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Deep in the pharmacopoeia of Tibetan medicine lies a vast library of plants whose correct identification can mean the difference between a healing remedy and a useless or even harmful preparation. For centuries, that identification has depended on the trained eyes of practitioners, but a research team in Qinghai, China, now reports a machine learning […]

Cirrhosis can recur after liver transplantation, according to a study published online Sept. 3 in Portal Hypertension & Cirrhosis.

Most medical devices do not enter the market through rigorous safety testing but by being deemed similar enough to something already approved—the "predicate" device—through a mechanism known as the FDA's 510(k) pathway. But similar is not a synonym for safe. While the assumption may be that substantial equivalence is a reasonable stand-in for a safety review, some devices cleared with this method are still recalled, and the FDA spends valuable time reviewing devices the same way, regardless of how risky they appear on paper.

Sony's filings describe AI-generated diagnostic code for connected devices, while one application faced a final rejection before publication

Lithium-ion batteries quietly age every time they charge and discharge, and knowing exactly how much life remains inside a cell has become one of the most consequential measurement problems in modern energy technology. Electric vehicles, grid-scale storage systems and consumer electronics all depend on accurate estimates of the state of health, the measure that links […]

Inside every bacterial cell, RNA molecules carry far more information than their sequence of bases alone. After transcription, the four nitrogenous bases of RNA can be chemically altered by specialized enzymes, and these modifications influence how stable the molecules are, how efficiently they are translated into protein, and how the cell copes with stress. The […]

Every year, the world applies millions of tonnes of agrochemicals to crops and consumes billions of doses of pharmaceuticals, yet the safety story rarely ends when these compounds do their intended job. Once released into soil, water, and the human body, pesticides, herbicides, fungicides, and drugs are transformed by sunlight, microbes, plants, and metabolism into […]

The global spread of highly pathogenic avian influenza has exposed a persistent weakness in the world’s diagnostic arsenal: the tools that are most sensitive tend to be locked inside well-equipped laboratories, while the faster, simpler tests sacrifice the specificity needed to track emerging viral lineages. A research team led by Yujia Huang and Andrew Guo […]

Glioblastoma remains the most feared diagnosis in neuro-oncology. Despite surgery, radiotherapy, and chemotherapy, the tumor almost invariably returns, driven in part by its extraordinary cellular diversity and by a microenvironment that actively shelters malignant cells from treatment. Gene therapy delivered directly into the resection cavity offers one possible route forward, and adeno-associated virus (AAV) vectors […]

Treatment resistance remains one of the most stubborn obstacles in modern oncology, and a comprehensive new review published in the journal Molecular Cancer argues that a humble laboratory tool — the patient-derived organoid — may finally offer researchers a way to see the full architecture of that resistance in a single, living system. Writing as […]

Drug-induced seizures remain one of the most disruptive safety failures in modern pharmaceutical research, derailing promising molecules across therapy areas as diverse as the central nervous system, cardiovascular medicine, gastroenterology, respiratory disease and inflammation. Traditionally, seizurogenic risk only surfaces late, during rodent and non-rodent toxicology studies or, worse, once a compound has already entered clinical […]

State laws to combat disability-based discrimination in the organ transplant process aren't working, according to new research from The Ohio State University College of Medicine. The study, published in JAMA Internal Medicine, examines national policies designed to help all patients have a fair chance to receive an organ transplant. Despite 40 states passing laws prohibiting disability-based discrimination in the organ transplant process, people with intellectual and/or developmental disabilities (IDD) are still less likely to receive a kidney transplant than those without IDD.

4D microscopy gives AI a moving picture of the cell. Continue reading AI-built “Virtual Cells” could speed up drug discovery on Tech Explorist.

A sweeping new review argues that CRISPR-based gene editing could become one of the most consequential tools ever applied to African agriculture, but only if the continent can close persistent gaps in laboratory infrastructure, regulation, funding and seed delivery. The analysis, published in the journal Discover Agriculture, synthesizes nearly a decade of evidence on gene […]

Research from stem cell charity Anthony Nolan, published in Transplantation and Cellular Therapy, has revealed that 1 in 50 people studied has an "especially useful" gene variant that could make them a particularly desirable stem cell donor.

