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In a groundbreaking advancement for gene therapy, researchers have unveiled two novel bioengineered AAV8 vectors—HMR-001 and its codon-optimized counterpart HMR-001z—that demonstrate remarkable efficacy in restoring hemostasis in hemophilia A, a severe bleeding disorder caused by factor VIII deficiency. This pioneering study addresses the critical limitations of current hemophilia therapies as well as earlier gene delivery […]
Google Health Premium vs. Basic Features: Worth Paying For? Droid LifeIntroducing the all-new Fitbit Air blog.googleGoogle Finally Made the Fitness Tracker Apple and Whoop Wouldn’t Gear PatrolFitbit 4.69 rolls out with redesign of focus stats and logging 9to5GoogleGoogle Fitbit Air: 6 unique features that could tempt us to switch Mashable
Google Health Premium vs. Basic Features: Worth Paying For? Droid LifeIntroducing the all-new Fitbit Air blog.googleGoogle Finally Made the Fitness Tracker Apple and Whoop Wouldn’t Gear PatrolFitbit 4.69 rolls out with redesign of focus stats and logging 9to5GoogleGoogle Fitbit Air: 6 unique features that could tempt us to switch Mashable
Google рассказала новые подробности о сервисе Google Health Coach, который должен стать персональным наставником в вашем кармане. Он будет создавать индивидуальные рекомендации для каждого пользователя, анализируя с помощью состояния состояния здоровья, питания и т. д.
Mouse eyes photosynthesize after plant-to-animal transplant NatureScientists Turn Mouse Eyes Into Solar Panels Using Spinach YahooNUS Scientists Develop Dry Eye Cure with Plant Power Mirage News
Mouse eyes photosynthesize after plant-to-animal transplant NatureScientists Turn Mouse Eyes Into Solar Panels Using Spinach YahooNUS Scientists Develop Dry Eye Cure with Plant Power Mirage News
The acquisition, Weights.gg, was a sort of social network for creating and sharing artificial intelligence algorithms.
The acquisition, Weights.gg, was a sort of social network for creating and sharing artificial intelligence algorithms.
In a groundbreaking leap forward in cardiovascular research, a team of scientists has unveiled an unprecedented single-cell atlas of perivascular adipose tissue, illuminating the intricate cellular landscape that surrounds blood vessels. This comprehensive cellular map highlights a previously underappreciated population of CD55-positive adipose-derived stem cells, which emerge as pivotal regulators of vascular remodeling in the […]
In a groundbreaking study recently published in Nature Communications, researchers have deployed CRISPR technology to revolutionize environmental detection of Burkholderia pseudomallei, the bacterium responsible for melioidosis—a severe infectious disease predominantly affecting tropical regions. This innovative approach has uncovered previously unrecognized sanitation vulnerabilities in northeast Thailand, revealing critical insights into the environmental reservoirs of this pathogen […]
The accumulation of senescent cells with age is clearly an important aspect of degenerative aging. Senescent cells contribute to chronic inflammation and disrupt tissue structure and function. Of the early senolytic treatments shown to clear a fraction of senescent cells in the tissues of aging, only the dasatinib and quercertin combination has undergone initial clinical trials in human patients, and even there the trials are small and the doses relatively low. Data is promising but not conclusive. The field has moved past the initial interest in clearance without actually implementing that initial interest, albeit a number of companies are working towards clinical trials for their varied senolytic strategies. Meanwhile the research is more focused on understanding differences between senescent cells and has, perhaps, become overly […]
FRIDAY, May 15, 2026 — The U.S. Food and Drug Administration (FDA) has approved an AI-powered early warning system to detect sepsis, one of the deadliest infections for hospital patients. The tool, developed at Johns Hopkins University (JHU)...
