Headlines

How a team of AIs discovered a promising lung-cancer drug  NatureVirtual biotech company puts thousands of AI scientist agents to work on drug discovery  Phys.orgA.I. Agents as ‘Co-Scientists’? This Lab Says They Could Speed Drug Research.  The New York TimesAI Pharmaceutical Company with 37,000 Researchers Emerges  조선일보AI Agents Collaborate to Streamline Drug Discovery  Inside Precision Medicine

How a team of AIs discovered a promising lung-cancer drug  NatureVirtual biotech company puts thousands of AI scientist agents to work on drug discovery  Phys.orgA.I. Agents as ‘Co-Scientists’? This Lab Says They Could Speed Drug Research.  The New York TimesAI Pharmaceutical Company with 37,000 Researchers Emerges  조선일보AI Agents Collaborate to Streamline Drug Discovery  Inside Precision Medicine

GenCelix (Founder & CEO Minji Kang), a company specializing in cell technology and manufacturing, announced that it signed a trilateral memorandum of understanding (MOU) with DKMG (President Hyungsuk Kim) and Japan-based KOHJIN BIO (Founder & Chairman Takahito Nakamura) on Sept. 7, at Hilton Garden

Researchers created xenocortical mice by transplanting human cortical organoids into animals genetically depleted of much of their native cortex, allowing the human tissue to occupy most of the available cortical space and form anatomical connections throughout the host nervous system. The grafts developed diverse cortical cell types, including L5-ET and VEN-like neurons, generated organized neural activity, and produced measurable cellular and behavioral responses to hypoxic injury.

Danaher companies Integrated DNA Technologies (IDT), a global leader in genomics, and Aldevron, a premier manufacturing partner for DNA, RNA, and protein, today announced the launch of research grade S.p. Cas9 mRNA in wild type and SpyFi™ high-fidelity formats.

arXiv:2609.20499v1 Announce Type: new Abstract: The paper presents a numerical approach for the end-effector trajectory smoothing of a parallel robot designed for minimally invasive pancreatic surgery. The approach is tailored for real-time master-slave control architecture and uses a 3D space mouse for command input for velocity control. The trajectory smoothing is achieved by generating S-curves in the end-effector velocity fields, thus controlling the accelerations, which in turn reduces tissue trauma in the minimally invasive procedures. Real-time control is enabled by segmenting the S-curves based on the command inputs from the 3D space mouse. A special case is considered where the acceleration time is constant for all command inputs. Numeric results demonstrate stable transitions (without abrupt changes) in both the end-effector parameter space and in the active joints parameters, thereby validating the proposed approach. Further work aims to test the approach on an experimental

arXiv:2609.20275v1 Announce Type: new Abstract: Hybrid brain-computer interface (BCI) systems that integrate electroencephalography (EEG) and electromyography (EMG) signals have shown significant potential in improving the reliability of motor imagery (MI) classification, particularly in neuro-rehabilitation applications. However, identifying informative EEG-EMG channel pairs that effectively capture corticomuscular interactions remains a challenging problem, as existing approaches typically rely on manually predefined channel combinations that may not generalise across subjects. In this work, a data-driven EEG-EMG pair selection framework is proposed, in which channel pair selection is formulated as a constrained bi-objective optimisation problem. The proposed method jointly maximises the spatial relevance of EEG channels with respect to motor cortex regions and the corticomuscular coupling strength between EEG and EMG signals, and is solved using the NSGA-II to automatically

arXiv:2609.20273v1 Announce Type: new Abstract: Non-invasive brain-computer interfaces (BCIs) and eye-tracking technologies offer promising communication pathways; however, motor imagery (MI)-based BCIs often suffer from low discriminability and high inter-subject variability. To mitigate these issues, this study investigates the impact of visual fixation on neural response stability in both standalone MI and hybrid MI-eye tracking systems. We then propose a novel asynchronous hybrid paradigm that streamlines user intent by utilising eye-tracking for direct selection, followed by MI-based confirmation, significantly reducing the operational steps required by conventional systems. The paradigm was evaluated with 15 healthy participants using a 16-channel EEG system. Results show that MI-related information is predominantly localised within motor cortex regions, with limited-channel configurations (SVM: 0.58) achieving performance comparable to full-montage setups (SVM: 0.54). The