Nigerian surgeons remotely removed a cancer-affected kidney in West Africa’s first tele-robotic surgery Read Full Article at RT.com

When a failing heart is replaced through transplantation, or its workload is offloaded by a mechanical pump, physicians expect the body’s stress chemistry to calm down. The rationale seems straightforward: heart failure is driven in large part by a runaway neurohormonal response, and if the hemodynamic catastrophe is corrected, that response should switch off. A […]

Few technologies have unsettled the conventions of pharmaceutical research quite like induced pluripotent stem cells, or iPSCs. A sweeping review published in Discover Biotechnology examines how, between 2020 and 2024, these reprogrammed human cells have moved from laboratory curiosity to a central engine of novel drug development, offering researchers something that has long been out […]

A new government program that will push the boundaries of AI in medicine could transform how the US cares for patients with heart failure and eventually other chronic diseases. But that’s only if the public’s ...

Senescent cells accumulate with age, likely largely because the aging of the immune system slows down the clearance of senescent cells, but the relative importance of different contributions to the growing burden of senescence in aging tissues is an area of ongoing discussion. Senescent cells secrete inflammatory signals that are disruptive to tissue structure and function when sustained over the long term. Separately, cells throughout the body accumulate mutations over the course of aging. Much of this has little to no effect, occurring in cells with few replications remaining, or in genes not used by the cell. However, a growing burden of mutation in stem cell populations spreads slowly into the tissues they support via the daughter somatic cells generated to replace those cells lost […]

arXiv:2609.24842v1 Announce Type: cross Abstract: Proteins can possess numerous mutations relative to their wild-type amino acid sequences with minimal impact to their structure and function. However, in other cases, even a single amino acid mutation relative to the wild-type sequence can lead to a large change in structure or even a disease phenotype. While the accuracy of wild-type protein structure prediction has improved significantly in recent years, it remains difficult to accurately predict the structure of mutant proteins. Here, we characterize the local mutation-induced structural changes in proteins for a dataset of wildtype and the corresponding single-amino acid mutant x-ray crystal structures from the Protein Data Bank (PDB). We find that mutation-induced structural changes in these proteins are localized at the site of the mutation, decaying rapidly with increasing spatial distance from the mutation site. In addition, we evaluate how well AlphaFold3 can recapitulate the

arXiv:2609.24842v1 Announce Type: new Abstract: Proteins can possess numerous mutations relative to their wild-type amino acid sequences with minimal impact to their structure and function. However, in other cases, even a single amino acid mutation relative to the wild-type sequence can lead to a large change in structure or even a disease phenotype. While the accuracy of wild-type protein structure prediction has improved significantly in recent years, it remains difficult to accurately predict the structure of mutant proteins. Here, we characterize the local mutation-induced structural changes in proteins for a dataset of wildtype and the corresponding single-amino acid mutant x-ray crystal structures from the Protein Data Bank (PDB). We find that mutation-induced structural changes in these proteins are localized at the site of the mutation, decaying rapidly with increasing spatial distance from the mutation site. In addition, we evaluate how well AlphaFold3 can recapitulate the

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Stem cell transplants helped regenerate stroke-damaged brain tissue in mice, producing new neurons and restoring lost motor function. The treatment also improved blood vessels, inflammation, and the blood-brain barrier, raising hopes that a similar approach could eventually help repair the human brain after stroke.

A noncontiguous code for RNA-guided DNA recognition at the origin of CRISPR-Cas  Science | AAASDiscovery of CRISPR's long lost ancestor may expand gene-editing toolkit  Phys.orgThe Next Gene-Editing Technology May Also Be the Oldest  The New York Times

A noncontiguous code for RNA-guided DNA recognition at the origin of CRISPR-Cas  Science | AAASDiscovery of CRISPR's long lost ancestor may expand gene-editing toolkit  Phys.orgThe Next Gene-Editing Technology May Also Be the Oldest  The New York Times

Ученые ЦНИИ Эпидемиологии Роспотребнадзора разработали тест-систему, которая позволяет выявлять ген устойчивости бактерий к метициллину. Новинку создали на основе технологии CRISPR/Cas.

