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Studies presented at the AMP 2026 Annual Meeting demonstrated artificial intelligence applications for cancer classification, clinical reporting, specimen triage, and genomic prediction.

A clinical study of 976 patients and experimental models demonstrate that donor-derived unlicensed natural killer cells accelerate hematopoietic recovery and improve survival after allogeneic stem cell transplantation.

Researchers at the National University of Singapore (NUS) have developed a catalyst-regeneration strategy that could make hydrogen production from ammonia more efficient and reliable. By tackling a major problem that causes catalysts to lose their effectiveness over time, the team sustained hydrogen production for over 2,000 hours in laboratory tests.

A comprehensive review synthesizes how enzymatic control of messenger RNA poly(A) tail lengths dictates post-transcriptional gene expression in mammalian stem cells and early embryogenesis.

Wildfires bring to mind a blazing sea of flames. But what happens to the smoke? Anyone observing a wildfire from a safe distance notices mainly the enormous clouds that tower above the fire. These rise several kilometers and then embark on journeys that can extend across continents and oceans. Pollutants from wildfires in Canada can still be detected, for example, at the Jungfraujoch in the Swiss Alps.

A fourteen-year panel analysis of thirty-eight OECD countries found no robust evidence that government effectiveness moderates the association between public healthcare expenditure and life expectancy.

A study of public hospital procurement in China shows medical AI diagnostic hardware converged geographically while concentrating heavily in tertiary facilities.

Researchers mapped direct transcriptional targets of the pluripotency factor Oct4 in mouse embryonic stem cells by combining auxin-inducible degron degradation with nascent RNA sequencing.

Fat that builds up in the pancreas is one of the lesser-known risk factors for diabetes and metabolic syndrome, but it turns out it can be targeted directly through what's on the plate.

This week, Google launched Gemini for healthcare. Google has long been a fixture in health, helping hospitals store data in Google Cloud, selling a wellness device through Fitbit and spinning out startups such as Verily ...

A sizable number of humans have received first generation stem cell therapies, with considerable variation in protocols and sources of cells. Only a small fraction of these patients and treatments resulted in data that was robustly recorded and made available to the rest of the world, as only a small fraction of those patients were participants in clinical trials. Stem cell therapies (and, given more time, likely exosome therapies as well) have an entirely justified reputation as being unreliable in outcome. The available evidence suggests a fairly reliable reduction in chronic inflammation for a period of months, but whether or not a patient exhibits improved function in tissues, and to what degree, is a roll of the dice. One of the reasons why the world […]

Tiny doses of GLP-1s are being marketed as antiaging drugs, but what evidence is there?

Paris-based Orakl Oncology has raised a $34M Series A co-led by Norrsken VC and Singular. It grows copies of patients’ tumours in the lab, tests drugs on them and uses AI to predict trial results. It will expand into lung and gastric cancer. Paris-based Orakl Oncology has raised a $34M Series A to predict how […] This story continues at The Next Web

Germany’s former health minister Karl Lauterbach has said that curing cancer, Alzheimer’s and mental illness within ten years is impossible. He was answering Dario Amodei, whose company’s IPO roadshow video says those diseases will be “relics of the past” within a decade. Doctors and a biotech executive have pushed back too, Business Insider reported on […] This story continues at The Next Web

A comprehensive review examines how evolving medical bioadhesives bridge chemical mechanisms and surgical requirements while navigating key clinical translation barriers.

A single-cell RNA sequencing study reveals that CDKN2A-associated senescence and Pfirrmann-graded degeneration in human nucleus pulposus tissue show heterogeneous, non-concordant cellular patterns.

Google says it’s working on a fix – meantime, users have found workarounds.

Mitochondria can become compromised in a number of medical conditions. What if they could be replaced like batteries?

A gelatin-assisted CRISPR/Cas12a assay achieves rapid and sensitive detection of Listeria monocytogenes in food safety testing.

Researchers at Arizona State University, U.S., have found that a high-fat diet leaves lasting changes in intestinal stem cells, potentially increasing the risk of tumor development.

