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The International Society for Stem Cell Research (ISSCR) has submitted a formal response to a Request for Information (RFI) issued by the National Institutes of Health (NIH) regarding its pause on new submissions to the NIH Human Embryonic Stem Cell (hESC) Registry and considerations to reduce reliance on hESCs in federally supported research.

The expanding use of robotic technology in lung transplantation came under scrutiny at the 46th Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation (ISHLT), held from 22–25 April at the Metro Toronto Convention Center in Toronto, ON, Canada.

Advances in pediatric heart care are helping more children survive long enough to receive a transplant—but a critical shortage of donor hearts means too many are still dying while they wait, experts warned at the International Society for Heart and Lung Transplantation (ISHLT) 46th Annual Meeting and Scientific Sessions, held from April 22–25 at the Metro Toronto Convention Center in Toronto, ON, Canada.

As demand for heart transplants continues to far exceed the number of available donor hearts, experts at the 46th Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation (ISHLT) explored a critical question: how should this scarce, life-saving resource be allocated?

Li Bin, a doctor at the First Hospital of Lanzhou University, was among the wave of Chinese consumers who snapped up Apple Mac Mini computers during the country’s frenzied adoption of the OpenClaw artificial intelligence agent earlier this year. The young surgeon from Lanzhou, the capital of northwestern China’s Gansu province, bought one to run the open-source program, using it to develop an app to extract and organise information from doctor-patient conversations and lab report photos into...

Artificial intelligence-powered chatbots are getting pretty good at diagnosing some diseases, even when they are complex.

A major international study involving researchers from The University of Manchester has found that education is one of the strongest predictors of how long people live. Using a new statistical approach to overcome gaps in global data, the research shows that people with more education live significantly longer—even in countries where official records are incomplete. The research is published in the journal Demographic Research.

Gene editing has emerged as a powerful approach for targeting the genetic causes of disease, but getting the editing machinery into the right cells efficiently, safely, and at the scale needed for therapies remains one of the biggest set of challenges in the field.

Regeneron will make its newly approved gene therapy available for free in the U.S. The company hasn't yet decided how much it will charge in other countries.

Regeneron will make its newly approved gene therapy available for free in the U.S. The company hasn't yet decided how much it will charge in other countries.

A few species such as salamanders and zebrafish can regenerate lost limbs and even large sections of internal organs, provided they survive the injury. In comparison, mammals exhibit far less of a capacity for such proficient regeneration as adults, but the actual limits of regeneration vary widely across mammalian species. Spiny mice can regenerate full thickness skin, cartilage, and muscle as well as lost kidney tissue. The MRL mouse lineage can fully regenerate ear tissue, a capacity that was discovered because many researchers use ear notches to label their mice. Ordinary laboratory mice can regenerate the tips of their digits, and so can developing humans. Most such regenerative capacity for most mammals is lost somewhere between birth and adulthood, however. The research community is attempting […]

The FDA has approved Otarmeni, the first-ever gene therapy for genetic hearing loss caused by the OTOF gene, for both pediatric and adult patients after positive results.

Netanyahu says he was successfully treated for prostate cancer  The GuardianNetanyahu says he hid prostate cancer from public because of Iran war  The Washington PostIsrael’s Benjamin Netanyahu says he received treatment for prostate cancer  Al JazeeraNetanyahu Reveals He Had Prostate Cancer and Underwent Radiation Therapy  The New York TimesNetanyahu reveals he quietly underwent treatment for undisclosed prostate cancer  CNN

Netanyahu says he was successfully treated for prostate cancer  The GuardianNetanyahu says he hid prostate cancer from public because of Iran war  The Washington PostIsrael’s Benjamin Netanyahu says he received treatment for prostate cancer  Al JazeeraNetanyahu Reveals He Had Prostate Cancer and Underwent Radiation Therapy  The New York TimesNetanyahu reveals he quietly underwent treatment for undisclosed prostate cancer  CNN

Cystic fibrosis is among the most common, known and studied genetic diseases. It affects over 100,000 people worldwide and reduces life expectancy mainly as it causes lung and respiratory problems. Over the years, scientific research has led to the development of several pharmacological therapies for this disease.

Isomorphic Labs president Max Jaderberg said at WIRED Health in London that the startup has built a “broad and exciting pipeline of new medicines.”