Marine scientists have been amazed to discover an endangered sea cucumber can live for decades, with some animals living more than 100 years, in a first-of-its-kind genetic mark-recapture study. Australian Institute of Marine Science (AIMS) Senior Principal Research Scientist Dr. Sven Uthicke said the findings suggested black teatfish sea cucumber populations recover much more slowly than previously thought and that this had implications for commercial fishery catch limits.

Artificial intelligence is rapidly transforming how one of medicine’s most information-rich cancer scans is read, and a new comprehensive review argues that lymphoma may be the field where the change hits hardest. Published in Holistic Integrative Oncology, the review systematically synthesized 53 original studies, selected from an initial pool of more than 1,000 papers under […]

For more than a decade, cellular senescence has been one of the most compelling stories in aging research. Senescent cells—viable but permanently arrested cells that secrete inflammatory molecules—accumulate in tissues over time, and landmark animal studies showed that chemically clearing them can extend lifespan and ease a remarkable range of age-related diseases. Now, a comprehensive […]

Artificial intelligence is transforming medicine at breathtaking speed, diagnosing heart disease from electrocardiograms, flagging sepsis hours before clinicians suspect it, and drafting clinical notes in seconds. Yet a new commentary in the Journal of Medical Systems argues that the hardest problems facing clinical AI are not computational at all. They are philosophical. Antonis A. Armoundas […]

Researchers identified genes that enable the regeneration of dopamine-producing neurons in planarians. This provides a roadmap for investigating whether similar pathways can be activated in humans and potentially leveraged to treat traumatic brain injuries and neurodegenerative diseases. The post Genes Involved in Flatworm Brain Regeneration Identified appeared first on GEN - Genetic Engineering and Biotechnology News.

Beacon Therapeutics said on Monday its experimental gene therapy improved the ability to read ⁠in low-light conditions in a late-stage trial on people with a form of...

RamanOmics decodes the spatial vibrational–molecular architecture of senescence in aging and repair  NatureUnmasking “zombie cells” in aging tissue with an AI-powered barcode  MIT NewsHarvard Medical School uses RamanOmics to barcode senescent ‘zombie cells’ and measure biological age  dongascience.comThe chemical fingerprint of cellular senescence  Nature

RamanOmics decodes the spatial vibrational–molecular architecture of senescence in aging and repair  NatureUnmasking “zombie cells” in aging tissue with an AI-powered barcode  MIT NewsHarvard Medical School uses RamanOmics to barcode senescent ‘zombie cells’ and measure biological age  dongascience.comThe chemical fingerprint of cellular senescence  Nature

Radicals, atoms or molecules that readily react with other substances to form new bonds, are useful tools for building complex substances such as pharmaceuticals. But even when a radical is generated efficiently, the reaction cannot continue unless the catalyst returns to its original state.

Companies have invested heavily in workplace mental health, yet many employees and managers are still struggling. The next evolution is helping people build the capacity to perform, adapt and grow as the demands of work continue to change.

Researchers led by Assistant Professor Lynn Yap of the Lee Kong Chian School of Medicine at Nanyang Technological University, Singapore, have uncovered new insights into how unspecialized cells, also known as stem cells, develop and mature into heart muscle cells. The findings could pave the way for new treatments for heart disease.

Sanfilippo syndrome type A (MPS IIIA) is a rare, fatal lysosomal storage disease that primarily affects the central nervous system and is marked by rapid neurodegeneration beginning in early childhood. The post Andelyn Curator Biomanufacturing Platform Supports Fayuvi Gene Therapy Approval appeared first on GEN - Genetic Engineering and Biotechnology News.

Bone marrow transplants offer an unexpected way for diseased cells in the heart and brain to get replacement parts, a Stanford Medicine-led study has shown. The finding offers hope for the first effective treatment of mitochondrial disorders, a group of genetic diseases in which cells' motors, called mitochondria, are dysfunctional.

The collaboration combines Biographica’s computational platform for identifying high-value gene targets and Hudson River’s expertise in gene-editing. The post ‘Bring us your difficult trait problems’: Biographica, Hudson River partner on crop genome editing appeared first on AgFunderNews.

