Cancer

At 4 years, dostarlimab plus chemotherapy reduced the risk for death by two thirds among patients with dMMR/MSI-H advanced endometrial cancer, pointing to curative potential, experts say.

In mouse tests, magnet-guided algae microbots helped chemotherapy penetrate bladder tumours more deeply, cutting tumour burden after one week.

Tiny algae-based robots guided by magnets could improve bladder cancer treatment by boosting delivery of chemotherapy drugs into tumors, researchers say.

Researchers developed a versatile nanorobot with propulsion and payload modules. The two reusable modules autonomously self-assemble and could be used in medicine or industry.

Researchers created a DIA-MS atlas of 13,609 proteins across 2,856 samples from fetal, healthy adult, paired non-tumor, and tumor tissues. The resource maps tissue-specific protein patterns, cancer-associated changes, organ-specific drug-toxicity signals, and candidate therapeutic targets.

Creatine, the organic acid that is popularly taken as a supplement by athletes and bodybuilders, supercharges a critical class of immune cells that activate and prepare the body’s key cancer-fighters, according to new UCLA research.

Jeremy Clarkson announces remission from prostate cancer, crediting early detection through a routine blood test. He urges men to undergo testing, highlighting the disease's prevalence in the UK.

A team at the University of Basel, Switzerland, has developed a versatile nanorobot with propulsion and payload modules. The two reusable modules autonomously self-assemble and could be used in medicine or industry.

Researchers have concluded that nicotine vapes are likely to cause lung and oral cancers, based on evidence ranging from human biomarkers to animal and laboratory studies. The findings challenge the idea that vaping is a harmless alternative to smoking and suggest health risks may be emerging much sooner than many expected.

Scientists have discovered that a gene normally considered a DNA-protecting "good guy" can become dangerous when cells make too much of it. The gene, EXO1, acts like molecular scissors that help repair DNA, but when overproduced it starts cutting DNA it shouldn't, creating damage linked to cancer.

Scotland's cancer centres are all reporting treatment delays caused by staff shortfalls, with a new RCR census warning the situation will worsen significantly by 2030.

The cardioprotective effects of heart failure treatments in patients with cancer were demonstrated today in a presentation at ESC Cardio-Oncology 2026, the annual conference of the European Society of Cardiology's Council of Cardio-Oncology.

Kate Middleton returned to Royal Ascot, marking her first public appearance since announcing her cancer diagnosis. Her presence symbolised resilience and continuity within the royal family.

MRI provides a more reliable preoperative prediction of survival and recurrence in patients with rectal tumour than traditional histopathology.

New data suggest adding chemoradiotherapy to adjuvant gemcitabine does not improve overall survival after pancreatic cancer resection, but one subgroup appears to benefit.

Everyday viral infections may be quietly reshaping the body’s network of molecules that support cells and tissues in ways that can raise cancer risk over time

The findings from a large observational study underscore the need for randomized clinical trials to assess the relationship between GLP-1 use and outcomes in patients with cancer.

High-income countries that initiated widespread administration of the Human Papilloma Virus (HPV) vaccine in the mid-2000s have experienced substantial declines in cervical cancer cases, marking a significant achievement in medicine.

Endometrial cancer is the most common gynecologic cancer, with more than 69,000 cases diagnosed in the U.S. in 2025 and increasing up to 3% annually.

A study from the University of Calgary shows that removing a single gene makes colon cancer cells a target for immunotherapy - a fundamental breakthrough.

Carly Douglas, a South Carolina fitness influencer, passed away at 36 from gastric cancer. Her journey inspired many, and her family shared a heartfelt tribute highlighting her faith and resilience.

Researchers at the Federal University of São Paulo (UNIFESP) in Brazil have identified a molecule on the surface of cells that could be a promising therapeutic target against cancer.

Researchers at The University of Texas MD Anderson Cancer Center have developed a spatial map of muscle-invasive bladder cancer, revealing how tumor cell states, immune environments and therapeutic vulnerabilities are organized within tumors.

Researchers have found that a genetic mutation associated with a rare group of blood cancers does not always result in development of the disease.

Novocure said on Thursday that a late-stage trial showed early use of its non-invasive cancer therapy ⁠did not significantly improve overall survival in patients with newly...

THURSDAY, June 18, 2026 — The cancer diagnosis came as a shock, disrupting Morgan Newman’s plans for launching her life. It was 2015, and she was working as a dental assistant in Des Moines, Iowa, while studying to become a social worker.After an...

New research shows the HPV vaccine has prevented nearly 200 cervical cancer deaths in England, but falling vaccination rates are putting further progress at risk.

An adenoviral-based immunotherapy improved disease-free survival in men with localized intermediate- or high-risk disease, but experts had reservations.