A groundbreaking review published in the latest issue of Aging-US is reshaping our understanding of cellular senescence and its role in aging, offering a highly nuanced roadmap for precision anti-aging therapies. Spearheaded by researchers Jian Deng and Dong Yang at Sichuan University’s West China Hospital, the study presents a paradigm shift from viewing senescent cells […]
As more people turn to chatbots for medical guidance, the technology is revealing both its promise and its risks
Ученые из компании Editas Medicine представили результаты доклинических экспериментов CRISPR-терапии для лечения гиперлипидемии. Однократная инъекция препарата показала резкое снижение «плохого» холестерина – липопротеинов низкой плотности – и сохраняла терапевтический эффект в течение полугода. Отсутствие неблагоприятных побочных эффектов открывает удивительные возможности в лечении и профилактике сердечно-сосудистых заболеваний.
NEW ORLEANS — Transplant social workers identified top risk factors and psychosocial interventions needed for evaluating kidney transplant candidacy, according to data presented at the National Kidney Foundation Spring Clinical Meetings.At the Society for Transplant Social Workers (STSW) annual meeting in 2024, members said they were frustrated about the lack of standardization and limited role of social workers in psychosocial assessments of transplant candidacy, according to Lara Tushla, LCSW, NSW-C, FNKF, CCTSW, a kidney and pancreas transplant social worker at Rush University Medical
The CEO of Caszyme, a biotech company in Vilnius, Lithuania, presented details of Cas12l, a novel compact Cas nuclease with a variety of potential research and therapeutic applications. The post ASGCT 2026: AI-Optimized Cas12l Gene Editor Offers Compact Cas9 Alternative appeared first on GEN - Genetic Engineering and Biotechnology News.
Beverly Davidson, PhD, chief scientific strategy officer at Children's Hospital of Philadelphia, shares her research including a novel gene therapy approach for Huntington's disease. The post ASGCT 2026: Beverly Davidson Offers Vehicle and Route for Huntington’s Disease Gene Therapy appeared first on GEN - Genetic Engineering and Biotechnology News.
A team of engineers at the University of Florida has developed a new form of CRISPR technology that could make diagnostics and treatments safer, more precise, and more affordable, while opening the door to entirely new ways of controlling disease.
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. How Chinese short dramas became AI content machines China’s short drama industry is fueled by bite-sized, melodramatic, and smutty shows built for smartphone scrolling. Now, many are being made entirely with…
Researchers here report an surprising, interesting, but not immediately useful discovery relating to the interaction of the immune system with wound healing in aged skin. Regeneration in aged skin is impaired, and non-healing wounds are one consequence of this impairment. The researchers found that priming aged skin with a dose of lipopolysaccharide, a toxic bacterial product that the immune system reacts to, improves skin regeneration after later injury. In the real world injuries are hard to predict ahead of time, so a better understanding how the observed changes in immune cell behavior provoked by this intervention are regulated is required in order to develop a form of therapy that usefully recreates the effects. Tissue repair is often hampered during aging. Worldwide, chronic wounds in elderly […]
The platform, called ΨDNA, reprograms Cas12 nucleases to recognize and act on RNA using a DNA-based guide scaffold. In human cell lines, ΨDNA achieved 70–95% knockdown of endogenous RNA transcripts. The post DNA‑Guided CRISPR Suggests a New Direction for RNA Editing appeared first on GEN - Genetic Engineering and Biotechnology News.
arXiv:2605.13902v1 Announce Type: new Abstract: Breast cancer incidence rises with age and peaks across the menopausal transition, yet why some postmenopausal lobules persist, and why that persistence predicts cancer risk, remains unresolved. Incomplete age-related lobular involution is one of the strongest tissue-level predictors of subsequent breast cancer, but it is still commonly viewed as passive failure of hormonally driven regression. This Review proposes a different framework: persistent lobules are maintained by an active reserve niche that outlasts its reproductive function. By integrating breast epidemiology, mammary stromal biology, cellular senescence, immune surveillance, and comparative reserve systems in skeletal muscle, hematopoiesis, and postmenopausal endometrium, we argue that menopause is a biological control point at which tissue fate diverges. Efficient clearance of senescent cells permits lobular regression to complete, whereas impaired immune surveillance may
arXiv:2605.14669v1 Announce Type: new Abstract: In this paper, we study the asymptotic behavior of Jacobi biorthogonal polynomials. A Darboux-type formula is established using the method of steepest descent. In the proof, we construct an appropriate contour to apply the Rodrigues formula. Our result reduces to the classical Darboux formula in the orthogonal case.