arXiv:2609.19364v1 Announce Type: new Abstract: Health misinformation disproportionately harms women, yet interventions rarely address the community norms that sustain false beliefs. We test whether culturally adaptive AI-generated video in which the presenter looks like someone from her community reduces misinformation belief among low-literacy women in suburban India. In a field experiment (N=434), participants watched an AI-generated video featuring either an adaptive or neutral presenter. The culturally adaptive presenter reduced misinformation belief by 30%, nearly twice the reduction produced by the neutral presenter compared to the non-intervention control condition. Post-experiment interviews suggest women recalled the neutral condition as a generic video but recognized the adaptive presenter. Gains persisted for three weeks. The adaptive advantage was largest for beliefs reinforced by community, such as blaming women for infertility, and negligible for medical knowledge gaps,

Apple’s Rebuilt Health App Apple Watch owners testing iOS 27.2 can now see a Health Age score, an

Artificial intelligence is rapidly becoming part of how people seek, interpret, and act on health information.

China is seeing a fresh fundraising boom for AI drug developers, with start-ups including a ByteDance spin-off raising hundreds of millions of dollars this week as investors rush to back domestic challengers to Anthropic and Isomorphic Labs. Anew Labs, a Shanghai-based AI drug discovery firm that was formerly a unit of Chinese tech giant ByteDance, has raised US$290 million at a valuation of US$1.5 billion, according to an informed source. Investors included prominent venture capital firms such...

Virtual biotech company puts thousands of AI scientist agents to work on drug discovery  Phys.orgA.I. Agents as ‘Co-Scientists’? This Lab Says They Could Speed Drug Research.  The New York Times‘Virtual Biotech’ Framework Uses AI Scientists to Pursue, Probe Drug Discovery  genomeweb.comAI Agents Collaborate to Streamline Drug Discovery  Inside Precision MedicineStanford Reports 37,000-Agent Virtual Biotech System  findarticles.com

Virtual biotech company puts thousands of AI scientist agents to work on drug discovery  Phys.orgA.I. Agents as ‘Co-Scientists’? This Lab Says They Could Speed Drug Research.  The New York Times‘Virtual Biotech’ Framework Uses AI Scientists to Pursue, Probe Drug Discovery  genomeweb.comAI Agents Collaborate to Streamline Drug Discovery  Inside Precision MedicineStanford Reports 37,000-Agent Virtual Biotech System  findarticles.com

A 13-country survey found that 49% think people skilled with AI can match doctors on at least one health task. What the finding means for chatbot users.

A new open-access study introduces RiSpy, a data-driven fingerprinting framework that makes the identification of genome-edited (GE) rice lines more robust, scalable and broadly applicable. Researchers from Sciensano, together with CIRAD and DARWIN project partners, in collaboration with colleagues from Ghent University, have presented the new methodological framework for the reliable identification of genome-edited (GE) rice lines in the journal Briefings in Bioinformatics.

Patients in England with an incurable breast cancer can now access a life-extending drug on the NHS.

Enhertu, which can give patients an extra seven months to live on average, has been prescribed in Scotland for more than two years and is available.

Japan has recorded 99,763 people aged 100 and over, extending a 55-year rise, while longevity and demographic ageing increase pressure on public finances and services.

The technique opens new possibilities for investigating neurological conditions, from autism to dementia

The Next Gene-Editing Technology May Also Be the Oldest  The New York Times

The Next Gene-Editing Technology May Also Be the Oldest  The New York Times

The FDA granted accelerated approval to a rare disease gene therapy from Ultragenyx on Thursday, giving the company a much-needed boost in an otherwise difficult year. The therapy, called UX111, will be branded as Fayuvi ...

Scientists have discovered a powerful gene-targeting system in viruses. Billions of years old, VIPR seems to predate CRISPR and may be even more powerful.