A new set of drugs exploit a recently-revealed weakness in 'zombie-like' – or senescent – cells that could lead to new treatments for cancer and age-associated diseases.

FRIDAY, April 24, 2026 — The eyes are the windows not only to the soul, but also to a person’s health, a new study says.Premature aging of the retina could be a red flag for major diseases like diabetes or heart disease, researchers recently rep...

The new generation of weight loss medicines does an unprecedented job of keeping off the pounds — if people stay on the drugs. Yet numerous studies suggest most of those who start taking GLP-1 drugs quit ...

Researchers have used modified CRISPR to silence the extra chromosome 21 in Down syndrome cells, showing promising preclinical results. The post Modified CRISPR tool targets Down syndrome mutation  appeared first on Labiotech.eu. © Labiotech UG and Labiotech.eu. Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to Labiotech UG and Labiotech.eu with appropriate and specific direction to the original content.

A flagship 900-acre farm in Herefordshire is being lined up as a testbed for the future of British agriculture, as the Duchy of Cornwall lau...

Instagram is testing a new dedicated app that's focused around Snapchat-like photo sharing features. The app, called "Instants," was launched in Italy and Spain yesterday, Business Insider reports, and allows users to send each other disappearing photos that are available for 24 hours and can be viewed only once during that window. The app is currently available on both iOS and Android. Meta hasn't announced if a desktop version will follow, or whether Instants will be launched in other regions, including the US. It resembles the "Shots" instant photo sharing feature that is already baked into Instagram messages (and was later rebranded to … Read the full story at The Verge.

A clinical trial to reverse age-related vision conditions using stem cell treatment could finally deliver on the promise of a major discovery in ageing and regeneration made 20 years ago, says columnist Graham Lawton

For years, calling a phone an “iPhone clone” was the quickest way to dismiss it outright. It meant lazy design, cheap hardware, and an experience that fell apart the moment you actually used it. Early copycats earned that reputation. They borrowed the look of Apple’s iPhone, but none of the substance. Bad displays, laggy performance, […]

Gene editing represents one of the most transformative advances in modern medicine, offering the potential to correct genetic diseases at their source. However, a major obstacle in realizing this potential lies in the effective delivery of gene editing tools into the right cells—efficiently, safely, and in therapeutically relevant quantities. At the forefront of solutions to […]

I don’t need to tell you that AI is everywhere. Or that it is being used, increasingly, in hospitals. Doctors are using AI to help them with notetaking. AI-based tools are trawling through patient records, flagging people who may require certain support or treatments. They are also used to interpret medical exam results and X-rays. A…

US health officials on Thursday greenlit a first-of-its-kind gene therapy to treat a rare form of hereditary hearing loss, a breakthrough that could pave the way for other such hearing impairment treatments.

arXiv:2604.21228v1 Announce Type: new Abstract: We record a Lean-certified theorem package for the four-point Heil--Ramanathan--Topiwala configuration \[ \Lambda=\{0,a,b,\nu\}\subset \R^2, \qquad \Lzero=\Z a+\Z b, \qquad \nu=r a+s b, \] with $a$ and $b$ linearly independent. The principal certified theorem states that if $|\symp(a,b)|>1$ and $1,r,s$ are linearly independent over $\Q$, then for every nonzero $f\in L^2(\R)$ the four vectors \[ f,\qquad \pi(a)f,\qquad \pi(b)f,\qquad \pi(\nu)f \] are linearly independent. A second certified theorem treats the rational-coordinate case $r,s\in \Q$, where the configuration lies in a finer full-rank lattice and linear independence follows from Linnell's theorem. The paper is written in standard mathematical prose. An appendix records the precise Lean certification ledger and the explicit analytic inputs used by the formal development and a download link is provided.

arXiv:2604.21017v1 Announce Type: new Abstract: Autonomous medical robots hold promise to improve patient outcomes, reduce provider workload, democratize access to care, and enable superhuman precision. However, autonomous medical robotics has been limited by a fundamental data problem: existing medical robotic datasets are small, single-embodiment, and rarely shared openly, restricting the development of foundation models that the field needs to advance. We introduce Open-H-Embodiment, the largest open dataset of medical robotic video with synchronized kinematics to date, spanning more than 49 institutions and multiple robotic platforms including the CMR Versius, Intuitive Surgical's da Vinci, da Vinci Research Kit (dVRK), Rob Surgical BiTrack, Virtual Incision's MIRA, Moon Surgical Maestro, and a variety of custom systems, spanning surgical manipulation, robotic ultrasound, and endoscopy procedures. We demonstrate the research enabled by this dataset through two foundation models.