arXiv:2605.14941v1 Announce Type: cross Abstract: Electroencephalogram (EEG) signals are highly susceptible to artifacts, resulting in a low signal-to-noise ratio which makes extraction of meaningful neural information challenging. Artifact Subspace Reconstruction (ASR) is one of the most widely used artifact filtering techniques in EEG-based BCI applications, owing to its real-time applicability. ASR reconstructs artifact-free signals by operating in Principal Component (PC) space within sliding windows. However, ASR performance is critically sensitive to its threshold parameter - an incorrect threshold risks removing task-relevant neural features alongside artifacts. Furthermore, since PCs are linear combinations of all channels, subspace reconstruction in PC space may alter the underlying data structure, potentially discarding essential neural information. To address these limitations, we propose nASR, a novel end-to-end trainable Keras layer that jointly optimizes artifact
arXiv:2605.14883v1 Announce Type: cross Abstract: Mild traumatic brain injury (mTBI) is a prevalent condition that remains difficult to diagnose in its early stages. Oculomotor dysfunction is a well-established marker of mTBI, motivating the development of portable tools that capture both eye-movement behavior and underlying neurophysiology. In this work, we present an initial framework that integrates electroencephalogram (EEG) with augmented-reality (AR)-based Vestibular/Ocular Motor Screening (VOMS) tasks to estimate subject-specific ocular response times. Pre-processed EEG signals, obtained through band-pass filtering and average referencing, are analyzed using a Redundant Discrete Wavelet Transform (RDWT)-driven deep neural framework. The RDWT coefficients are subjected to trainable zero-phase convolutional filtering and reconstructed into the time domain via inverse RDWT, followed by channel-wise temporal and spatial filtering using 2D convolution layers and
arXiv:2605.14865v1 Announce Type: new Abstract: AI agents execute complex multi-step processes, but current evaluation falls short: outcome metrics report success or failure without explaining why, and process-level approaches struggle to connect failure types to their precise locations within long, structured traces. We present a holistic agent evaluation framework that pairs top-down agent-level diagnosis with bottom-up span-level evaluation, decomposing analysis into independent per-span assessments. This decomposition scales to traces of arbitrary length and produces span-level rationales for each verdict. On the TRAIL benchmark, our framework achieves state-of-the-art results across all metrics on both GAIA and SWE-Bench, with relative gains over the strongest prior baselines of up to 38% on category F1, up to 3.5x on localization accuracy, and up to 12.5x on joint localization-categorization accuracy. Per-category analysis shows our framework leading in more error categories
arXiv:2605.14165v1 Announce Type: new Abstract: False data injection (FDI) attacks on Internet of Medical Things (IoMT) sensor streams falsify vital signs in transit, threatening patient safety and defeating clinical monitoring systems that lack cyber-physical anomaly detection capability. Existing deep learning detectors conflate inter-sensor spatial correlations with temporal dependencies in a shared latent space, preventing disentanglement of the distinct spatial and temporal signatures that FDI attacks imprint simultaneously; no current method exploits domain knowledge to constrain outputs against physiologically impossible attack patterns. We propose DSTAN-Med, a supervised framework comprising a Dual-channel Attention Mechanism (DAM) that routes multivariate sensor windows through independent sensor-wise (SWA) and time-wise (TWA) self-attention pathways operating on orthogonal tensor axes, a residual 1D-CNN block for local temporal feature extraction, and a zero-parameter
arXiv:2605.14106v1 Announce Type: new Abstract: We investigate whether behavior cloning is sufficient to produce active perception in a structured object-finding task. A low-cost robot arm equipped with a wrist-mounted egocentric RGB camera must reposition to center a partially visible plant before triggering a grasp signal, requiring actions that improve future observations. The model predicts joint commands directly from low-resolution RGB images under closed-loop control. We show that low-resolution egocentric vision is sufficient for reliable task completion and that predicting relative joint deltas substantially outperforms absolute joint position prediction in our setting. These results demonstrate that visually grounded active perception can emerge from behavior cloning in a reproducible setting.