PD-L1 and PD-L2 are components of immune checkpoints, widely expressed in tissues throughout the body. They act by binding to the PD-1 receptor on immune cells to suppress immune activation, and are part of the panoply of biochemical interactions that provide self-tolerance to prevent the immune system from inappropriately attacking healthy cells. Autoimmunity is a breakdown of these mechanisms. Cancerous cells abuse the strategies by which normal somatic cells are shielded from immune cell attention, and thus most research into immune checkpoints has taken place in the cancer research community. Inhibition of checkpoint interactions to unleash the immune system now forms the foundation for a number of cancer therapies, albeit that most work has focused on PD-1 and PD-L1 rather than on PD-L2. In today's […]

Scientists have discovered a powerful gene-targeting system in viruses. Billions of years old, VIPR seems to predate CRISPR and may be even more powerful.

Artificial intelligence (AI) in radiology aspires to deliver expert-level diagnosis across diverse clinical tasks, yet existing supervised strategies remain limited in scope. We developed RADAR, a generalist vision-language model trained on more than 400,...

The latest company to spin out of a Stanford Medicine lab is a biotech undertaking with 37,000 employees—and none of them are human. There's no lab space, no lunch breaks and no payroll. It's an artificial intelligence-powered virtual biotech company that's the brainchild of associate professor of biomedical data science James Zou, Ph.D., who is also the principal investigator of a virtual lab that launched in 2025, and graduate student Harrison Zhang.

Scientists have discovered a powerful gene-targeting system in viruses. Billions of years old, VIPR seems to predate CRISPR and may be even more powerful.

Many people will learn CPR using a flat-chested manikin. A 2024 study of 20 models of CPR manikins sold worldwide found that three-quarters were described as male or had no sex specified. Of the 20, only one offered a breast overlay.

Stem cell researchers have identified inflammatory pathways that may play a key role in driving kidney damage in diabetic kidney disease (DKD), pointing to potential new approaches for protecting the kidneys. Using stem cell-derived kidney organoids, Dr. Benjamin Freedman and colleagues from the University of Washington found that exposure to high sugar levels triggered inflammation and disrupted the organoids' typical kidney tissue-like structure, causing individual kidney cells to detach. These changes were reminiscent of those observed in kidney biopsies and urine samples from patients with DKD. The research was published today in the journal Stem Cell Reports.

Scientists studying Maria Branyas, who lived to 117, found signs of extreme aging alongside biological features linked to healthy longevity.

AI is already being introduced into workflows in the NHS, and in the coming years it will undoubtedly become part of the day-to-day practice of most doctors. But what happens when AI contributes to patient harm? Unlike doctors, an AI system cannot be sued under English law. Legal responsibility may instead fall on the clinician, healthcare provider, developer, or manufacturer, depending on what exactly went wrong and why.NHS Resolution, which handles clinical negligence claims involving NHS trusts and general practices, has already received its first cases in which “the use of AI in delivering patient care is a potential factor.”1 The General Medical Council (GMC) has also revealed that it has received referrals about doctors misusing AI systems. These claims and complaints are likely to increase in number.1Doctors could face criticism for their AI use for several reasons, including:Using an AI system when it should not have been usedUsing an...

A gastrointestinal robotic endoscopy system has received FDA 510(k) clearance for use in diagnostic and therapeutic procedures throughout the colon.The Triton 1 System (Neptune Medical) was designed to improve endoscopic precision, stability and control and “elevate any endoscopist’s capabilities for screening, surveillance and diagnostic colonoscopies,” according to a manufacturer press release.The system also can be used for other procedures in the colon, including mucosal resections and submucosal dissections.“Bringing robotics to lower GI procedures is an exciting prospect for us,” Jason

New CFTR modulators are reshaping pediatric lung transplantation, forcing clinicians to rethink when children should be referred and listed.

Spearhead Bio says its technology can save seed breeders "years of development time and millions of dollars in crop improvement." The post Exclusive: Spearhead Bio lands oversubscribed seed round for faster, more precise gene editing tech appeared first on AgFunderNews.

Chance Miller / 9to5Mac: Apple Watch Series 12 and Ultra 4 review: new colors and materials, revamped Health Sensing System, an S11 chip, and future AI features, but few design changes  —  The Apple Watch Series 12 and Apple Watch Ultra 4 are all about what's happening underneath.  Headlined by a new Health Sensing System …

NICE has reversed its decision and approved Enhertu for NHS use in England, benefiting around 1000 women with advanced breast cancer.