Brock E.W. Turner / Axios: NYC-based Corridor, which uses AI to offer health benefits for small businesses, raised a $16M seed led by Bain Capital Ventures, following a $9M pre-seed  —  Corridor, an AI-native health benefits broker, raised $16 million in seed funding led by Bain Capital Ventures, CEO Nikhil Aggarwal tells Axios Pro exclusively.

Ученые ЦНИИ Эпидемиологии Роспотребнадзора разработали набор реагентов для выявления ДНК mecА (ген устойчивости к метициллину) методом ПЦР с детекцией CRISPR/Cas AmpliSens® mecА CRISPR.

Scroll through social media and you will soon encounter advice about living longer, from fasting plans and supplements to elaborate daily routines. Yet reaching an advanced age tells us little about how healthy or independent those later years will be.

Some of the earliest opportunities to prevent a mental health crisis may come outside of a therapist's office. They may happen at a divorce attorney's desk, in a bankruptcy hearing or at a self-storage counter—anywhere people may be navigating a major life disruption.

The AI tool, called "EndoFusion," is a recent development from IMAGENDOÒ, an ongoing collaborative study led by Adelaide University researchers. In this latest study, researchers found the framework could accurately identify two major indicators of advanced endometriosis in pelvic scans, producing results in just 18 milliseconds.

Exclusive: Research and invention agency hopes to harness ‘powers of biotechnology’ for purpose of conservation Vaccines for ash trees, skin treatments for newts and gene-edited swallowtail butterflies are among 14 tax-funded projects from the UK’s “invention agency” aiming to accelerate nature’s ability to adapt to the climate crisis. The £54m accelerated adaptation programme from the UK’s Advanced Research and Invention Agency (Aria) – a public body that funds high-risk, high-reward tech projects – aims to investigate applications of biotechnology that can speed up wild species’ evolution and help them to adapt to new threats such as global warming and disease. Continue reading...

The human brain is terrible at healing itself from injury or disease. But some animals can harness their own cellular abilities not only to repair injuries but also to regrow their brains entirely. Researchers from the University of Georgia have pinpointed several of the genes that make brain regeneration possible in one type of flatworm.

Beacon Therapeutics has succeeded in a genetic eye disease where large drugmakers including Johnson & Johnson and Biogen have failed. On Monday, Beacon said its gene therapy for X-linked retinitis pigmentosa (XLRP) passed a Phase ...

Новые законы, разделяющие традиционные ГМО и продукты точечного редактирования генома (NGT/GE), требуют надежных методов контроля на таможне и рынке. Без таких решений, как RiSpy, их реализация становится крайне сложной. Международный...

It’s been a while since I talked with Owen Tripp, CEO of Included Health. They’ve now introduced Dot their AI companion which had a big upgrade last week. We talked a littleContinue reading...

arXiv:2609.21038v1 Announce Type: cross Abstract: Induced pluripotent stem cell (iPSC) culture increasingly relies on segmentation foundation models, yet deployment on laboratory CPUs and edge hardware requires compression schemes that are both efficient and auditable. We present a deployment-oriented evaluation of compressed Cellpose-SAM using a pre-specified retention criterion: the 95% cluster-bootstrap interval of mean change from FP32 must remain above a fixed -0.02 margin for every imaging modality. On a stratified 176-field panel spanning BBBC038 nuclei, BBBC039 U2OS fluorescence, and NIST iPSC images across density regimes, weight-only W8A16 preserves instance F1 across all modalities. A sensitivity-guided mixed W4/W8 scheme, using four INT8 exceptions, achieves a 6.76x reduction in weight storage with no observed catastrophic failures (0/176 fields), matching W8A16 at this sample size. In contrast, ternary weight-only quantization achieves 12.08x compression but fails

arXiv:2609.21867v1 Announce Type: cross Abstract: Brane tilings are bipartite graphs on a 2-torus that encode the Lagrangians of 4d N=1 supersymmetric gauge theories arising on D3-branes probing toric Calabi-Yau 3-folds. Among these bipartite graphs, only those that satisfy geometric consistency conditions correspond to well-behaved quantum field theories. We train a convolutional neural network (CNN) to distinguish geometrically consistent from inconsistent brane tilings directly from their Kasteleyn matrices. We study a family of 4d N=1 theories obtained by adding diagonal edges to the hexagonal faces of the brane tiling for the abelian orbifold C^3/Z_3 x Z_3, and find that the CNN identifies geometric inconsistency with high accuracy. For inconsistent brane tilings that can be rendered consistent by Higgsing a single bifundamental chiral field, we show that gradient-based saliency analysis can be used to localize the responsible chiral fields with accuracy well above a matched