A groundbreaking advancement in genetic engineering has emerged from a team of researchers at the University of Florida, promising to reshape the landscape of disease diagnostics and therapeutic interventions. Their pioneering work, recently published in the prestigious journal Nature Biotechnology, unveils the first-ever CRISPR system guided by DNA instead of the conventionally used RNA. This […]
Она использует короткие молекулы ДНК для распознавания определенных молекул РНК в человеческих клетках
A team of engineers at the University of Florida has developed a new form of CRISPR technology that could make diagnostics and treatments safer, more precise, and more affordable, while opening the door to entirely new ways of controlling disease.
Breakthrough pancreatic cancer drug sparks huge patient demand at US clinics The IndependentHow an ‘Impossible’ Idea Led to a Pancreatic Cancer Breakthrough The New York TimesUS cancer clinics scramble to get experimental Revolution Medicines pancreatic cancer drug ReutersShe's trying to outrun pancreatic cancer. Breakthrough treatments give her hope NPRThe slippery protein problem Works in Progress Magazine
Breakthrough pancreatic cancer drug sparks huge patient demand at US clinics The IndependentHow an ‘Impossible’ Idea Led to a Pancreatic Cancer Breakthrough The New York TimesUS cancer clinics scramble to get experimental Revolution Medicines pancreatic cancer drug ReutersShe's trying to outrun pancreatic cancer. Breakthrough treatments give her hope NPRThe slippery protein problem Works in Progress Magazine
Paul Boyer, a psychotherapist for Kaiser Permanente in Oakland, California, is experiencing the AI revolution firsthand. He's a little underwhelmed. The health giant has rolled out a new suite of note-taking software, made by health care AI pioneer Abridge, intended to summarize a patient's visit at supersonic speed. For many clinicians, the technology soothes one of the persistent headaches of their lives—administration and paperwork.
Aerobic exercise has long been celebrated for its sweeping benefits on human health, enhancing cardiovascular fitness, metabolic regulation, and mental well-being. However, the molecular and cellular underpinnings that link aerobic physical activity to reduced cancer risk remain enigmatic despite decades of epidemiological evidence. A transformative perspective emerging in the field now posits adult stem cells […]
Made-up therapy referrals, incorrect prescriptions among the common mistakes.
A gene therapy designed by Encoded Therapeutics reduced seizures by 76% in children with Dravet syndrome, a severe neurodevelopmental disorder. The remarkable reduction was observed only in three patients treated with the second-highest of four ...
The European Union’s (EU’s) European Health Data Space Regulation (EHDS), which provides a comprehensive framework for health data governance, positions artificial intelligence (AI) innovation as a strategic objective (1). However, although the EHDS enables cross-border access to health data, it does not create comparable access mechanisms for the AI models trained on those data. To ensure useful and reproducible AI results, the EU should supplement the regulation with a dedicated framework for AI model sharing.
Jeffrey Dastin / Reuters: Anthropic and Gates Foundation pledge $200M to use AI in health and education initiatives; the foundation signed a similar, $50M deal with OpenAI in January — Anthropic and the Gates Foundation have pledged $200 million to back artificial intelligence-related public goods and areas including health …
US cancer clinics scramble to get experimental Revolution Medicines pancreatic cancer drug ReutersHow an ‘Impossible’ Idea Led to a Pancreatic Cancer Breakthrough The New York TimesNew pancreatic cancer drug sees patients live almost twice as long in clinical trial WBAL-TVShe's trying to outrun pancreatic cancer. Breakthrough treatments give her hope NPRASCO 2026: All Eyes Are on Daraxonrasib and a Wave of Novel Targeted Therapies in GI Malignancies OncLive
US cancer clinics scramble to get experimental Revolution Medicines pancreatic cancer drug ReutersHow an ‘Impossible’ Idea Led to a Pancreatic Cancer Breakthrough The New York TimesNew pancreatic cancer drug sees patients live almost twice as long in clinical trial WBAL-TVShe's trying to outrun pancreatic cancer. Breakthrough treatments give her hope NPRASCO 2026: All Eyes Are on Daraxonrasib and a Wave of Novel Targeted Therapies in GI Malignancies OncLive
A daily multivitamin may help slow biological aging, according to researchers studying older adults in a large clinical trial. After two years, participants taking multivitamins showed slower aging in several DNA-based “epigenetic clocks,” with the effect equal to about four months less biological aging. People who started out biologically older than their actual age appeared to benefit the most. The findings hint that a simple supplement could play a role in healthier aging.