Streptococcus pneumoniae is a bacterial pathogen that causes life-threatening infections, including pneumonia and meningitis.

Damage to nuclear DNA occurs constantly, and near all of it is immediately repaired. A tiny fraction lingers, however, and over time a burden of mutational damage builds up in tissues throughout the body. It is an open question as to how large a component of degenerative aging is a direct result of this damage, under normal circumstances. High rates of mutation in individuals with disabled DNA repair mechanisms shorten life span and accelerate the onset of age-related conditions, sometimes dramatically, but that doesn't necessarily mean the DNA damage is important in aging at levels exhibited in normal individuals. The best approach to firm data is to find a way to suppress or repair mutations without affecting other mechanisms, but the life-extending interventions that are […]

Sports medicine is somewhat focused on specific functional aspects of health, and so it was probably inevitable that factions in that community found the measures of life span and even health span to be lacking. Here, for example, a researcher proposes movement span as a useful concept, the period of life in which one is capable of navigating the world easily - the inverse of physical frailty, more or less. Interestingly, life span and health span in nematode worm studies of aging and longevity are already in practice forms of movement span, as manual or automated measures of worm movement is how researchers assess that the worms remain healthy and alive. How we conceptualize aging shapes how we measure it, how we respond to it, […]

As aging research shifts its focus from how long people live to how long they stay healthy, the Canadian author argues that purpose and connection deserve a place next to exercise and sleep.

arXiv:2609.18282v1 Announce Type: new Abstract: Large language models are increasingly used to generate and evaluate online content, yet it remains unclear whether the qualities they associate with higher engagement match what real users respond to. We study this question using 1.17 million answers to 25,978 questions from Zhihu, Quora, and Reddit, comparing real platform answers and AI-generated answers across four within-question engagement levels. We introduce Ontological Preference Measurement, which represents answers along three dimensions: logic, affect, and expression. We find a systematic gap between AI preference and real user engagement: as target engagement increases, LLMs add more explicit logical structure, while real user engagement is more strongly associated with affective and expressive salience. We call this tendency logic overbinding. Based on this diagnosis, we propose Ontology-Masked Reasoning Autoencoding (OMRA), a controlled intervention that masks and

arXiv:2609.18134v1 Announce Type: new Abstract: Methodological progress in artificial intelligence (AI) for electronic health records (EHRs) depends on our ability to determine which algorithms work better, and under which conditions. However, such progress is thought to be hindered by difficulties in reproducibility and in defining clinically meaningful evaluation tasks. We empirically study these barriers by re-implementing 12 historical and recent algorithms within a shared evaluation framework and evaluating them on two clinical datasets, MIMIC-IV and NWICU. We compare two complementary task families: expert-authored clinically meaningful tasks and generated tasks defined from randomly sampled event codes and prediction horizons. We ask whether relative algorithms comparisons transfer across task families and datasets, whether residual task heterogeneity contains useful methodological structure, and what a controlled comparison reveals about progress over the last decade. We find

arXiv:2609.17710v1 Announce Type: new Abstract: Community health workers (CHWs) in the Global South increasingly encounter AI-powered tools, yet the counseling work central to their role remains largely unsupported. We study communication practices among Accredited Social Health Activists (ASHAs) in rural Rajasthan, India, through simulated family-planning calls, semi-structured interviews, and an LLM chatbot roleplay design-probe with 20 participants. In calls, ASHAs often responded to social or material concerns by shifting to health-risk information, denying concerns, promising unspecified help, or listing medical solutions with limited explanation. A smaller set of responses instead engaged concerns, sought permission before involving family members, or left decisions with beneficiaries. We interpret these patterns through Motivational Interviewing, emphasizing restraint from correcting, persuading, or over-solving. Drawing across observed calls, interviews, and probe reactions,

In Switzerland, around 2,400 children are born as twins every year. When the fetuses share a placenta, they are connected to one another via blood vessels.