In a groundbreaking advancement set to revolutionize the field of otologic surgery, researchers have developed a highly sophisticated, interaction-aware robotic system designed specifically for minimally invasive transcanal inner ear interventions. This state-of-the-art dexterous robot, meticulously engineered to navigate the intricate and delicate anatomy of the human ear, promises to significantly enhance surgical precision, reduce operative […]

Dong-A ST announced on April 24 that from April 22 to 23, it visited MCM Hospital and Eunpa Basic Care Clinic in Addis Ababa, the capital of Ethiopia, to donate ‘Dr. Noun’ and prescription drugs, and also conducted a sampling of ‘Hykardi’ at Black Lion National Hospital.The donation ceremony was att

APOLLO is a multimodal temporal foundation model trained on 25.2 billion medical events from 7.2 million patients across 33 years of Mass General Brigham records, integrating 28 medical modalities into unified “virtual patient representations.” Across 322 downstream tasks, the model showed strong performance in disease prediction, treatment-response stratification, hospital operations, and patient retrieval, supporting the idea of more computable, data-driven medicine.

Over the weekend, we reported on the Fitbit Air and Google Health. We now have our first look at the Google Health brand. more…

Saffie's mum says Luxturna therapy at Great Ormond Street has been like "someone waved a magic wand".

Researchers at Hannover Medical School (MHH) have developed a method for the efficient production of human immune cells, such as macrophages, in medium-sized bioreactors. These immune cells can be derived from induced pluripotent stem cells and are important for disease research and the development of new therapeutic approaches. The method has now been published in the journal Nature Protocols.

Adipose tissue is far more important for our health than many may realize. It does not merely function as an energy store, but as an active tissue that continuously communicates with the rest of the body. This communication requires a dense network of blood vessels, which supply nutrients and help regulate the body's immune system.

Nexus NeroTech Ventures, a brain-health venture capital fund with $200 million in assets, has shut its doors as of March 31. Importance Rank:  1 read more

A new type of chatbot could reliably help people decide what to do about their symptoms—and do so based on guidance that is both medically sound and easy to understand. The chatbot could help reduce unnecessary hospital visits and ensure that those who need care seek it sooner. A team co-led by engineers at the University of California San Diego published their work in Nature Health.

A combination blood stem cell and pancreatic islet cell transplant from an immunologically mismatched donor completely prevented or cured type 1 diabetes in mice in a study by Stanford Medicine researchers. Type 1 diabetes arises when the immune system mistakenly destroys insulin-producing islet cells in the pancreas. None of the animals developed graft-versus-host disease—in which the immune system arising from the donated blood stem cells attacks healthy tissue in the recipient—and the destruction of islet cells by the native host immune system was halted. After the transplants, the animals did not require the use of the immune-suppressive drugs or insulin for the duration of the six-month experiment.

In a groundbreaking advancement poised to revolutionize the treatment of thoracic aortic aneurysm and dissection (TAAD), researchers have unveiled a novel stem cell approach involving CAR-CD34 (+) hematopoietic stem/progenitor cells produced in vivo. This innovative method, recently published in Nature Communications, presents an unprecedented opportunity to combat one of the most elusive and life-threatening cardiovascular […]

A gene therapy made by Regeneron is the first treatment of its kind approved for genetic hearing loss.

By applying base editing, scientists repaired a cystic fibrosis mutation that is unresponsive to current drugs in cell and organoid models, pointing to a possible treatment for some patients. The post CRISPR Base Editing Repairs Hard-to-Treat Cystic Fibrosis Mutation in Cell Models appeared first on GEN - Genetic Engineering and Biotechnology News.