AI therapy and AI mental health tools are transforming emotional support, but experts warn the ethics of AI in healthcare must keep pace with innovation, privacy, and patient safety.
Muscle stem cells, which are crucial for building new muscle, don’t work as well as we get older, but giving them an artificial boost could rejuvenate them
Physicians at Penn Medicine said they're thinking of how to use AI to train doctors. The idea came out of a $1.1 million grant Penn Medicine won in January through an education grant program with ...
Isomorphic Labs Grabs $2.1 Billion for AI Drug Discovery Google-backed company grabs global attention by raising funds that expand its AI Drug Discovery. In the era of Artificial Intelligence making its way into the pharma industry, this announcement sets the bar for further development in drug discovery. Isomorphic Labs, a London-based biotech company, has secured […] The post Google-Backed Isomorphic Labs Secures $2.1 Billion to Push AI Drug Discovery Forward appeared first on BioTecNika.
An NHS trust in Kent and Medway is piloting PARO, a therapeutic robot baby seal, to help patients with learning disabilities feel more comfortable during appointments.
Plasma levels of symmetric dimethylarginine are independently associated with an increased risk for mortality in adult kidney transplant recipients, a prospective study finds.
Scientists have discovered that transplanted stem cell-derived brain cells may do far more than simply survive after a stroke. A stem cell treatment helped mice recover from strokes by rebuilding damaged brain connections, restoring blood vessels, and improving movement, according to new research from the University of Zurich and the University of Southern California. The [...]
Regenxbio said Thursday that its Duchenne muscular dystrophy gene therapy met the bar in a pivotal study, and it’s aiming for FDA approval in 2027. The biotech hopes to be the second company to commercialize ...
The work noted here might be taken as a companion piece to a recent paper on eusociality as a driver of the evolution of exceptional longevity in a wide variety of clades, not just mammals. Here, researchers take a broad look across mammalian species that exhibit a variety of different type of social organization, and find a correlation with species longevity. While thinking about this, one might also look at the evidence for mating strategies to drive the evolution of longevity; one might think that social organization has a large impact on mating strategy. At root, one might ask how all of these various parameters and their outcomes affect the trade-off between growth and maintenance in individuals; as a rule, species that mature faster can […]
arXiv:2605.13070v1 Announce Type: new Abstract: The orientation of cell division is a major determinant of three-dimensional plant morphogenesis. Whether and how a simple division orientation rule explains the establishment of symmetric body plans is a fundamental question. Testing such hypotheses is facilitated by a modeling framework that combines realistic three-dimensional cell mechanics, irreversible cell-wall growth, and a deformable tissue geometry. We recently introduced such a framework, a 3D mechano-geometric multicellular model of apical stem cell-driven morphogenesis. Here we document how the model is built from physiological and computational perspectives. We describe the triangulated thin-shell representation of cells, the treatment of turgor pressure, cell-wall elasticity and strain-driven wall growth, the cell-division algorithm together with its two pluggable division-rule implementations, and the remeshing operations that keep the triangulation well-conditioned as
arXiv:2605.13070v1 Announce Type: cross Abstract: The orientation of cell division is a major determinant of three-dimensional plant morphogenesis. Whether and how a simple division orientation rule explains the establishment of symmetric body plans is a fundamental question. Testing such hypotheses is facilitated by a modeling framework that combines realistic three-dimensional cell mechanics, irreversible cell-wall growth, and a deformable tissue geometry. We recently introduced such a framework, a 3D mechano-geometric multicellular model of apical stem cell-driven morphogenesis. Here we document how the model is built from physiological and computational perspectives. We describe the triangulated thin-shell representation of cells, the treatment of turgor pressure, cell-wall elasticity and strain-driven wall growth, the cell-division algorithm together with its two pluggable division-rule implementations, and the remeshing operations that keep the triangulation well-conditioned as