Nearly 370,000 bottles of duloxetine have been recalled in the US due to elevated levels of a potentially cancer-causing impurity.

We already know the vaccine against human papillomavirus, or HPV, greatly reduces infections and cases of cervical cancer, and now we have the first evidence it prevents deaths too

A multimodal AI model identified a subset of men with very high-risk localized prostate cancer who derived substantial benefit from adding abiraterone to standard therapy.

Researchers developed an original technology for treating cancer using nanoparticles that carry no drugs at all, and demonstrated its effectiveness against particularly dangerous and stubborn tumors.

Researchers have developed a molecular switch that is controlled by light. It wakes lung cancer cells up from a protective dormant state so that they are more accessible for treatment.

Researchers compare success rates for addressing positive margins without intraoperative margin assessment with specimen PET-CT in patients with invasive ductal carcinoma.

As new colorectal cancer screening guidance draws attention to the growing number of testing options, the American Gastroenterological Association urges patients and primary care providers to understand how those options compare.

We already know the vaccine against human papillomavirus, or HPV, greatly reduces infections and cases of cervical cancer, and now we have the first evidence it prevents deaths too

Jeremy Clarkson reveals he has an aggressive but early-stage prostate cancer in hard-to-watch scenes from Clarkson's Farm, telling viewers from his hospital bed that he may not return for season six.

A laboratory at the Tulane University School of Medicine has enhanced its drug screening and tumor modelling workflows by adopting advanced liquid handling solutions from INTEGRA Biosciences, including the PIPETBOY GENIUS serological pipet controller and VIAFLO electronic pipettes.

In a large observational study of adults with obesity without diabetes, GLP-1 receptor agonists were associated with a 41% lower incidence of obesity-associated cancers over 2 years.

Researchers at the Medical University of Vienna have described a mechanism in metastatic colorectal cancer that has received little attention to date: a key target of existing therapies, the so-called epidermal growth factor receptor (EGFR), is likely to affect more than just the cancer cells themselves.

Early findings show efficacy of water vapor therapy for treating intermediate-risk prostate cancer with minimal procedural complications.

Guidelines on treating cancer fatigue offer little enthusiasm for methylphenidate and other stimulants. But a recent meta-analysis suggests the medications deserve a rethink.

A large study links the use of e-cigarettes after smoking cessation to higher lung cancer incidence and mortality than complete nicotine abstinence.

A major systematic review and meta-analysis links higher BMI to increased risk of 19 cancer types, including leukemia, non-Hodgkin lymphoma, bladder cancer, and glioma, which were not previously recognized in major consensus reports. The study also reveals regional and sex-based variation in cancer risk, with genetic evidence generally supporting many observational links while highlighting the need for more diverse global cohorts.

Researchers at the State University of Campinas (UNICAMP) in São Paulo, Brazil, have identified a new biomarker that may help determine the prognosis for patients with gastric cancer, the fifth most common type of cancer worldwide.

A new paper led by researchers at University of Victoria's Canadian Institute for Substance Use Research (CISUR) contributes to mounting evidence that alcohol use can cause pancreatic cancer.

KRAS‑mutant pancreatic cancer relies on caspase‑8 to evade necroptosis, according to a new study. Blocking caspase‑8 triggers cell death in mouse models and patient‑derived organoids, revealing a promising therapeutic vulnerability. The post Pancreatic Cancer Cell Death Triggered by Caspase‑8 Blockade in Preclinical Models appeared first on GEN - Genetic Engineering and Biotechnology News.

Cancer cells are remarkably good at adapting to stress. When treatments damage them, they often find new ways to survive, fueling drug resistance and disease progression.

Researchers at the Purdue Institute for Cancer Research (PICR) have developed a next-generation technology platform designed to dramatically accelerate one of the slowest and most challenging stages of cancer drug discovery: identifying promising compounds that could eventually become new therapies.

Tiger Woods is supporting Vanessa Trump through her cancer treatment while managing his own legal and rehab challenges, highlighting their relationship's resilience amid personal crises.

A large analysis finds sugar-sweetened beverages are linked to two types of liver cancer.

Researchers developed ResMap, a community resource providing both a standardized experimental framework and quantitative dataset for systematic comparison of persister cell vulnerabilities across cancer contexts. The post Therapy-Resistant Residual Cancer Cell Dependencies Mapped appeared first on GEN - Genetic Engineering and Biotechnology News.

Ultrasmall silica nanoparticles induce ferroptosis and reshape the prostate tumor microenvironment, reversing myeloid suppression and boosting responses to checkpoint blockade. The post Silica Nanoparticles Induce Ferroptosis, Reprogram Immunity in Prostate Cancer Models appeared first on GEN - Genetic Engineering and Biotechnology News.