A groundbreaking advancement in digital health technology has been unveiled by a team of engineers at the University of California San Diego. This innovation takes the form of an AI-driven chatbot explicitly engineered to aid individuals in making well-informed decisions about their health symptoms. By leveraging clinician-validated protocols and sophisticated language processing abilities, this system […]

In a groundbreaking advancement for clinical medicine, researchers have unveiled DxDirector, a sophisticated agentic large language model (LLM) designed to revolutionize the diagnostic process. This novel AI-powered system, developed by Xu, S., Huang, X., Wei, Z., and colleagues, promises to streamline the full spectrum of clinical diagnosis, from patient intake to therapeutic recommendation. Published in […]

During a beautiful, abnormally warm February day this past winter, my two-year-old grandson was looking out the window and pointing at the heifers along my driveway and rambling about “da cows”. I decided to let him see them up close. Like most young, curious, and gentle cattle, they lined up shoulder-to-shoulder and slowly moved closer […] The post Regenerative Farms: Build It, Share It, Leave It appeared first on Understanding Ag.

The U.S. Food and Drug Administration has approved Regeneron's gene therapy for a rare genetic form of ⁠deafness, the company said on Thursday.

Regeneron has won the first ever FDA approval for a gene therapy to treat a rare type of inherited hearing loss, and the company plans to offer the treatment for free in the US, though ...

The treatment, the first of its kind, was approved by the Food and Drug Administration on Thursday. “Our baby was born deaf, and now he can hear,” said one parent.

Gene therapy improves hearing in 90% of patients with inherited deafness in largest trial of its kind  Live ScienceFDA approves first gene therapy for inherited deafness, shown to restore hearing for children with rare condition  CNNFDA Approves First-Ever Gene Therapy to Restore Hearing  WSJMulticentre gene therapy for OTOF -related deafness followed up to 2.5 years  Nature'Impressive' trial results for experimental gene therapy for deafness | STAT  statnews.com

Gene therapy improves hearing in 90% of patients with inherited deafness in largest trial of its kind  Live ScienceFDA approves first gene therapy for inherited deafness, shown to restore hearing for children with rare condition  CNNFDA Approves First-Ever Gene Therapy to Restore Hearing  WSJMulticentre gene therapy for OTOF -related deafness followed up to 2.5 years  Nature'Impressive' trial results for experimental gene therapy for deafness | STAT  statnews.com

The treatment, the first of its kind, was approved by the Food and Drug Administration on Thursday. “Our baby was born deaf, and now he can hear,” said one parent.

The treatment, the first of its kind, was approved by the Food and Drug Administration on Thursday. “Our baby was born deaf, and now he can hear,” said one parent.

Regenerative therapy is any treatment therapy that improves tissue health or function. With that definition, we can include platelet-rich plasma (PRP), stem cells, and autologous conditioned serum (ACS). The post Regenerative Medicine: Promise, Hype, and What Actually Works appeared first on GEN - Genetic Engineering and Biotechnology News.

The Keck School of Medicine of USC and Keck Medicine of USC have launched collaborations with Tempus AI, Inc., a technology company at the forefront of applying AI to precision medicine, to integrate clinical care, clinical trials and research through a unified framework.

In a groundbreaking advancement in the treatment of mature T-cell and natural killer (NK) cell lymphomas, a newly published phase II clinical trial has demonstrated the promising therapeutic potential of allogeneic hematopoietic cell transplantation (allo-HCT). This study, recently unveiled in Nature Communications, heralds a new era that could substantially redefine the prognosis for patients afflicted […]

Doctors remain among the most trusted professionals in society — but AI is entering the consultation room, often without patients' knowledge.

The guest blog by Michael Happ of the Institute for Agriculture and Trade Policy (IATP) below provides an overview of what... The post USDA’s new Regenerative Agriculture Initiative: A step forward or greenwashing? appeared first on CalCAN - California Climate & Agriculture Network.

In the dynamic realm of genetic engineering, the dawn of retron-mediated recombineering represents a significant leap forward for the manipulation of bacterial genomes across diverse species. Traditionally, robust editing of Escherichia coli has paved the way for innovations in synthetic biology and microbial engineering, yet the extension of these precise editing tools beyond E. coli […]

Endpoints News was recognized with three 2026 Neal Awards for its coverage of the drug industry's relationship with the Trump administration, a three-part series on the future of CRISPR gene editing, and for its event ...