arXiv:2605.13630v1 Announce Type: new Abstract: This study significantly advances multi-texture synthesis using Neural Cellular Automata (NCAs) by introducing a novel training methodology that enables robust self-regeneration of textures in damaged regions. This inherent healing mechanism, essential for dynamic and adaptive systems, extends beyond traditional computer graphics applications, highlighting the fundamental self-organizing properties of NCAs. Furthermore, we present a versatile grafting technique, enabling the seamless combination of distinct textures. This is achieved efficiently during the inference phase, without requiring specialized retraining, through precise initialization of the NCA's genome channels. Our findings demonstrate the generation of high-quality, complex textures with fluid transitions, showcasing a powerful and efficient paradigm for dynamic texture composition and self-repair in autonomous systems.
arXiv:2605.13318v1 Announce Type: new Abstract: Chatbot usage has increased, including in fields for which they were never developed for--notably mental health support. To that end, we introduce Validations of Ethical and Responsible AI in Mental Health (VERA-MH), a novel clinically-validated evaluation for safety of chatbots in the context of mental health support. The first iteration of VERA-MH focuses on Suicidal Ideation (SI) risks, by assessing how well chatbots can responds to users that might be in crisis. VERA-MH is comprised of three steps: conversation simulation, conversation judging and model rating. First, to simulate conversations with the chatbot under evaluation, another chatbot is tasked with role-playing users based on specific personas. Such user personas have been developed under clinical guidance, to make sure that, among others, multiple risk factors, demographic characteristics and disclosure factors were represented. In the judging step, a second support
A next-generation cancer therapy being developed at McMaster University has shown early promise as a treatment candidate for glioblastoma, the most aggressive and most common type of primary brain cancer in adults.
Jared Perlo / NBC News: OpenEvidence, an AI-powered medical search tool, says it's used by two-thirds of US physicians, or ~650K doctors, and an additional 1.2M doctors internationally — OpenEvidence, an AI-powered medical search tool, has become a fast friend to America's doctors and is now used by nearly two-thirds of physicians.
In a world first, a research team at the University of Zurich has successfully treated mice carrying an inherited form of epilepsy.
Scientists at UMass Chan Medical School have pioneered a groundbreaking gene editing technology named “prime assembly,” which challenges the limitations of traditional genome editing methods by enabling the precise and efficient insertion of exceptionally large DNA segments into the human genome. This innovative approach merges two sophisticated molecular techniques—prime editing and Gibson assembly—propelling the field […]
Researchers at the University of Reading have uncovered a compelling new approach to combat glioblastoma, the most aggressive and lethal form of brain cancer in adults. Their groundbreaking work focuses on the unique properties of stem cells derived from the oral mucosa—the lining of the mouth—which secrete a complex mixture of proteins and extracellular vesicles […]
Stem cells found in the lining of the mouth could help make the most aggressive form of brain cancer easier to treat, according to new research from the University of Reading. The stem cells release a mixture of proteins and tiny particles into their surroundings, and when tested on human brain cancer cells transplanted into mouse brain tissue, they slowed the cancer's growth, made it harder for cancer cells to move around, and reduced the number and size of tumors that formed. When administered alongside the primary chemotherapy treatment for this cancer, they led to greater tumor reduction without harming the surrounding healthy brain tissue.