Incorporating a free smartphone app featuring AI-driven health coaching, blood pressure monitoring, and behavioral incentives into a hospital's existing clinical workflows helps patients make meaningful reductions in blood pressure, findings that suggest that digital apps may offer an effective means of extending care beyond the clinic when incorporated into treatment plans.

iOS 27.2 Beta Previews New Apple Intelligence Health App  MacRumorsThe Apple Watch 'Always-Listening' Features Should Worry Every Lawyer, Expert Says  Law.comApple Watch Ultra 4 vs. Apple Watch Ultra 3: Apple's premium smartwatch  AppleInsiderHere's Why a New Apple Watch Charging Puck Was Just Released  MacRumorsHow to turn off the new 'always listening' feature on Apple Watches  USA Today

iOS 27.2 Beta Previews New Apple Intelligence Health App  MacRumorsThe Apple Watch 'Always-Listening' Features Should Worry Every Lawyer, Expert Says  Law.comApple Watch Ultra 4 vs. Apple Watch Ultra 3: Apple's premium smartwatch  AppleInsiderHere's Why a New Apple Watch Charging Puck Was Just Released  MacRumorsHow to turn off the new 'always listening' feature on Apple Watches  USA Today

More than 100,000 people in the country are over 100 years old

Artificial intelligence is rapidly becoming part of how people seek, interpret and act on health information. Yet the technology is advancing faster than the evidence needed to determine whether these systems actually help people understand what matters, make informed health decisions and know what to do next.

Human brain cells transplanted into mice in ‘most extensive’ integration ever  NatureDevelopmental xenocortication using human-derived organoids in mice  NatureStanford Grows Human Brain Tissue Inside Mice in Science Breakthrough  YahooPart-human part-mouse brain developed in science breakthrough  BBCScientists Fuse Human Neurons Into the Brains of Mice  The New York Times

Human brain cells transplanted into mice in ‘most extensive’ integration ever  NatureDevelopmental xenocortication using human-derived organoids in mice  NatureStanford Grows Human Brain Tissue Inside Mice in Science Breakthrough  YahooPart-human part-mouse brain developed in science breakthrough  BBCScientists Fuse Human Neurons Into the Brains of Mice  The New York Times

A new genome-editing method, prime assembly, precisely inserts long DNA sequences into targeted genomic locations, potentially enabling mutation-agnostic gene therapies for diverse genetic diseases with fewer individualized edits. The post Prime Assembly Expands Genome Editing with Precise, Large-Scale DNA Integration appeared first on GEN - Genetic Engineering and Biotechnology News.

Somewhere in the world, a woman over 50 will have fractured a bone by the time you finish reading this sentence due to osteoporosis, a silent bone disease that can weaken the structural integrity of the skeletal system and a person's quality of life. The disease weakens bones and makes them more likely to break because of reduced bone mineral density and bone mass, and it affects an estimated 75 million people across Europe, the USA, and Japan.

The latest news and headlines from Yahoo! News. Get breaking news stories and in-depth coverage with videos and photos.

The latest news and headlines from Yahoo! News. Get breaking news stories and in-depth coverage with videos and photos.

Today, the American Association for Cancer Research (AACR) released the 16th edition of its annual Cancer Progress Report.

The number of people aged 100 or older in Japan surpassed a record 100,000 this year, the latest government figures show, underscoring the country’s rapidly aging and declining population. The Health and Welfare Ministry statistics show Japan now has 107,677 centenarians, up 7,914 from the previous year and exceeding the 100,000 mark for the first […] The post Centenarians living in Japan exceed 100,000 for the first time appeared first on Egyptian Gazette.

Less than a second. That’s how long it takes for an emerging AI tool to detect signs of endometriosis through one simple scan. It’s a much faster process than the current seven-year wait for surgery and less invasive.

Artificial intelligence (AI) scribes can reduce the time physicians spend documenting patient visits by 69.1% during simulated primary care appointments, according to research led by University of Toronto Ph.D. student LaShawn Murray.

Records released by EFF show vendors in Medicare's AI-assisted WISeR prior authorization pilot often missed a 72-hour goal, with one request unanswered for 83 days.

