overload keeps muscle progenitor cells proliferating through sustained NFATc1 signaling, impairing regeneration, and that NFAT inhibition can restore myogenesis in cell and animal models.

A team at Nanjing Medical University used RFdiffusion to design a CLDN18.2-targeting T-cell engager for gastric cancer and showed that dendritic-cell supplementation via IL-12 and CXCL9/CXCL10 signaling is needed for durable antitumor responses.

Researchers have discovered Δ246p53, a conserved 18-kilodalton p53 isoform translated from codon 246 that responds to DNA damage and enhances p53 family-driven senescence through interactions with full-length p53 and ΔNp63.

A new mouse study shows that bone marrow mesenchymal stem cells treat chemotherapy-induced premature ovarian failure by rebalancing the Bcl2/Caspase3 apoptosis pathway, restoring follicles and hormone levels.

Gene therapies are used to treat many different blood disorders. However, blood stem cells often fail to achieve their full potential after transplantation.

New research shows that gamma irradiation drives p53 wild-type medulloblastoma cells into a senescent state that senolytic drugs such as Navitoclax and Copanlisib can then selectively eliminate, suggesting a way to reduce the side effects of craniospinal radiotherapy in children.

The Essential Cycles of Regenerative Agriculture The Real Cost of Not Knowing Regenerative agriculture has done a lot of good for a lot of operations, but somewhere along the way it also turned into a marketing word. Biological inoculants. Soil-boosting amendments. Proprietary blends with names that sound like they were focus-grouped by a pharmaceutical company. […] The post The Essential Cycles of Regenerative Agriculture appeared first on Understanding Ag.

A Texas filing puts Oracle Health's 2025 Cerner breach at nearly 20 million people. See what data was exposed and what patients should check now.

A new bioinformatic study in Reproductive Sciences shows that a risk model built from telomere-related senescence genes can independently predict survival outcomes in cervical cancer patients.

Perficient has launched an AI suite to help Medicare Advantage plans raise their CMS star ratings, which decide access to more than $13B a year in federal bonus payments. It arrived a day after CMS published 2027 ratings showing fewer plans qualifying, and the consultancy is owned by Swedish buyout group EQT. Perficient has launched […] This story continues at The Next Web

Researchers from the University Hospital of Bonn and the University of Bonn have succeeded in dramatically rejuvenating human cells in a test tube. To do so, they directly reprogrammed red blood cell precursors into stem cells from which neurons can be derived. During this process, the molecular clocks that indicate a cell's age were reset. For example, blood cells from an 80-year-old were transformed into stem cells with a molecular age of less than 20 years.

NYU Langone ophthalmology researchers presented trial evidence that a ROCK inhibitor eyedrop can spare corneal transplants, staged therapies for corneal neovascularization, hidden vitamin A deficiency cases, and progress toward whole-eye transplantation at the AAO 2026 meeting.

This guide is built to make that decision easier. We spent months researching the top 10 hair transplant clinics in Turkey, analysing thousands of verified reviews, and cross-checking surgeon credentials against ISHRS and JCI databases. The result is an independent ranking of the top 10 hair transplant clinics in Turkey.

A study of 414 undergraduates at Arsi University finds 70 percent use generative AI tools like ChatGPT for self-diagnosis and self-medication, with digital literacy and weak health-seeking behavior among the key drivers.

Biomedical engineers at Duke University have developed a three-layer model of human blood vessels that enables researchers to better understand how Hutchinson-Gilford progeria syndrome (HGPS), a rare genetic disorder that causes accelerated aging, affects the vascular system.

Scientists have engineered human stem cell-derived spheroids containing myelinating oligodendrocytes and reactive microglia that model demyelination and successful remyelination, offering a drug-screening platform for multiple sclerosis therapies.

Nvidia commits $1 billion over five years to support US science, quantum computing and AI research, expanding its role in the federal Genesis Mission. The post Nvidia’s $1 Billion Research Plan Targets AI, Quantum Computing and Medicine appeared first on TechRepublic.

A scoping review of 19 studies finds that multimodal AI fusing raw images with non-image data in mental and cognitive healthcare is dominated by a single dataset, intermediate fusion strategies, and very little real-world clinical validation.

Blood stem cells are rare cells in the bone marrow that produce the blood and immune cells needed throughout life, ensuring that the body's blood and immune system are renewed. This is why they are also used in bone marrow transplants and novel gene therapies for treating a range of blood disorders. However, during gene therapy, the stem cells need to be processed in the laboratory before transplantation, which can cause them to lose some of their regenerative capacity and reduce the chance of the overall treatment being successful.

An explainable generative deep learning framework called SYNERGY-VAE has uncovered three hidden population subgroups with distinct health signatures and depression prevalence ranging from 6.8 to 10.9 percent, enabling more accurate subgroup-specific risk prediction.

New research shows that the bile acid receptor FXR coordinates monocyte recruitment and Kupffer cell proliferation through CCR2 and CSF1/PI3K/Akt signaling, making the receptor and its macrophage targets a promising therapeutic axis for enhancing liver regeneration.

As more people turn to AI chatbots for quick, 24/7 medical advice, a new perspective paper co-authored by faculty at Binghamton University, State University of New York, explores the risks of this practice that are largely invisible to users—and health care systems.

Researchers at ETH Zurich and Roche have combined active learning with geometric and self-supervised deep learning to predict C–H borylation regioselectivity in drug-like molecules, correctly identifying borylation sites on all ten prospective test substrates.

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. We’re putting too much faith in AI’s ability to say no Today’s AI models are trained to refuse a vast number of prompts. If you ask your chatbot how to poison…

A Nature study shows that alveolar type 2 stem cells migrate across compartmental boundaries and, guided by immune-derived SPP1 and Notch signals from ciliated cells, transdifferentiate into club and ciliated cells to repair injured bronchioles.

Laboratory cultures of three Heterocypris ostracod species have revealed complete developmental sequences from egg to adult, providing crucial reference data for identifying fossil shells and interpreting past environmental change.

After the collapse of the Soviet Union, external forces openly sought to manipulate the newly independent states, Alexander Lukashenko recalled

New research shows that enzyme-digested edible bird's nest amplifies nerve growth factor signaling through the TrkA-ERK1/2-CREB-BDNF pathway, priming PC12 cells to differentiate into neurons.