Study identifies that MARK2 promotes stem cell characteristics and drug resistance in hepatocellular carcinoma through Wnt and PI3K/AKT signaling.

CHICAGO — A gene-editing therapy targeting hepatic ANGPTL3 lowered triglycerides in patients with severe hypertriglyceridemia, according to results of a phase 1b study presented at the American Heart Association Scientific Sessions.Ashish Sarraju, MD, cardiologist in the section of preventive cardiology in the Tomsich Family Department of Cardiovascular Medicine of The Sydell and Arnold Miller Family Heart, Vascular & Thoracic Institute, Cleveland Clinic, presented the results of the study of 10 patients (median age, 56.5 years; 60% men; median triglycerides, 1,067.7 mg/dL) who received

A multicenter retrospective cohort study across 34 Chinese hospitals found that biosimilar insulin aspart provided glycemic control and safety comparable to the originator product in patients with type 1 diabetes.

Raymond, 66, lived in constant fear of becoming a burden to his family in recent years as his lung disease, diagnosed 16 years ago, worsened, and he needed an organ transplant to survive. The pulmonary fibrosis patient said on Thursday that he had waited to receive a lung transplant for more than two years after being placed on the waiting list in 2023. His brother, who suffered from the same condition, died three years after being diagnosed. Pulmonary fibrosis is one of more than 200 lung...

A comprehensive review of 36 contemporary studies examines artificial intelligence models across thyroid cancer diagnosis, risk stratification, and treatment planning while emphasizing the critical need for prospective clinical validation.

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. What to know about this year’s UN climate talks Thousands of delegates, lobbyists, and journalists have gathered in Antalya, Turkey, for COP31, the annual UN climate talks. But this year’s negotiations…

Researchers have identified TRPM7 as a critical driver of chondrocyte senescence and osteoarthritis progression through a PDK4-mediated organelle tethering and cGAS-STING signaling pathway.

Health insurers are using AI to deny care. You can use it to fight back.

According to German Gref, the bank’s key objective for 2027-2029 is to position itself as a driver of the new economy

Transcriptome analysis of Rosa hybrida somatic embryos revealed distinct starch aerobic decomposition gene expression profiles between organogenesis-like regeneration and seed-like germination.

Researchers found that PIWIL2 represses the pluripotency factor SOX2 in the male mouse germline through embryonic DNA methylation alongside post-transcriptional controls by DMRT1 and DAZL.

A meeting report from the 5th China Annual Congress on Cell and Gene Therapy highlights clinical progress in immune and gene therapies alongside ongoing challenges in manufacturing, regulation, and long-term safety evaluation.

A controlled experimental study reveals that healthcare users place greater trust in generative AI when it explains established diagnoses rather than delivering standalone medical assessments.

A scientific review details how anti-CRISPR technologies serve as controllable off-switches to enhance precision and safety across therapeutic, agricultural, and gene-drive applications.

A dual-layered framework pairing discrete wavelet watermarking with Ethereum-based registry tracking achieves deterministic byte-level tamper detection across clinical radiographs while revealing extraction limitations under additive singular value decomposition.

Senescent cells are constantly created throughout life, but accumulate in aged tissues as a result of a growing age-related failure of the immune system to promptly clear these cells. Evidence suggests that one contribution to this lack of clearance is that senescent cells in aged tissues increasingly employ immune evasion markers. The research community has already mapped a range of immune evasion markers in the context of cancer, and at least some of these are also employed by senescent cells. This suggests that some of the approaches to therapy developed in the cancer research community may also help to enable the aged immune system to better clear lingering senescent cells. Cellular senescence arrests cell cycle progression in response to diverse stressors. When such cells persist […]

Researchers have demonstrated a sink-level conversational intelligence system that extends wireless sensor network lifetime by thirty percent while reducing security reconfiguration delay.