A startup that helps healthcare providers handle calls, texts and follow-ups with patients using AI has raised seed funding, Endpoints News learned exclusively. Gravity Rail handles the process of communicating with patients, from enrollment and ...

arXiv:2604.20488v1 Announce Type: new Abstract: Designing regulatory DNA elements with precise cell-type-specific activity is broadly relevant for cell engineering and gene therapy. Deep generative models can generate functional gene-regulatory elements, but existing methods struggle to achieve high specificity against undesired cell types while adhering to the genome's natural regulatory grammar. Here, we introduce DNA-CRAFT, a generative framework that integrates class-conditioned discrete diffusion with Monte Carlo tree search to design cell-type-specific and biologically faithful regulatory elements. We first train a discrete diffusion model on the ENCODE registry of 3.2 million candidate regulatory elements. Second, we condition the model to learn class-specific regulatory grammars of naturally occurring DNA sequences, including enhancers and promoters. Third, we employ conditional Monte Carlo tree guidance, an inference-time alignment algorithm designed to maximize the

arXiv:2604.20791v1 Announce Type: new Abstract: Large Language Models (LLMs) are increasingly deployed in healthcare, yet their communicative alignment with clinical standards remains insufficiently quantified. We conduct a multidimensional evaluation of general-purpose and domain-specialized LLMs across structured medical explanations and real-world physician-patient interactions, analyzing semantic fidelity, readability, and affective resonance. Baseline models amplify affective polarity relative to physicians (Very Negative: 43.14-45.10% vs. 37.25%) and, in larger architectures such as GPT-5 and Claude, produce substantially higher linguistic complexity (FKGL up to 16.91-17.60 vs. 11.47-12.50 in physician-authored responses). Empathy-oriented prompting reduces extreme negativity and lowers grade-level complexity (up to -6.87 FKGL points for GPT-5) but does not significantly increase semantic fidelity. Collaborative rewriting yields the strongest overall alignment. Rephrase

arXiv:2604.20166v1 Announce Type: new Abstract: Building trustworthy AI systems for mental health support is a shared priority across stakeholders from multiple disciplines. However, "trustworthy" remains loosely defined and inconsistently operationalized. AI research often focuses on technical criteria (e.g., robustness, explainability, and safety), while therapeutic practitioners emphasize therapeutic fidelity (e.g., appropriateness, empathy, and long-term user outcomes). To bridge the fragmented landscape, we propose a three-layer trust framework, covering human-oriented, AI-oriented, and interaction-oriented trust, integrating the viewpoints of key stakeholders (e.g., practitioners, researchers, regulators). Using this framework, we systematically review existing AI-driven research in mental health domain and examine evaluation practices for ``trustworthy'' ranging from automatic metrics to clinically validated approaches. We highlight critical gaps between what NLP currently

arXiv:2604.19998v1 Announce Type: new Abstract: Evaluating AI-generated reviews by verdict agreement is widely recognized as insufficient, yet current alternatives rarely audit which concerns a system identifies, how it prioritizes them, or whether those priorities align with the review rationale that shaped the final assessment. We propose concern alignment, a diagnostic framework that evaluates AI reviews at the concern level rather than only at the verdict level. The framework's core data structure is the match graph, a bipartite alignment between official and AI-generated concerns annotated with match type, severity, and post-rebuttal treatment. From this artifact we derive an evaluation ladder that moves from binary accuracy to concern detection, verdict-stratified behavior, decision-aware calibration, and rebuttal-aware decomposition. In a pilot study of four public AI review systems evaluated in six configurations, concern-level analysis suggests that detection alone does not

arXiv:2604.19914v1 Announce Type: new Abstract: Artificial intelligence systems are now deployed at scale across sectors, accompanied by a growing number of real-world incidents ranging from misinformation and cybercrime to autonomous-system failures. Databases of AI incidents index these events, but they cannot measure ``risk'' (i.e., a joint measure of likelihood and severity) without additional data regarding the prevalence of risk-associated systems and their incident reporting rates. As a result, policymakers, companies, and the general public lack a means to weigh the benefits of AI against their in-context risks. Inspired by public-health processes, which presume noisy and incomplete disease surveillance, we identify six phases of incident emergence. We demonstrate the framework through a detailed case study of autonomous vehicles, whose mandatory reporting requirements produces reliable incident-rate ground truth expressed in distance traveled. The case study shows that an

In a groundbreaking advancement that stands to transform the landscape of antimicrobial drug discovery, researchers at McMaster University have engineered a revolutionary generative artificial intelligence (AI) model named SyntheMol-RL. This model dramatically accelerates the often slow and prohibitively expensive process of identifying effective new antibiotics by navigating an expansive chemical universe that far surpasses traditional […]