arXiv:2609.21038v1 Announce Type: new Abstract: Induced pluripotent stem cell (iPSC) culture increasingly relies on segmentation foundation models, yet deployment on laboratory CPUs and edge hardware requires compression schemes that are both efficient and auditable. We present a deployment-oriented evaluation of compressed Cellpose-SAM using a pre-specified retention criterion: the 95% cluster-bootstrap interval of mean change from FP32 must remain above a fixed -0.02 margin for every imaging modality. On a stratified 176-field panel spanning BBBC038 nuclei, BBBC039 U2OS fluorescence, and NIST iPSC images across density regimes, weight-only W8A16 preserves instance F1 across all modalities. A sensitivity-guided mixed W4/W8 scheme, using four INT8 exceptions, achieves a 6.76x reduction in weight storage with no observed catastrophic failures (0/176 fields), matching W8A16 at this sample size. In contrast, ternary weight-only quantization achieves 12.08x compression but fails

arXiv:2609.21038v1 Announce Type: cross Abstract: Induced pluripotent stem cell (iPSC) culture increasingly relies on segmentation foundation models, yet deployment on laboratory CPUs and edge hardware requires compression schemes that are both efficient and auditable. We present a deployment-oriented evaluation of compressed Cellpose-SAM using a pre-specified retention criterion: the 95% cluster-bootstrap interval of mean change from FP32 must remain above a fixed -0.02 margin for every imaging modality. On a stratified 176-field panel spanning BBBC038 nuclei, BBBC039 U2OS fluorescence, and NIST iPSC images across density regimes, weight-only W8A16 preserves instance F1 across all modalities. A sensitivity-guided mixed W4/W8 scheme, using four INT8 exceptions, achieves a 6.76x reduction in weight storage with no observed catastrophic failures (0/176 fields), matching W8A16 at this sample size. In contrast, ternary weight-only quantization achieves 12.08x compression but fails

arXiv:2609.21369v1 Announce Type: new Abstract: This paper presents a comprehensive framework for robot manipulation failure analysis that includes binary failure detection, failure categorization, explanation generation, and the additional capability of failure onset localization, which aims to identify the earliest moment at which a robot execution deviates from a valid task-completion trajectory and is ultimately followed by task failure. To address these tasks, we propose ProTracer, a training-free framework that leverages existing Vision-Language Models (VLMs) together with proprioceptive signals for failure analysis. Our method uses proprioceptive dynamics to identify temporally informative action boundaries and converts richer robot-state signals into structured natural-language descriptions that can be jointly analyzed together with visual observations by the VLM. This design combines the temporal precision of proprioceptive signals with the multimodal reasoning capabilities

A team of researchers in China has reported the discovery and engineering of an unusually small CRISPR protein that can shut genes down without cutting DNA, and they have used it to build a compact epigenetic silencing system that fits inside a single adeno-associated virus vector. In a study published in Nature Structural & Molecular […]

Every year, millions of people worldwide undergo surgery to repair broken, diseased, or surgically resected bone, and a large share of those operations still depends on materials that merely fill the gap rather than help the body rebuild itself. A new review published in the journal Advanced Composites and Hybrid Materials argues that one ceramic, […]

Artificial intelligence has quietly become one of the most powerful forces reshaping how humanity fights cancer, and for the first time, researchers have mapped the entire landscape of this revolution. A sweeping bibliometric analysis published in Clinical Cancer Bulletin has examined 15,554 publications spanning 2011 to 2025, offering the most comprehensive picture yet of how […]

Every year, plant breeders and biotechnologists around the world rely on a seemingly magical property of plant cells: their ability to regenerate an entire organism from a small piece of tissue. Yet behind the scenes of micropropagation laboratories and gene-editing pipelines lies a stubborn problem. Many plant genotypes simply refuse to regenerate. Explants form a […]