The number of people aged 100 or older in Japan surpassed a record 100,000 this year, the latest government figures show, underscoring the country’s rapidly aging and declining population. The Health and Welfare Ministry statistics show Japan now has 107,677 centenarians, up 7,914 from the previous year and exceeding the 100,000 mark for the first […] The post Centenarians living in Japan exceed 100,000 for the first time appeared first on Egyptian Gazette.

The FDA granted de novo authorization to Queen of Hearts, an AI EKG model for heart attack triage. What the evidence shows and what patients should know.

arXiv:2609.17338v1 Announce Type: new Abstract: Software clones are fragments of code that are similar or functionally equivalent to each other. They pose significant challenges for maintenance, refactoring, and bug detection. Detecting Type-IV clones, which are semantically equivalent but may differ syntactically, is particularly difficult for traditional token- or syntax-based methods. Recent machine learning approaches rely on contrastive learning, which requires careful negative sampling and can introduce bias. In this paper, we propose LWVIC4Code, a non-contrastive representation learning approach specifically designed for Type-IV clone detection. Building on the Variance-Invariance-Covariance Regularization (VICReg) framework and prior layer-wise VICReg training, LWVIC4Code introduces cross-layer consistency regularization and depth-dependent layer weighting to progressively refine semantic information across transformer layers, producing robust and discriminative code

arXiv:2609.17223v1 Announce Type: new Abstract: Medical AI models hold immense potential to improve patient outcomes, but they are also known to unintentionally memorise individual records from their training datasets. While such memorisation has been linked to targeted privacy attacks, its consequences for clinical deployment, where patients may be assessed by a model that saw their historical data during training, remain poorly understood. Here we show that predictions on a patient's unseen future data can change significantly if a model observed that same patient's anonymised historical data during training, a phenomenon we term "memorisation bias". We demonstrate that this bias exists across diverse data modalities and model architectures, and over prolonged time spans: in some cases, memorisation bias persists on future records acquired decades after the historical records used for training. Moreover, in simulated prospective deployment, memorisation bias has asymmetric effects

Public comments have closed on Medicare's proposed Software as a Medical Service category. Some algorithm-based lab analyses could incur patient copays.

ByteDance closed a $290M funding round for Anew Labs, its newly spun-off AI drug discovery unit, at a $1.5B valuation, Reuters reports, citing two sources familiar with the matter. Moreover, the company that owns TikTok will retain 56% of the business after this round, according to the same sources.  According to the same reporting, HSG, […] This story continues at The Next Web

Tokyo, Japan —  Japan has been gripped by a declining population for decades, but one age group is adding new members and there are more of them than ever. For the first time in Japan, the number of people aged 100 or older has surpassed more than 100,000 – a new record in the country known … The post For the first time, Japan has more than 100,000 centenarians appeared first on Egypt Independent.

Streptococcus pneumoniae is a bacterial pathogen that causes life-threatening infections, including pneumonia and meningitis. These infections are commonly treated with antibiotics, but antibiotics are becoming less effective against S. pneumoniae over time because of changes in the pathogen that cause drug resistance. This phenomenon, called antimicrobial resistance, is resulting in significant health care costs and deaths around the world. In a new study published by Wiley in Advanced Science, researchers used artificial intelligence (AI) to identify approved drugs that may be effective against S. pneumoniae.

Kane Wu / Reuters: Sources: Shanghai-based Anew Labs, a ByteDance spinoff using AI for drug discovery, raised $290M from HSG, IDG Capital, and others at a $1.5B valuation  —  Chinese social media and internet company ByteDance has completed a $290 million fundraising for its AI drugmaking unit after spinning …

Consumers have placed their personal physicians above all health care touchpoints in their lives when it comes to trust stewards of and for health care information and data protection. More consumers have adopted the use of AI in every day life across many life flows, including their health care. The latest riff from the annual Edelman Trust Barometer 2026 highlights a look into health and trust in concert with the Yale School of Public Health. And they found that among AI users, one-half think AI can address their health concerns at least as well as doctors can.             To gain global health citizens’ perspectives on trust, health, and AI, the Edelman team polled 12,998 adults in 13 countries between late February and mid-March 2026. Countries covered included Australia, Brazil, Canada, France, Germany, India, Indonesia, Japan, Mexico, S. Africa, S. Korea, the UK and the United States. The first chart reveals that 1-in-2 AI users’ views on

A new 3D-structure of a cancer-linked protein bound to its cellular partner reveals details of how the protein binds to chromosomes and could offer insights for future disease treatments.