  Many people spend months researching hair transplant clinics in Mumbai, comparing prices, scrolling through before-and-after photos, and reading reviews, only to realize after the procedure that they missed something important. A hair transplant is a surgical decision, and like any medical procedure, the outcome depends as much on preparation and informed choices as it ... Read more

Discovering he is getting old before his time, David Cox tries to lower his biological age by changing his diet in a helpful new book, The Age Code, says Graham Lawton

A new international study co-led by investigators from Mass General Brigham and the Eye & ENT Hospital of Fudan University shows that a gene therapy for a rare form of genetic deafness successfully restored hearing in most participants, with results lasting up to 2.5 years.

Heather Landi / Fierce Healthcare: Courier Health, which develops an AI-powered biopharma platform for managing the end-to-end patient experience, raised a $50M Series B led by Oak HC/FT  —  Oak HC/FT Norwest Venture Partners Patient experience Medication Adherence  —  Prescribing medications to patients is only one step …

Until now, there have been few therapeutic options for children with severely reduced heart pump function. Recently, surgical constriction of the pulmonary artery has been introduced as an innovative approach to deliberately "train" the heart. Researchers at the University Hospital Bonn (UKB) and the University of Bonn investigated the underlying biological mechanisms of this approach.

Chicken eggs are already used to harvest helpful proteins called antibodies to protect humans from viruses such as influenza. Now, a breakthrough at the University of Missouri could one day lead to chickens that produce other useful medical proteins in their eggs.

Multicentre gene therapy for OTOF -related deafness followed up to 2.5 years  NatureGene therapy for a rare type of deafness shows lasting results  NPR'Impressive' trial results for experimental gene therapy for deafness | STAT  statnews.comGene therapy improves hearing in 90% of patients with inherited deafness in largest trial of its kind  Live ScienceHearing restoration lasts years after gene therapy for inherited deafness, new trial results show  Medical Xpress

Multicentre gene therapy for OTOF -related deafness followed up to 2.5 years  NatureGene therapy for a rare type of deafness shows lasting results  NPR'Impressive' trial results for experimental gene therapy for deafness | STAT  statnews.comGene therapy improves hearing in 90% of patients with inherited deafness in largest trial of its kind  Live ScienceHearing restoration lasts years after gene therapy for inherited deafness, new trial results show  Medical Xpress

There is a large regeneration project of the city, in a modern and sustainable perspective, in the program Reggio Futura with Francesco Cannizzaro Mayor. An ... Read more L’article Starting again from urban regeneration, ideas for redemption from Reggio Futura est apparu en premier sur Odnako.

OpenAI is launching ChatGPT for Clinicians, a free tool for doctors, nurse practitioners, physician assistants and pharmacists. It’s the latest product the AI giant has launched within healthcare, after the company announced ...

A groundbreaking study published in the Journal of the American College of Cardiology (JACC) has brought to light crucial insights into how fitness during midlife significantly impacts not only lifespan but also the quality of health in later years. This comprehensive observational cohort study followed over 24,500 adults, revealing compelling evidence that higher cardiorespiratory fitness […]

Gene therapy for a rare type of deafness shows lasting results  NPRMulticentre gene therapy for OTOF -related deafness followed up to 2.5 years  Nature'Impressive' trial results for experimental gene therapy for deafness | STAT  statnews.comGene therapy improves hearing in 90% of patients with inherited deafness in largest trial of its kind  Live ScienceHearing restoration lasts years after gene therapy for inherited deafness, new trial results show  Medical Xpress

Gene therapy for a rare type of deafness shows lasting results  NPRMulticentre gene therapy for OTOF -related deafness followed up to 2.5 years  Nature'Impressive' trial results for experimental gene therapy for deafness | STAT  statnews.comGene therapy improves hearing in 90% of patients with inherited deafness in largest trial of its kind  Live ScienceHearing restoration lasts years after gene therapy for inherited deafness, new trial results show  Medical Xpress

In a groundbreaking advance for the treatment of hereditary deafness, researchers have reported promising long-term outcomes from a multicentre gene therapy trial targeting autosomal recessive deafness 9 (DFNB9), a severe form of congenital hearing loss caused by mutations in the OTOF gene. This study, published in Nature in 2026, highlights the sustained safety and efficacy […]