In recent years, the field of ophthalmology has witnessed a revolutionary transformation propelled by the integration of artificial intelligence (AI) with multimodal data analytics. The human eye, far more than a mere optical organ, serves as a vital microcosm that reflects both systemic microcirculation and neural activity. Capitalizing on this dual role, researchers are now […]
BOSTON — Early last year, startup iECURE’s experimental gene therapy seemingly cured a baby of a life-threatening genetic disease. But new results testing the same therapy in a larger number of babies show ...
Leerink analysts lifted J&J shares to a buy equivalent from hold on Wednesday, citing the company's slate of new drugs.
SAI created its Regenerating Together program to make global regenerative agriculture standards adaptable at the local level. The post Global frameworks for regenerative agriculture still need local context, says SAI appeared first on AgFunderNews.
Jason Collins, the first openly gay NBA player, dies at 47 from brain cancer NBC NewsJason Collins, First Active N.B.A. Player to Come Out as Gay, Dies at 47 The New York TimesJason Collins, first openly gay NBA player, dies after glioblastoma battle Yahoo SportsJason Collins, 1st openly gay NBA player, dies of brain cancer at 47 ESPNJason Collins, NBA's first openly gay player, dead at 47 Fox News
Jason Collins, the first openly gay NBA player, dies at 47 from brain cancer NBC NewsJason Collins, First Active N.B.A. Player to Come Out as Gay, Dies at 47 The New York TimesJason Collins, first openly gay NBA player, dies after glioblastoma battle Yahoo SportsJason Collins, 1st openly gay NBA player, dies of brain cancer at 47 ESPNJason Collins, NBA's first openly gay player, dead at 47 Fox News
New Phase I/II POLARIS data presented at the ASGCT Presidential Symposium show ETX101 delivering durable seizure reduction and early neurodevelopmental gains in children with SCN1A+ Dravet syndrome, highlighting the promise of targeted gene regulation therapy. The post Gene Therapy ETX101 Improves Seizures and Neurodevelopment in Dravet Syndrome in Phase I/II appeared first on GEN - Genetic Engineering and Biotechnology News.
RNA testing may help assess the consequences of common environmental mold.
Researchers have developed artificial intelligence (AI) models that can scrutinize electronic health records (EHR) and electrocardiograms to identify individuals in the general population at elevated risk for sudden cardiac arrest - a condition that causes more than 400,000 U.S. deaths annually and has a survival rate of only 10%.
Healthy aging habits and smart midlife health choices support longevity, improve prevention, and help reduce disease risk for better aging outcomes in later life.
arXiv:2605.11963v1 Announce Type: new Abstract: This paper examines what it means for a medical AI system to be right by grounding the question in a specific clinical context: the automatic classification of plasma cells in digitized bone marrow smears for the diagnosis of multiple myeloma. Drawing on philosophy of science and research ethics, the paper argues that correctness in medical AI is not a singular property reducible to benchmark performance, but a multi-dimensional concept involving the availability of expertly labeled medical datasets, the explainability and interpretability of model outputs, the clinical meaningfulness of evaluation metrics, and the distribution of accountability in human-AI workflows. As such, the paper develops this argument through four interrelated themes: the instability of ground truth labels, the opacity of overconfident AI, the inadequacy of standard clinical metrics, and the risk of automation bias in time-pressured clinical settings.
arXiv:2605.11502v1 Announce Type: new Abstract: Accurately and consistently indexing biomedical literature by publication type and study design is essential for supporting evidence synthesis and knowledge discovery. Prior work on automated publication type and study design indexing has primarily focused on expanding label coverage, enriching feature representations, and improving in-domain accuracy, with evaluation typically conducted on data drawn from the same distribution as training. Although pretrained biomedical language models achieve strong performance under these settings, models optimized for in-domain accuracy may rely on superficial lexical or dataset-specific cues, resulting in reduced robustness under distributional shift. In this study, we introduce an evaluation framework based on controlled semantic perturbations to assess the robustness of a publication type classifier and investigate robustness-oriented training strategies that combine entity masking and
While most clinicians are aware of the link between immunosuppression and poor outcomes, this study validates that link and clarifies the type of immunosuppression associated with the greatest risk.