A former ByteDance artificial intelligence scientist’s new venture has released a life sciences AI model that the firm claims outperforms state-of-the-art systems, intensifying the increasingly crowded competition in AI-driven drug discovery. Geodesic Intelligence’s NovaAtom-Lite, an AI model designed to predict the structures and interactions of biomolecules, topped a third-party benchmark in several drug discovery tasks, founder Quanquan Gu said on social media on Wednesday. On the FoldBench...

A comprehensive scientific review highlights the overlooked global burden of lymphocytic choriomeningitis virus, detailing severe risks of congenital neurological defects and fatal donor-derived transplant infections.

Surgeons successfully resected an unusual posterior mediastinal chordoma lacking typical bone destruction in a 46-year-old patient using robot-assisted surgery.

A new N2B27-based culture medium preserves the tooth-forming capacity of mouse dental mesenchymal cells for 14 days by modulating BMP4 and osteopontin signaling.

A research team has demonstrated the first diode-pumped cryogenically cooled Yb:KGW regenerative amplifier, generating 1.28-millijoule, 467-femtosecond pulses with near-diffraction-limited beam quality at a one-kilohertz repetition rate.

A study in Biological Research shows that hypoxic culture delays senescence and preserves the therapeutic efficacy of long-term passaged human umbilical cord-derived mesenchymal stem cells in a diabetic nephropathy mouse model.

Researchers developed a Riemannian-weighted filter bank framework that enhances multiclass motor imagery brain-computer interface classification, achieving an 81.83 percent ensemble accuracy on benchmark electroencephalogram data.

A retrospective study of the first 100 organ donation procedures following euthanasia in the Netherlands yielded 408 transplanted organs while highlighting key clinical and ethical challenges.

Engineers have developed an edge AI pipeline deploying a quantized neural network to an ARM Cortex-M33 microcontroller for real-time acoustic machine health monitoring.

Acetylation of aldolase C at lysine 14 shields oligodendrocyte precursor cells from low-glucose signals to sustain the anabolic demands of myelination.

Dr. Cha Kwang-yul, head of the CHA Global Research Institutes at CHA Medical Center and CHA Bio Group, outlined an ambitious vision to use stem cells to treat intractable diseases and potentially extend human lifespan, drawing global interest at an international conference in Busan. Cha delivered his keynote address, titled "Longevity and Reproductive Aging Using K-Cells," at the 16th World Congress of the International Society for Immunology of Reproduction, held Nov. 5-8, with about 400 participants attending. The presentation focused on K-Cell, a proposed cell resource intended to support the development of treatments for intractable diseases before expanding into research on aging and longevity. Cha outlined a donor-screening strategy that combines medical and infectious disease histories with age, clinical characteristics, three generations of family medical history and whole-genome sequencing to identify cells suited to specific therapeutic purposes. He also discussed genetic

A new practice harmonization document from the European Society for Blood and Marrow Transplantation (EBMT) provides standardized definitions, diagnostic algorithms, and empirical treatment recommendations for central nervous system (CNS) infections in recipients of haematopoietic stem-cell transplantation (HSCT) and chimeric antigen receptor (CAR) T-cell therapy.

Zebrafish liver studies reveal that UHRF1 overexpression generates distinct senescent states whose expression levels dictate whether cells remain permanently arrested or escape into proliferation upon tp53 loss.

HHS awarded about $3.7 million to 40 teams developing AI prototypes for Lyme disease and other complex conditions, while stressing that the tools remain unapproved for clinical care.

A clinical study of 42 eyes found that intraoperative optical coherence tomography-guided laser tunnel creation achieved a 78.6 percent Big-Bubble success rate during deep anterior lamellar keratoplasty.

A meta-analysis of randomized controlled trials reveals mesenchymal stem cell treatment significantly lowers mortality and serious adverse events in viral lung injury.

A primary veterinary care study of over ten thousand English Cocker Spaniels identified periodontal disease as the most frequent diagnosis and highlighted coat color links to aggression.

A comparative study finds that mesenchymal stem cells isolated from nasal polyps exhibit robust differentiation potential, offering a viable biowaste source for regenerative medicine.