In a groundbreaking development that could reshape the therapeutic landscape of cardiovascular medicine, researchers have unveiled an innovative approach that harnesses the power of active mitochondria condensed within liquid–liquid phase-separated hydrogels to treat myocardial ischemia-reperfusion injury. This novel methodology represents a significant leap forward in addressing one of the most challenging complications following heart attacks, […]

Chicken eggs have long served as biological factories for producing antibodies, offering protection against viral threats such as influenza. In a groundbreaking development at the University of Missouri, researchers have now taken a significant leap forward by pioneering a method to engineer chickens capable of producing a broader range of medically valuable proteins within their […]

In a groundbreaking stride toward addressing the dire scarcity of therapeutic options for pediatric patients suffering from severe cardiac dysfunction, researchers at the University of Bonn have unveiled a novel understanding of how early surgical interventions may ignite the heart’s intrinsic regenerative prowess. This revelation stems from meticulous investigations into pulmonary artery constriction—a surgical technique […]

UCLA researchers have developed a lipid nanoparticle-based gene-editing approach capable of inserting an entire healthy gene into human

A new gene therapy tested in China has improved the hearing of 38 people who were born deaf due to mutations in a gene called OTOF.

A new international study co-led by investigators from Mass General Brigham and the Eye & ENT Hospital of Fudan University shows that a gene therapy for a rare form of genetic deafness successfully restored hearing in most participants, with results lasting up to 2.5 years. The results, the largest clinical trial of gene therapy for inherited hearing loss to date and the longest follow-up reported so far, are published in Nature. According to the authors, these latest findings reinforce earlier trials that show gene therapy can be used to treat some forms of inherited deafness, helping guide future research and care.

10x Science has raised a $4.8 million seed round to help pharmaceutical researchers understand complex molecules.

Solar prominences mystery solved by new simulations. Continue reading Researchers investigated how solar prominences form and their secret to longevity on Tech Explorist.

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arXiv:2604.18621v1 Announce Type: new Abstract: Quantum machine learning offers a promising new paradigm for computational biology by leveraging quantum mechanical principles to enhance cancer classification, biomarker discovery, and bioinformatics diagnostics. In this study, we apply QML to identify subtype specific biomarkers for lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC), the two predominant forms of non-small cell lung cancer. Our methodology involves a two-phase process: in Phase 1, differential expression analysis and methylation analysis between tumor and normal samples allows us to identify LUAD-specific and LUSC-specific genes, revealing potential prognostic biomarkers for cancer subtypes. Phase 2 focuses on developing a quantum classifier capable of distinguishing between LUAD and LUSC tumors, as well as between tumor and normal samples. This classifier not only enhances diagnostic precision but also demonstrates the quantum advantage in processing

arXiv:2505.20562v2 Announce Type: replace Abstract: Robotic surgery represents a major breakthrough in medical interventions, which has revolutionized surgical procedures. However, the high cost and limited accessibility of robotic surgery systems pose significant challenges for training purposes. This study addresses these issues by developing a cost-effective robotic laparoscopy training system that closely replicates advanced robotic surgery setups to ensure broad access for both on-site and remote users. Key innovations include the design of a low-cost robotic end-effector that effectively mimics high-end laparoscopic instruments. Additionally, a digital twin platform was established, facilitating detailed simulation, testing, and real-time monitoring, which enhances both system development and deployment. Furthermore, teleoperation control was optimized, leading to improved trajectory tracking while maintaining remote center of motion (RCM) constraint, with a RMSE of 5 {\mu}m and

arXiv:2604.18621v1 Announce Type: cross Abstract: Quantum machine learning offers a promising new paradigm for computational biology by leveraging quantum mechanical principles to enhance cancer classification, biomarker discovery, and bioinformatics diagnostics. In this study, we apply QML to identify subtype specific biomarkers for lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC), the two predominant forms of non-small cell lung cancer. Our methodology involves a two-phase process: in Phase 1, differential expression analysis and methylation analysis between tumor and normal samples allows us to identify LUAD-specific and LUSC-specific genes, revealing potential prognostic biomarkers for cancer subtypes. Phase 2 focuses on developing a quantum classifier capable of distinguishing between LUAD and LUSC tumors, as well as between tumor and normal samples. This classifier not only enhances diagnostic precision but also demonstrates the quantum advantage in processing