Artificial intelligence is quietly rewriting the rules of pharmaceutical science, and a new comprehensive review argues that the transformation is only beginning. The study, published in the journal Quantum Machine Intelligence, systematically synthesizes the fast-moving landscape of AI-driven drug discovery and personalized medicine, bringing together three previously separate research streams: classical machine learning, generative models, […]

For decades, the design of nanoparticle drug delivery systems has been an exercise in patient, expensive trial and error. Formulation scientists would mix lipids, polymers and drug payloads in one combination after another, measure what came out, and iterate slowly toward something that worked. A new review published in Nature Reviews Bioengineering argues that this […]

Patients who undergo allogeneic hematopoietic stem cell transplantation, one of the most demanding procedures in modern medicine, may face a largely hidden nutritional hazard long after their infusion day. A new retrospective study from the Medical University of Warsaw, published in Annals of Hematology, reports that nearly half of transplant recipients develop vitamin B12 deficiency […]

Researchers have successfully conducted the first clinical trial using activated regulatory T cells (ATregs, Actileucel)—derived from white blood cells of healthy blood donors. This novel cell therapy aims to prevent graft-versus-host disease (GvHD) following an allogeneic stem cell transplant. The Phase I/II study has yielded extremely encouraging results: ATregs can be produced within 24 hours and injected immediately afterward; administration is safe and well-tolerated by patients—a significant step toward a widely available cell therapy. The research is published in Transplantation and Cellular Therapy.

Researchers have uncovered a previously unknown gene causing resistance to a leading blood cancer drug and several genes that accelerate lymphoma growth by using a powerful new CRISPR activation library.

Mitochondria—tiny structures that convert nutrients into energy—are often depicted as discrete kidney bean-shaped objects. But in reality, they form a dynamic, interconnected network throughout the entire cell, rapidly splitting and fusing as they're transported to where energy is needed most.

Sarah Neville / Financial Times: Clinicians raise concerns over medical AI adoption beyond diagnostics and imaging, citing limited clinical and performance data on its broader effectiveness  —  The technology's advances have not yet translated into big improvements in real-life care.  Kayla Secrest was a newly fledged doctor beginning …

Новый выпуск SciNat, скорее всего, порадует любителей нейробиологии, так как последние недели оказались очень насыщенными на перспективные и прорывные работы в этой сфере. Также в нашем дайджесте вы познакомитесь с самыми разными исследованиями: от молекулярных механизмов сборки вирусоподобных частиц до полной карты нервной системы мухи.

A new study reveals insights into populations of neurons affected by Huntington’s disease, schizophrenia, addiction, and other disorders.

The system, designed by Stanford researchers, identified which drugs are more likely to succeed in trials and even proposed a cancer treatment a major drugmaker later landed on too. The post Virtual Biotech Company Puts 37,000 AI Agents to Work on Drug Discovery appeared first on SingularityHub.

Maria Armental / Wall Street Journal: Angle Health, which wants to use AI to expedite healthcare benefits for small businesses, raised $600M led by Vitruvian Partners at a $2.7B valuation  —  Founded by two ex-Palantir engineers, the startup aims to bring AI-platform power to small-business healthcare benefits

Doctor-CEO Oliver Kharraz explained why healthcare keeps humbling corporate giants.

Longevity has no shortage of products, science, capital or consumer interest. The bottleneck is translation: getting promising science validated, understood by clinicians, implemented responsibly and ultimately to patients.

Researchers have uncovered a previously unknown gene that causes resistance to a leading blood cancer drug, as well as several genes that accelerate lymphoma growth, using a powerful new CRISPR activation library.

Every time a person sees a doctor, the visit produces two kinds of records. There are the tidy checkbox fields: the billing codes, the lab values, the prescription entries. And there is the note the clinician actually writes, describing what the patient said, how they are coping, what side effects they mentioned and why a medication was changed.

CRISPR may be a powerful technology for gene editing, but the system existed in bacteria long before scientists began using it. For billions of years, CRISPR has acted as a natural immune system in bacteria and other microbes, helping defend them against invading viruses. But now, two new studies, published in Science, describe a similar RNA-guided system that originated in the viruses themselves and appears to be a precursor to CRISPR.