Surgeons successfully carried out orthotopic heart transplantation in a 41-year-old Marfan syndrome patient following staged total aortic replacement and prolonged mechanical circulatory support.

Two National Institutes of Health grants totaling more than $7 million will fund Scripps Research investigations into why protective plasma cells persist or fade over time.

A rare genetic mutation may protect against developing Parkinson's disease and Lewy body dementia, a new study from researchers at Oregon Health & Science University suggests.

A prospective evaluation demonstrates that a CRISPR-Cas13a assay targeting cell-free bacterial DNA in pleural effusion supernatant achieves 80.5 percent diagnostic sensitivity for tuberculous pleurisy.

Researchers have identified a synthetic coumarin derivative that rapidly differentiates human umbilical cord mesenchymal stem cells into functional vascular endothelial cells via MEG3 regulation.

A Frontiers in Neurology editorial synthesizes global research on screen-induced seizures, artificial intelligence diagnostics, and social stigma affecting children with epilepsy.

As people increasingly turn to artificial intelligence (AI) for health information, a new study by researchers at the Icahn School of Medicine at Mount Sinai raises questions about what happens when commercial advertising appears alongside a clinical question.

Researchers have derived the first patient-specific induced pluripotent stem cell line carrying a pathogenic HCN2 mutation, successfully generating cortical neurons and synchronized cardiomyocytes.

A comprehensive scientific review outlines how advanced biomaterial platforms target key Schwann cell signaling networks to guide cellular reprogramming and enhance peripheral nerve repair.

A study evaluating cross-species fecal microbiota transplantation demonstrated clinical remission in thirteen of twenty dogs suffering from chronic enteropathy.

The Vanderbilt Liver Transplant team recently performed three liver transplants in 12 hours, a remarkable feat that spotlights the capabilities of the Vanderbilt Transplant Center, the busiest in the nation.

Published in Cell Regeneration, the study demonstrates that transiently inhibiting the MEK/ERK signaling pathway significantly enhances this differentiation process.

As people increasingly turn to artificial intelligence (AI) for health information, a new study by researchers at the Icahn School of Medicine at Mount Sinai raises questions about what happens when commercial advertising appears alongside a clinical question. The findings were reported in the Nov. 11 online issue of The Lancet Digital Health.

A team of researchers from the Universidad Carlos III de Madrid (UC3M) has evaluated various artificial intelligence (AI) language models to simplify medical reports and adapt them into clearer language for non-expert audiences.

NEW ORLEANS — In this video from the American Academy of Ophthalmology meeting, Sharon Fekrat, MD, FACS, FASRS, highlights “exciting” gene therapy programs with phase 3 trials now underway.Fekrat, of Duke Health, detailed encouraging data on 4D-150 (4D Molecular Therapeutics), an intravitreal gene therapy, and ABBV-RGX-314 (sura-vec, Regenxbio, AbbVie), a gene therapy using subretinal delivery, both for neovascular age-related macular degeneration.“Gene therapy is getting closer to becoming a realistic treatment option for our patients with wet AMD, but it’s

A randomized experimental study of 122 dental faculty and students found no significant difference in overall radiographic diagnostic accuracy across different AI presentation formats.

Hoag researchers announced a first in the world discovery of a molecular warning signal in the blood that identifies serous tubal intraepithelial carcinoma (STIC), an early, precancerous stage of high-grade serous ovarian cancer (HGSOC).

ORLANDO — A single-injection combination of osiramestrocel and an acellular cartilage matrix improved pain and triggered favorable structural changes in knee osteoarthritis, according to data presented at ACR Convergence.In his presentation, Jae-Young Park, MD, of Cha University, Bundang Medical Center, in South Korea, said the novel therapy, which combines an umbilical cord blood-derived mesenchymal stem cell treatment with an acellular cartilage matrix, also improved function and imparted favorable changes in biomarkers associated with inflammation and cartilage turnover.“Patients

Andrew Silver / Reuters: After China's anti-corruption crackdown on hospital visits and pharma reps, drugmakers are turning to AI assistants from Alibaba and others to reach physicians  —  Drugmakers in China are seizing on a boom in digital assistants that has opened up a new — and potentially more efficient …

Researchers are exploring fetal gene editing to treat rare genetic disorders before they cause lasting damage.