Dr. Dan Landau, the Bibliowicz Family Professor of Medicine, and a member of the Sandra and Edward Meyer Cancer Center and the Englander Institute for Precision Medicine at Weill Cornell Medicine, has received a Lotus Award from the Pershing Square Foundation for research aimed at uncovering new immunotherapy targets in ovarian cancer.

A study by the University of Barcelona has discovered why the two main types of lung cancer — adenocarcinoma of the lung and squamous cell carcinoma — respond differently to anti-angiogenic therapy, that is, drugs that block the formation of new blood vessels that tumors need in order to grow.

A type of white blood cell in the immune system, known as neutrophils, can make cancer immunotherapy less effective. This is shown in a new study from Karolinska Institutet published in the journal Immunity.

Dual-target CAR T cell therapy for recurrent glioblastoma (GBM), delivered directly into the cerebrospinal fluid (CSF), triggers a broad immune response, with natural killer (NK) cell activation linked to better patient outcomes and longer overall survival.

New research in the June 2026 issue of JNCCN-Journal of the National Comprehensive Cancer Network finds that small, targeted prompts delivered to both patients and providers at the right moment can significantly increase the number of serious illness conversations that take place.

The CAPItello-281 trial reported a 19% improvement in radiographic progression-free survival.

Vanessa Trump says she is recovering from surgery and preparing for the next stage of breast cancer treatment as Tiger Woods returns to the US after rehab.

New data with longer-term follow-up suggest that PSA screening probably lowers prostate cancer mortality — but experts stress the gains are modest and come with risk for overdiagnosis.

Experts offer advice for treating symptoms of ovarian, breast, and other cancers that are not driven by depression and explain why it’s essential to discern the difference.

Cancer care is becoming too complex for any one clinician to track alone, making AI an increasingly valuable tool in modern oncology.

Researchers from ETH Zurich have developed a molecular switch that is controlled by light. It wakes lung cancer cells up from a protective dormant state so that they are more accessible for treatment.

Pain that interferes with daily functioning is associated with higher odds of frailty and its progression in adult survivors of childhood cancer.

New research to be presented today (Monday) at the annual conference of the European Society of Human Genetics shows that a cancer patient's genetic ancestry can have a significant effect both on how their disease progresses and their survival. In the largest study of its kind, researchers examined nearly 1,900 specific genetic changes in tumors in order to measure whether certain mutations were more common in patients with different historic geographic origins.

Longer lifetime exposure to female hormones may increase the risk of thyroid cancer in women, according to a study being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

Cancer drugs can shrink fast-growing tumors. But sometimes a few tumor cells survive. These "persister" cells seed new tumors, forcing cancer patients into arduous cycles of testing and treatment.

A molecular geneticist at Montana State University has discovered a cellular process once believed impossible by scientists – the creation of the amino acid cysteine within a living cell when the cell's primary systems to do so fail. The discovery may one day lead to new cancer treatments.

A carefully designed metal-free carbon monoxide prodrug may help prevent some of the deadliest forms of cancer from spreading, according to researchers at Weill Cornell Medicine.

Researchers discovered that mutations linked to blood cancers may help trigger Alzheimer’s disease by creating overly inflammatory immune cells in the brain. The unexpected finding could lead to new blood-based screening methods and potential treatments borrowed from cancer medicine.

A study of 4.5 million people suggests that ex-smokers who take up vaping are more at risk of dying from lung cancer than people who quit without the use of e-cigarettes

Studies on the health risks of ultraprocessed foods grab headlines, but how good — and useful — is the evidence?

The risk for extrahepatic cancers varies among subgroups of steatotic liver disease, with the highest risk seen in patients with metabolic dysfunction and alcohol-associated liver disease.

The Alliance for Clinical Trials in Oncology (Alliance) today announced that the U.S. Food and Drug Administration has accepted for review Genentech's supplemental Biologic License Application for their immunotherapy drug atezolizumab (Tecentriq®) for the treatment of patients with stage III colon cancer with deficient deoxyribonucleic acid (DNA) mismatch repair (dMMR).

A research team in Japan has developed an efficient, minimally invasive cancer detection device that uses high-performance zinc oxide nanowires to selectively capture extracellular vesicles (EVs) from bodily fluids.

A study of 4.5 million people suggests that ex-smokers who take up vaping are more at risk of dying from lung cancer than people who quit without the use of e-cigarettes

Experts are trying to find the best way to screen for prostate cancer, since blood tests alone are not accurate enough for most men.

Women taking the drug, which is kinder on the body, tell the BBC it has given them their lives back.

Some men in England with the disease will now be offered an advanced form of treatment on the NHS.