AI agents could reliably support diagnoses and clinical decision-making in the future—provided sensitive health data are protected and clinicians can assess the reliability of individual AI-generated results. Researchers at the Else Kröner Fresenius Center (EKFZ) for Digital Health at TU Dresden and Dresden University Hospital have developed an on-premises medical AI system that addresses both challenges. Their findings have been published in the journal Nature Medicine.

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Teens' AI use becomes problematic when a chatbot replaces a trusted adult or peer, according to psychiatrists.

After an injury, DNA not only alters its activity but also the way it is organized spatially within the cell nucleus.

A few species of hydra are immortal in their normal environmental conditions, meaning that function does not decline over time and mortality risk does not increase over time. Researchers spent a good deal of time taking care of hundreds of hydra some years ago to demonstrate that this is the case. Hydra are lower animals, essentially a bundle of stem cells capable of regenerating and replacing any part of their bodies, somewhat analogous to an ambulatory embryo. It is an open question as to whether anything we can learn from their biochemistry can be useful in human medicine. In today's open access paper, researchers report on the employment of telomerase by hydra. Telomeres are repeated sequences at the end of chromosomes that shorten with each […]

The biologic drug interferon-alpha can benefit patients with blood cancers called myeloproliferative neoplasms by forcing mutant blood stem cells to become shorter-lived white blood cells, according to a study by Weill Cornell Medicine investigators. Because the broad activity of interferon-alpha can induce significant side effects, developing more focused strategies based on these mechanistic findings could meet an important need in cancer therapy.

During transplantation, blood flow to the donor liver must stop as it's moved to the recipient. Once transplanted, oxygen-rich blood is restored, yet doing so can cause what is called ischemia-reperfusion injury. To protect transplanted livers from this tissue damage, researchers at The Hospital for Sick Children (SickKids) have discovered a way to protect dying cells from rupturing and affecting the surrounding area.

Targeting the gut microbiome with fecal microbiota transplantation (FMT) may help cancer patients with immunotherapy-related colitis avoid the need for steroids and other immunosuppressive treatments, according to researchers at The University of Texas MD Anderson Cancer Center.

Insilico Medicine, a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, today announced Longevity Vaccines, a research initiative developing treatments that direct a patient's own immune cells to eliminate the earliest cellular drivers of age-related disease.

Preeclampsia is one of the leading causes of pregnancy-related death. Even after a healthy delivery, mother and baby can go home only to show signs of a postpartum hypertensive disorder days or weeks later.

A National Institutes of Health (NIH)-funded scientific team has shown that a new brain-computer interface (BCI) can allow people with vocal tract and bodily paralysis to convey both speech and upper-body gestures simultaneously.

Stockholm-based Tandem Health has raised $100m in a Series B round led by the Scaleup Europe Fund, which EQT manages. The company announced the round on 14 September. Existing investors Kinnevik, Northzone, Amino Collective, and Visionaries also took part. Tandem said the deal is the fund’s first investment in healthcare. The round follows a $50m […] This story continues at The Next Web

The company anticipates its two pumps will work with a next-generation insulin dosing algorithm.

Cells become senescent constantly throughout life in response to various forms of damage and stress, ceasing replication and generating a potent mix of inflammatory signals. In youth, these cells are promptly cleared by the immune system, but with advancing age they begin to linger and accumulate. The inflammatory signaling becomes disruptive to tissue structure and function when sustained over the long term, and this is an important contribution to degenerative aging. Here, researchers show that macrophage cells in the kidney express increasing amounts of the P2RX7 receptor on the cell surface as they progress towards becoming senescent, and blocking this receptor with a suitable antagonist small molecule reduces macrophage senescence and improves kidney function. Macrophage senescence is a pathological feature in aging or diseased kidneys. […]

TIGRa, half CRISPR’s size, fits in viral vectors to boost protective genes. Its compact design could enable gene