A genome-wide CRISPR screen identifies FOXJ3 as an inhibitor of ferroptosis in hepatocellular carcinoma that promotes tumor progression through OTUD5-mediated stabilization of GSTP1.

A review evaluates how bioactive compounds from traditional medicine pair with engineered biomaterials to modulate immune pathways and promote bone defect repair.

As study after study reveals unexpected health benefits of GLP-1s, longevity researchers are launching trials to examine the drugs’ effects in a surprising population: healthy people.

A prospective single-center study in an African tertiary hospital found that initial implementation of the modular Versius robotic platform in urologic oncology was technically feasible with acceptable early perioperative safety.

A multimodal curriculum combining 3D printing and case-based learning significantly improved medical students' operational skills, knowledge, and diagnostic case analysis in orthopedic sports medicine.

arXiv:2611.14490v1 Announce Type: new Abstract: We show that every projective clone homomorphism from a closed function clone containing the automorphism group of a countable homogeneous Ramsey structure $\Delta$ in a finite relational language is uniformly continuous. This answers, for such structures, open questions previously raised by Barto, Bodirsky, Marimon, Pongr\'acz, and the second author in several papers (Bodirsky, Pinsker, Pongr\'acz, J. Symb. Log. 2021; Barto, Pinsker, SIAM J. Comput. 2020; Marimon, Pinsker, arXiv:2512.01086). Consequently, the polymorphism clone of a first-order reduct $\Gamma$ of $\Delta$ admits a projective clone homomorphism if and only if $\Gamma$ primitively positively interprets all finite structures; in other words, this ability of $\Gamma$ is characterised by the absence of non-trivial identities in its polymorphism clone, a purely algebraic condition.sence of non-trivial identities in its polymorphism clone, i.e., a purely algebraic condition.

A multimodal artificial intelligence framework combining CT scans, pathology slides, and tumor microenvironment markers improved survival risk prediction after surgery for esophageal squamous cell carcinoma.

A biomimetic nanoparticle that combines antibacterial, immunomodulatory, and regenerative actions could offer a more comprehensive strategy for periodontitis. Researchers developed neutrophil-macrophage hybrid membrane-coated minocycline-loaded gelatin nanoparticles (NMm@MINO) and evaluated whether the platform could control periodontal pathogens, reprogram macrophages toward a repair-associated phenotype, and support periodontal tissue repair. The nanoparticle was designed for protease-responsive drug release and tested for bactericidal activity in vitro, macrophage polarization, osteogenesis, osteoclastogenesis, fibroblast function, as well as its therapeutic effects in a ligature-induced rat model. The work supports a multi-target local therapeutic approach that addresses infection, inflammation, and tissue destruction together rather than focusing on bacterial control alone.

arXiv:2606.11337v2 Announce Type: replace Abstract: Scientific AI agents increasingly retrieve evidence, reason across sources, and synthesize conclusions used in consequential decisions. Yet, their ability to do so in high-stakes domains such as health remains unclear. We introduce SciConBench, a large-scale live benchmark of 9.21K questions and expert-written conclusions from systematic reviews to evaluate open-domain scientific conclusion synthesis in health and medical domains. The benchmark draws on an expert-validated automated evaluation pipeline that decomposes conclusions into atomic facts and measures correctness and comprehensiveness via factual precision and recall. To mitigate data leakage, we further introduce SciConHarness, a clean-room evaluation harness that equips agents with controlled web interaction to ensure valid measurement. Evaluating 8 frontier models and deep research agents, we find that factual quality remains low: under clean-room settings, the best agent