Amber Tong / Bloomberg: Metis TechBio, a biotech company using AI to deliver and formulate drugs, surged as much as 185% in its Hong Kong market debut after raising ~$270M in its IPO — Shares of Metis TechBio Co, a biotechnology company using artificial intelligence to deliver and formulate drugs …
A team led by USC Stem Cell scientist Zhongwei Li, PhD, has produced some of the most complex and mature lab-grown kidney models to date.
A new study has demonstrated the regenerative effect that solar farms can have on degraded and depleted land, by sheltering it from harsh winds, pushing down surface temperatures, and boosting soil moisture. The post Solar farms can help to regenerate land while generating energy, new study finds appeared first on Renew Economy.
As blood stem cells age, their lysosomes become overactive and damaged, triggering inflammation and weakening the body’s ability to regenerate healthy blood and immune cells. By calming this cellular “overdrive,” researchers restored the stem cells’ youthful function, dramatically boosting their ability to regenerate and produce balanced blood cells.
Connie Loizos / TechCrunch: The US' Centers for Medicare & Medicaid Services is testing ACCESS, an outcome-based payment model for AI-driven medical care, with 150 tech companies — Neil Batlivala has spent seven years building a healthcare company that most of the tech industry has never heard of and that serves …
Artificial intelligence has shortened drug development from years to just 18 months, the founder of METiS TechBio said, as the AI-driven drug design start-up made its Hong Kong debut on Wednesday amid strong investor appetite for AI-related stocks in the city. “We see ourselves like a SpaceX-style company,” Lai Tsai-Ta, co-founder and CEO of METiS TechBio, who obtained a PhD from the Massachusetts Institute of Technology in the US, said. “We use AI algorithms to design a large number of...
Lung cancer remains one of the leading causes of cancer-related deaths worldwide, making early and accurate diagnosis essential for improving patient outcomes.
A large retrospective cohort study of adult female breast cancer patients found that GLP-1 receptor agonist use was associated with better all-cause survival and recurrence-free survival in patients with obesity or type 2 diabetes. The strongest associations were seen versus non-use in obesity and versus insulin or metformin in type 2 diabetes, while comparisons with SGLT2 inhibitors were less consistent and require further study.
There is no governmental mechanism to pay for an AI agent that monitors a patient between visits, calls to check in, coordinates a housing referral, or makes sure someone picks up their medication. ACCESS creates that mechanism for the first time.
The National Institute of Neurological Disorders and Stroke (NINDS) has awarded Toloo Taghian, PhD, an assistant professor of genetic and cellular medicine as well as radiology at UMass Chan Medical School, a significant five-year grant totaling $3.2 million. This grant is designated to propel groundbreaking research into gene therapy solutions targeting UBA5 disorder, a rare […]
In a groundbreaking advancement that promises to revolutionize both regenerative medicine and kidney disease research, a team led by Dr. Zhongwei Li at USC Stem Cell has developed some of the most sophisticated lab-grown kidney models ever created. These synthetic structures, known as human synthetic kidney organoids (hSKOs) or human kidney progenitor assembloids (hKPAs), emulate […]
A Phase I/II clinical trial shows that a stem cell transplant that removes CD33 from donor cells using CRISPR can prevent cancer recurrence. The post Acute Myeloid Leukemia Therapy Improved by CRISPR Stem Cell Transplant appeared first on GEN - Genetic Engineering and Biotechnology News.
In this episode of Voices of the Valley, we explore the future of regenerative agriculture through the lens of stewardship, conservation and long-term resilience. Hosted by Western Growers’ Jeana Cadby, ... Read More The post Regenerative Roots: Farming for the Next 100 Years appeared first on AgNet West.
An international research group recently demonstrated that the antibody NG101 promotes the regeneration of damaged spinal cord tissue.
Researchers from the Hebrew University of Jerusalem and the Weizmann Institute of Science have identified a previously unrecognized defense mechanism in the intestine, showing that intestinal stem cells can actively respond to Salmonella infection and help protect the gut from bacterial invasion.