The FDA approved Fayuvi, the first gene therapy for Sanfilippo syndrome type A. What families should know about access, cost and safety checks.

This cartridge-playing Game Boy clone is smaller and cheaper than Analogue’s Pocket  The VergeFunnyPlaying's New Mini GAME BOY That Plays Cartridges Is Now Up For Sale  Retro DodoThis cheap handheld can emulate games, but also plays your physical GBA cartridges  Android AuthoritySome characteristics of the FPGB Mini portable console - a mini version of the Game Boy from FunnyPlaying - revealed  ixbt.gamesThe first batch of FPGB Mini portable consoles sold out in 10 minutes by retrogamers  ixbt.games

This cartridge-playing Game Boy clone is smaller and cheaper than Analogue’s Pocket  The VergeFunnyPlaying's New Mini GAME BOY That Plays Cartridges Is Now Up For Sale  Retro DodoThis cheap handheld can emulate games, but also plays your physical GBA cartridges  Android AuthoritySome characteristics of the FPGB Mini portable console - a mini version of the Game Boy from FunnyPlaying - revealed  ixbt.gamesThe first batch of FPGB Mini portable consoles sold out in 10 minutes by retrogamers  ixbt.games

Ученые обнаружили в вирусах древнюю систему редактирования генов, которая, вероятно, появилась раньше CRISPR. Она получила название VIPR и использует необычный способ распознавания ДНК: не считывает последовательность непрерывно, а пропускает каждую третью букву генетического кода. Такая особенность позволяет системе сохранять способность находить цель даже после мутаций, а небольшой размер VIPR может упростить ее доставку в клетки.

FunnyPlaying, a Chinese company known for its Game Boy and GBA upgrade kits, has announced a new handheld that plays original Nintendo cartridges and ROMs. The FPGB Mini's cartridge support is limited to the Game Boy and Game Boy Color so it isn't as capable as the Analogue Pocket that's also compatible with the GBA and Sega Game Gear. What still makes the FPGB Mini a tempting alternative is its extremely pocketable design resulting in a handheld only slightly wider than a Game Boy cartridge, and its cheaper price. The FPGB Mini allows for multiplayer and trading over a USB-C cable. | Image: FunnyPlaying" data-portal-copyright="Image: FunnyPlaying"> Following recent price hikes the Analogue Pocket is now $239.99 while the FPGB Mini is currently discounted from $89.99 to $69. … Read the full story at The Verge.

Alibaba Group Holding’s research arm, Damo Academy, has open-sourced an artificial intelligence model capable of identifying nearly 150 abdominal conditions – including cancers – by reading computed tomography (CT) scans, marking the latest step in the firm’s growing medical AI efforts. The vision-language model, called Damo Radar, was designed to analyse contrast-enhanced CT scans covering 18 abdominal organs and identify a broad range of diseases and other abnormalities, such as malignant...

A Nature study found semaglutide raised median lifespan in aged female mice by about 12 percent. Researchers say the finding does not apply to people.

SAN FRANCISCO — Anthropic has quietly set up a laboratory to do physical biology work as it pushes its artificial-intelligence ambitions into the world of drug science. At a time when fears of AI are gripping the public, the startup has built a wet lab, or place for physical experiments, in the San Francisco Bay Area, two people familiar with the matter said. Anthropic has said it wants to unlock treatments for rare diseases, and its biology work has gone beyond "in silico" or computer evaluations. In a Reuters interview on Tuesday, Anthropic's head of life sciences, Eric Kauderer-Abrams, confirmed the startup's wet lab. "We believe that to do biology, the final test is still and will be for a while in real lab work," he said. "We absolutely are doing that today, and I would describe our approach as being typical of what you would see in most biotech companies, where there's some amount of that that we're doing in our own facilities and some amount of that that we're working with

Reception is where most practices leak revenue. Calls go unanswered at lunch, after hours and during every appointment