arXiv:2611.13890v1 Announce Type: new Abstract: Recent work has shown that pretrained image generators can support diverse visual tasks. Yet directly applying them to language-guided unmanned aerial vehicle (UAV) segmentation exposes a key limitation: a plausible mask may correspond to the wrong instance among small and repeated objects. We call this mismatch between mask rendering and expression-level target selection the Grounding-Rendering Gap. We present DroneSegEdit, which combines RGB proposal rendering with language-grounded, proposal-constrained verification to select supported foreground while retaining rendered geometry. DroneSegEdit adapts the open-weight LongCat-Image-Edit model using task-specific LoRA and fixed color-to-label decoding. For referring segmentation, a Language-Grounded Spatial Verifier (LGSV) reads hierarchical states from the frozen multimodal large language model backbone to derive expression-conditioned spatial evidence, which is mapped back to the

arXiv:2611.13845v1 Announce Type: new Abstract: We present Alania-2, a Turkish text-to-speech (TTS) system with two built-in voices, voice design from text descriptions, and two kinds of voice cloning. Alania-2 is a 488M-parameter model with the VoxCPM architecture, which generates continuous audio latents with a diffusion head on top of a language-model backbone. We train it from scratch on 18,195 hours of Turkish speech, 90% of which is synthetic speech produced by a larger teacher model and filtered automatically. A text normalizer rewrites numbers, abbreviations and foreign names into the words a Turkish speaker would say; without it, none of 96 test sentences with digits kept all its critical parts, such as an amount or a date, through synthesis and speech recognition, against 86 with it. On Freya-TR-Eval, a public benchmark of 495 Turkish sentences scored with automatic speech recognition, Alania-2 reaches a word error rate of 1.44%, compared with 5.99% for our previous system.

arXiv:2611.13039v1 Announce Type: new Abstract: Reliable medical laboratory automation requires robots to complete entire workflows in protocol order while handling changes during execution. A robot may execute each motion correctly yet fail the workflow by confusing visually similar stages or stalling after human intervention. We present Robo-MLT, a dual-system framework that couples explicit workflow monitoring with learned action generation. A vision--language planner composes an ordered atomic-skill sequence from the protocol and the initial workspace observation. A multiframe execution monitor detects when the active skill has completed or become infeasible, then advances the workflow or triggers replanning. A skill-conditioned vision--language--action policy generates the manipulation trajectories, and an asynchronous runtime coordinates it with the monitor. We evaluate Robo-MLT against four policy baselines and a VLM-based monitor baseline on blood gas analysis and blood sample

A scoping review led by Georgetown University researchers found that only 13 percent of published articles examining artificial intelligence and health equity provided a specific definition of health equity.

A review in Skin indicates that artificial intelligence can assist with dermatological diagnosis and treatment planning, but persistent dataset imbalances and limited external validation remain key hurdles.

Although artificial intelligence now nominates a substantial share of Alzheimer's disease pipeline candidates, translating computational drug repurposing into clinical efficacy requires rigorous pharmacological validation.

A pilot clinical study indicates that fecal microbiota transplantation may aid intestinal recovery and alleviate symptoms in patients convalescing from severe pneumonia.

A comprehensive review reveals that deep learning artificial intelligence systems achieve over ninety percent accuracy in bladder cancer detection, though widespread clinical adoption still faces critical validation hurdles.

A multicentre cohort study found recent trimethoprim-sulfamethoxazole prophylaxis in kidney transplant recipients was associated with higher resistance rates during subsequent bloodstream infections.

UCLA Health performs its first single-port robotic lobectomy, using a new technique that could reduce pain and make recovery easier for patients with lung cancer.

A major review of more than 350 studies suggests that eating less protein could slow aging, improve metabolic health, and potentially extend lifespan, challenging the widespread belief that more protein is always better. Researchers warn that many sedentary adults may be consuming too much protein, while emphasizing that individual needs depend on age and physical activity.

A cross-sectional study of 362 pregnant women in Istanbul found no significant association between food neophobia and adherence to the Mediterranean diet.