A new study by investigators from Mass General Brigham Cancer Institute found that an ultrasensitive blood test called HPV-DeepSeek could help identify which people with HPV-associated head and neck cancer still had cancer cells in their bodies after surgery and may benefit the most from additional treatments. Their results are published in Science Translational Medicine.

Cancer cells often survive treatment by fixing the DNA damage that therapy is meant to cause. Researchers found that UNI418 can disrupt this repair ability, leaving cancer cells more exposed. When combined with a PARP inhibitor, it helped resistant cancer cells respond to treatment again. The findings point to a new strategy for overcoming cancer drug resistance.

New research co-led by Indiana University School of Medicine scientists presents a significant step toward more precise and effective cancer treatments by using a breakthrough method to deliver therapies directly to cancer cells. The study was recently published in ACS Nano.

Nuvalent’s pipeline is headed by the ROS1 inhibitor zidesamtinib (NVL-520) and the ALK inhibitor eladalkib (NVL-655), which according to the company represent potential best-in-class, next-generation, highly selective treatments for NSCLC. Both are brain penetrant. The FDA has set target decision dates of September 18 for zidesamtinib and November 27 for neladalkib. The post GSK to Acquire Nuvalent for $10.6B, Boosting Cancer Pipeline with Precision NSCLC Treatments appeared first on GEN - Genetic Engineering and Biotechnology News.

A recent, 10-year study from California identified many known or suspected carcinogens in artificial turf. Does it pose a danger?

Conventional cancer treatments, such as chemotherapy, often lack specificity and can damage both cancerous and healthy cells, leading to severe side effects.

Daniel Daneshvar, MD, PhD, director of the HealthSpan Lab and Chief of the Department of Physical Medicine and Rehabilitation at Mass General Brigham, and Charlotte Luster, of the HealthSpan Lab, are the senior and lead authors of a paper published in Neuroepidemiology, "Brain Cancer Mortality following Traumatic Brain Injury (TBI): A TBI Model Systems Study."

Conventional cancer treatments, such as chemotherapy, often lack specificity and can damage both cancerous and healthy cells, leading to severe side effects. With this in mind, researchers at Indian Institute of Technology Gandhinagar (IITGN) have developed DNA nanostructures called tetrahedrons and modified them by attaching a vitamin E-derived molecule called alpha-tocopherol succinate (αT), which can disrupt vital functions inside cancer cells while acting protectively in healthy cells. By incorporating αT into the DNA tetrahedrons, the researchers significantly enhanced cellular uptake and improved anticancer efficacy, resulting in more selective and effective elimination of cancer cells.

WEDNESDAY, June 10, 2026 — If you regularly drink soda or other sugary beverages, a new study may give you a reason to cut back.Researchers analyzed dietary data from more than 1.5 million adults across 11 long-term investigations. They wanted to...

A gorilla adenovirus originally developed for vaccines is showing unexpected promise as a cancer therapy—one whose therapeutic properties may be baked into its native biology rather than engineered in. The post Gorilla Adenovirus Brings Natural Edge to Cancer Therapy appeared first on GEN - Genetic Engineering and Biotechnology News.

Eligible men with early prostate cancer can now be offered a high-precision radiotherapy technique on the NHS in England.

Tiger Woods and Vanessa Trump face separate health challenges, with Woods undergoing treatment abroad and Trump battling breast cancer.

Patients with cancer who suffer an acute ischaemic stroke face higher odds of in-hospital death and bleeding after recanalisation therapy, with outcomes varying by cancer subtypes.

A new AI model reliably identifies hidden pancreatic ductal adenocarcinoma on routine CT scans months before the clinical diagnosis of the disease.

The technology that rushed COVID-19 vaccines to clinics in record time has found a second calling. mRNA-based treatments

A large population study of young Black women aged 50 years or younger with invasive breast cancer highlights the importance of genetic testing in this population.

“Chemo brain” affects up to 80% of people receiving chemotherapy, making everyday tasks harder. In a new trial, cancer patients who followed a home-based exercise program showed better attention and fewer noticeable cognitive problems than those who received a placebo. Low-dose ibuprofen also improved some cognitive measures, though its effects were less consistent.

Scientists have uncovered a hidden immune system "brake" that may help cancers avoid being destroyed. The molecule, called SLAMF6, weakens the body's cancer-fighting T cells and can leave them exhausted over time. Researchers developed antibodies that block this brake, allowing immune cells to stay stronger and attack tumors more effectively in mice.

Wildland firefighters are exposed to a mix of harmful chemicals in the smoke they breathe and the ash and soot that gets on their clothing. Over long assignments fighting fires that can last for days to weeks, those chemicals can be absorbed by their skin.