Thousands of women in England with an incurable form of breast cancer will gain access a life extending drug on the NHS after successful negotiations over its cost.NHS England will make trastuzumab deruxtecan (Enhertu, made by Daiichi Sankyo and Astra Zeneca) available to around 1000 women with HER2 low advanced or metastatic breast cancer whose disease has progressed after treatment.This came after an updated recommendation from the National Institute for Health and Care Excellence (NICE) that has been hailed as “momentous” by campaigners, who previously criticised the decision not to recommend the treatment.1The deal follows changes to NHS rules determining which drugs provide value for money that were made as part of the UK-US drug pricing deal.2HER2 low is a subgroup of breast cancer previously considered HER2 negative. People with HER2 low metastatic or unresectable breast cancer have cancer cells with low amounts of HER2 protein.Clinical trial evidence shows that...

Once the music industry’s biggest headache, Napster’s next act is bringing AI to the classroom.

How a team of AIs discovered a promising lung-cancer drug  NatureVirtual biotech company puts thousands of AI scientist agents to work on drug discovery  Phys.orgA.I. Agents as ‘Co-Scientists’? This Lab Says They Could Speed Drug Research.  The New York TimesAI Pharmaceutical Company with 37,000 Researchers Emerges  조선일보AI Agents Collaborate to Streamline Drug Discovery  Inside Precision Medicine

How a team of AIs discovered a promising lung-cancer drug  NatureVirtual biotech company puts thousands of AI scientist agents to work on drug discovery  Phys.orgA.I. Agents as ‘Co-Scientists’? This Lab Says They Could Speed Drug Research.  The New York TimesAI Pharmaceutical Company with 37,000 Researchers Emerges  조선일보AI Agents Collaborate to Streamline Drug Discovery  Inside Precision Medicine

GenCelix (Founder & CEO Minji Kang), a company specializing in cell technology and manufacturing, announced that it signed a trilateral memorandum of understanding (MOU) with DKMG (President Hyungsuk Kim) and Japan-based KOHJIN BIO (Founder & Chairman Takahito Nakamura) on Sept. 7, at Hilton Garden

Researchers created xenocortical mice by transplanting human cortical organoids into animals genetically depleted of much of their native cortex, allowing the human tissue to occupy most of the available cortical space and form anatomical connections throughout the host nervous system. The grafts developed diverse cortical cell types, including L5-ET and VEN-like neurons, generated organized neural activity, and produced measurable cellular and behavioral responses to hypoxic injury.

Danaher companies Integrated DNA Technologies (IDT), a global leader in genomics, and Aldevron, a premier manufacturing partner for DNA, RNA, and protein, today announced the launch of research grade S.p. Cas9 mRNA in wild type and SpyFi™ high-fidelity formats.

arXiv:2609.20499v1 Announce Type: new Abstract: The paper presents a numerical approach for the end-effector trajectory smoothing of a parallel robot designed for minimally invasive pancreatic surgery. The approach is tailored for real-time master-slave control architecture and uses a 3D space mouse for command input for velocity control. The trajectory smoothing is achieved by generating S-curves in the end-effector velocity fields, thus controlling the accelerations, which in turn reduces tissue trauma in the minimally invasive procedures. Real-time control is enabled by segmenting the S-curves based on the command inputs from the 3D space mouse. A special case is considered where the acceleration time is constant for all command inputs. Numeric results demonstrate stable transitions (without abrupt changes) in both the end-effector parameter space and in the active joints parameters, thereby validating the proposed approach. Further work aims to test the approach on an experimental

arXiv:2609.20275v1 Announce Type: new Abstract: Hybrid brain-computer interface (BCI) systems that integrate electroencephalography (EEG) and electromyography (EMG) signals have shown significant potential in improving the reliability of motor imagery (MI) classification, particularly in neuro-rehabilitation applications. However, identifying informative EEG-EMG channel pairs that effectively capture corticomuscular interactions remains a challenging problem, as existing approaches typically rely on manually predefined channel combinations that may not generalise across subjects. In this work, a data-driven EEG-EMG pair selection framework is proposed, in which channel pair selection is formulated as a constrained bi-objective optimisation problem. The proposed method jointly maximises the spatial relevance of EEG channels with respect to motor cortex regions and the corticomuscular coupling strength between EEG and EMG signals, and is solved using the NSGA-II to automatically